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A Novel Phenotype Links HIV-1 Capsid Stability to cGAS-Mediated DNA Sensing

scientific article published on 30 July 2019

An improved labeling strategy enables automated detection of single-virus fusion and assessment of HIV-1 protease activity in single virions

artículo científico publicado en 2017

Anionic lipids are required for vesicular stomatitis virus G protein-mediated single particle fusion with supported lipid bilayers

artículo científico publicado en 2013

Can HIV-1 entry sites be deduced by comparing bulk endocytosis to functional readouts for viral fusion?

artículo científico publicado en 2015

Click labeling of unnatural sugars metabolically incorporated into viral envelope glycoproteins enables visualization of single particle fusion

artículo científico publicado en 2016

Common principles and intermediates of viral protein-mediated fusion: the HIV-1 paradigm

scientific article published on 10 December 2008

Correlated fluorescence microscopy and cryo-electron tomography of virus-infected or transfected mammalian cells

artículo científico publicado en 2016

Distinct requirements for HIV-cell fusion and HIV-mediated cell-cell fusion.

artículo científico publicado en 2015

Driving a wedge between viral lipids blocks infection

artículo científico publicado el 27 de septiembre de 2010

Early steps of HIV-1 fusion define the sensitivity to inhibitory peptides that block 6-helix bundle formation

artículo científico publicado en 2009

Exploring Modifications of an HIV-1 Capsid Inhibitor: Design, Synthesis, and Mechanism of Action

article

Facile autofluorescence suppression enabling tracking of single viruses in live cells

scientific article published on 06 November 2019

Fluorescent protein-tagged Vpr dissociates from HIV-1 core after viral fusion and rapidly enters the cell nucleus

artículo científico publicado en 2015

Fusion Stage of HIV-1 Entry Depends on Virus-Induced Cell Surface Exposure of Phosphatidylserine

artículo científico publicado en 2017

Fusion of mature HIV-1 particles leads to complete release of a gag-GFP-based content marker and raises the intraviral pH

artículo científico publicado en 2013

HIV enters cells via endocytosis and dynamin-dependent fusion with endosomes

artículo científico publicado en 2009

HIV entry: a game of hide-and-fuse?

artículo científico publicado en 2014

HIV-1 Fusion with CD4+ T cells Is Promoted by Proteins Involved in Endocytosis and Intracellular Membrane Trafficking

article

HIV-1 Uncoating and Nuclear Import Precede the Completion of Reverse Transcription in Cell Lines and in Primary Macrophages

artículo científico publicado en 2020

HIV-1 integrase tetramers are the antiviral target of pyridine-based allosteric integrase inhibitors.

artículo científico publicado en 2019

HIV-1 replication complexes accumulate in nuclear speckles and integrate into speckle-associated genomic domains

artículo científico publicado en 2020

Hepatitis C virus is primed by CD81 protein for low pH-dependent fusion

artículo científico publicado en 2011

High-Throughput HIV-Cell Fusion Assay for Discovery of Virus Entry Inhibitors

artículo científico publicado en 2015

How entry inhibitors synergize to fight HIV.

artículo científico publicado en 2017

IFITM3 restricts influenza A virus entry by blocking the formation of fusion pores following virus-endosome hemifusion

artículo científico publicado en 2014

Imaging Single Retrovirus Entry through Alternative Receptor Isoforms and Intermediates of Virus-Endosome Fusion

artículo científico publicado el 20 de enero de 2011

Imaging individual retroviral fusion events: from hemifusion to pore formation and growth

artículo científico publicado en 2005

Induction of Cell-Cell Fusion by Ebola Virus Glycoprotein: Low pH Is Not a Trigger

artículo científico publicado en 2016

Inhibition of HIV-1 endocytosis allows lipid mixing at the plasma membrane, but not complete fusion.

artículo científico publicado en 2011

Inhibition of human immunodeficiency virus type 1 entry in cells expressing gp41-derived peptides

artículo científico publicado en 2004

Intercellular Adhesion Molecule 1 Promotes HIV-1 Attachment but Not Fusion to Target Cells

artículo científico publicado el 6 de septiembre de 2012

Interferon-Induced Transmembrane Protein 3 Blocks Fusion of Diverse Enveloped Viruses by Altering Mechanical Properties of Cell Membranes

artículo científico publicado en 2021

Interferon-Induced Transmembrane Protein 3 Blocks Fusion of Diverse Enveloped Viruses by Locally Altering Mechanical Properties of Cell Membranes

artículo científico publicado en 2020

Interferon-induced transmembrane protein 3 blocks fusion of sensitive but not resistant viruses by partitioning into virus-carrying endosomes

artículo científico publicado en 2019

Live-Cell Imaging of Early Steps of Single HIV-1 Infection

artículo científico publicado en 2018

Localization and functions of native and eGFP-tagged capsid proteins in HIV-1 particles

artículo científico publicado en 2022

Membrane Fusion Mediated by Human Immunodeficiency Virus Envelope Glycoprotein

artículo científico publicado el 1 de enero de 2011

Membrane-anchored inhibitory peptides capture human immunodeficiency virus type 1 gp41 conformations that engage the target membrane prior to fusion

artículo científico publicado en 2006

Multifaceted mechanisms of HIV-1 entry inhibition by human α-defensin

artículo científico publicado en 2012

P2X1 Receptor Antagonists Inhibit HIV-1 Fusion by Blocking Virus-Coreceptor Interactions

artículo científico publicado en 2015

Pinpointing retrovirus entry sites in cells expressing alternatively spliced receptor isoforms by single virus imaging

artículo científico publicado en 2014

Publisher Correction: HIV-1 replication complexes accumulate in nuclear speckles and integrate into speckle-associated genomic domains

artículo científico publicado en 2020

Quantitative imaging of endosome acidification and single retrovirus fusion with distinct pools of early endosomes

artículo científico publicado en 2012

Rapamycin reduces CCR5 density levels on CD4 T cells, and this effect results in potentiation of enfuvirtide (T-20) against R5 strains of human immunodeficiency virus type 1 in vitro

artículo científico publicado en 2007

Reduction of CCR5 with low-dose rapamycin enhances the antiviral activity of vicriviroc against both sensitive and drug-resistant HIV-1.

scholarly article

SERINC5 protein inhibits HIV-1 fusion pore formation by promoting functional inactivation of envelope glycoproteins.

artículo científico publicado en 2017

Screening and Functional Profiling of Small-Molecule HIV-1 Entry and Fusion Inhibitors

artículo científico publicado en 2017

Sec24C is an HIV-1 host dependency factor crucial for virus replication

artículo científico publicado en 2021

Siglec-1 initiates formation of the virus-containing compartment and enhances macrophage-to-T cell transmission of HIV-1.

artículo científico publicado en 2017

Single HIV-1 Imaging Reveals Progression of Infection through CA-Dependent Steps of Docking at the Nuclear Pore, Uncoating, and Nuclear Transport

article

Structural and mechanistic bases for a potent HIV-1 capsid inhibitor

artículo científico publicado en 2020

Sub-Inhibitory Concentrations of Human α-defensin Potentiate Neutralizing Antibodies against HIV-1 gp41 Pre-Hairpin Intermediates in the Presence of Serum

artículo científico publicado el 13 de junio de 2013

Super-Resolution Fluorescence Imaging Reveals That Serine Incorporator Protein 5 Inhibits Human Immunodeficiency Virus Fusion by Disrupting Envelope Glycoprotein Clusters

scientific article published on 22 May 2020

Synchronized retrovirus fusion in cells expressing alternative receptor isoforms releases the viral core into distinct sub-cellular compartments

artículo científico publicado en 2012

Ternary complex formation of human immunodeficiency virus type 1 Env, CD4, and chemokine receptor captured as an intermediate of membrane fusion

artículo científico publicado en 2005

The role of the N-terminal segment of CCR5 in HIV-1 Env-mediated membrane fusion and the mechanism of virus adaptation to CCR5 lacking this segment

artículo científico publicado en 2007

Time-Resolved Imaging of Single HIV-1 Uncoating In Vitro and in Living Cells

artículo científico publicado en 2016

Visualization of Content Release from Cell Surface-Attached Single HIV-1 Particles Carrying an Extra-Viral Fluorescent pH-Sensor

artículo científico publicado en 2016

Visualization of retrovirus uptake and delivery into acidic endosomes

artículo científico publicado el 15 de marzo de 2011

pH regulation in early endosomes and interferon-inducible transmembrane proteins control avian retrovirus fusion

artículo científico publicado en 2017