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Cell autonomous regulation of hippocampal circuitry via Aph1b-γ-secretase/neuregulin 1 signalling

artículo científico publicado en 2014

Cloning, characterization, and chromosomal localization to 4p16 of the human gene (LRPAP1) coding for the alpha 2-macroglobulin receptor-associated protein and structural comparison with the murine gene coding for the 44-kDa heparin-binding protein

artículo científico publicado en 1995

Coordinated and widespread expression of gamma-secretase in vivo: evidence for size and molecular heterogeneity

scientific journal article

Differential contribution of the three Aph1 genes to gamma-secretase activity in vivo

artículo científico publicado en 2005

Metabolic and Behavioural Phenotypes in Nestin-Cre Mice Are Caused by Hypothalamic Expression of Human Growth Hormone

artículo científico publicado en 2015

Mice lacking Dfna5 show a diverging number of cochlear fourth row outer hair cells

scientific journal article

Mitochondrial rhomboid PARL regulates cytochrome c release during apoptosis via OPA1-dependent cristae remodeling

scientific journal article

Molecular Analysis of the Human and Mouse α2M Family ⬇️

artículo científico publicado el 10 de septiembre de 1994

Presenilin 1 mediates the turnover of telencephalin in hippocampal neurons via an autophagic degradative pathway

scientific journal article

Presenilin 2 deficiency causes a mild pulmonary phenotype and no changes in amyloid precursor protein processing but enhances the embryonic lethal phenotype of presenilin 1 deficiency

scientific journal article

Presenilins form ER Ca2+ leak channels, a function disrupted by familial Alzheimer's disease-linked mutations

artículo científico publicado en 2006

Safe targeting of T cell acute lymphoblastic leukemia by pathology-specific NOTCH inhibition

artículo científico publicado en 2019

Stem-cell-derived human microglia transplanted in mouse brain to study human disease

scientific article published on 28 October 2019

Structure and Targeting in ES Cells of the Gene Coding for Mouse α2‐Macroglobulin ⬇️

artículo científico publicado el 10 de septiembre de 1994

The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for alpha-secretase activity in fibroblasts

artículo científico publicado en 2002

The disintegrin/metalloproteinase ADAM10 is essential for the establishment of the brain cortex

artículo científico publicado en 2010

β‐Secretase (BACE1) inhibition causes retinal pathology by vascular dysregulation and accumulation of age pigment ⬇️

artículo científico publicado el 20 de agosto de 2012

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