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26-Week oral safety study in macaques for transgenic rice containing major human T-cell epitope peptides from Japanese cedar pollen allergens

artículo científico publicado en 2009

A rice transmembrane bZIP transcription factor, OsbZIP39, regulates the endoplasmic reticulum stress response

artículo científico publicado en 2011

A rice-based edible vaccine expressing multiple T cell epitopes induces oral tolerance for inhibition of Th2-mediated IgE responses

artículo científico publicado en 2005

A rice-based edible vaccine expressing multiple T-cell epitopes to induce oral tolerance and inhibit allergy

artículo científico publicado en 2007

A rice-based oral cholera vaccine induces macaque-specific systemic neutralizing antibodies but does not influence pre-existing intestinal immunity

artículo científico publicado en 2009

A transgenic rice seed accumulating an anti-hypertensive peptide reduces the blood pressure of spontaneously hypertensive rats

artículo científico publicado en 2006

A whole-genome analysis of a transgenic rice seed-based edible vaccine against cedar pollen allergy

scientific article published on 15 August 2013

Agrobacterium-mediated co-transformation of rice using two selectable marker genes derived from rice genome components

artículo científico publicado en 2012

Agrobacterium-mediated transformation of a low glutelin mutant of 'Koshihikari' rice variety using the mutated-acetolactate synthase gene derived from rice genome as a selectable marker

artículo científico publicado en 2007

Allergen-specific immunotherapy with plant-based oral vaccines

artículo científico publicado en 2009

Allergenic potential of rice-pollen proteins: expression, immuno-cross reactivity and IgE-binding.

artículo científico publicado en 2013

An overview on the strategies to exploit rice endosperm as production platform for biopharmaceuticals

artículo científico publicado en 2017

Analysis of ER stress in developing rice endosperm accumulating beta-amyloid peptide

scientific article published on 15 March 2010

Analysis of Recombinant Proteins in Transgenic Rice Seeds: Identity, Localization, Tolerance to Digestion, and Plant Stress Response

artículo científico publicado en 2016

Analysis of rice ER-resident J-proteins reveals diversity and functional differentiation of the ER-resident Hsp70 system in plants

artículo científico publicado en 2013

Antihypertensive activity of transgenic rice seed containing an 18-repeat novokinin peptide localized in the nucleolus of endosperm cells

artículo científico publicado en 2010

Antisense inhibition of isoamylase alters the structure of amylopectin and the physicochemical properties of starch in rice endosperm

artículo científico publicado en 2003

Avidin expressed in transgenic rice confers resistance to the stored-product insect pests Tribolium confusum and Sitotroga cerealella.

artículo científico publicado en 2005

Aβ induces oxidative stress in senescence-accelerated (SAMP8) mice.

artículo científico publicado en 2015

Biochemical safety evaluation of transgenic rice seeds expressing T cell epitopes of Japanese cedar pollen allergens

artículo científico publicado en 2006

Biopharming to increase bioactive peptides in rice seed.

scientific article published on July 2008

C-terminal extension of rice glutamate decarboxylase (OsGAD2) functions as an autoinhibitory domain and overexpression of a truncated mutant results in the accumulation of extremely high levels of GABA in plant cells

artículo científico publicado en 2007

Cereal seed storage protein synthesis: fundamental processes for recombinant protein production in cereal grains.

artículo científico publicado en 2010

Change in subcellular localization of overexpressed vaccine peptide in rice endosperm cell that is caused by suppression of endogenous seed storage proteins

artículo científico publicado en 2018

Characterization of IRE1 ribonuclease-mediated mRNA decay in plants using transient expression analyses in rice protoplasts.

artículo científico publicado en 2016

Characterization of a new rice glutelin gene GluD-1 expressed in the starchy endosperm

artículo científico publicado en 2008

Cis-element of the rice PDIL2-3 promoter is responsible for inducing the endoplasmic reticulum stress response.

artículo científico publicado en 2013

Co-expression of soybean glycinins A1aB1b and A3B4 enhances their accumulation levels in transgenic rice seed

artículo científico publicado en 2008

Comparison of promoters in transgenic rice

artículo científico publicado en 2008

Compensation and interaction between RISBZ1 and RPBF during grain filling in rice.

artículo científico publicado en 2009

Compensatory rebalancing of rice prolamins by production of recombinant prolamin/bioactive peptide fusion proteins within ER-derived protein bodies

artículo científico publicado en 2017

Concentrated protein body product derived from rice endosperm as an oral tolerogen for allergen-specific immunotherapy--a new mucosal vaccine formulation against Japanese cedar pollen allergy

artículo científico publicado en 2015

Curative strategy against allergic and infection diseases using rice-based edible vaccine

artículo científico publicado en 2006

Deposition mode of transforming growth factor-β expressed in transgenic rice seed.

artículo científico publicado en 2016

Deposition of a recombinant peptide in ER-derived protein bodies by retention with cysteine-rich prolamins in transgenic rice seed

artículo científico publicado en 2009

Development of Rice-Seed-Based Oral Allergy Vaccines Containing Hypoallergenic Japanese Cedar Pollen Allergen Derivatives for Immunotherapy

artículo científico publicado en 2019

Development of a novel transgenic rice with hypocholesterolemic activity via high-level accumulation of the α' subunit of soybean β-conglycinin

article

Development of a rice-based peptide vaccine for Japanese cedar and cypress pollen allergies

artículo científico publicado en 2014

Development of an efficient agrobacterium-mediated gene targeting system for rice and analysis of rice knockouts lacking granule-bound starch synthase (Waxy) and β1,2-xylosyltransferase

artículo científico publicado en 2012

Development of transgenic rice containing a mutated beta subunit of soybean beta-conglycinin for enhanced phagocytosis-stimulating activity

artículo científico publicado en 2010

Development of transgenic rice expressing mite antigen for a new concept of immunotherapy.

artículo científico publicado en 2009

Development of transgenic rice seed accumulating a major Japanese cedar pollen allergen (Cry j 1) structurally disrupted for oral immunotherapy

artículo científico publicado en 2007

Differences in transcriptional regulatory mechanisms functioning for free lysine content and seed storage protein accumulation in rice grain

artículo científico publicado en 2010

Differential effects of a transgene to confer low phytic acid in caryopses located at different positions in rice panicles.

artículo científico publicado en 2009

Downregulation of IL-13 gene transcription by T-bet in human T cells

artículo científico publicado en 2008

ER stress response induced by the production of human IL-7 in rice endosperm cells

artículo científico publicado en 2013

Effect of overexpression of kinase- or RNase-deficient OsIRE1 on the endoplasmic reticulum stress response in transgenic rice plants

scientific article published on 18 June 2013

Efficacy of oral immunotherapy with a rice-based edible vaccine containing hypoallergenic Japanese cedar pollen allergens for treatment of established allergic conjunctivitis in mice.

artículo científico publicado en 2017

Efficient induction of oral tolerance by fusing cholera toxin B subunit with allergen-specific T-cell epitopes accumulated in rice seed

artículo científico publicado en 2008

Emerging features of ER resident J-proteins in plants

artículo científico publicado en 2014

Endosperm tissue is good production platform for artificial recombinant proteins in transgenic rice

artículo científico publicado en 2007

Evaluation of allergenic potential for rice seed protein components utilizing a rice proteome database and an allergen database in combination with IgE-binding of recombinant proteins

artículo científico publicado en 2016

Evaluation of basophil activation caused by transgenic rice seeds expressing whole T cell epitopes of the major Japanese cedar pollen allergens

artículo científico publicado en 2019

Evaluation of tissue specificity and expression strength of rice seed component gene promoters in transgenic rice

scientific article published on 01 March 2004

Expression and Purification of Recombinant Mouse Interleukin-4 and -6 from Transgenic Rice Seeds

artículo científico publicado en 2016

Expression of ER quality control-related genes in response to changes in BiP1 levels in developing rice endosperm

artículo científico publicado en 2011

Expression of OsBiP4 and OsBiP5 is highly correlated with the endoplasmic reticulum stress response in rice

artículo científico publicado en 2012

Expression of hypoallergenic Der f 2 derivatives with altered intramolecular disulphide bonds induces the formation of novel ER-derived protein bodies in transgenic rice seeds

artículo científico publicado el 29 de febrero de 2012

Expression of the small peptide GLP-1 in transgenic plants

artículo científico publicado en 2005

Expression of unprocessed glutelin precursor alters polymerization without affecting trafficking and accumulation

artículo científico publicado en 2009

Extraction and purification of human interleukin-10 from transgenic rice seeds

artículo científico publicado en 2010

Foreign gene products can be enhanced by introduction into low storage protein mutants

scientific article published on 01 November 2003

Functional integration between defence and IRE1-mediated ER stress response in rice

artículo científico publicado en 2012

Generation mechanism of novel, huge protein bodies containing wild type or hypoallergenic derivatives of birch pollen allergen Bet v 1 in rice endosperm.

artículo científico publicado en 2014

Generation of Transgenic Rice Lines with Reduced Contents of Multiple Potential Allergens Using a Null Mutant in Combination with an RNA Silencing Method

Generation of a transgenic rice seed-based edible vaccine against house dust mite allergy

artículo científico publicado en 2007

Generation of stable 'low phytic acid' transgenic rice through antisense repression of the 1D-myo-inositol 3-phosphate synthase gene (RINO1) using the 18-kDa oleosin promoter

artículo científico publicado en 2008

Generation of transgenic rice with reduced content of major and novel high molecular weight allergens.

artículo científico publicado en 2014

Genetically modified rice seeds accumulating GLP-1 analogue stimulate insulin secretion from a mouse pancreatic beta-cell line.

artículo científico publicado en 2005

High accumulation of bioactive peptide in transgenic rice seeds by expression of introduced multiple genes

artículo científico publicado en 2006

High-level production of lactostatin, a hypocholesterolemic peptide, in transgenic rice using soybean A1aB1b as carrier

artículo científico publicado el 6 de noviembre de 2012

Higher-level accumulation of foreign gene products in transgenic rice seeds by the callus-specific selection system.

artículo científico publicado en 2009

Hypotensive Activity of Transgenic Rice Seed Accumulating Multiple Antihypertensive Peptides

artículo científico publicado en 2020

Identification of a cis-element that mediates multiple pathways of the endoplasmic reticulum stress response in rice

scientific article published on 07 March 2013

Immunological and Symptomatic Effects of Oral Intake of Transgenic Rice Containing 7 Linked Major T-Cell Epitopes from Japanese Cedar Pollen Allergens

artículo científico publicado en 2020

Improvement of production yield and extraction efficacy of recombinant protein by high endosperm-specific expression along with simultaneous suppression of major seed storage proteins

artículo científico publicado en 2020

Improving rice nutrition: challenges and practical approaches for iron fortification.

artículo científico publicado en 2005

Increased lysine content in rice grains by over-accumulation of BiP in the endosperm

artículo científico publicado en 2010

Increasing the production yield of recombinant protein in transgenic seeds by expanding the deposition space within the intracellular compartment

artículo científico publicado el 5 de abril de 2013

Inhibition of allergen-induced airway inflammation by low-dose oral immunotherapy with transgenic rice seeds independently of immunoglobulin e synthesis

artículo científico publicado en 2012

Iron accumulation does not parallel the high expression level of ferritin in transgenic rice seeds

artículo científico publicado en 2005

Multiple roles of the ER stress sensor IRE1 demonstrated by gene targeting in rice

artículo científico publicado en 2012

N-Glycosylation and N-Glycan Moieties of CTB Expressed in Rice Seeds

artículo científico publicado el 1 de julio de 2013

Oral Immunotherapy for Allergic Conjunctivitis Using Transgenic Rice Expressing Hypoallergenic Antigens

artículo científico publicado en 2018

Oral MucoRice expressing double-mutant cholera toxin A and B subunits induces toxin-specific neutralising immunity

artículo científico publicado en 2009

Oral immunogenicity and protective efficacy in mice of transgenic rice plants producing a vaccine candidate antigen (As16) of Ascaris suum fused with cholera toxin B subunit

artículo científico publicado en 2008

Oral immunotherapy against a pollen allergy using a seed-based peptide vaccine

scientific article published on 01 September 2005

Oral immunotherapy with transgenic rice seed containing destructed Japanese cedar pollen allergens, Cry j 1 and Cry j 2, against Japanese cedar pollinosis

artículo científico publicado en 2012

OsERdj7 is an ER-resident J-protein involved in ER quality control in rice endosperm

artículo científico publicado en 2019

OsHrd3 is necessary for maintaining the quality of endoplasmic reticulum-derived protein bodies in rice endosperm

artículo científico publicado en 2015

Overexpression of BiP has inhibitory effects on the accumulation of seed storage proteins in endosperm cells of rice

artículo científico publicado en 2009

Overexpression of OsRab7B3, a small GTP-binding protein gene, enhances leaf senescence in transgenic rice

artículo científico publicado en 2012

Peptide immunotherapy for allergic diseases using a rice-based edible vaccine

artículo científico publicado en 2006

Prevention of allergic asthma by vaccination with transgenic rice seed expressing mite allergen: induction of allergen-specific oral tolerance without bystander suppression

artículo científico publicado en 2011

Prevention of allergic conjunctivitis in mice by a rice-based edible vaccine containing modified Japanese cedar pollen allergens

artículo científico publicado en 2015

Production of Ascaris suum As14 protein and its fusion protein with cholera toxin B subunit in rice seeds

artículo científico publicado en 2009

Production of Rice Seed-Based Allergy Vaccines

artículo científico publicado en 2016

Promoter shuffling at a nuclear gene for mitochondrial RPL27. Involvement of interchromosome and subsequent intrachromosome recombinations

scientific article published on 07 April 2006

Prophylactic and Therapeutic Effects of Oral Immunotherapy on Birch Pollen-Induced Allergic Conjunctivitis in Mice with a Rice-Based Edible Vaccine Expressing a Hypoallergenic Birch Pollen Allergen

artículo científico publicado en 2021

Prophylactic effect of the oral administration of transgenic rice seeds containing altered peptide ligands of type II collagen on rheumatoid arthritis.

artículo científico publicado en 2014

RNA sequencing-mediated transcriptome analysis of rice plants in endoplasmic reticulum stress conditions

artículo científico publicado en 2014

RNA silencing induced by an artificial sequence that prevents proper transcription termination in rice.

artículo científico publicado en 2012

RNA silencing is induced by the expression of foreign recombinant products in transgenic rice

artículo científico publicado en 2014

Recent advances in understanding the control of secretory proteins by the unfolded protein response in plants.

artículo científico publicado en 2013

Recombinant protein yield in rice seed is enhanced by specific suppression of endogenous seed proteins at the same deposit site

artículo científico publicado en 2012

Reducing rice seed storage protein accumulation leads to changes in nutrient quality and storage organelle formation

artículo científico publicado en 2010

Reduction of 13 kD prolamins increases recombinant protein yield and recovery rate in rice endosperm

artículo científico publicado en 2012

Rice SPK, a calmodulin-like domain protein kinase, is required for storage product accumulation during seed development: phosphorylation of sucrose synthase is a possible factor

artículo científico publicado en 2002

Rice seed ER-derived protein body as an efficient delivery vehicle for oral tolerogenic peptides

artículo científico publicado en 2010

Rice seed for delivery of vaccines to gut mucosal immune tissues

artículo científico

Rice-based mucosal vaccine as a global strategy for cold-chain- and needle-free vaccination

artículo científico publicado en 2007

Roles of isoamylase and ADP-glucose pyrophosphorylase in starch granule synthesis in rice endosperm

artículo científico publicado en 2005

Safety and efficacy of rice seed-based oral allergy vaccine for Japanese cedar pollinosis in Japanese monkeys

artículo científico publicado en 2020

Secretory IgA-mediated protection against V. cholerae and heat-labile enterotoxin-producing enterotoxigenic Escherichia coli by rice-based vaccine

artículo científico publicado en 2010

Secretory type of recombinant thioredoxin h induces ER stress in endosperm cells of transgenic rice

artículo científico publicado en 2012

Seed-based oral vaccines as allergen-specific immunotherapies

artículo científico publicado el 1 de marzo de 2011

Seed-specific expression of truncated OsGAD2 produces GABA-enriched rice grains that influence a decrease in blood pressure in spontaneously hypertensive rats

artículo científico publicado en 2009

Signal transduction by IRE1-mediated splicing of bZIP50 and other stress sensors in the endoplasmic reticulum stress response of rice

scientific article published on 12 December 2011

Specific region affects the difference in accumulation levels between apple food allergen Mal d 1 and birch pollen allergen Bet v 1 which are expressed in vegetative tissues of transgenic rice

article

Sporophytic ovule tissues modulate the initiation and progression of apomixis in Hieracium

artículo científico publicado en 2012

Suppression of GPI-induced arthritis by oral administration of transgenic rice seeds expressing altered peptide ligands

artículo científico publicado en 2017

Suppression of collagen-induced arthritis by oral administration of transgenic rice seeds expressing altered peptide ligands of type II collagen

artículo científico publicado en 2014

Suppression of glucose-6-phosphate-isomerase induced arthritis by oral administration of transgenic rice seeds expressing altered peptide ligands of glucose-6-phosphate-isomerase

artículo científico publicado en 2016

Synergism between RPBF Dof and RISBZ1 bZIP activators in the regulation of rice seed expression genes

artículo científico publicado en 2006

T-cell activation by transgenic rice seeds expressing the genetically modified Japanese cedar pollen allergens

scientific article published on 23 August 2019

The 3'-untranslated region of rice glutelin GluB-1 affects accumulation of heterologous protein in transgenic rice

artículo científico publicado en 2009

The correlation between expression and localization of a foreign gene product in rice endosperm

artículo científico publicado en 2006

The critical role of disulfide bond formation in protein sorting in the endosperm of rice

artículo científico publicado en 2005

The hypocholesterolemic activity of transgenic rice seed accumulating lactostatin, a bioactive peptide derived from bovine milk β-lactoglobulin

artículo científico publicado en 2011

The plant-uniquecis-element that mediates signaling from multiple endoplasmic reticulum stress sensors

artículo científico publicado el 21 de marzo de 2013

The use of rice seeds to produce human pharmaceuticals for oral therapy

artículo científico

Transgene-independent heredity of RdDM-mediated transcriptional gene silencing of endogenous genes in rice.

artículo científico publicado en 2018

Transgenic rice accumulating modified cedar pollen allergen Cry j 2 derivatives

artículo científico publicado el 4 de noviembre de 2011

Transgenic rice is a source of iron for iron-depleted rats

artículo científico publicado en 2002

Transgenic rice seed expressing flavonoid biosynthetic genes accumulate glycosylated and/or acylated flavonoids in protein bodies

artículo científico publicado en 2015

Transgenic rice seed synthesizing diverse flavonoids at high levels: a new platform for flavonoid production with associated health benefits

scientific article published on 03 April 2013

Transgenic rice seeds accumulating recombinant hypoallergenic birch pollen allergen Bet v 1 generate giant protein bodies

artículo científico publicado en 2013

Transgenic rice seeds expressing altered peptide ligands against the M3 muscarinic acetylcholine receptor suppress experimental sialadenitis-like Sjögren's syndrome

artículo científico publicado en 2019

Update on the Use of Transgenic Rice Seeds in Oral Immunotherapy

artículo científico publicado el 1 de marzo de 2013

Use of a callus-specific selection system to develop transgenic rice seed accumulating a high level of recombinant protein

artículo científico publicado en 2012

Vaccination with transgenic rice seed expressing mite allergen: a new option for asthma sufferers?

artículo científico publicado en 2011

Visualization of endoplasmic reticulum stressed cells for forward genetic studies in plants

artículo científico publicado en 2015

{alpha}' Subunit of soybean {beta}-conglycinin forms complex with rice glutelin via a disulphide bond in transgenic rice seeds

artículo científico publicado en 2009