Lista de obras -

( R )-2-Hydroxyglutarate Is Sufficient to Promote Leukemogenesis and Its Effects Are Reversible ⬇️

artículo científico publicado el 7 de febrero de 2013

A decade of progress in myelodysplastic syndrome with chromosome 5q deletion

artículo científico publicado en 2018

A dominant-negative effect drives selection of TP53 missense mutations in myeloid malignancies

scientific article published on 01 August 2019

A germline JAK2 SNP is associated with predisposition to the development of JAK2(V617F)-positive myeloproliferative neoplasms

artículo científico publicado en 2009

Age-related clonal hematopoiesis associated with adverse outcomes

artículo científico publicado en 2014

Calmodulin inhibitors improve erythropoiesis in Diamond-Blackfan anemia

artículo científico publicado en 2020

Cancer therapy shapes the fitness landscape of clonal hematopoiesis

artículo científico publicado en 2020

Clinical effect of point mutations in myelodysplastic syndromes

artículo científico publicado en 2011

Clonal hematopoiesis in human aging and disease

scientific article published on 01 November 2019

Clonal hematopoiesis is associated with adverse outcomes in multiple myeloma patients undergoing transplant

artículo científico publicado en 2020

Coordinate loss of a microRNA and protein-coding gene cooperate in the pathogenesis of 5q− syndrome ⬇️

artículo científico publicado el 26 de agosto de 2011

Defining the human C2H2 zinc finger degrome targeted by thalidomide analogs through CRBN

artículo científico publicado en 2018

Diamond Blackfan Anemia and Ribosome Biogenesis: Introduction ⬇️

artículo científico publicado el 1 de abril de 2011

Diminutive somatic deletions in the 5q region lead to a phenotype atypical of classical 5q− syndrome ⬇️

artículo científico publicado el 13 de agosto de 2013

Distinct roles for long-term hematopoietic stem cells and erythroid precursor cells in a murine model of Jak2V617F-mediated polycythemia vera ⬇️

artículo científico publicado el 24 de mayo de 2012

Distinction of lymphoid and myeloid clonal hematopoiesis

artículo científico publicado en 2021

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

artículo científico publicado en 2005

Generations of physician-scientists

artículo científico publicado en 2018

Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies

artículo científico publicado en 2009

Hematopoietic mosaic chromosomal alterations and risk for infection among 767,891 individuals without blood cancer

scientific article published on 16 November 2020

Hematopoietic mosaic chromosomal alterations increase the risk for diverse types of infection

Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes

artículo científico publicado en 2020

Increased neutrophil extracellular trap formation promotes thrombosis in myeloproliferative neoplasms.

artículo científico publicado en 2018

Inherited causes of clonal haematopoiesis in 97,691 whole genomes

artículo científico publicado en 2020

Janus Reveals Another Face: The Biologic Rationale for Targeting Janus Kinase 2 in Lymphoma ⬇️

artículo científico publicado el 10 de septiembre de 2012

Metagene projection for cross-platform, cross-species characterization of global transcriptional states

artículo científico publicado en 2007

Myeloproliferative Neoplasm Animal Models ⬇️

artículo científico publicado el 21 de agosto de 2012

NRAS mutations with low allele burden have independent prognostic significance for patients with lower risk myelodysplastic syndromes ⬇️

artículo científico publicado el 27 de mayo de 2013

Novel approaches to the treatment of sickle cell disease: the potential of histone deacetylase inhibitors ⬇️

artículo científico publicado el 1 de junio de 2012

PPM1D mutations are oncogenic drivers of de novo diffuse midline glioma formation

artículo científico publicado en 2022

Pulmonary Fibrosis, Bone Marrow Failure, and Telomerase Mutation ⬇️

artículo científico publicado el 19 de abril de 2012

Rapid and deep-scale ubiquitylation profiling for biology and translational research

artículo científico publicado en 2020

Recurrent genetic HLA loss in AML relapsed after matched unrelated allogeneic hematopoietic cell transplantation

scientific article published on 01 July 2019

Regulation of Transcription by Hypoxia Requires a Multiprotein Complex That Includes Hypoxia-Inducible Factor 1, an Adjacent Transcription Factor, and p300/CREB Binding Protein ⬇️

artículo científico publicado el 1 de julio de 1998

Reversible ON- and OFF-switch chimeric antigen receptors controlled by lenalidomide

artículo científico publicado en 2021

Ribosome defects in disorders of erythropoiesis ⬇️

artículo científico publicado el 1 de febrero de 2011

SF3B1-mutant myelodysplastic syndrome as a distinct disease subtype - A Proposal of the International Working Group for the Prognosis of Myelodysplastic Syndromes (IWG-PM)

artículo científico publicado en 2020

STATistical Power of Clonal Analysis: Differential STAT1 Pathway Activation Downstream of the JAK2V617F Mutation ⬇️

artículo científico publicado el 16 de noviembre de 2010

Sinister Symbiosis: Pathological Hematopoietic-Stromal Interactions in CML ⬇️

artículo científico publicado el 5 de septiembre de 2013

Small-molecule-induced polymerization triggers degradation of BCL6

artículo científico publicado en 2020

Stress granules contribute to α-globin homeostasis in differentiating erythroid cells ⬇️

artículo científico publicado el 20 de marzo de 2012

TET2 mutations predict response to hypomethylating agents in myelodysplastic syndrome patients

artículo científico publicado en 2014

TP53 mutation status divides myelodysplastic syndromes with complex karyotypes into distinct prognostic subgroups

scientific article published on 11 January 2019

The AIM2 inflammasome exacerbates atherosclerosis in clonal haematopoiesis

scientific article published on 17 March 2021

The CDK inhibitor CR8 acts as a molecular glue degrader that depletes cyclin K

scientific article published on 03 June 2020

The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice

artículo científico publicado en 2016

The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice

artículo científico publicado en 2016

The STAT5 inhibitor pimozide decreases survival of chronic myelogenous leukemia cells resistant to kinase inhibitors ⬇️

artículo científico publicado el 13 de enero de 2011

The emerging importance of ribosomal dysfunction in the pathogenesis of hematologic disorders ⬇️

artículo científico publicado el 28 de agosto de 2013

The impact of the COVID-19 pandemic on cancer care

scientific article published on 20 May 2020

The landscape of somatic copy-number alteration across human cancers

artículo científico publicado en 2010

Translational medicine: ribosomopathies ⬇️

artículo científico publicado el 20 de octubre de 2011

Unraveling the Molecular Pathophysiology of Myelodysplastic Syndromes ⬇️

artículo científico publicado el 10 de enero de 2011

Validation of a prognostic model and the impact of mutations in patients with lower-risk myelodysplastic syndromes

artículo científico publicado en 2012

miR-126 Regulates Distinct Self-Renewal Outcomes in Normal and Malignant Hematopoietic Stem Cells

artículo científico publicado en 2016

miR-126 Regulates Distinct Self-Renewal Outcomes in Normal and Malignant Hematopoietic Stem Cells.

artículo científico publicado en 2016

miR-433 is aberrantly expressed in myeloproliferative neoplasms and suppresses hematopoietic cell growth and differentiation ⬇️

artículo científico publicado el 6 de agosto de 2012

Lista de obras de

( R )-2-Hydroxyglutarate Is Sufficient to Promote Leukemogenesis and Its Effects Are Reversible ⬇️

A decade of progress in myelodysplastic syndrome with chromosome 5q deletion

A dominant-negative effect drives selection of TP53 missense mutations in myeloid malignancies

A germline JAK2 SNP is associated with predisposition to the development of JAK2(V617F)-positive myeloproliferative neoplasms

Age-related clonal hematopoiesis associated with adverse outcomes

Calmodulin inhibitors improve erythropoiesis in Diamond-Blackfan anemia

Cancer therapy shapes the fitness landscape of clonal hematopoiesis

Clinical effect of point mutations in myelodysplastic syndromes

Clonal hematopoiesis in human aging and disease

Clonal hematopoiesis is associated with adverse outcomes in multiple myeloma patients undergoing transplant

Coordinate loss of a microRNA and protein-coding gene cooperate in the pathogenesis of 5q− syndrome ⬇️

Defining the human C2H2 zinc finger degrome targeted by thalidomide analogs through CRBN

Diamond Blackfan Anemia and Ribosome Biogenesis: Introduction ⬇️

Diminutive somatic deletions in the 5q region lead to a phenotype atypical of classical 5q− syndrome ⬇️

Distinct roles for long-term hematopoietic stem cells and erythroid precursor cells in a murine model of Jak2V617F-mediated polycythemia vera ⬇️

Distinction of lymphoid and myeloid clonal hematopoiesis

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

Generations of physician-scientists

Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies

Hematopoietic mosaic chromosomal alterations and risk for infection among 767,891 individuals without blood cancer

Hematopoietic mosaic chromosomal alterations increase the risk for diverse types of infection

Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes

Increased neutrophil extracellular trap formation promotes thrombosis in myeloproliferative neoplasms.

Inherited causes of clonal haematopoiesis in 97,691 whole genomes

Janus Reveals Another Face: The Biologic Rationale for Targeting Janus Kinase 2 in Lymphoma ⬇️

Metagene projection for cross-platform, cross-species characterization of global transcriptional states

Myeloproliferative Neoplasm Animal Models ⬇️

NRAS mutations with low allele burden have independent prognostic significance for patients with lower risk myelodysplastic syndromes ⬇️

Novel approaches to the treatment of sickle cell disease: the potential of histone deacetylase inhibitors ⬇️

PPM1D mutations are oncogenic drivers of de novo diffuse midline glioma formation

Pulmonary Fibrosis, Bone Marrow Failure, and Telomerase Mutation ⬇️

Rapid and deep-scale ubiquitylation profiling for biology and translational research

Recurrent genetic HLA loss in AML relapsed after matched unrelated allogeneic hematopoietic cell transplantation

Regulation of Transcription by Hypoxia Requires a Multiprotein Complex That Includes Hypoxia-Inducible Factor 1, an Adjacent Transcription Factor, and p300/CREB Binding Protein ⬇️

Reversible ON- and OFF-switch chimeric antigen receptors controlled by lenalidomide

Ribosome defects in disorders of erythropoiesis ⬇️

SF3B1-mutant myelodysplastic syndrome as a distinct disease subtype - A Proposal of the International Working Group for the Prognosis of Myelodysplastic Syndromes (IWG-PM)

STATistical Power of Clonal Analysis: Differential STAT1 Pathway Activation Downstream of the JAK2V617F Mutation ⬇️

Sinister Symbiosis: Pathological Hematopoietic-Stromal Interactions in CML ⬇️

Small-molecule-induced polymerization triggers degradation of BCL6

Stress granules contribute to α-globin homeostasis in differentiating erythroid cells ⬇️

TET2 mutations predict response to hypomethylating agents in myelodysplastic syndrome patients

TP53 mutation status divides myelodysplastic syndromes with complex karyotypes into distinct prognostic subgroups

The AIM2 inflammasome exacerbates atherosclerosis in clonal haematopoiesis

The CDK inhibitor CR8 acts as a molecular glue degrader that depletes cyclin K

The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice

The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice

The STAT5 inhibitor pimozide decreases survival of chronic myelogenous leukemia cells resistant to kinase inhibitors ⬇️

The emerging importance of ribosomal dysfunction in the pathogenesis of hematologic disorders ⬇️

The impact of the COVID-19 pandemic on cancer care

The landscape of somatic copy-number alteration across human cancers

Translational medicine: ribosomopathies ⬇️

Unraveling the Molecular Pathophysiology of Myelodysplastic Syndromes ⬇️

Validation of a prognostic model and the impact of mutations in patients with lower-risk myelodysplastic syndromes

miR-126 Regulates Distinct Self-Renewal Outcomes in Normal and Malignant Hematopoietic Stem Cells

miR-126 Regulates Distinct Self-Renewal Outcomes in Normal and Malignant Hematopoietic Stem Cells.

miR-433 is aberrantly expressed in myeloproliferative neoplasms and suppresses hematopoietic cell growth and differentiation ⬇️