Lista de obras -

A Comparative Study of the Structural Dynamics of Four Terminal Uridylyl Transferases

artículo científico publicado en 2017

APOBEC3B Nuclear Localization Requires two Distinct N-Terminal Domain Surfaces

artículo científico publicado en 2018

APOBEC3H Subcellular Localization Determinants Define Zipcode for Targeting HIV-1 for Restriction

scholarly article by Daniel J Salamango published in December 2018

Active site plasticity and possible modes of chemical inhibition of the human DNA deaminase APOBEC3B

scholarly article published 7 January 2019

Active site plasticity and possible modes of chemical inhibition of the human DNA deaminase APOBEC3B

artículo científico publicado en 2019

Adapting AlphaLISA high throughput screen to discover a novel small-molecule inhibitor targeting protein arginine methyltransferase 5 in pancreatic and colorectal cancers.

artículo científico

An integrated view of p53 dynamics, function, and reactivation

scientific article published on 02 January 2021

Computational identification of a transiently open L1/S3 pocket for reactivation of mutant p53

artículo científico publicado en 2013

Computer-aided discovery of Trypanosoma brucei RNA-editing terminal uridylyl transferase 2 inhibitors

artículo científico publicado en 2014

Conformational Switch Regulates the DNA Cytosine Deaminase Activity of Human APOBEC3B.

artículo científico publicado en 2017

Designing novel inhibitors of Trypanosoma brucei

artículo científico publicado en 2013

Determinants of Oligonucleotide Selectivity of APOBEC3B

scientific article published on 10 September 2018

Development of an AlphaLISA high throughput technique to screen for small molecule inhibitors targeting protein arginine methyltransferases.

artículo científico publicado en 2017

Dynamics and Molecular Mechanisms of p53 Transcriptional Activation

article

Elements of nucleotide specificity in the Trypanosoma brucei mitochondrial RNA editing enzyme RET2.

artículo científico publicado en 2012

Ensemble Docking in Drug Discovery

artículo científico publicado en 2018

Ensemble-based computational approach discriminates functional activity of p53 cancer and rescue mutants

artículo científico publicado en 2011

Functional and Structural Insights into a Vif/PPP2R5 Complex Elucidated using Patient HIV-1 Isolates and Computational Modeling

artículo científico publicado en 2020

Modulation of catalytic function by differential plasticity of the active site: case study of Trypanosoma cruzi trans-sialidase and Trypanosoma rangeli sialidase

artículo científico publicado en 2009

Molecular docking to flexible targets

artículo científico publicado en 2015

Neolymphostin A is a Covalent Phosphoinositide-3-kinase (PI3-K)/Mammalian Target of Rapamycin (mTOR) Dual Inhibitor that Employs an Unusual Electrophilic Vinylogous Ester

artículo científico publicado en 2018

Progress towards automated Kepler scientific workflows for computer-aided drug discovery and molecular simulations

artículo científico publicado en 2014

RNA Editing TUTase 1: structural foundation of substrate recognition, complex interactions and drug targeting

artículo científico publicado en 2016

Structural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B.

artículo científico publicado en 2016

Structure and dynamics of SARS-CoV-2 proofreading exoribonuclease ExoN

artículo científico publicado en 2022

The Binding Interface between Human APOBEC3F and HIV-1 Vif Elucidated by Genetic and Computational Approaches

artículo científico publicado en 2015

The local dinucleotide preference of APOBEC3G can be altered from 5'-CC to 5'-TC by a single amino acid substitution.

artículo científico publicado en 2013

The substrate-binding cap of the UDP-diacylglucosamine pyrophosphatase LpxH is highly flexible, enabling facile substrate binding and product release.

artículo científico publicado en 2018

Variable ligand- and receptor-binding hot spots in key strains of influenza neuraminidase

artículo científico publicado en 2012

Lista de obras de

A Comparative Study of the Structural Dynamics of Four Terminal Uridylyl Transferases

APOBEC3B Nuclear Localization Requires two Distinct N-Terminal Domain Surfaces

APOBEC3H Subcellular Localization Determinants Define Zipcode for Targeting HIV-1 for Restriction

Active site plasticity and possible modes of chemical inhibition of the human DNA deaminase APOBEC3B

Active site plasticity and possible modes of chemical inhibition of the human DNA deaminase APOBEC3B

Adapting AlphaLISA high throughput screen to discover a novel small-molecule inhibitor targeting protein arginine methyltransferase 5 in pancreatic and colorectal cancers.

An integrated view of p53 dynamics, function, and reactivation

Computational identification of a transiently open L1/S3 pocket for reactivation of mutant p53

Computer-aided discovery of Trypanosoma brucei RNA-editing terminal uridylyl transferase 2 inhibitors

Conformational Switch Regulates the DNA Cytosine Deaminase Activity of Human APOBEC3B.

Designing novel inhibitors of Trypanosoma brucei

Determinants of Oligonucleotide Selectivity of APOBEC3B

Development of an AlphaLISA high throughput technique to screen for small molecule inhibitors targeting protein arginine methyltransferases.

Dynamics and Molecular Mechanisms of p53 Transcriptional Activation

Elements of nucleotide specificity in the Trypanosoma brucei mitochondrial RNA editing enzyme RET2.

Ensemble Docking in Drug Discovery

Ensemble-based computational approach discriminates functional activity of p53 cancer and rescue mutants

Functional and Structural Insights into a Vif/PPP2R5 Complex Elucidated using Patient HIV-1 Isolates and Computational Modeling

Modulation of catalytic function by differential plasticity of the active site: case study of Trypanosoma cruzi trans-sialidase and Trypanosoma rangeli sialidase

Molecular docking to flexible targets

Neolymphostin A is a Covalent Phosphoinositide-3-kinase (PI3-K)/Mammalian Target of Rapamycin (mTOR) Dual Inhibitor that Employs an Unusual Electrophilic Vinylogous Ester

Progress towards automated Kepler scientific workflows for computer-aided drug discovery and molecular simulations

RNA Editing TUTase 1: structural foundation of substrate recognition, complex interactions and drug targeting

Structural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B.

Structure and dynamics of SARS-CoV-2 proofreading exoribonuclease ExoN

Structure and dynamics of SARS-CoV-2 proofreading exoribonuclease ExoN

The Binding Interface between Human APOBEC3F and HIV-1 Vif Elucidated by Genetic and Computational Approaches

The local dinucleotide preference of APOBEC3G can be altered from 5'-CC to 5'-TC by a single amino acid substitution.

The substrate-binding cap of the UDP-diacylglucosamine pyrophosphatase LpxH is highly flexible, enabling facile substrate binding and product release.

Variable ligand- and receptor-binding hot spots in key strains of influenza neuraminidase