Lista de obras -

20-Aminosteroids as a novel class of selective and complete androgen receptor antagonists and inhibitors of prostate cancer cell growth

artículo científico publicado en 2010

A designed cell-permeable aptamer-based corepressor peptide is highly specific for the androgen receptor and inhibits prostate cancer cell growth in a vector-free mode.

artículo científico publicado en 2011

A natural androgen receptor antagonist induces cellular senescence in prostate cancer cells

artículo científico publicado en 2014

A novel crosstalk between the tumor suppressors ING1 and ING2 regulates androgen receptor signaling

artículo científico publicado en 2016

A reciprocal feedback between the PDZ binding kinase and androgen receptor drives prostate cancer

artículo científico publicado en 2018

Activity-guided isolation of an antiandrogenic compound of Pygeum africanum

artículo científico publicado en 2006

Agonist-antagonist induced coactivator and corepressor interplay on the human androgen receptor.

artículo científico publicado en 2003

Alien inhibits E2F1 gene expression and cell proliferation.

artículo científico publicado en 2007

Alien interacts with the human androgen receptor and inhibits prostate cancer cell growth

artículo científico

Alien/CSN2 gene expression is regulated by thyroid hormone in rat brain

scientific journal article

Analysis of Ligand-Specific Co-repressor Binding to the Androgen Receptor ⬇️

artículo científico publicado el 1 de enero de 2011

Antiandrogenic activity of anthranilic acid ester derivatives as novel lead structures to inhibit prostate cancer cell proliferation ⬇️

artículo científico publicado el 27 de abril de 2011

BCR-ABL- and Ras-independent activation of Raf as a novel mechanism of Imatinib resistance in CML.

artículo científico publicado en 2011

Bag-1M inhibits the transactivation of the glucocorticoid receptor via recruitment of corepressors.

artículo científico publicado en 2009

Bag-1M is a component of the in vivo DNA-glucocorticoid receptor complex at hormone-regulated promoter

artículo científico publicado en 2008

Chaperones for proper androgen action - a plethora of assistance to androgen receptor function

artículo científico publicado en 2012

Choline Kinase Alpha as an Androgen Receptor Chaperone and Prostate Cancer Therapeutic Target

artículo científico publicado en 2015

Computational and functional analysis of the androgen receptor antagonist atraric acid and its derivatives

artículo científico publicado en 2013

Computationally identified novel diphenyl- and phenylpyridine androgen receptor antagonist structures

artículo científico publicado en 2008

Detection and identification of transcription factors as interaction partners of alien in vivo

artículo científico publicado en 2007

Docosahexaenoic acid inhibits the growth of hormone-dependent prostate cancer cells by promoting the degradation of the androgen receptor

artículo científico publicado en 2015

Extracts from Pygeum africanum and other ethnobotanical species with antiandrogenic activity

artículo científico publicado en 2006

Gene regulation by thyroid hormone receptors

artículo científico publicado en 2002

Gene repression by nuclear hormone receptors

artículo científico publicado en 2004

Gene silencing by the thyroid hormone receptor

artículo científico publicado en 2003

Growth inhibition by the tumor suppressor p33ING1 in immortalized and primary cells: involvement of two silencing domains and effect of Ras.

artículo científico publicado en 2005

Halogen-substituted anthranilic acid derivatives provide a novel chemical platform for androgen receptor antagonists

artículo científico publicado en 2019

ING2 recruits histone methyltransferase activity with methylation site specificity distinct from histone H3 lysines 4 and 9.

artículo científico publicado en 2008

Inhibition of MAPK-signaling pathway promotes the interaction of the corepressor SMRT with the human androgen receptor and mediates repression of prostate cancer cell growth in the presence of antiandrogens

artículo científico publicado en 2009

Interference with the androgen receptor protein stability in therapy-resistant prostate cancer

artículo científico publicado en 2018

Interleukin-23 Represses the Level of Cell Senescence Induced by the Androgen Receptor Antagonists Enzalutamide and Darolutamide in Castration-Resistant Prostate Cancer Cells

scientific article published on 20 June 2020

Ligand-dependent Corepressor Acts as a Novel Androgen Receptor Corepressor, Inhibits Prostate Cancer Growth, and Is Functionally Inactivated by the Src Protein Kinase ⬇️

artículo científico publicado el 19 de agosto de 2011

Mechanisms of Androgen Receptor Agonist- and Antagonist-Mediated Cellular Senescence in Prostate Cancer

scientific article published on 08 July 2020

Mixed lineage kinase 2 enhances trans-repression of Alien and nuclear receptors

artículo científico publicado en 2003

NBBS isolated from Pygeum africanum bark exhibits androgen antagonistic activity, inhibits AR nuclear translocation and prostate cancer cell growth. ⬇️

artículo científico publicado en 2009

Novel Nor-Homo- and Spiro-Oxetan- Steroids Target the Human Androgen Receptor and Act as Antiandrogens

artículo científico publicado en 2014

Protein-protein cross-linking in the use of the eukaryotic eGST-fusion system.

artículo científico publicado en 2002

Regulation of the anaphase-promoting complex by the COP9 signalosome

artículo científico publicado en 2009

Sex Differences in Diabetes- and TGF-β1-Induced Renal Damage

scientific article published on 03 October 2020

Sodium butyrate induces cellular senescence in neuroblastoma and prostate cancer cells

artículo científico publicado en 2011

Supraphysiological androgen levels induce cellular senescence in human prostate cancer cells through the Src-Akt pathway

artículo científico publicado en 2014

Synthetic lethality between androgen receptor signalling and the PARP pathway in prostate cancer

artículo científico

The ING tumor suppressors in cellular senescence and chromatin ⬇️

artículo científico publicado el 18 de julio de 2011

The activation of OR51E1 causes growth suppression of human prostate cancer cells

artículo científico publicado en 2016

The amino terminus of the human AR is target for corepressor action and antihormone agonism

artículo científico publicado en 2002

The coregulator Alien

artículo científico publicado en 2007

The corepressor activity of Alien is controlled by CREB-binding protein/p300

artículo científico publicado en 2013

The highly conserved region of the co-repressor Sin3A functionally interacts with the co-repressor Alien

artículo científico publicado en 2004

The natural compound atraric acid is an antagonist of the human androgen receptor inhibiting cellular invasiveness and prostate cancer cell growth

artículo científico publicado en 2009

The natural compound atraric acid suppresses androgen-regulated neo-angiogenesis of castration-resistant prostate cancer through angiopoietin 2

scientific article published on 05 May 2022

The natural compounds atraric acid and N-butylbenzene-sulfonamide as antagonists of the human androgen receptor and inhibitors of prostate cancer cell growth ⬇️

artículo científico publicado el 19 de octubre de 2010

The nucleosome assembly activity of NAP1 is enhanced by Alien

artículo científico publicado en 2007

The tumor suppressor ING1b is a novel corepressor for the androgen receptor and induces cellular senescence in prostate cancer cells

artículo científico publicado en 2016

The tumor suppressors p33ING1 and p33ING2 interact with alien in vivo and enhance alien-mediated gene silencing.

artículo científico publicado en 2007

Thyroid hormone induces cellular senescence in prostate cancer cells through induction of DEC1

artículo científico publicado en 2020

VDR‐Alien: a novel, DNA‐selective vitamin D<sub>3</sub>receptor‐corepressor partnership

artículo científico publicado en 2000

Various members of the E2F transcription factor family interact in vivo with the corepressor alien.

artículo científico publicado en 2007

Wild-type but not mutant androgen receptor inhibits expression of the hTERT telomerase subunit: a novel role of AR mutation for prostate cancer development

artículo científico publicado en 2007

Lista de obras de

20-Aminosteroids as a novel class of selective and complete androgen receptor antagonists and inhibitors of prostate cancer cell growth

A designed cell-permeable aptamer-based corepressor peptide is highly specific for the androgen receptor and inhibits prostate cancer cell growth in a vector-free mode.

A natural androgen receptor antagonist induces cellular senescence in prostate cancer cells

A novel crosstalk between the tumor suppressors ING1 and ING2 regulates androgen receptor signaling

A reciprocal feedback between the PDZ binding kinase and androgen receptor drives prostate cancer

Activity-guided isolation of an antiandrogenic compound of Pygeum africanum

Agonist-antagonist induced coactivator and corepressor interplay on the human androgen receptor.

Alien inhibits E2F1 gene expression and cell proliferation.

Alien interacts with the human androgen receptor and inhibits prostate cancer cell growth

Alien/CSN2 gene expression is regulated by thyroid hormone in rat brain

Analysis of Ligand-Specific Co-repressor Binding to the Androgen Receptor ⬇️

Antiandrogenic activity of anthranilic acid ester derivatives as novel lead structures to inhibit prostate cancer cell proliferation ⬇️

BCR-ABL- and Ras-independent activation of Raf as a novel mechanism of Imatinib resistance in CML.

Bag-1M inhibits the transactivation of the glucocorticoid receptor via recruitment of corepressors.

Bag-1M is a component of the in vivo DNA-glucocorticoid receptor complex at hormone-regulated promoter

Chaperones for proper androgen action - a plethora of assistance to androgen receptor function

Choline Kinase Alpha as an Androgen Receptor Chaperone and Prostate Cancer Therapeutic Target

Computational and functional analysis of the androgen receptor antagonist atraric acid and its derivatives

Computationally identified novel diphenyl- and phenylpyridine androgen receptor antagonist structures

Detection and identification of transcription factors as interaction partners of alien in vivo

Docosahexaenoic acid inhibits the growth of hormone-dependent prostate cancer cells by promoting the degradation of the androgen receptor

Extracts from Pygeum africanum and other ethnobotanical species with antiandrogenic activity

Gene regulation by thyroid hormone receptors

Gene repression by nuclear hormone receptors

Gene silencing by the thyroid hormone receptor

Growth inhibition by the tumor suppressor p33ING1 in immortalized and primary cells: involvement of two silencing domains and effect of Ras.

Halogen-substituted anthranilic acid derivatives provide a novel chemical platform for androgen receptor antagonists

ING2 recruits histone methyltransferase activity with methylation site specificity distinct from histone H3 lysines 4 and 9.

Inhibition of MAPK-signaling pathway promotes the interaction of the corepressor SMRT with the human androgen receptor and mediates repression of prostate cancer cell growth in the presence of antiandrogens

Interference with the androgen receptor protein stability in therapy-resistant prostate cancer

Interleukin-23 Represses the Level of Cell Senescence Induced by the Androgen Receptor Antagonists Enzalutamide and Darolutamide in Castration-Resistant Prostate Cancer Cells

Ligand-dependent Corepressor Acts as a Novel Androgen Receptor Corepressor, Inhibits Prostate Cancer Growth, and Is Functionally Inactivated by the Src Protein Kinase ⬇️

Mechanisms of Androgen Receptor Agonist- and Antagonist-Mediated Cellular Senescence in Prostate Cancer

Mixed lineage kinase 2 enhances trans-repression of Alien and nuclear receptors

NBBS isolated from Pygeum africanum bark exhibits androgen antagonistic activity, inhibits AR nuclear translocation and prostate cancer cell growth. ⬇️

Novel Nor-Homo- and Spiro-Oxetan- Steroids Target the Human Androgen Receptor and Act as Antiandrogens

Protein-protein cross-linking in the use of the eukaryotic eGST-fusion system.

Regulation of the anaphase-promoting complex by the COP9 signalosome

Sex Differences in Diabetes- and TGF-β1-Induced Renal Damage

Sodium butyrate induces cellular senescence in neuroblastoma and prostate cancer cells

Supraphysiological androgen levels induce cellular senescence in human prostate cancer cells through the Src-Akt pathway

Synthetic lethality between androgen receptor signalling and the PARP pathway in prostate cancer

The ING tumor suppressors in cellular senescence and chromatin ⬇️

The activation of OR51E1 causes growth suppression of human prostate cancer cells

The amino terminus of the human AR is target for corepressor action and antihormone agonism

The coregulator Alien

The corepressor activity of Alien is controlled by CREB-binding protein/p300

The highly conserved region of the co-repressor Sin3A functionally interacts with the co-repressor Alien

The natural compound atraric acid is an antagonist of the human androgen receptor inhibiting cellular invasiveness and prostate cancer cell growth

The natural compound atraric acid suppresses androgen-regulated neo-angiogenesis of castration-resistant prostate cancer through angiopoietin 2

The natural compounds atraric acid and N-butylbenzene-sulfonamide as antagonists of the human androgen receptor and inhibitors of prostate cancer cell growth ⬇️

The nucleosome assembly activity of NAP1 is enhanced by Alien

The tumor suppressor ING1b is a novel corepressor for the androgen receptor and induces cellular senescence in prostate cancer cells

The tumor suppressors p33ING1 and p33ING2 interact with alien in vivo and enhance alien-mediated gene silencing.

Thyroid hormone induces cellular senescence in prostate cancer cells through induction of DEC1

VDR‐Alien: a novel, DNA‐selective vitamin D<sub>3</sub>receptor‐corepressor partnership

Various members of the E2F transcription factor family interact in vivo with the corepressor alien.

Wild-type but not mutant androgen receptor inhibits expression of the hTERT telomerase subunit: a novel role of AR mutation for prostate cancer development