Lista de obras -

A High-Content Screen Identifies TPP1 and Aurora B as Regulators of Axonal Mitochondrial Transport

artículo científico publicado en 2019

A perspective on stem cell modeling of amyotrophic lateral sclerosis

artículo científico publicado en 2015

ALS-implicated protein TDP-43 sustains levels of STMN2, a mediator of motor neuron growth and repair

scientific article published on 14 January 2019

Abnormal gene expression in cloned mice derived from embryonic stem cell and cumulus cell nuclei

artículo científico publicado en 2002

Absence of Survival and Motor Deficits in 500 Repeat C9ORF72 BAC Mice

artículo científico publicado en 2020

All-Optical Electrophysiology for High-Throughput Functional Characterization of a Human iPSC-Derived Motor Neuron Model of ALS.

artículo científico publicado en 2018

C9orf72 suppresses systemic and neural inflammation induced by gut bacteria

artículo científico publicado en 2020

CAT7 and cat7l Long Non-coding RNAs Tune Polycomb Repressive Complex 1 Function during Human and Zebrafish Development

artículo científico publicado en 2016

CLP1 links tRNA metabolism to progressive motor-neuron loss

artículo científico publicado en 2013

Comparative genomic analysis of embryonic, lineage-converted, and stem cell-derived motor neurons

artículo científico publicado en 2018

Comparison of three congruent patient-specific cell types for the modelling of a human genetic Schwann-cell disorder

artículo científico publicado en 2019

Comprehensive Protocols for CRISPR/Cas9-based Gene Editing in Human Pluripotent Stem Cells

artículo científico publicado en 2016

Constructing and Deconstructing Stem Cell Models of Neurological Disease ⬇️

artículo científico publicado el 26 de mayo de 2011

Conversion of mouse and human fibroblasts into functional spinal motor neurons

artículo científico publicado en 2011

Derivation of embryonic germ cells and male gametes from embryonic stem cells

artículo científico publicado en 2003

Developmental reprogramming after chromosome transfer into mitotic mouse zygotes

artículo científico publicado en 2007

Digital RNA allelotyping reveals tissue-specific and allele-specific gene expression in human

artículo científico publicado en 2009

Dipeptide repeat proteins activate a heat shock response found in C9ORF72-ALS/FTLD patients.

artículo científico publicado en 2018

Directed differentiation and functional maturation of cortical interneurons from human embryonic stem cells

artículo científico publicado en 2013

Dnmt1 overexpression causes genomic hypermethylation, loss of imprinting, and embryonic lethality

artículo científico publicado en 2002

Dysregulated protocadherin-pathway activity as an intrinsic defect in induced pluripotent stem cell-derived cortical interneurons from subjects with schizophrenia

artículo científico publicado en 2019

Effect of Ezogabine on Cortical and Spinal Motor Neuron Excitability in Amyotrophic Lateral Sclerosis: A Randomized Clinical Trial

artículo científico publicado en 2020

Efficient CRISPR-Cas9-mediated generation of knockin human pluripotent stem cells lacking undesired mutations at the targeted locus

artículo científico publicado en 2015

Exome sequencing in amyotrophic lateral sclerosis implicates a novel gene, DNAJC7, encoding a heat-shock protein

scientific article published on 25 November 2019

FUS is sequestered in nuclear aggregates in ALS patient fibroblasts

artículo científico publicado en 2014

Flp recombinase regulated lacZ expression at the ROSA26 locus

artículo científico publicado en 2002

From Dish to Bedside: Lessons Learned While Translating Findings from a Stem Cell Model of Disease to a Clinical Trial

artículo científico publicado en 2015

Generation of a Motor Nerve Organoid with Human Stem Cell-Derived Neurons

artículo científico publicado en 2017

Generation of neuropeptidergic hypothalamic neurons from human pluripotent stem cells

artículo científico publicado en 2015

Genetic validation of a therapeutic target in a mouse model of ALS.

artículo científico publicado en 2014

Genoppi is an open-source software for robust and standardized integration of proteomic and genetic data

artículo científico publicado en 2021

How to make spinal motor neurons

artículo científico publicado en 2014

Human embryonic stem cell-derived motor neurons are sensitive to the toxic effect of glial cells carrying an ALS-causing mutation

artículo científico publicado en 2008

Impracticality of Egg Donor Recruitment in the Absence of Compensation ⬇️

artículo científico publicado el 4 de octubre de 2011

Incomplete reactivation of Oct4-related genes in mouse embryos cloned from somatic nuclei

artículo científico publicado en 2003

Intrinsic membrane hyperexcitability of amyotrophic lateral sclerosis patient-derived motor neurons

artículo científico publicado en 2014

Loss-of-function mutations in the C9ORF72 mouse ortholog cause fatal autoimmune disease

artículo científico publicado en 2016

Male and female mice derived from the same embryonic stem cell clone by tetraploid embryo complementation

artículo científico publicado en 2002

Mediators of reprogramming: transcription factors and transitions through mitosis

artículo científico publicado en 2008

Mice cloned from olfactory sensory neurons

artículo científico publicado en 2004

Micromanipulating dosage compensation: understanding X-chromosome inactivation through nuclear transplantation

artículo científico publicado en 2003

Modeling human disease with pluripotent stem cells: from genome association to function.

artículo científico publicado en 2013

Molecularly cleavable bioinks facilitate high-performance digital light processing-based bioprinting of functional volumetric soft tissues

artículo científico publicado en 2022

Monitoring peripheral nerve degeneration in ALS by label-free stimulated Raman scattering imaging

artículo científico publicado en 2016

Nanog-independent reprogramming to iPSCs with canonical factors

artículo científico publicado en 2014

Nuclear Cloning, Epigenetic Reprogramming and Cellular Differentiation

Nuclear cloning, epigenetic reprogramming and cellular differentiation.

artículo científico publicado en 2005

Nuclear cloning, stem cells, and genomic reprogramming

artículo científico publicado en 2002

Opportunities and challenges of pluripotent stem cell neurodegenerative disease models

artículo científico publicado en 2013

Optimal timing of inner cell mass isolation increases the efficiency of human embryonic stem cell derivation and allows generation of sibling cell lines

artículo científico publicado en 2009

Pathways disrupted in human ALS motor neurons identified through genetic correction of mutant SOD1.

artículo científico publicado en 2014

Progress toward the clinical application of patient-specific pluripotent stem cells

artículo científico publicado en 2010

Publisher Correction: Exome sequencing in amyotrophic lateral sclerosis implicates a novel gene, DNAJC7, encoding a heat-shock protein

artículo científico publicado en 2020

Recipient cell nuclear factors are required for reprogramming by nuclear transfer

artículo científico publicado en 2010

Reprogramming within hours following nuclear transfer into mouse but not human zygotes ⬇️

artículo científico publicado el 4 de octubre de 2011

SLC52A3, A Brown-Vialetto-van Laere syndrome candidate gene is essential for mouse development, but dispensable for motor neuron differentiation

artículo científico publicado en 2016

Shushing down the epigenetic landscape towards stem cell differentiation

artículo científico publicado en 2010

Somatic coding mutations in human induced pluripotent stem cells

artículo científico publicado en 2011

Targeted bisulfite sequencing reveals changes in DNA methylation associated with nuclear reprogramming

artículo científico publicado en 2009

The C9orf72-interacting protein Smcr8 is a negative regulator of autoimmunity and lysosomal exocytosis

artículo científico publicado en 2018

The mouse C9ORF72 ortholog is enriched in neurons known to degenerate in ALS and FTD.

artículo científico publicado en 2013

The role of maternal-specific H3K9me3 modification in establishing imprinted X-chromosome inactivation and embryogenesis in mice

artículo científico publicado en 2014

Two familial ALS proteins function in prevention/repair of transcription-associated DNA damage

artículo científico publicado en 2016

Lista de obras de

A High-Content Screen Identifies TPP1 and Aurora B as Regulators of Axonal Mitochondrial Transport

A perspective on stem cell modeling of amyotrophic lateral sclerosis

ALS-implicated protein TDP-43 sustains levels of STMN2, a mediator of motor neuron growth and repair

Abnormal gene expression in cloned mice derived from embryonic stem cell and cumulus cell nuclei

Absence of Survival and Motor Deficits in 500 Repeat C9ORF72 BAC Mice

All-Optical Electrophysiology for High-Throughput Functional Characterization of a Human iPSC-Derived Motor Neuron Model of ALS.

C9orf72 suppresses systemic and neural inflammation induced by gut bacteria

CAT7 and cat7l Long Non-coding RNAs Tune Polycomb Repressive Complex 1 Function during Human and Zebrafish Development

CLP1 links tRNA metabolism to progressive motor-neuron loss

Comparative genomic analysis of embryonic, lineage-converted, and stem cell-derived motor neurons

Comparison of three congruent patient-specific cell types for the modelling of a human genetic Schwann-cell disorder

Comprehensive Protocols for CRISPR/Cas9-based Gene Editing in Human Pluripotent Stem Cells

Constructing and Deconstructing Stem Cell Models of Neurological Disease ⬇️

Conversion of mouse and human fibroblasts into functional spinal motor neurons

Derivation of embryonic germ cells and male gametes from embryonic stem cells

Developmental reprogramming after chromosome transfer into mitotic mouse zygotes

Digital RNA allelotyping reveals tissue-specific and allele-specific gene expression in human

Dipeptide repeat proteins activate a heat shock response found in C9ORF72-ALS/FTLD patients.

Directed differentiation and functional maturation of cortical interneurons from human embryonic stem cells

Dnmt1 overexpression causes genomic hypermethylation, loss of imprinting, and embryonic lethality

Dysregulated protocadherin-pathway activity as an intrinsic defect in induced pluripotent stem cell-derived cortical interneurons from subjects with schizophrenia

Effect of Ezogabine on Cortical and Spinal Motor Neuron Excitability in Amyotrophic Lateral Sclerosis: A Randomized Clinical Trial

Efficient CRISPR-Cas9-mediated generation of knockin human pluripotent stem cells lacking undesired mutations at the targeted locus

Exome sequencing in amyotrophic lateral sclerosis implicates a novel gene, DNAJC7, encoding a heat-shock protein

FUS is sequestered in nuclear aggregates in ALS patient fibroblasts

Flp recombinase regulated lacZ expression at the ROSA26 locus

From Dish to Bedside: Lessons Learned While Translating Findings from a Stem Cell Model of Disease to a Clinical Trial

Generation of a Motor Nerve Organoid with Human Stem Cell-Derived Neurons

Generation of neuropeptidergic hypothalamic neurons from human pluripotent stem cells

Genetic validation of a therapeutic target in a mouse model of ALS.

Genoppi is an open-source software for robust and standardized integration of proteomic and genetic data

How to make spinal motor neurons

Human embryonic stem cell-derived motor neurons are sensitive to the toxic effect of glial cells carrying an ALS-causing mutation

Impracticality of Egg Donor Recruitment in the Absence of Compensation ⬇️

Incomplete reactivation of Oct4-related genes in mouse embryos cloned from somatic nuclei

Intrinsic membrane hyperexcitability of amyotrophic lateral sclerosis patient-derived motor neurons

Loss-of-function mutations in the C9ORF72 mouse ortholog cause fatal autoimmune disease

Male and female mice derived from the same embryonic stem cell clone by tetraploid embryo complementation

Mediators of reprogramming: transcription factors and transitions through mitosis

Mice cloned from olfactory sensory neurons

Micromanipulating dosage compensation: understanding X-chromosome inactivation through nuclear transplantation

Modeling human disease with pluripotent stem cells: from genome association to function.

Molecularly cleavable bioinks facilitate high-performance digital light processing-based bioprinting of functional volumetric soft tissues

Monitoring peripheral nerve degeneration in ALS by label-free stimulated Raman scattering imaging

Nanog-independent reprogramming to iPSCs with canonical factors

Nuclear Cloning, Epigenetic Reprogramming and Cellular Differentiation

Nuclear cloning, epigenetic reprogramming and cellular differentiation.

Nuclear cloning, stem cells, and genomic reprogramming

Opportunities and challenges of pluripotent stem cell neurodegenerative disease models

Optimal timing of inner cell mass isolation increases the efficiency of human embryonic stem cell derivation and allows generation of sibling cell lines

Pathways disrupted in human ALS motor neurons identified through genetic correction of mutant SOD1.

Progress toward the clinical application of patient-specific pluripotent stem cells

Publisher Correction: Exome sequencing in amyotrophic lateral sclerosis implicates a novel gene, DNAJC7, encoding a heat-shock protein

Recipient cell nuclear factors are required for reprogramming by nuclear transfer

Reprogramming within hours following nuclear transfer into mouse but not human zygotes ⬇️

SLC52A3, A Brown-Vialetto-van Laere syndrome candidate gene is essential for mouse development, but dispensable for motor neuron differentiation

Shushing down the epigenetic landscape towards stem cell differentiation

Somatic coding mutations in human induced pluripotent stem cells

Targeted bisulfite sequencing reveals changes in DNA methylation associated with nuclear reprogramming

The C9orf72-interacting protein Smcr8 is a negative regulator of autoimmunity and lysosomal exocytosis

The mouse C9ORF72 ortholog is enriched in neurons known to degenerate in ALS and FTD.

The role of maternal-specific H3K9me3 modification in establishing imprinted X-chromosome inactivation and embryogenesis in mice

Two familial ALS proteins function in prevention/repair of transcription-associated DNA damage