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3-Mercaptopyruvate sulfurtransferase supports endothelial cell angiogenesis and bioenergetics

artículo científico publicado en 2019

ARGININE VASOPRESSIN RECEPTOR 2 ACTIVATION PROMOTES MICROVASCULAR PERMEABILITY IN SEPSIS

artículo científico publicado en 2020

Adenosine and inosine exert cytoprotective effects in an in vitro model of liver ischemia-reperfusion injury

artículo científico publicado en 2012

Cardioprotective effects of hydrogen sulfide

artículo científico publicado en 2010

Cell-based screening identifies paroxetine as an inhibitor of diabetic endothelial dysfunction

artículo científico publicado en 2012

Cellular bioenergetics is regulated by PARP1 under resting conditions and during oxidative stress

artículo científico publicado el 16 de diciembre de 2011

Cystathionine-beta-synthase inhibition for colon cancer: Enhancement of the efficacy of aminooxyacetic acid via the prodrug approach.

artículo científico publicado en 2016

Cystathionine-γ-lyase (CSE) deficiency increases erythropoiesis and promotes mitochondrial electron transport via the upregulation of coproporphyrinogen III oxidase and consequent stimulation of heme biosynthesis

artículo científico publicado en 2019

Cytoprotective effect of γ-tocopherol against tumor necrosis factor α induced cell dysfunction in L929 cells

artículo científico publicado en 2011

Cytoprotective effects of adenosine and inosine in an in vitro model of acute tubular necrosis

artículo científico publicado en 2009

Development of a stretch-induced neurotrauma model for medium-throughput screening in vitro: identification of rifampicin as a neuroprotectant.

artículo científico publicado en 2016

Effect of S-adenosyl-L-methionine (SAM), an allosteric activator of cystathionine-β-synthase (CBS) on colorectal cancer cell proliferation and bioenergetics in vitro

artículo científico publicado en 2014

Effects of 7-ketocholesterol on the activity of endothelial poly(ADP-ribose) polymerase and on endothelium-dependent relaxant function

artículo científico publicado en 2006

Endothelial dysfunction is a potential contributor to multiple organ failure and mortality in aged mice subjected to septic shock: preclinical studies in a murine model of cecal ligation and puncture

artículo científico publicado en 2014

H2S-induced S-sulfhydration of lactate dehydrogenase a (LDHA) stimulates cellular bioenergetics in HCT116 colon cancer cells

artículo científico publicado en 2017

Human internal thoracic artery grafts exhibit severe morphological and functional damage and spasmic vasomotion due to oxidative stress

artículo científico publicado el 1 de julio de 2011

Hydrogen sulfide and nitric oxide are mutually dependent in the regulation of angiogenesis and endothelium-dependent vasorelaxation

artículo científico publicado en 2012

Hydrogen sulfide replacement therapy protects the vascular endothelium in hyperglycemia by preserving mitochondrial function

artículo científico publicado en 2011

Hydrogen sulfide-mediated stimulation of mitochondrial electron transport involves inhibition of the mitochondrial phosphodiesterase 2A, elevation of cAMP and activation of protein kinase A

scientific journal article

Identification of agents that reduce renal hypoxia-reoxygenation injury using cell-based screening: purine nucleosides are alternative energy sources in LLC-PK1 cells during hypoxia

artículo científico publicado en 2011

Identification of pharmacological modulators of HMGB1-induced inflammatory response by cell-based screening

artículo científico publicado en 2013

Intramitochondrial hydrogen sulfide production by 3-mercaptopyruvate sulfurtransferase maintains mitochondrial electron flow and supports cellular bioenergetics

artículo científico publicado en 2012

Oxidant-induced cardiomyocyte injury: identification of the cytoprotective effect of a dopamine 1 receptor agonist using a cell-based high-throughput assay.

artículo científico publicado en 2007

Oxidative stress suppresses the cellular bioenergetic effect of the 3-mercaptopyruvate sulfurtransferase/hydrogen sulfide pathway

artículo científico publicado en 2013

Pathophysiological roles of peroxynitrite in circulatory shock

artículo científico publicado en 2010

Reduction of liver ischemia-reperfusion injury via glutamine pretreatment

artículo científico publicado en 2009

Regulation of Vascular Tone, Angiogenesis and Cellular Bioenergetics by the 3-Mercaptopyruvate Sulfurtransferase/H2S Pathway: Functional Impairment by Hyperglycemia and Restoration by DL-α-Lipoic Acid.

artículo científico publicado en 2015

Regulation of mitochondrial bioenergetic function by hydrogen sulfide. Part I. Biochemical and physiological mechanisms

scientific article published on April 2014

Regulation of mitochondrial bioenergetic function by hydrogen sulfide. Part II. Pathophysiological and therapeutic aspects

artículo científico publicado en 2014

Role of endogenous and exogenous nitric oxide, carbon monoxide and hydrogen sulfide in HCT116 colon cancer cell proliferation

artículo científico publicado en 2017

S-Sulfhydration of ATP synthase by hydrogen sulfide stimulates mitochondrial bioenergetics

artículo científico publicado en 2016

Screening of a composite library of clinically used drugs and well-characterized pharmacological compounds for cystathionine β-synthase inhibition identifies benserazide as a drug potentially suitable for repurposing for the experimental therapy of

scientific article published on 10 August 2016

Stimulatory effect of CSE-generated H2S on hepatic mitochondrial biogenesis and the underlying mechanisms

artículo científico publicado en 2016

Tumor-derived hydrogen sulfide, produced by cystathionine-β-synthase, stimulates bioenergetics, cell proliferation, and angiogenesis in colon cancer

artículo científico publicado en 2013

Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis.

artículo científico publicado en 2017