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Aberrant Lipid Metabolism Promotes Prostate Cancer: Role in Cell Survival under Hypoxia and Extracellular Vesicles Biogenesis

artículo científico publicado en 2016

Alterations in serum lipid profile patterns in oral cancer: correlation with histological grading and tobacco abuse

artículo científico

Angiopreventive efficacy of pure flavonolignans from milk thistle extract against prostate cancer: targeting VEGF-VEGFR signaling

artículo científico publicado en 2012

Anti-Cancer Efficacy of Silybin Derivatives - A Structure-Activity Relationship

artículo científico publicado el 28 de marzo de 2013

Antimetastatic efficacy of silibinin: molecular mechanisms and therapeutic potential against cancer

artículo científico publicado en 2010

Asiatic Acid Inhibits Pro-Angiogenic Effects of VEGF and Human Gliomas in Endothelial Cell Culture Models

artículo científico publicado el 3 de agosto de 2011

Asiatic acid induces endoplasmic reticulum stress and apoptotic death in glioblastoma multiforme cells both in vitro and in vivo

artículo científico publicado en 2014

Beneficial effects of the naturally occurring flavonoid silibinin on the prostate cancer microenvironment: role of monocyte chemotactic protein-1 and immune cell recruitment

artículo científico publicado en 2016

Bitter melon juice activates cellular energy sensor AMP-activated protein kinase causing apoptotic death of human pancreatic carcinoma cells

artículo científico publicado el 8 de marzo de 2013

Bitter melon juice targets molecular mechanisms underlying gemcitabine resistance in pancreatic cancer cells

artículo científico publicado en 2015

Chemopreventive efficacy of silymarin in skin and prostate cancer

artículo científico publicado en 2007

Chemopreventive opportunities to control basal cell carcinoma: Current perspectives

artículo científico

Evaluation of Specificity and Sensitivity of Oral Fluid for Diagnosis of Hepatitis B.

artículo científico

Exosome proteomic analyses identify inflammatory phenotype and novel biomarkers in African American prostate cancer patients

artículo científico publicado en 2019

Exosomes secreted by prostate cancer cells under hypoxia promote matrix metalloproteinases activity at pre-metastatic niches

scientific article published on 14 January 2020

Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules

artículo científico publicado en 2013

Generation of reactive oxygen species by grape seed extract causes irreparable DNA damage leading to G2/M arrest and apoptosis selectively in head and neck squamous cell carcinoma cells

artículo científico publicado en 2012

Grape seed extract and resveratrol prevent 4-nitroquinoline 1-oxide induced oral tumorigenesis in mice by modulating AMPK activation and associated biological responses

artículo científico publicado en 2013

Grape seed extract targets mitochondrial electron transport chain complex III and induces oxidative and metabolic stress leading to cytoprotective autophagy and apoptotic death in human head and neck cancer cells

artículo científico publicado en 2014

Graviola inhibits hypoxia-induced NADPH oxidase activity in prostate cancer cells reducing their proliferation and clonogenicity

artículo científico publicado en 2016

Hypoxia induces triglycerides accumulation in prostate cancer cells and extracellular vesicles supporting growth and invasiveness following reoxygenation

artículo científico publicado en 2015

Identifying the differential effects of silymarin constituents on cell growth and cell cycle regulatory molecules in human prostate cancer cells.

artículo científico publicado en 2008

Inhibition of Lipid Oxidation Increases Glucose Metabolism and Enhances 2-Deoxy-2-[(18)F]Fluoro-D-Glucose Uptake in Prostate Cancer Mouse Xenografts

artículo científico publicado en 2015

Interleukin-1beta-induced iNOS expression in human lung carcinoma A549 cells: involvement of STAT and MAPK pathways

artículo científico publicado el 1 de noviembre de 2011

Isosilybin A induces apoptosis in human prostate cancer cells via targeting Akt, NF-κB, and androgen receptor signaling

artículo científico publicado en 2010

Isosilybin B and isosilybin A inhibit growth, induce G1 arrest and cause apoptosis in human prostate cancer LNCaP and 22Rv1 cells.

artículo científico publicado en 2007

Kava, a tonic for relieving the irrational development of natural preventive agents

artículo científico publicado en 2008

Mass Spectrometry-Based Proteome Profiling of Extracellular Vesicles Derived from the Cerebrospinal Fluid of Adult Rhesus Monkeys Exposed to Cocaine throughout Gestation

artículo científico publicado en 2022

Metformin suppresses growth of human head and neck squamous cell carcinoma via global inhibition of protein translation

artículo científico publicado el 1 de abril de 2012

Molecular mechanisms of silibinin-mediated cancer chemoprevention with major emphasis on prostate cancer

artículo científico publicado en 2013

New combination therapies with cell-cycle agents

artículo científico publicado en 2008

Phylogenetic and chemical diversity of fungal endophytes isolated from Silybum marianum (L) Gaertn. (milk thistle)

artículo científico publicado en 2015

Procyanidin B2 3,3″-di-O-gallate inhibits endothelial cells growth and motility by targeting VEGFR2 and integrin signaling pathways

artículo científico publicado en 2015

Role of E-cadherin in Antimigratory and Antiinvasive Efficacy of Silibinin in Prostate Cancer Cells

artículo científico publicado el 5 de mayo de 2011

SNAI1 is critical for the aggressiveness of prostate cancer cells with low E-cadherin

artículo científico publicado en 2014

Silibinin Preferentially Radiosensitizes Prostate Cancer by Inhibiting DNA Repair Signaling

artículo científico publicado en 2015

Silibinin and its 2,3-dehydro-derivative inhibit basal cell carcinoma growth via suppression of mitogenic signaling and transcription factors activation.

artículo científico publicado en 2014

Silibinin enhances the repair of ultraviolet B-induced DNA damage by activating p53-dependent nucleotide excision repair mechanism in human dermal fibroblasts

artículo científico publicado en 2015

Silibinin exerts sustained growth suppressive effect against human colon carcinoma SW480 xenograft by targeting multiple signaling molecules

artículo científico publicado en 2010

Silibinin inhibits aberrant lipid metabolism, proliferation and emergence of androgen-independence in prostate cancer cells via primarily targeting the sterol response element binding protein 1.

artículo científico publicado en 2014

Silibinin inhibits cytokine-induced signaling cascades and down-regulates inducible nitric oxide synthase in human lung carcinoma A549 cells

artículo científico publicado en 2008

Silibinin inhibits fibronectin induced motility, invasiveness and survival in human prostate carcinoma PC3 cells via targeting integrin signaling

artículo científico publicado en 2014

Silibinin inhibits prostate cancer cells- and RANKL-induced osteoclastogenesis by targeting NFATc1, NF-κB, and AP-1 activation in RAW264.7 cells

scientific article published on 31 October 2012

Silibinin inhibits ultraviolet B radiation-induced DNA-damage and apoptosis by enhancing interleukin-12 expression in JB6 cells and SKH-1 hairless mouse skin

artículo científico publicado el 28 de enero de 2013

Silibinin prevents prostate cancer cell-mediated differentiation of naïve fibroblasts into cancer-associated fibroblast phenotype by targeting TGF β2.

artículo científico publicado en 2014

Silibinin prevents ultraviolet B radiation-induced epidermal damages in JB6 cells and mouse skin in a p53-GADD45α-dependent manner

artículo científico publicado el 12 de diciembre de 2011

Silibinin suppresses growth and induces apoptotic death of human colorectal carcinoma LoVo cells in culture and tumor xenograft

artículo científico publicado en 2009

Silibinin suppresses growth of human prostate carcinoma PC-3 orthotopic xenograft via activation of extracellular signal-regulated kinase 1/2 and inhibition of signal transducers and activators of transcription signaling

artículo científico publicado en 2009

Stage-specific inhibitory effects and associated mechanisms of silibinin on tumor progression and metastasis in transgenic adenocarcinoma of the mouse prostate model

artículo científico publicado en 2008

Syntaxin 6-mediated exosome secretion regulates enzalutamide resistance in prostate cancer

artículo científico publicado en 2019

Talarolutins A-D: Meroterpenoids from an endophytic fungal isolate of Talaromyces minioluteus.

artículo científico publicado en 2016

Targeting tumor microenvironment with silibinin: promise and potential for a translational cancer chemopreventive strategy

artículo científico publicado en 2013

The strategies to control prostate cancer by chemoprevention approaches

artículo científico