Lista de obras -

2017 Update of ESC/EAS Task Force on practical clinical guidance for proprotein convertase subtilisin/kexin type 9 inhibition in patients with atherosclerotic cardiovascular disease or in familial hypercholesterolaemia

artículo científico publicado en 2017

A novel apoA-I mutation (L178P) leads to endothelial dysfunction, increased arterial wall thickness, and premature coronary artery disease

artículo científico publicado en 2004

Adrenal Function in females with low plasma HDL-C due to mutations in ABCA1 and LCAT.

artículo científico publicado en 2014

Antisense oligonucleotides targeting apolipoprotein(a) in people with raised lipoprotein(a): two randomised, double-blind, placebo-controlled, dose-ranging trials

artículo científico publicado en 2016

Apolipoprotein A-II is inversely associated with risk of future coronary artery disease

artículo científico publicado en 2007

Apolipoprotein C-III Levels and Incident Coronary Artery Disease Risk: The EPIC-Norfolk Prospective Population Study

artículo científico publicado en 2017

Arterial and Cellular Inflammation in Patients with CKD.

artículo científico publicado en 2016

Atherosclerotic plaque targeting mechanism of long-circulating nanoparticles established by multimodal imaging

artículo científico publicado en 2015

Author Correction: Efficacy and safety assessment of a TRAF6-targeted nanoimmunotherapy in atherosclerotic mice and non-human primates

artículo científico publicado en 2018

Biologic effects of simvastatin in patients with aneurysmal subarachnoid hemorrhage: a double-blind, placebo-controlled randomized trial.

artículo científico publicado en 2009

Both paraoxonase-1 genotype and activity do not predict the risk of future coronary artery disease; the EPIC-Norfolk Prospective Population Study

artículo científico publicado en 2009

CCR2 expression on circulating monocytes is associated with arterial wall inflammation assessed by 18F-FDG PET/CT in patients at risk for cardiovascular disease

artículo científico publicado en 2017

CETP expression reverses the reconstituted HDL-induced increase in VLDL.

artículo científico publicado en 2011

Carotid arterial wall inflammation in peripheral artery disease is augmented by type 2 diabetes: a cross-sectional study

artículo científico publicado en 2016

Carriers of loss-of-function mutations in ABCA1 display pancreatic beta-cell dysfunction

artículo científico publicado en 2010

Carriers of loss-of-function mutations in EXT display impaired pancreatic beta-cell reserve due to smaller pancreas volume

artículo científico publicado en 2014

Changes in lipids and lipoprotein particle concentrations after interruption of antiretroviral therapy.

artículo científico publicado en 2010

Chemokine ligand 2 genetic variants, serum monocyte chemoattractant protein-1 levels, and the risk of coronary artery disease

artículo científico publicado en 2010

Consistent LDL-C response with evolocumab among patient subgroups in PROFICIO: A pooled analysis of 3146 patients from phase 3 studies

scientific article published on 21 October 2018

Current therapies for lowering lipoprotein (a)

artículo científico publicado en 2016

Effect of anti-ApoA-I antibody-coating of stents on neointima formation in a rabbit balloon-injury model

artículo científico publicado en 2015

Effect of apolipoprotein-B synthesis inhibition on liver triglyceride content in patients with familial hypercholesterolemia

artículo científico publicado en 2009

Effect of open-label infusion of an apoA-I-containing particle (CER-001) on RCT and artery wall thickness in patients with FHA

artículo científico publicado en 2015

Effects of an antisense oligonucleotide inhibitor of C-reactive protein synthesis on the endotoxin challenge response in healthy human male volunteers

artículo científico publicado en 2014

Efficacy and safety assessment of a TRAF6-targeted nanoimmunotherapy in atherosclerotic mice and non-human primates

artículo científico publicado en 2018

Efficacy and safety of alirocumab in reducing lipids and cardiovascular events

artículo científico publicado en 2015

Efficacy and safety of high-density lipoprotein cholesterol-increasing compounds: a meta-analysis of randomized controlled trials

artículo científico publicado en 2005

Elevated Lp(a) (Lipoprotein[a]) Levels Increase Risk of 30-Day Major Adverse Cardiovascular Events in Patients Following Carotid Endarterectomy

artículo científico publicado en 2020

Endothelial Surface Layer Degradation by Chronic Hyaluronidase Infusion Induces Proteinuria in Apolipoprotein E-Deficient Mice ⬇️

artículo científico publicado el 8 de diciembre de 2010

Erratum to: Unexpected arterial wall and cellular inflammation in patients with rheumatoid arthritis in remission using biological therapy: a cross-sectional study

artículo científico publicado en 2016

Ext1 heterozygosity causes a modest effect on postprandial lipid clearance in humans

artículo científico publicado en 2015

Familial hypercholesterolaemia in children and adolescents: gaining decades of life by optimizing detection and treatment.

artículo científico publicado en 2015

Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease: consensus statement of the European Atherosclerosis Society

artículo científico publicado en 2013

Glycocalyx and endothelial (dys) function: from mice to men.

artículo científico publicado en 2006

HDL mimetic CER-001 targets atherosclerotic plaques in patients

artículo científico publicado en 2016

Hepatic and cardiovascular consequences of familial hypobetalipoproteinemia

artículo científico publicado en 2005

Heterozygosity for a loss-of-function mutation in GALNT2 improves plasma triglyceride clearance in man.

artículo científico publicado en 2011

High prevalence of mutations in LCAT in patients with low HDL cholesterol levels in The Netherlands: identification and characterization of eight novel mutations

artículo científico publicado en 2011

High-density lipoprotein cholesterol, high-density lipoprotein particle size, and apolipoprotein A-I: significance for cardiovascular risk: the IDEAL and EPIC-Norfolk studies

artículo científico publicado en 2008

Homozygous familial hypercholesterolaemia: new insights and guidance for clinicians to improve detection and clinical management. A position paper from the Consensus Panel on Familial Hypercholesterolaemia of the European Atherosclerosis Society

artículo científico publicado en 2014

How common are foot problems among individuals with diabetes? Diabetic foot ulcers in the Dutch population

artículo científico publicado en 2017

Hypercoagulability in the metabolic syndrome.

artículo científico publicado en 2005

Hypertension is associated with marked alterations in sphingolipid biology: a potential role for ceramide

artículo científico publicado en 2011

Identification and Management of Statin-Associated Symptoms in Clinical Practice: Extension of a Clinician Survey to 12 Further Countries

artículo científico publicado en 2017

Imaging systemic inflammatory networks in ischemic heart disease

artículo científico publicado en 2015

Impact of cholesterol on proinflammatory monocyte production by the bone marrow

artículo científico publicado en 2021

Impact of oral vancomycin on gut microbiota, bile acid metabolism, and insulin sensitivity.

artículo científico publicado en 2013

In vivo cell seeding with anti-CD34 antibodies successfully accelerates endothelialization but stimulates intimal hyperplasia in porcine arteriovenous expanded polytetrafluoroethylene grafts

artículo científico publicado en 2005

In vivo tissue cholesterol efflux is reduced in carriers of a mutation in APOA1.

artículo científico publicado en 2013

Increasing the Spatial Resolution of 3T Carotid MRI Has No Beneficial Effect for Plaque Component Measurement Reproducibility

artículo científico publicado en 2015

Inhibiting macrophage proliferation suppresses atherosclerotic plaque inflammation

artículo científico publicado en 2015

Inhibition of ApoCIII: the next PCSK9?

artículo científico

Inhibition of hepatic sulfatase-2 in vivo: a novel strategy to correct diabetic dyslipidemia.

artículo científico publicado en 2012

Lipid oxidation in carriers of lecithin:cholesterol acyltransferase gene mutations

artículo científico publicado en 2012

Liver histology during Mipomersen therapy for severe hypercholesterolemia

artículo científico publicado en 2014

Local overexpression of C-type natriuretic peptide ameliorates vascular adaptation of porcine hemodialysis grafts

artículo científico publicado en 2004

Long-Term Retrospective Analysis of Gene Therapy with Alipogene Tiparvovec and Its Effect on Lipoprotein Lipase Deficiency-Induced Pancreatitis

artículo científico publicado en 2016

Magnetic Resonance Imaging-Derived Renal Oxygenation and Perfusion During Continuous, Steady-State Angiotensin-II Infusion in Healthy Humans

artículo científico publicado en 2016

Matrix metalloproteinase inhibition reduces intimal hyperplasia in a porcine arteriovenous-graft model

artículo científico publicado en 2004

Measurement of subclinical atherosclerosis: beyond risk factor assessment

artículo científico publicado en 2002

Metabolic modulation of inflammation-induced activation of coagulation

artículo científico publicado en 2008

Microthrombosis after aneurysmal subarachnoid hemorrhage: an additional explanation for delayed cerebral ischemia

artículo científico publicado en 2008

Nevirapine and efavirenz elicit different changes in lipid profiles in antiretroviral-therapy-naive patients infected with HIV-1

artículo científico publicado en 2004

New prospects for PCSK9 inhibition?

artículo científico publicado en 2018

New risk factors for atherosclerosis and patient risk assessment

artículo científico publicado en 2004

Nile Red Quantifier: a novel and quantitative tool to study lipid accumulation in patient-derived circulating monocytes using confocal microscopy.

artículo científico publicado en 2017

Noninvasive Differentiation between Hepatic Steatosis and Steatohepatitis with MR Imaging Enhanced with USPIOs in Patients with Nonalcoholic Fatty Liver Disease: A Proof-of-Concept Study

artículo científico

Nonpharmacological lipoprotein apheresis reduces arterial inflammation in familial hypercholesterolemia.

artículo científico publicado en 2014

Obesity and dyslipidemia

artículo científico publicado en 2011

Oral treatment with Eubacterium hallii improves insulin sensitivity in db/db mice.

artículo científico publicado en 2016

Oxidized Phospholipids on Lipoprotein(a) Elicit Arterial Wall Inflammation and an Inflammatory Monocyte Response in Humans ⬇️

artículo científico

PCSK9 monoclonal antibodies reverse the pro-inflammatory profile of monocytes in familial hypercholesterolaemia

artículo científico publicado en 2017

Prednisolone-containing liposomes accumulate in human atherosclerotic macrophages upon intravenous administration

artículo científico publicado en 2015

Prolonged hematopoietic and myeloid cellular response in patients after an acute coronary syndrome measured with 18F-DPA-714 PET/CT

artículo científico publicado en 2018

Reduced fecal sterol excretion in subjects with familial hypoalphalipoproteinemia.

artículo científico publicado en 2009

Remnant Cholesterol Elicits Arterial Wall Inflammation and a Multilevel Cellular Immune Response in Humans

artículo científico publicado en 2017

Role of the apolipoprotein B-apolipoprotein A-I ratio in cardiovascular risk assessment: a case-control analysis in EPIC-Norfolk

artículo científico publicado en 2007

Role of tumor necrosis factor-α in the human systemic endotoxin-induced transcriptome

artículo científico publicado en 2013

SULF2 strongly prediposes to fasting and postprandial triglycerides in patients with obesity and type 2 diabetes mellitus

artículo científico publicado en 2014

Safety and tolerability of dalcetrapib

artículo científico publicado en 2009

Serum levels of mannose-binding lectin and the risk of future coronary artery disease in apparently healthy men and women

artículo científico publicado en 2006

Serum myeloperoxidase levels are associated with the future risk of coronary artery disease in apparently healthy individuals: the EPIC-Norfolk Prospective Population Study

artículo científico publicado en 2007

Simvastatin with or without ezetimibe in familial hypercholesterolemia

artículo científico publicado en 2008

Subclinical atherosclerosis as a target of therapy: potential role of statins

artículo científico publicado en 2004

Sympathetic activation by lower body negative pressure decreases kidney perfusion without inducing hypoxia in healthy humans

artículo científico publicado en 2018

Systemic Glucocorticoids Are Associated With Mortality After Carotid Endarterectomy

artículo científico publicado en 2015

Targeted proteomics improves cardiovascular risk prediction in secondary prevention

artículo científico publicado en 2022

The effect of a diiodothyronine mimetic on insulin sensitivity in male cardiometabolic patients: a double-blind randomized controlled trial

artículo científico publicado en 2014

The gut microbiome as novel cardio-metabolic target: the time has come!

artículo científico publicado en 2013

The polygenic nature of hypertriglyceridaemia: implications for definition, diagnosis, and management

artículo científico publicado en 2013

The role of CETP inhibition in dyslipidemia

artículo científico publicado en 2007

Thresholds for Arterial Wall Inflammation Quantified by (18)F-FDG PET Imaging: Implications for Vascular Interventional Studies

artículo científico publicado en 2016

Treatment with Statins Does Not Revert Trained Immunity in Patients with Familial Hypercholesterolemia

scientific article published on 13 June 2019

Unexpected arterial wall and cellular inflammation in patients with rheumatoid arthritis in remission using biological therapy: a cross-sectional study.

artículo científico publicado en 2016

Lista de obras de

2017 Update of ESC/EAS Task Force on practical clinical guidance for proprotein convertase subtilisin/kexin type 9 inhibition in patients with atherosclerotic cardiovascular disease or in familial hypercholesterolaemia

A novel apoA-I mutation (L178P) leads to endothelial dysfunction, increased arterial wall thickness, and premature coronary artery disease

Adrenal Function in females with low plasma HDL-C due to mutations in ABCA1 and LCAT.

Antisense oligonucleotides targeting apolipoprotein(a) in people with raised lipoprotein(a): two randomised, double-blind, placebo-controlled, dose-ranging trials

Apolipoprotein A-II is inversely associated with risk of future coronary artery disease

Apolipoprotein C-III Levels and Incident Coronary Artery Disease Risk: The EPIC-Norfolk Prospective Population Study

Arterial and Cellular Inflammation in Patients with CKD.

Atherosclerotic plaque targeting mechanism of long-circulating nanoparticles established by multimodal imaging

Author Correction: Efficacy and safety assessment of a TRAF6-targeted nanoimmunotherapy in atherosclerotic mice and non-human primates

Biologic effects of simvastatin in patients with aneurysmal subarachnoid hemorrhage: a double-blind, placebo-controlled randomized trial.

Both paraoxonase-1 genotype and activity do not predict the risk of future coronary artery disease; the EPIC-Norfolk Prospective Population Study

CCR2 expression on circulating monocytes is associated with arterial wall inflammation assessed by 18F-FDG PET/CT in patients at risk for cardiovascular disease

CETP expression reverses the reconstituted HDL-induced increase in VLDL.

Carotid arterial wall inflammation in peripheral artery disease is augmented by type 2 diabetes: a cross-sectional study

Carriers of loss-of-function mutations in ABCA1 display pancreatic beta-cell dysfunction

Carriers of loss-of-function mutations in EXT display impaired pancreatic beta-cell reserve due to smaller pancreas volume

Changes in lipids and lipoprotein particle concentrations after interruption of antiretroviral therapy.

Chemokine ligand 2 genetic variants, serum monocyte chemoattractant protein-1 levels, and the risk of coronary artery disease

Consistent LDL-C response with evolocumab among patient subgroups in PROFICIO: A pooled analysis of 3146 patients from phase 3 studies

Current therapies for lowering lipoprotein (a)

Effect of anti-ApoA-I antibody-coating of stents on neointima formation in a rabbit balloon-injury model

Effect of apolipoprotein-B synthesis inhibition on liver triglyceride content in patients with familial hypercholesterolemia

Effect of open-label infusion of an apoA-I-containing particle (CER-001) on RCT and artery wall thickness in patients with FHA

Effects of an antisense oligonucleotide inhibitor of C-reactive protein synthesis on the endotoxin challenge response in healthy human male volunteers

Efficacy and safety assessment of a TRAF6-targeted nanoimmunotherapy in atherosclerotic mice and non-human primates

Efficacy and safety of alirocumab in reducing lipids and cardiovascular events

Efficacy and safety of high-density lipoprotein cholesterol-increasing compounds: a meta-analysis of randomized controlled trials

Elevated Lp(a) (Lipoprotein[a]) Levels Increase Risk of 30-Day Major Adverse Cardiovascular Events in Patients Following Carotid Endarterectomy

Endothelial Surface Layer Degradation by Chronic Hyaluronidase Infusion Induces Proteinuria in Apolipoprotein E-Deficient Mice ⬇️

Erratum to: Unexpected arterial wall and cellular inflammation in patients with rheumatoid arthritis in remission using biological therapy: a cross-sectional study

Ext1 heterozygosity causes a modest effect on postprandial lipid clearance in humans

Familial hypercholesterolaemia in children and adolescents: gaining decades of life by optimizing detection and treatment.

Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease: consensus statement of the European Atherosclerosis Society

Glycocalyx and endothelial (dys) function: from mice to men.

HDL mimetic CER-001 targets atherosclerotic plaques in patients

Hepatic and cardiovascular consequences of familial hypobetalipoproteinemia

Heterozygosity for a loss-of-function mutation in GALNT2 improves plasma triglyceride clearance in man.

High prevalence of mutations in LCAT in patients with low HDL cholesterol levels in The Netherlands: identification and characterization of eight novel mutations

High-density lipoprotein cholesterol, high-density lipoprotein particle size, and apolipoprotein A-I: significance for cardiovascular risk: the IDEAL and EPIC-Norfolk studies

Homozygous familial hypercholesterolaemia: new insights and guidance for clinicians to improve detection and clinical management. A position paper from the Consensus Panel on Familial Hypercholesterolaemia of the European Atherosclerosis Society

How common are foot problems among individuals with diabetes? Diabetic foot ulcers in the Dutch population

Hypercoagulability in the metabolic syndrome.

Hypertension is associated with marked alterations in sphingolipid biology: a potential role for ceramide

Identification and Management of Statin-Associated Symptoms in Clinical Practice: Extension of a Clinician Survey to 12 Further Countries

Imaging systemic inflammatory networks in ischemic heart disease

Impact of cholesterol on proinflammatory monocyte production by the bone marrow

Impact of oral vancomycin on gut microbiota, bile acid metabolism, and insulin sensitivity.

In vivo cell seeding with anti-CD34 antibodies successfully accelerates endothelialization but stimulates intimal hyperplasia in porcine arteriovenous expanded polytetrafluoroethylene grafts

In vivo tissue cholesterol efflux is reduced in carriers of a mutation in APOA1.

Increasing the Spatial Resolution of 3T Carotid MRI Has No Beneficial Effect for Plaque Component Measurement Reproducibility

Inhibiting macrophage proliferation suppresses atherosclerotic plaque inflammation

Inhibition of ApoCIII: the next PCSK9?

Inhibition of hepatic sulfatase-2 in vivo: a novel strategy to correct diabetic dyslipidemia.

Lipid oxidation in carriers of lecithin:cholesterol acyltransferase gene mutations

Liver histology during Mipomersen therapy for severe hypercholesterolemia

Local overexpression of C-type natriuretic peptide ameliorates vascular adaptation of porcine hemodialysis grafts

Long-Term Retrospective Analysis of Gene Therapy with Alipogene Tiparvovec and Its Effect on Lipoprotein Lipase Deficiency-Induced Pancreatitis

Magnetic Resonance Imaging-Derived Renal Oxygenation and Perfusion During Continuous, Steady-State Angiotensin-II Infusion in Healthy Humans

Matrix metalloproteinase inhibition reduces intimal hyperplasia in a porcine arteriovenous-graft model

Measurement of subclinical atherosclerosis: beyond risk factor assessment

Metabolic modulation of inflammation-induced activation of coagulation

Microthrombosis after aneurysmal subarachnoid hemorrhage: an additional explanation for delayed cerebral ischemia

Nevirapine and efavirenz elicit different changes in lipid profiles in antiretroviral-therapy-naive patients infected with HIV-1

New prospects for PCSK9 inhibition?

New risk factors for atherosclerosis and patient risk assessment

Nile Red Quantifier: a novel and quantitative tool to study lipid accumulation in patient-derived circulating monocytes using confocal microscopy.

Noninvasive Differentiation between Hepatic Steatosis and Steatohepatitis with MR Imaging Enhanced with USPIOs in Patients with Nonalcoholic Fatty Liver Disease: A Proof-of-Concept Study

Nonpharmacological lipoprotein apheresis reduces arterial inflammation in familial hypercholesterolemia.

Obesity and dyslipidemia

Oral treatment with Eubacterium hallii improves insulin sensitivity in db/db mice.

Oxidized Phospholipids on Lipoprotein(a) Elicit Arterial Wall Inflammation and an Inflammatory Monocyte Response in Humans ⬇️

PCSK9 monoclonal antibodies reverse the pro-inflammatory profile of monocytes in familial hypercholesterolaemia

Prednisolone-containing liposomes accumulate in human atherosclerotic macrophages upon intravenous administration

Prolonged hematopoietic and myeloid cellular response in patients after an acute coronary syndrome measured with 18F-DPA-714 PET/CT

Reduced fecal sterol excretion in subjects with familial hypoalphalipoproteinemia.

Remnant Cholesterol Elicits Arterial Wall Inflammation and a Multilevel Cellular Immune Response in Humans

Role of the apolipoprotein B-apolipoprotein A-I ratio in cardiovascular risk assessment: a case-control analysis in EPIC-Norfolk

Role of tumor necrosis factor-α in the human systemic endotoxin-induced transcriptome

SULF2 strongly prediposes to fasting and postprandial triglycerides in patients with obesity and type 2 diabetes mellitus