Lista de obras -

A novel method for evaluating antibody-dependent cell-mediated cytotoxicity by flowcytometry using cryopreserved human peripheral blood mononuclear cells

artículo científico publicado en 2016

A phase 1 study of niraparib in Japanese patients with advanced solid tumors ⬇️

artículo científico publicado en 2019

Abstract 2813: Clinical impact of immune microenvironment according to intratumoral locations of esophageal squamous cell carcinoma

scholarly article

Abstract LB-019: Anti-CD4 monoclonal antibody immunotherapy exerts an antitumor effect by replacing the T cell receptor repertoire in patients with gastrointestinal cancer

scholarly article

Anti-PD-1 antibody and anti-PD-Li antibody -from basic and clinic-

artículo científico publicado en 2017

Antibody responses against NY-ESO-1 and HER2 antigens in patients vaccinated with combinations of cholesteryl pullulan (CHP)-NY-ESO-1 and CHP-HER2 with OK-432

artículo científico publicado en 2009

Approach to the Adult Acute Lymphoblastic Leukemia Patient

artículo científico publicado en 2019

Association of CD204+ macrophages with poor outcomes of malignant lymphomas not in remission treated by allogeneic HCT

artículo científico publicado en 2019

Association of antithyroglobulin antibodies with the development of thyroid dysfunction induced by nivolumab

article

Biomarkers for Immune Checkpoint Inhibitors in Melanoma

article published in 2018

CD20+ tumor-infiltrating immune cells and CD204+ M2 macrophages are associated with prognosis in thymic carcinoma

scientific article published on 11 April 2020

CD4+ T-cell Immunity in the Peripheral Blood Correlates with Response to Anti-PD-1 Therapy

scientific article published on 23 December 2019

Chimeric Antigen Receptor T-Cells for the Treatment of B-Cell Acute Lymphoblastic Leukemia.

artículo científico publicado en 2018

Clinical Development of Immune Checkpoint Inhibitors

artículo científico publicado en 2015

Combination Therapy of Immune Checkpoint Inhibitors

artículo científico publicado en 2017

Comparison of tumor-infiltrating lymphocytes between primary and metastatic tumors in breast cancer patients

scientific article published on 11 October 2016

Complete Pathological Response to Neoadjuvant Pembrolizumab in a Patient With Chemoresistant Upper Urinary Tract Urothelial Carcinoma: A Case Report

artículo científico publicado en 2020

Comprehensive immunohistochemical analysis of tumor microenvironment immune status in esophageal squamous cell carcinoma

artículo científico publicado en 2016

Computational algorithm-driven evaluation of monocytic myeloid-derived suppressor cell frequency for prediction of clinical outcomes

artículo científico publicado en 2014

Correlation between the expression of folate receptor alpha (FRα) and clinicopathological features in patients with lung adenocarcinoma

artículo científico publicado en 2020

DNA mismatch repair deficiency in surgically resected lung adenocarcinoma: Microsatellite instability analysis using the Promega panel

artículo científico publicado en 2017

Deletion of chromosome arm 15q in a case of minimally differentiated hypoplastic AML-M0

artículo científico publicado en 2008

Determination of cellularly processed HLA-A2402-restricted novel CTL epitopes derived from two cancer germ line genes, MAGE-A4 and SAGE

artículo científico publicado en 2005

Development of immune checkpoint inhibitor in colorectal cancer

artículo científico publicado en 2016

Development of immune checkpoint inhibitors

artículo científico publicado en 2017

Diagnostic significance of intratumoral CD8+ tumor-infiltrating lymphocytes in medullary carcinoma

artículo científico publicado en 2017

Discovery of a Good Responder Subtype of Esophageal Squamous Cell Carcinoma with Cytotoxic T-Lymphocyte Signatures Activated by Chemoradiotherapy

artículo científico publicado en 2015

Do all patients in the phase I oncology trials need to be hospitalized? Domestic but outstanding issues for globalization of drug development in Japan

artículo científico publicado en 2017

Donor lymphocytes expressing the herpes simplex virus thymidine kinase suicide gene: detailed immunological function following add-back after haplo-identical transplantation

artículo científico publicado en 2015

Dose exploration results from Phase 1 study of cemiplimab, a human monoclonal programmed death (PD)-1 antibody, in Japanese patients with advanced malignancies

artículo científico publicado en 2020

Elevated fibrin-related markers in patients with malignant diseases suspected of having thrombotic disorders

artículo científico publicado en 2009

Enhancement of antitumor effect by peptide vaccine therapy in combination with anti-CD4 antibody: Study in a murine model

artículo científico publicado en 2016

Enhancement of tumor-reactive cytotoxic CD4+ T cell responses after ipilimumab treatment in four advanced melanoma patients

scientific article published on October 2013

Erratum to: Infusion of donor lymphocytes expressing the herpes simplex virus thymidine kinase suicide gene for recurrent hematologic malignancies after allogeneic hematopoietic stem cell transplantation

artículo científico publicado en 2015

Feasibility study of nivolumab as neoadjuvant chemotherapy for locally esophageal carcinoma: FRONTiER (JCOG1804E)

artículo científico publicado en 2020

First-in-human phase 1 study of IT1208, a defucosylated humanized anti-CD4 depleting antibody, in patients with advanced solid tumors

artículo científico publicado en 2019

First-in-human phase I study of E7090, a novel selective fibroblast growth factor receptor inhibitor, in patients with advanced solid tumors

artículo científico publicado en 2020

Generation of peptide-specific CD8+ T cells by phytohemagglutinin-stimulated antigen-mRNA-transduced CD4+ T cells.

artículo científico publicado en 2006

Granzyme B is a novel interleukin-18 converting enzyme.

artículo científico publicado en 2010

HER2-specific T-cell immune responses in patients vaccinated with truncated HER2 protein complexed with nanogels of cholesteryl pullulan

artículo científico publicado en 2006

High Absolute Monocyte Count Predicts Poor Clinical Outcome in Patients with Castration-Resistant Prostate Cancer Treated with Docetaxel Chemotherapy

artículo científico publicado en 2016

Histological Characteristics of Lung Adenocarcinoma with Uncommon Actionable Alterations: Special Emphasis on MET exon 14 Skipping Alterations

artículo científico publicado en 2020

Humoral immune responses in patients vaccinated with 1-146 HER2 protein complexed with cholesteryl pullulan nanogel

artículo científico publicado en 2007

Immune status at pre-treatment impacts on progression-free survival of metastatic colorectal cancer patients treated with first-line chemotherapy.

artículo científico publicado en 2015

Immunologic correlates of the abscopal effect in a patient with melanoma

artículo científico publicado en 2012

Immunotherapy for genitourinary tumors

scientific article published on 01 February 2019

Impact of low-dose anti-thymocyte globulin on immune reconstitution after allogeneic hematopoietic cell transplantation

artículo científico publicado en 2019

Improved survival among patients enrolled in oncology phase 1 trials in recent decades

scientific article published on 19 November 2019

Induction of tumoricidal function in CD4+ T cells is associated with concomitant memory and terminally differentiated phenotype

artículo científico publicado en 2012

Infection risk with PI3K-AKT-mTOR pathway inhibitors and immune checkpoint inhibitors in patients with advanced solid tumours in phase I clinical trials

artículo científico publicado en 2020

Infusion of donor lymphocytes expressing the herpes simplex virus thymidine kinase suicide gene for recurrent hematologic malignancies after allogeneic hematopoietic stem cell transplantation

artículo científico publicado en 2015

Introduction of Clinical development of Gene-Transferred T-Cell Therapy ⬇️

scholarly article

Investigation of clinical factors associated with longer overall survival in advanced melanoma patients treated with sequential ipilimumab

scientific article published on 04 April 2019

Large-scale comprehensive immunohistochemical biomarker analyses in esophageal squamous cell carcinoma

artículo científico publicado en 2017

Markers for anti-cytotoxic T-lymphocyte antigen 4 (CTLA-4) therapy in melanoma

Metabolic activity by (18)F-FDG-PET/CT is predictive of early response after nivolumab in previously treated NSCLC.

artículo científico publicado en 2017

Microsatellite instability and mismatch repair protein expressions in lymphocyte-predominant breast cancer

artículo científico publicado en 2020

Monocytic CCR2(+) myeloid-derived suppressor cells promote immune escape by limiting activated CD8 T-cell infiltration into the tumor microenvironment

artículo científico publicado en 2011

Nephrotic syndrome with extensive mesangiolysis as a clinical manifestation of chronic graft-versus-host disease (GVHD)

scientific article published on 01 October 2005

Neutrophil-to-lymphocyte ratio and histological type might predict clinical responses to eriburin-based treatment in patients with metastatic breast cancer

artículo científico publicado en 2020

Nivolumab for advanced melanoma: pretreatment prognostic factors and early outcome markers during therapy

scientific article published on 15 October 2016

Paradoxical activation of T cells via augmented ERK signaling mediated by a RAF inhibitor

artículo científico publicado en 2014

Peripheral blood and tumor biomarkers in patients with advanced melanoma treated with combination nivolumab (anti-PD-1, BMS-936558, ONO-4538) and ipilimumab.

artículo científico publicado en 2013

Phase 1 study of abemaciclib, an inhibitor of CDK 4 and 6, as a single agent for Japanese patients with advanced cancer.

artículo científico publicado en 2016

Phase I study of the indoleamine 2,3-dioxygenase 1 inhibitor navoximod (GDC-0919) as monotherapy and in combination with the PD-L1 inhibitor atezolizumab in Japanese patients with advanced solid tumours

artículo científico publicado en 2019

Pretreatment Immune Status Correlates with Progression-Free Survival in Chemotherapy-Treated Metastatic Colorectal Cancer Patients

artículo científico publicado en 2016

Prognostic impact of peripheral blood neutrophil to lymphocyte ratio in advanced-stage pulmonary large cell neuroendocrine carcinoma and its association with the immune-related tumour microenvironment

scientific article published on 30 November 2020

Recent Findings in Tumor Immunology ⬇️

artículo científico publicado en 2019

Reduced argininosuccinate synthetase expression in refractory sarcomas: Impacts on therapeutic potential and drug resistance

artículo científico publicado en 2016

Relationship between the immune microenvironment of different locations in a primary tumour and clinical outcomes of oesophageal squamous cell carcinoma

scientific article published on 25 November 2019

Serial pseudoprogression of metastatic malignant melanoma in a patient treated with nivolumab: a case report

artículo científico publicado en 2017

Severe colitis after PD-1 blockade with nivolumab in advanced melanoma patients: potential role of Th1-dominant immune response in immune-related adverse events: two case reports

scientific article published on 29 October 2019

The peripheral immune status of granulocytic myeloid-derived suppressor cells correlates the survival in advanced gastric cancer patients receiving cisplatin-based chemotherapy

artículo científico publicado en 2017

Tremelimumab-associated tumor regression following after initial progression: two case reports

artículo científico publicado en 2015

Tumor-associated CD204+ M2 macrophages is an unfavorable prognosticator in uterine cervical adenocarcinoma

artículo científico publicado en 2017

Updates in clinical development of immune checkpoint inhibitors

artículo científico publicado en 2017

[Clinical Significance of Ipilimumab and the Combination Therapy as Immune Checkpoint Inhibitor]

scientific article published on 01 June 2019

[III. Recent Clinical Development of Cancer Immunotherapy and Speculation for Bone and Soft Tissue Tumors].

artículo científico publicado en 2017

[Ⅲ.Cross-Organ Developmental Status and Challenges of Immune Checkpoint Inhibitors]

artículo científico publicado en 2019

Lista de obras de

A novel method for evaluating antibody-dependent cell-mediated cytotoxicity by flowcytometry using cryopreserved human peripheral blood mononuclear cells

A phase 1 study of niraparib in Japanese patients with advanced solid tumors ⬇️

Abstract 2813: Clinical impact of immune microenvironment according to intratumoral locations of esophageal squamous cell carcinoma

Abstract LB-019: Anti-CD4 monoclonal antibody immunotherapy exerts an antitumor effect by replacing the T cell receptor repertoire in patients with gastrointestinal cancer

Anti-PD-1 antibody and anti-PD-Li antibody -from basic and clinic-

Antibody responses against NY-ESO-1 and HER2 antigens in patients vaccinated with combinations of cholesteryl pullulan (CHP)-NY-ESO-1 and CHP-HER2 with OK-432

Approach to the Adult Acute Lymphoblastic Leukemia Patient

Association of CD204+ macrophages with poor outcomes of malignant lymphomas not in remission treated by allogeneic HCT

Association of antithyroglobulin antibodies with the development of thyroid dysfunction induced by nivolumab

Biomarkers for Immune Checkpoint Inhibitors in Melanoma

CD20+ tumor-infiltrating immune cells and CD204+ M2 macrophages are associated with prognosis in thymic carcinoma

CD4+ T-cell Immunity in the Peripheral Blood Correlates with Response to Anti-PD-1 Therapy

Chimeric Antigen Receptor T-Cells for the Treatment of B-Cell Acute Lymphoblastic Leukemia.

Clinical Development of Immune Checkpoint Inhibitors

Combination Therapy of Immune Checkpoint Inhibitors

Comparison of tumor-infiltrating lymphocytes between primary and metastatic tumors in breast cancer patients

Complete Pathological Response to Neoadjuvant Pembrolizumab in a Patient With Chemoresistant Upper Urinary Tract Urothelial Carcinoma: A Case Report

Comprehensive immunohistochemical analysis of tumor microenvironment immune status in esophageal squamous cell carcinoma

Computational algorithm-driven evaluation of monocytic myeloid-derived suppressor cell frequency for prediction of clinical outcomes

Correlation between the expression of folate receptor alpha (FRα) and clinicopathological features in patients with lung adenocarcinoma

DNA mismatch repair deficiency in surgically resected lung adenocarcinoma: Microsatellite instability analysis using the Promega panel

Deletion of chromosome arm 15q in a case of minimally differentiated hypoplastic AML-M0

Determination of cellularly processed HLA-A2402-restricted novel CTL epitopes derived from two cancer germ line genes, MAGE-A4 and SAGE

Development of immune checkpoint inhibitor in colorectal cancer

Development of immune checkpoint inhibitors

Diagnostic significance of intratumoral CD8+ tumor-infiltrating lymphocytes in medullary carcinoma

Discovery of a Good Responder Subtype of Esophageal Squamous Cell Carcinoma with Cytotoxic T-Lymphocyte Signatures Activated by Chemoradiotherapy

Do all patients in the phase I oncology trials need to be hospitalized? Domestic but outstanding issues for globalization of drug development in Japan

Donor lymphocytes expressing the herpes simplex virus thymidine kinase suicide gene: detailed immunological function following add-back after haplo-identical transplantation

Dose exploration results from Phase 1 study of cemiplimab, a human monoclonal programmed death (PD)-1 antibody, in Japanese patients with advanced malignancies

Elevated fibrin-related markers in patients with malignant diseases suspected of having thrombotic disorders

Enhancement of antitumor effect by peptide vaccine therapy in combination with anti-CD4 antibody: Study in a murine model

Enhancement of tumor-reactive cytotoxic CD4+ T cell responses after ipilimumab treatment in four advanced melanoma patients

Erratum to: Infusion of donor lymphocytes expressing the herpes simplex virus thymidine kinase suicide gene for recurrent hematologic malignancies after allogeneic hematopoietic stem cell transplantation

Feasibility study of nivolumab as neoadjuvant chemotherapy for locally esophageal carcinoma: FRONTiER (JCOG1804E)

First-in-human phase 1 study of IT1208, a defucosylated humanized anti-CD4 depleting antibody, in patients with advanced solid tumors

First-in-human phase I study of E7090, a novel selective fibroblast growth factor receptor inhibitor, in patients with advanced solid tumors

Generation of peptide-specific CD8+ T cells by phytohemagglutinin-stimulated antigen-mRNA-transduced CD4+ T cells.

Granzyme B is a novel interleukin-18 converting enzyme.

HER2-specific T-cell immune responses in patients vaccinated with truncated HER2 protein complexed with nanogels of cholesteryl pullulan

High Absolute Monocyte Count Predicts Poor Clinical Outcome in Patients with Castration-Resistant Prostate Cancer Treated with Docetaxel Chemotherapy

Histological Characteristics of Lung Adenocarcinoma with Uncommon Actionable Alterations: Special Emphasis on MET exon 14 Skipping Alterations

Humoral immune responses in patients vaccinated with 1-146 HER2 protein complexed with cholesteryl pullulan nanogel

Immune status at pre-treatment impacts on progression-free survival of metastatic colorectal cancer patients treated with first-line chemotherapy.

Immunologic correlates of the abscopal effect in a patient with melanoma

Immunotherapy for genitourinary tumors

Impact of low-dose anti-thymocyte globulin on immune reconstitution after allogeneic hematopoietic cell transplantation

Improved survival among patients enrolled in oncology phase 1 trials in recent decades

Induction of tumoricidal function in CD4+ T cells is associated with concomitant memory and terminally differentiated phenotype

Infection risk with PI3K-AKT-mTOR pathway inhibitors and immune checkpoint inhibitors in patients with advanced solid tumours in phase I clinical trials

Infusion of donor lymphocytes expressing the herpes simplex virus thymidine kinase suicide gene for recurrent hematologic malignancies after allogeneic hematopoietic stem cell transplantation

Introduction of Clinical development of Gene-Transferred T-Cell Therapy ⬇️

Investigation of clinical factors associated with longer overall survival in advanced melanoma patients treated with sequential ipilimumab

Large-scale comprehensive immunohistochemical biomarker analyses in esophageal squamous cell carcinoma

Markers for anti-cytotoxic T-lymphocyte antigen 4 (CTLA-4) therapy in melanoma

Metabolic activity by (18)F-FDG-PET/CT is predictive of early response after nivolumab in previously treated NSCLC.

Microsatellite instability and mismatch repair protein expressions in lymphocyte-predominant breast cancer

Monocytic CCR2(+) myeloid-derived suppressor cells promote immune escape by limiting activated CD8 T-cell infiltration into the tumor microenvironment

Nephrotic syndrome with extensive mesangiolysis as a clinical manifestation of chronic graft-versus-host disease (GVHD)

Neutrophil-to-lymphocyte ratio and histological type might predict clinical responses to eriburin-based treatment in patients with metastatic breast cancer

Nivolumab for advanced melanoma: pretreatment prognostic factors and early outcome markers during therapy

Paradoxical activation of T cells via augmented ERK signaling mediated by a RAF inhibitor

Peripheral blood and tumor biomarkers in patients with advanced melanoma treated with combination nivolumab (anti-PD-1, BMS-936558, ONO-4538) and ipilimumab.

Phase 1 study of abemaciclib, an inhibitor of CDK 4 and 6, as a single agent for Japanese patients with advanced cancer.

Phase I study of the indoleamine 2,3-dioxygenase 1 inhibitor navoximod (GDC-0919) as monotherapy and in combination with the PD-L1 inhibitor atezolizumab in Japanese patients with advanced solid tumours

Pretreatment Immune Status Correlates with Progression-Free Survival in Chemotherapy-Treated Metastatic Colorectal Cancer Patients

Prognostic impact of peripheral blood neutrophil to lymphocyte ratio in advanced-stage pulmonary large cell neuroendocrine carcinoma and its association with the immune-related tumour microenvironment

Recent Findings in Tumor Immunology ⬇️

Reduced argininosuccinate synthetase expression in refractory sarcomas: Impacts on therapeutic potential and drug resistance

Relationship between the immune microenvironment of different locations in a primary tumour and clinical outcomes of oesophageal squamous cell carcinoma

Serial pseudoprogression of metastatic malignant melanoma in a patient treated with nivolumab: a case report

Severe colitis after PD-1 blockade with nivolumab in advanced melanoma patients: potential role of Th1-dominant immune response in immune-related adverse events: two case reports

The peripheral immune status of granulocytic myeloid-derived suppressor cells correlates the survival in advanced gastric cancer patients receiving cisplatin-based chemotherapy

Tremelimumab-associated tumor regression following after initial progression: two case reports

Tumor-associated CD204+ M2 macrophages is an unfavorable prognosticator in uterine cervical adenocarcinoma

Updates in clinical development of immune checkpoint inhibitors

[Clinical Significance of Ipilimumab and the Combination Therapy as Immune Checkpoint Inhibitor]

[III. Recent Clinical Development of Cancer Immunotherapy and Speculation for Bone and Soft Tissue Tumors].

[Ⅲ.Cross-Organ Developmental Status and Challenges of Immune Checkpoint Inhibitors]