Filtros de búsqueda

Lista de obras de

Activation of Vinyl Iodides for the Highly Enantioselective Addition to Aldehydes

artículo científico publicado el 7 de febrero de 2011

Acyl dihydropyrazolo[1,5-a]pyrimidinones as metabotropic glutamate receptor 5 positive allosteric modulators

artículo científico publicado en 2015

Discovery and SAR of a novel series of metabotropic glutamate receptor 5 positive allosteric modulators with high ligand efficiency

artículo científico publicado en 2014

Evaluation of 1,2,3-Triazoles as Amide Bioisosteres In Cystic Fibrosis Transmembrane Conductance Regulator Modulators VX-770 and VX-809

scientific article published on 11 February 2019

Exploration of allosteric agonism structure-activity relationships within an acetylene series of metabotropic glutamate receptor 5 (mGlu5) positive allosteric modulators (PAMs): discovery of 5-((3-fluorophenyl)ethynyl)-N-(3-methyloxetan-3-yl)picolin

artículo científico publicado en 2013

From Highly Enantioselective Catalytic Reaction of 1,3-Diynes with Aldehydes to Facile Asymmetric Synthesis of Polycyclic Compounds

artículo científico publicado el 11 de julio de 2011

Heterotropic activation of the midazolam hydroxylase activity of CYP3A by a positive allosteric modulator of mGlu5: in vitro to in vivo translation and potential impact on clinically relevant drug-drug interactions

artículo científico publicado en 2013

Reverse the Diastereoselectivity of the Rh(I)-Catalyzed Pauson-Khand Cycloaddition

artículo científico publicado el 18 de julio de 2011

Study of the Fluorescent Properties of Partially Hydrogenated 1,1′-Bi-2-naphthol-amine Molecules and Their Use for Enantioselective Fluorescent Recognition

artículo científico publicado el 24 de marzo de 2011

Targeting selective activation of M(1) for the treatment of Alzheimer's disease: further chemical optimization and pharmacological characterization of the M(1) positive allosteric modulator ML169.

artículo científico publicado en 2012

Tetrahydronaphthyridine and dihydronaphthyridinone ethers as positive allosteric modulators of the metabotropic glutamate receptor 5 (mGlu₅).

artículo científico publicado en 2014

Total Synthesis of Stemaphylline N‐Oxide and Related C9a‐Epimeric Analogues

artículo científico publicado el 16 de agosto de 2013