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Lista de obras de Dean D. Metcalfe

17-Allylamino-17-demethoxygeldanamycin (17-AAG) is effective in down-regulating mutated, constitutively activated KIT protein in human mast cells

artículo científico publicado en 2003

4. IgE, mast cells, basophils, and eosinophils

artículo científico publicado en 2003

5-hydroxytryptamine induces mast cell adhesion and migration

artículo científico publicado en 2006

5. IgE, mast cells, basophils, and eosinophils

artículo científico publicado en 2006

A Personal Perspective on Mentoring

artículo científico publicado en 2018

A comparison of mediators released or generated by IFN-gamma-treated human mast cells following aggregation of Fc gamma RI or Fc epsilon RI.

artículo científico publicado en 2001

A distinct biomolecular profile identifies monoclonal mast cell disorders in patients with idiopathic anaphylaxis.

artículo científico publicado en 2017

A novel KIT-deficient mouse mast cell model for the examination of human KIT-mediated activation responses

artículo científico publicado en 2013

A novel form of mastocytosis associated with a transmembrane c-kit mutation and response to imatinib

artículo científico publicado en 2003

A pilot study of nonmyeloablative allogeneic hematopoietic stem cell transplant for advanced systemic mastocytosis

scientific article published on 01 February 2006

A proposed classification of mastocytosis incorporating molecular genetics

artículo científico publicado en 2000

A retrospective analysis of bone scan abnormalities in mastocytosis: correlation with disease category and prognosis.

artículo científico publicado en 1994

A study of the use of impulse oscillometry in the evaluation of children with asthma: analysis of lung parameters, order effect, and utility compared with spirometry

artículo científico publicado en 2011

A survey of the number and distribution of mast cells in the skin of patients with mast cell disorders

artículo científico publicado en 1988

A ten-year retrospective analysis of the distribution, use and phenotypic characteristics of the LAD2 human mast cell line.

artículo científico publicado en 2014

A truncated splice-variant of the FcεRIβ receptor subunit is critical for microtubule formation and degranulation in mast cells

artículo científico publicado en 2013

Abnormal bone marrow histopathology in paediatric mastocytosis

artículo científico publicado en 2014

Acoustic rhinometry in the practice of allergy

artículo científico publicado en 2006

Activated lymphocytes induce promoter activity of the TCA3 gene in mast cells following cell-to-cell contact

artículo científico publicado en 1996

Activated mast cells synthesize and release soluble ST2-a decoy receptor for IL-33.

artículo científico publicado en 2015

Activation and function of the mTORC1 pathway in mast cells

artículo científico publicado en 2008

Activation of human mast cells by aggregated IgG through FcgammaRI: additive effects of C3a.

artículo científico publicado en 2004

Activation of human mast cells through the high affinity IgG receptor

artículo científico publicado en 2002

Activation of mast cells by double-stranded RNA: evidence for activation through Toll-like receptor 3.

artículo científico publicado en 2004

Activation of transglutaminase and production of protein-bound gamma-glutamylhistamine in stimulated mouse mast cells

scientific article published on 01 November 1985

Activity of imatinib in systemic mastocytosis with chronic basophilic leukemia and a PRKG2-PDGFRB fusion

artículo científico publicado en 2008

Adrenomedullin is a cross-talk molecule that regulates tumor and mast cell function during human carcinogenesis

artículo científico publicado en 2006

Advanced systemic mastocytosis: from molecular and genetic progress to clinical practice

artículo científico publicado en 2016

Advances in the Classification and Treatment of Mastocytosis: Current Status and Outlook toward the Future.

artículo científico publicado en 2017

Adverse reactions to drugs and biologics in patients with clonal mast cell disorders: A Work Group Report of the Mast Cells Disorder Committee, American Academy of Allergy, Asthma & Immunology

artículo científico publicado en 2018

Aggregation of low affinity IgG receptors induces mast cell adherence to fibronectin: requirement for the common FcR gamma-chain

scientific article published on 01 February 1997

Aggressive systemic mastocytosis and related mast cell disorders: current treatment options and proposed response criteria

artículo científico publicado en 2003

Aldh2 Attenuates Stem Cell Factor/Kit-Dependent Signaling and Activation in Mast Cells ⬇️

artículo científico

Alpha 2-macroglobulin capture allows detection of mast cell chymase in serum and creates a reservoir of angiotensin II-generating activity

artículo científico publicado en 2009

Amplification mechanisms for the enhancement of antigen-mediated mast cell activation

scientific article published on January 2009

An association between susceptibility to experimental autoimmune uveitis and choroidal mast cell numbers ⬇️

artículo científico publicado el 1 de octubre de 1984

An immunohistochemical study of the bone marrow lesions of systemic mastocytosis: expression of stem cell factor by lesional mast cells

scientific article published on 01 August 2002

An optimized protocol for the generation and functional analysis of human mast cells from CD34+ enriched cell populations

artículo científico publicado en 2017

An overview of the controversy concerning questionable manifestations of food allergy

artículo científico publicado en 1987

Analysis of the effect of mast cell granules on lymphocyte blastogenesis in the absence and presence of mitogens: identification of heparin as a granule-associated suppressor factor

artículo científico publicado en 1983

Analysis of the lineage relationship between mast cells and basophils using the c-kit D816V mutation as a biologic signature

artículo científico publicado en 2005

Analysis of the wheal-and-flare reactions that follow the intradermal injection of histamine and morphine in adults with recurrent, unexplained anaphylaxis and systemic mastocytosis

artículo científico publicado en 1989

Anaphylaxis--a practice parameter update 2015

artículo científico publicado en 2015

Anti-IgE treatment of eosinophil-associated gastrointestinal disorders

artículo científico publicado en 2007

Aphidicolin-induced proliferative arrest of murine mast cells: morphological and biochemical changes are not accompanied by alterations in cytokine gene induction ⬇️

artículo científico publicado el 1 de julio de 1992

Arthritis and mast cell activation

artículo científico

Assessing anaphylactic risk? Consider mast cell clonality

artículo científico publicado en 2009

Assessment of clinical findings, tryptase levels, and bone marrow histopathology in the management of pediatric mastocytosis

artículo científico publicado en 2015

Assessment of the extent of cutaneous involvement in children and adults with mastocytosis: relationship to symptomatology, tryptase levels, and bone marrow pathology

artículo científico publicado en 2003

Biochemical and functional characterization of proteoglycans isolated from basophils of patients with chronic myelogenous leukemia ⬇️

artículo científico publicado el 1 de abril de 1984

Biochemical and microscopic evidence for the internalization and degradation of heparin-containing mast cell granules by bovine endothelial cells

artículo científico publicado en 1985

Biomarkers of the involvement of mast cells, basophils and eosinophils in asthma and allergic diseases

artículo científico publicado en 2016

Bone marrow stromal cells use TGF-beta to suppress allergic responses in a mouse model of ragweed-induced asthma

artículo científico publicado en 2010

Btk plays a crucial role in the amplification of Fc epsilonRI-mediated mast cell activation by kit

artículo científico publicado en 2005

Btk-dependent Rac activation and actin rearrangement following FcepsilonRI aggregation promotes enhanced chemotactic responses of mast cells

artículo científico publicado en 2010

C3a and C5a are chemotaxins for human mast cells and act through distinct receptors via a pertussis toxin-sensitive signal transduction pathway

scientific journal article

CD72 negatively regulates KIT-mediated responses in human mast cells

artículo científico publicado en 2010

CRITICAL SIGNALING EVENTS IN THE MECHANOACTIVATION OF HUMAN MAST CELLS VIA P.C492Y-ADGRE2

artículo científico publicado en 2020

Characterization of a mast cell line that lacks the extracellular domain of membrane c-kit

artículo científico publicado en 1997

Characterization of adhesive interactions between mast cells and laminin isoforms: evidence of a principal role for alpha 6 integrin

artículo científico publicado en 1997

Characterization of alpha 5-integrin-dependent mast cell adhesion following Fc epsilon RI aggregation

artículo científico publicado en 2001

Characterization of mast-cell tryptase-expressing peripheral blood cells as basophils

artículo científico publicado en 2002

Characterization of novel stem cell factor responsive human mast cell lines LAD 1 and 2 established from a patient with mast cell sarcoma/leukemia; activation following aggregation of FcepsilonRI or FcgammaRI.

artículo científico publicado en 2003

Chemical constituents of diesel exhaust particles induce IL-4 production and histamine release by human basophils

artículo científico publicado en 2002

Chromogranin A is not a biomarker of mastocytosis

artículo científico publicado en 2017

Classification and diagnosis of mastocytosis: current status

artículo científico publicado en 1991

Clonal analysis of NRAS activating mutations in KIT-D816V systemic mastocytosis

artículo científico publicado en 2010

Cold urticaria, immunodeficiency, and autoimmunity related to PLCG2 deletions

artículo científico publicado en 2012

Comparison of FcϵRI‐ and FcγRI‐mediated degranulation and TNF‐α synthesis in human mast cells: selective utilization of phosphatidylinositol‐3‐kinase for FcγRI‐induced degranulation ⬇️

artículo científico publicado el 1 de mayo de 2003

Concurrent inhibition of kit- and FcepsilonRI-mediated signaling: coordinated suppression of mast cell activation

artículo científico publicado en 2007

Consensus Opinion on Allogeneic Hematopoietic Cell Transplantation in Advanced Systemic Mastocytosis.

artículo científico publicado en 2016

Contemporary issues in food allergy: seafood toxin-induced disease in the differential diagnosis of allergic reactions.

artículo científico publicado en 2005

Controversies in Allergy: Is a Bone Marrow Biopsy Optional or Essential in the Evaluation of the Patient with a Suspected Mast Cell Disorder?

scientific article published on 08 January 2019

Cutaneous manifestations in patients with mastocytosis: Consensus report of the European Competence Network on Mastocytosis; the American Academy of Allergy, Asthma & Immunology; and the European Academy of Allergology and Clinical Immunology

artículo científico

Definitions, criteria and global classification of mast cell disorders with special reference to mast cell activation syndromes: a consensus proposal

artículo científico publicado en 2011

Degradation of the heparin matrix of mast cell granules by cultured fibroblasts

artículo científico publicado en 1983

Demonstration and characterization of a transient arthritis in rats following sensitization of synovial mast cells with antigen-specific IgE and parenteral challenge with specific antigen

artículo científico publicado en 1988

Demonstration of an aberrant mast-cell population with clonal markers in a subset of patients with "idiopathic" anaphylaxis

artículo científico publicado en 2007

Demonstration of differential effects of cytokines on mast cells derived from murine bone marrow and peripheral blood mononuclear cells

artículo científico publicado el 1 de noviembre de 1994

Demonstration of the origin of human mast cells from CD34+ bone marrow progenitor cells ⬇️

artículo científico publicado el 1 de marzo de 1991

Demonstration that human mast cells arise from a progenitor cell population that is CD34(+), c-kit(+), and expresses aminopeptidase N (CD13)

scientific article published on 01 October 1999

Demonstration that mast cells, T cells, and B cells bearing the activating kit mutation D816V occur in clusters within the marrow of patients with mastocytosis

artículo científico publicado en 2004

Description and Characterization of a Novel Human Mast Cell Line for Scientific Study

scientific article published on 06 November 2019

Detection of KIT D816V in peripheral blood of children with manifestations of cutaneous mastocytosis suggests systemic disease

artículo científico publicado en 2018

Determination of protein phosphorylation in Fc epsilon RI-activated human mast cells by immunoblot analysis requires protein extraction under denaturing conditions

artículo científico publicado en 2002

Diagnosis and treatment of cutaneous mastocytosis in children: practical recommendations

scientific article published on August 2011

Diagnosis and treatment of systemic mastocytosis: state of the art.

artículo científico publicado en 2003

Diagnosis, Classification and Management of Mast Cell Activation Syndromes (MCAS) in the Era of Personalized Medicine

artículo científico publicado en 2020

Diagnostic criteria and classification of mastocytosis: a consensus proposal

artículo científico publicado en 2001

Diminution of signal transducer and activator of transcription 3 signaling inhibits vascular permeability and anaphylaxis

artículo científico publicado en 2016

Dissociation between history and challenge in patients with physical urticaria

artículo científico publicado en 2014

Distinct PGE2-responder and non-responder phenotypes in human mast cell populations: "all or nothing" enhancement of antigen-dependent mediator release

artículo científico publicado en 2011

Distinct transcriptome profiles differentiate nonsteroidal anti-inflammatory drug-dependent from nonsteroidal anti-inflammatory drug-independent food-induced anaphylaxis.

artículo científico publicado en 2015

Early expression of high-affinity receptor for immunoglobulin E (Fc epsilon RI) during differentiation of mouse mast cells and human basophils

artículo científico publicado en 1990

Effect of IL-3 and stem cell factor on the appearance of human basophils and mast cells from CD34+ pluripotent progenitor cells ⬇️

artículo científico publicado el 1 de febrero de 1992

Effect of lipopolysaccharide (LPS) and peptidoglycan (PGN) on human mast cell numbers, cytokine production, and protease composition

artículo científico publicado en 2008

Effects of gamma radiation on FcepsilonRI and TLR-mediated mast cell activation.

artículo científico publicado en 2007

Effects of tixocortol pivalate on gastrointestinal disease in systemic mastocytosis: a preliminary study

artículo científico publicado en 1991

Effects of tyrosine kinase inhibitor STI571 on human mast cells bearing wild-type or mutated c-kit

artículo científico publicado en 2003

Elevated basal serum tryptase identifies a multisystem disorder associated with increased TPSAB1 copy number

artículo científico

Elevated serum tryptase levels identify a subset of patients with a myeloproliferative variant of idiopathic hypereosinophilic syndrome associated with tissue fibrosis, poor prognosis, and imatinib responsiveness

artículo científico publicado en 2003

Elevated tryptase levels are associated with greater bone density in a cohort of patients with mastocytosis

artículo científico publicado en 2006

Elevation in histamine and tryptase following exercise in patients with mastocytosis

scientific article published on 23 July 2018

Endosomal trafficking of the ligated FcvarepsilonRI receptor.

artículo científico publicado en 2008

Endothelins belong to the assortment of mast cell-derived and mast cell-bound cytokines

artículo científico publicado el 1 de febrero de 1992

Eotaxin potentiates antigen-dependent basophil IL-4 production

artículo científico publicado en 1999

Estrogen increases the severity of anaphylaxis in female mice through enhanced endothelial nitric oxide synthase expression and nitric oxide production

artículo científico publicado en 2014

Evidence for the involvement of a hematopoietic progenitor cell in systemic mastocytosis from single-cell analysis of mutations in the c-kit gene

scientific article published on 01 July 2002

Examination of the role of TRPM8 in human mast cell activation and its relevance to the etiology of cold-induced urticaria

artículo científico publicado en 2011

Exon skipping of FcεRIβ eliminates expression of the high-affinity IgE receptor in mast cells with therapeutic potential for allergy

artículo científico publicado en 2016

F(ab)'2-mediated neutralization of C3a and C5a anaphylatoxins: a novel effector function of immunoglobulins

artículo científico publicado en 2003

Factors affecting the determination of threshold doses for allergenic foods: how much is too much?

article

Fas (CD95, APO-1) antigen expression and function in murine mast cells ⬇️

artículo científico publicado el 15 de octubre de 1997

FcepsilonRI- and Fcgamma receptor-mediated production of reactive oxygen species by mast cells is lipoxygenase- and cyclooxygenase-dependent and NADPH oxidase-independent

artículo científico publicado en 2007

Fcgamma receptors on mast cells: activatory and inhibitory regulation of mediator release

artículo científico publicado en 2004

Fibroblasts determine the fate of Fc epsilon RI+ cell populations in vitro by selectively supporting the viability of mast cells while internalizing and degrading basophils

artículo científico publicado en 1994

Flow cytometric analysis for cytokine production identifies T helper 1, T helper 2, and T helper 0 cells within the human CD4+CD27- lymphocyte subpopulation

scientific article published on 01 May 1995

Functional and biochemical characterization of rat bone marrow derived mast cells.

artículo científico publicado en 1988

Functional and phenotypic studies of two variants of a human mast cell line with a distinct set of mutations in the c-kit proto-oncogene

artículo científico publicado en 2003

Functional deregulation of KIT: link to mast cell proliferative diseases and other neoplasms

artículo científico publicado en 2014

GATA-2-deficient mast cells limit IgE-mediated immediate hypersensitivity reactions in human subjects

artículo científico publicado en 2019

Gene expression analysis in mastocytosis reveals a highly consistent profile with candidate molecular markers

artículo científico publicado en 2003

Generalized erythematous macules and plaques associated with flushing, repeated syncope, and refractory anemia

artículo científico publicado en 2002

Genetically modified crops and allergenicity

artículo científico publicado en 2005

Glucocorticoids decrease tissue mast cell number by reducing the production of the c-kit ligand, stem cell factor, by resident cells: in vitro and in vivo evidence in murine systems

scientific article published on April 1997

Glycogen synthase kinase 3beta activation is a prerequisite signal for cytokine production and chemotaxis in human mast cells

artículo científico publicado en 2009

Glycogen synthase kinase-3β is a prosurvival signal for the maintenance of human mast cell homeostasis

artículo científico publicado en 2011

Glycomic analysis of human mast cells, eosinophils and basophils

artículo científico publicado en 2011

Glycosaminoglycan profiles in cloned granulated lymphocytes with natural killer function and in cultured mast cells: their potential use as biochemical markers

artículo científico publicado en 1984

Growth of human mast cells from bone marrow and peripheral blood-derived CD34(+) pluripotent hematopoietic cells.

artículo científico publicado en 2015

Growth of human mast cells from bone marrow and peripheral blood-derived CD34+ pluripotent progenitor cells

artículo científico publicado en 2006

Hematologic manifestations of systemic mast cell disease: A prospective study of laboratory and morphologic features and their relation to prognosis ⬇️

artículo científico publicado el 1 de diciembre de 1991

Hepatic involvement in mastocytosis: clinicopathologic correlations in 41 cases

artículo científico publicado en 1995

Heritable risk for severe anaphylaxis associated with increased α-tryptase-encoding germline copy number at TPSAB1

artículo científico publicado en 2020

Heterogeneity of mast cells in the tissues of the respiratory tract and other organ systems

artículo científico publicado en 1987

High-resolution tracking of cell division demonstrates differential effects of TH1 and TH2 cytokines on SCF-dependent human mast cell production in vitro: correlation with apoptosis and Kit expression

artículo científico publicado en 2004

Human dendritic cell 1 and dendritic cell 2 subsets express FcepsilonRI: correlation with serum IgE and allergic asthma

artículo científico publicado en 2003

Human macrophages cultured on agar but not agarose resemble mast cells

artículo científico publicado en 1989

Human mast cells are capable of serotonin synthesis and release

scientific article published on 13 October 2006

Human mast cells express functional TrkA and are a source of nerve growth factor.

artículo científico publicado en 1997

Human mast cells express the hyaluronic-acid-binding isoform of CD44 and adhere to hyaluronic acid

scientific article published on 01 March 2000

Human mast cells produce the CD4+ T lymphocyte chemoattractant factor, IL-16 ⬇️

artículo científico publicado el 15 de septiembre de 1997

Human mast cells synthesize and release angiogenin, a member of the ribonuclease A (RNase A) superfamily

scientific article published on 22 July 2009

Human tissue mast cells are an inducible reservoir of persistent HIV infection

artículo científico publicado en 2007

IL-3-dependent growth of basophil-like cells and mastlike cells from human bone marrow

scientific article published on 01 April 1989

IL-3-dependent mast cells attach to plate-bound vitronectin. Demonstration of augmented proliferation in response to signals transduced via cell surface vitronectin receptors

artículo científico publicado en 1992

IL-3-dependent murine mast cells undergo apoptosis on removal of IL-3. Prevention of apoptosis by c-kit ligand ⬇️

artículo científico publicado el 1 de octubre de 1993

IL-33 induces a hyporesponsive phenotype in human and mouse mast cells.

artículo científico publicado en 2012

IL-5 receptor α levels in patients with marked eosinophilia or mastocytosis

artículo científico publicado en 2011

IL-6 levels predict disease variant and extent of organ involvement in patients with mastocytosis

artículo científico publicado en 2005

IL-6 promotes an increase in human mast cell numbers and reactivity through suppression of suppressor of cytokine signaling 3.

artículo científico publicado en 2016

Identification and categorization of inducible mast cell genes in a subtraction library

artículo científico publicado en 1998

Identification and characterization of the inducible murine mast cell gene, imc-415.

artículo científico publicado en 1998

Identification of Fyn-binding proteins in MC/9 mast cells using mass spectrometry ⬇️

artículo científico publicado el 10 de octubre de 2003

Identification of a point mutation in the catalytic domain of the protooncogene c-kit in peripheral blood mononuclear cells of patients who have mastocytosis with an associated hematologic disorder

artículo científico publicado en 1995

Identification of a polymorphism in the transmembrane domain of the protooncogene c-kit in healthy subjects

scientific article published on 01 January 1996

Identification of an amino acid sequence in the laminin A chain mediating mast cell attachment and spreading.

artículo científico publicado en 1991

Identification of chondroitin sulfate E in human lung mast cells ⬇️

artículo científico publicado el 15 de abril de 1988

IgE(+), Kit(-), I-A/I-E(-) myeloid cells are the initial source of Il-4 after antigen challenge in a mouse model of allergic pulmonary inflammation.

artículo científico publicado en 2002

IgE, mast cells, basophils, and eosinophils

artículo científico publicado en 2010

IgE-FcepsilonRI interactions determine HIV coreceptor usage and susceptibility to infection during ontogeny of mast cells

artículo científico publicado en 2009

Immortalization of Mouse Bone Marrow-Derived Mast Cells with Ad12-SV40 Virus ⬇️

artículo científico publicado el 1 de enero de 1993

Immune surveillance by mast cells during dengue infection promotes natural killer (NK) and NKT-cell recruitment and viral clearance

artículo científico publicado en 2011

Immunophenotypic and Ultrastructural Analysis of Mast Cells in Hermansky-Pudlak Syndrome Type-1: A Possible Connection to Pulmonary Fibrosis

artículo científico publicado en 2016

Impact of naturally forming human α/β-tryptase heterotetramers in the pathogenesis of hereditary α-tryptasemia

artículo científico publicado en 2019

Impaired function of bone marrow stromal cells in systemic mastocytosis

artículo científico publicado en 2015

Impulse oscillometry identifies peripheral airway dysfunction in children with adenosine deaminase deficiency

artículo científico publicado en 2015

Impulse oscillometry in the evaluation of diseases of the airways in children ⬇️

artículo científico publicado el 6 de enero de 2011

Induction and enhancement of Fc(epsilon)RI-dependent mast cell degranulation following coculture with activated T cells: dependency on ICAM-1- and leukocyte function-associated antigen (LFA)-1-mediated heterotypic aggregation

scientific article published on 01 April 1998

Inhibition of Allergic Reactivity through Targeting FcεRI-Bound IgE with Humanized Low-Affinity Antibodies

scientific article published on 21 October 2019

Inhibition of IgE-mediated mast cell degranulation by sulphasalazine

artículo científico publicado en 1985

Inhibition of the growth of IL-3-dependent mast cells from murine bone marrow by recombinant granulocyte macrophage-colony-stimulating factor.

artículo científico publicado en 1989

Interaction of DJ-1 with Lyn is essential for IgE-mediated stimulation of human mast cells

artículo científico publicado en 2017

Interaction of mast cells with extracellular matrix proteins

artículo científico publicado en 1995

Interactions between mast cells, fibroblasts and connective tissue components

artículo científico publicado en 1985

Interferon-γ enhances both the anti-bacterial and the pro-inflammatory response of human mast cells to Staphylococcus aureus.

artículo científico publicado en 2015

International Working Group-Myeloproliferative Neoplasms Research and Treatment (IWG-MRT) & European Competence Network on Mastocytosis (ECNM) consensus response criteria in advanced systemic mastocytosis.

artículo científico publicado en 2013

Introduction: what are the issues in addressing the allergenic potential of genetically modified foods?

artículo científico publicado en 2003

Isolation and Characterization of Heparin from Human Lung ⬇️

artículo científico publicado el 1 de diciembre de 1979

Isolation and characterization of sulphated mucopolysaccharides from rat leukaemic (RBL-1) basophils

artículo científico publicado en 1980

Isolation of Tissue Mast Cells ⬇️

artículo científico publicado el 1 de agosto de 2010

KIT D816V-associated systemic mastocytosis with eosinophilia and FIP1L1/PDGFRA-associated chronic eosinophilic leukemia are distinct entities

artículo científico publicado en 2007

KIT GNNK splice variants: expression in systemic mastocytosis and influence on the activating potential of the D816V mutation in mast cells

artículo científico publicado en 2013

KIT signaling regulates MITF expression through miRNAs in normal and malignant mast cell proliferation ⬇️

artículo científico publicado el 27 de enero de 2011

Kinetics of the appearance of Fc epsilon RI-bearing cells in interleukin-3-dependent mouse bone marrow cultures: correlation with histamine content and mast cell maturation

artículo científico publicado en 1992

Kit and FcepsilonRI mediate unique and convergent signals for release of inflammatory mediators from human mast cells

artículo científico publicado en 2004

Kit- and Fc epsilonRI-induced differential phosphorylation of the transmembrane adaptor molecule NTAL/LAB/LAT2 allows flexibility in its scaffolding function in mast cells

scientific journal article

Knockout of the Trpc1 gene reveals that TRPC1 can promote recovery from anaphylaxis by negatively regulating mast cell TNF-α production

artículo científico publicado en 2013

Laminin promotes mast cell attachment

Levels of mast-cell growth factors in plasma and in suction skin blister fluid in adults with mastocytosis: correlation with dermal mast-cell numbers and mast-cell tryptase

artículo científico publicado en 2002

Loss of SOCS7 in mice results in severe cutaneous disease and increased mast cell activation.

artículo científico publicado en 2009

Maculopapular Cutaneous Mastocytosis in a Diverse Population

scientific article published on 02 May 2019

Mast Cells Signal their Importance in Health and Disease

artículo científico publicado en 2018

Mast cell activation syndrome: Importance of consensus criteria and call for research

scientific article published on 19 June 2018

Mast cell activation syndrome: Proposed diagnostic criteria.

artículo científico publicado en 2010

Mast cell adhesion to fibronectin.

artículo científico publicado en 1991

Mast cell biology in evolution

scientific article published on 11 May 2006

Mast cell biology: introduction and overview

artículo científico publicado en 2011

Mast cell dependent vascular changes associated with an acute response to cold immersion in primary contact urticaria

artículo científico publicado en 2013

Mast cell heterogeneity in higher animals: a comparison of the properties of autologous lung and intestinal mast cells from nonhuman primates.

artículo científico publicado en 1986

Mast cell mediators with emphasis on intestinal mast cells

artículo científico publicado en 1984

Mast cell migratory response to interleukin-8 is mediated through interaction with chemokine receptor CXCR2/Interleukin-8RB.

artículo científico publicado en 1999

Mast cell ontogeny and apoptosis

artículo científico publicado en 1995

Mast cell proliferative disorders: current view on variants recognized by the World Health Organization

artículo científico publicado en 2003

Mast cell-T cell interactions

artículo científico publicado en 1999

Mast cells and arthritis

artículo científico publicado en 1988

Mast cells and mastocytosis

artículo científico publicado en 2008

Mast cells chemotax to laminin with enhancement after IgE-mediated activation

artículo científico publicado en 1989

Mast cells cultured from the peripheral blood of normal donors and patients with mastocytosis originate from a CD34+/Fc epsilon RI- cell population ⬇️

artículo científico publicado el 15 de octubre de 1994

Mast cells in allergy and host defense

artículo científico publicado en 2001

Mast cells in cutaneous mastocytosis: accumulation of the MCTC type

artículo científico publicado en 1990

Mast cells in innate immunity

artículo científico publicado en 2000

Mast cells, basophils and mastocytosis

Mast cells, which interact with Escherichia coli, up-regulate genes associated with innate immunity and become less responsive to Fc(epsilon)RI-mediated activation.

artículo científico publicado en 2005

Mastocytosis

artículo científico publicado en 2013

Mastocytosis

artículo científico publicado en 1989

Mastocytosis

scientific article published on 01 January 2005

Mastocytosis

artículo científico publicado en 2010

Mastocytosis and disorders of mast cell proliferation

artículo científico publicado en 2002

Mastocytosis associated with a rare germline KIT K509I mutation displays a well-differentiated mast cell phenotype

artículo científico publicado en 2014

Mastocytosis complicating pregnancy

artículo científico publicado en 2000

Mastocytosis in infants and children: recognition of patterns of skin disease

artículo científico publicado en 1989

Mastocytosis-derived extracellular vesicles exhibit a mast cell signature, transfer KIT to stellate cells, and promote their activation

artículo científico publicado en 2018

Mastocytosis: 2016 updated WHO classification and novel emerging treatment concepts

artículo científico publicado en 2016

Mastocytosis: current concepts in diagnosis and treatment

artículo científico publicado en 2002

Mastocytosis: current treatment concepts

artículo científico publicado en 2002

Mastocytosis: pathology, genetics, and current options for therapy

artículo científico publicado en 2005

Mechanisms of mast cell signaling in anaphylaxis

artículo científico publicado en 2009

Molecular remission and reversal of myelofibrosis in response to imatinib mesylate treatment in patients with the myeloproliferative variant of hypereosinophilic syndrome

artículo científico publicado en 2004

Mouse heparin proteoglycan. Synthesis by mast cell-fibroblast monolayers during lymphocyte-dependent mast cell proliferation.

artículo científico publicado en 1982

Multiple bidirectional alterations of phenotype and changes in proliferative potential during the in vitro and in vivo passage of clonal mast cell populations derived from mouse peritoneal mast cells ⬇️

artículo científico publicado el 1 de septiembre de 1988

Murine mast cells synthesize basement membrane components. A potential role in early fibrosis

artículo científico publicado en 1991

NTAL phosphorylation is a pivotal link between the signaling cascades leading to human mast cell degranulation following Kit activation and Fc epsilon RI aggregation

artículo científico publicado en 2004

Nitric oxide inhibits IgE-dependent cytokine production and Fos and Jun activation in mast cells

artículo científico publicado en 2004

Office-based management of urticaria

artículo científico publicado en 2008

Omalizumab for the treatment of unprovoked anaphylaxis in patients with systemic mastocytosis

scientific article published on 03 May 2007

On the way to targeted therapy of mast cell neoplasms: identification of molecular targets in neoplastic mast cells and evaluation of arising treatment concepts.

artículo científico publicado en 2004

Oncogenic D816V-KIT signaling in mast cells causes persistent IL-6 production

artículo científico publicado en 2019

Paediatric mastocytosis

artículo científico publicado en 2002

Passive cutaneous anaphylaxis in mouse skin is associated with local accumulation of interleukin-6 mRNA and immunoreactive interleukin-6 protein

artículo científico publicado el 1 de noviembre de 1992

Pathogenesis and Pathology of Mastocytosis

artículo científico publicado en 2017

Patterns of skeletal scintigraphy and their relationship to plasma and urinary histamine levels in systemic mastocytosis ⬇️

artículo científico publicado el 1 de agosto de 1984

Pediatric mastocytosis

artículo científico publicado en 2000

Pediatric mastocytosis

scientific article published on 01 March 1991

Pediatric mastocytosis

scientific article published on 01 September 1994

Pediatric mastocytosis: routine anesthetic management for a complex disease

artículo científico publicado en 2008

Pediatric-onset mastocytosis: a long term clinical follow-up and correlation with bone marrow histopathology

artículo científico publicado en 2009

Phagocytosis of mast cell granules by cultured fibroblasts

artículo científico publicado en 1983

Polydispersity of rat mast cell heparin. Implications for proteoglycan assembly

artículo científico publicado en 1980

Preclinical human models and emerging therapeutics for advanced systemic mastocytosis

scientific article published on 05 July 2018

Prevention of F-actin assembly switches the response to SCF from chemotaxis to degranulation in human mast cells

artículo científico publicado en 2013

Production of granulocyte-macrophage colony-stimulating factor by primary cultures of unstimulated rat microvascular endothelial cells

artículo científico publicado en 1988

Proposed Diagnostic Algorithm for Patients with Suspected Mast Cell Activation Syndrome

scientific article published on 05 February 2019

Proposed Terminology and Classification of Pre-Malignant Neoplastic Conditions: A Consensus Proposal

artículo científico publicado en 2017

Prostaglandin E2 activates and utilizes mTORC2 as a central signaling locus for the regulation of mast cell chemotaxis and mediator release ⬇️

artículo científico publicado el 27 de octubre de 2010

Providing the TORC for cell cycle progression in neoplastic mast cells

artículo científico publicado en 2012

Pulmonary and ovarian manifestations of systemic mastocytosis

scientific article published on 01 April 1996

Radiotherapy of refractory bone pain due to systemic mast cell disease

artículo científico publicado en 1994

Receptor-mediated modulation of murine mast cell function by alpha-melanocyte stimulating hormone.

artículo científico publicado en 1999

Refinements in response criteria in systemic mastocytosis: reply to a proposal

scientific article published on 26 April 2010

Regression of urticaria pigmentosa in adult patients with systemic mastocytosis: correlation with clinical patterns of disease

artículo científico publicado en 2002

Regulation of Reactive Oxygen Species and the Antioxidant Protein DJ-1 in Mastocytosis

artículo científico publicado en 2016

Regulation of adhesion of mouse bone marrow-derived mast cells to laminin

artículo científico publicado en 1990

Regulation of normal and neoplastic human mast cell development in mastocytosis.

artículo científico publicado en 2005

Reply

Reply: To PMID 25553642.

artículo científico publicado en 2015

Rictor negatively regulates high-affinity receptors for IgE-induced mast cell degranulation

artículo científico publicado en 2014

Risk and Management of Patients with Mastocytosis and MCAS in the SARS-CoV-2 (COVID-19) Pandemic: Expert Opinions

scientific article published on 16 June 2020

Risk assessment in anaphylaxis: current and future approaches

artículo científico publicado en 2007

Rodent and human mast cells produce functionally significant intracellular reactive oxygen species but not nitric oxide

artículo científico publicado en 2004

Roles of adaptor molecules in mast cell activation

artículo científico publicado en 2005

S1P₄ Regulates Passive Systemic Anaphylaxis in Mice but Is Dispensable for Canonical IgE-Mediated Responses in Mast Cells.

artículo científico publicado en 2018

Second symposium on the definition and management of anaphylaxis: summary report--Second National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network symposium.

artículo científico publicado en 2006

Second symposium on the definition and management of anaphylaxis: summary report--second National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network symposium.

artículo científico publicado en 2006

Secretion of interleukin-1 receptor antagonist from human mast cells after immunoglobulin E-mediated activation and after segmental antigen challenge

artículo científico publicado en 2001

Sequential Appearance of Basophils and Mast Cells from Human Bone Marrow in Long-Term Suspension Culture ⬇️

artículo científico publicado el 1 de enero de 1990

Serum tryptase levels in atopic and nonatopic children

artículo científico publicado en 2009

Sialic acid-binding immunoglobulin-like lectin (Siglec) 8 in patients with eosinophilic disorders: Receptor expression and targeting using chimeric antibodies

artículo científico publicado en 2018

Silica-directed mast cell activation is enhanced by scavenger receptors

artículo científico publicado en 2006

Skewed Lymphocyte Subpopulations and Associated Phenotypes in Patients with Mastocytosis

scientific article published on 15 July 2019

Slowly progressive systemic mastocytosis with high mast-cell burden and no evidence of a non-mast-cell hematologic disorder: an example of a smoldering case?

artículo científico publicado en 2001

Smouldering mastocytosis: a novel subtype of systemic mastocytosis with slow progression

artículo científico publicado en 2002

Solar Urticaria.

artículo científico publicado en 2015

Soluble stem cell factor receptor (CD117) and IL-2 receptor alpha chain (CD25) levels in the plasma of patients with mastocytosis: relationships to disease severity and bone marrow pathology

scientific article published on 01 August 2000

Standards and standardization in mastocytosis: consensus statements on diagnostics, treatment recommendations and response criteria

artículo científico publicado en 2007

Stem cell factor induces mast cell adhesion to fibronectin.

artículo científico publicado en 1994

Stem cell factor programs the mast cell activation phenotype

artículo científico publicado en 2012

Subvisible Particle Content, Formulation, and Dose of an Erythropoietin Peptide Mimetic Product Are Associated With Severe Adverse Postmarketing Events

artículo científico publicado en 2016

Surrogate markers of disease in mastocytosis.

artículo científico publicado en 2002

Symposium on the definition and management of anaphylaxis: summary report.

artículo científico publicado en 2005

Synergistic activation of phospholipases Cgamma and Cbeta: a novel mechanism for PI3K-independent enhancement of FcepsilonRI-induced mast cell mediator release

artículo científico publicado en 2008

Systemic mastocytosis

scientific article published on 01 January 2004

Systemic mastocytosis

artículo científico publicado en 2006

Systemic mastocytosis: CT and US features of abdominal manifestations

scientific article published on 01 February 1997

TLR-mediated signaling pathways circumvent the requirement for DAP12 in mast cells for the induction of inflammatory mediator release

artículo científico publicado en 2010

Targeting Sphingosine Kinase Isoforms Effectively Reduces Growth and Survival of Neoplastic Mast Cells With D816V-KIT.

artículo científico publicado en 2018

Targeting kit activation: a potential therapeutic approach in the treatment of allergic inflammation

artículo científico publicado en 2007

Telangiectasia macularis eruptiva perstans or highly vascularized urticaria pigmentosa?

artículo científico publicado en 2014

The CD20 homologue MS4A4 directs trafficking of KIT toward clathrin-independent endocytosis pathways and thus regulates receptor signaling and recycling

artículo científico publicado en 2015

The FcεRIβ homologue, MS4A4A, promotes FcεRI signal transduction and store-operated Ca2+ entry in human mast cells

artículo científico publicado en 2020

The Kit-activating mutation D816V enhances stem cell factor--dependent chemotaxis

artículo científico publicado en 2001

The biology of Kit in disease and the application of pharmacogenetics

artículo científico publicado en 2004

The c-KIT mutation causing human mastocytosis is resistant to STI571 and other KIT kinase inhibitors; kinases with enzymatic site mutations show different inhibitor sensitivity profiles than wild-type kinases and those with regulatory-type mutations

artículo científico publicado en 2002

The classification of systemic mastocytosis should include mast cell leukemia (MCL) and systemic mastocytosis with a clonal hematologic non-mast cell lineage disease (SM-AHNMD)

artículo científico publicado en 2010

The effects of aspartame on mast cells and basophils

artículo científico publicado en 1986

The effects of stem cell factor on the ultrastructure of Fc epsilon RI+ cells developing in IL-3-dependent murine bone marrow-derived cell cultures ⬇️

artículo científico publicado el 1 de noviembre de 1993

The high-affinity immunoglobulin-E receptor (FcepsilonRI) is endocytosed by an AP-2/clathrin-independent, dynamin-dependent mechanism

artículo científico publicado en 2006

The histologic and functional characterization of enzymatically dispersed intestinal mast cells of nonhuman primates: effects of secretagogues and anti-allergic drugs on histamine secretion.

artículo científico publicado en 1985

The liver, spleen, and lymph nodes in mastocytosis

artículo científico publicado en 1991

The mast cell

artículo científico publicado en 1981

The phosphoinositide 3-kinase-dependent activation of Btk is required for optimal eicosanoid production and generation of reactive oxygen species in antigen-stimulated mast cells

artículo científico publicado en 2008

The phospholipase C gamma 1-dependent pathway of Fc epsilon RI-mediated mast cell activation is regulated independently of phosphatidylinositol 3-kinase

artículo científico publicado en 2003

The protooncogene c-kit and c-kit ligand in human disease☆☆☆★ ⬇️

artículo científico publicado el 1 de octubre de 1997

The role of c-Kit and its ligand, stem cell factor, in mast cell apoptosis

artículo científico publicado en 1995

The role of reactive oxygen species and nitric oxide in mast cell-dependent inflammatory processes

artículo científico publicado en 2007

The treatment of mastocytosis: an overview

artículo científico publicado en 1991

Thrombopoietin alone or in the presence of stem cell factor supports the growth of KIT(CD117)low/ MPL(CD110)+ human mast cells from hematopoietic progenitor cells

artículo científico publicado en 2005

Transcriptional regulation of the TCA3 gene in mast cells after Fc epsilon RI cross-linking

artículo científico publicado en 1994

Transforming growth factor-beta prevents stem cell factor-mediated rescue of mast cells from apoptosis after IL-3 deprivation

artículo científico publicado en 1994

Treatment of systemic mastocytosis

artículo científico publicado en 2006

Tryptase haplotype in mastocytosis: relationship to disease variant and diagnostic utility of total tryptase levels

artículo científico publicado en 2007

Tryptase levels as an indicator of mast-cell activation in systemic anaphylaxis and mastocytosis.

artículo científico publicado en 1987

Twelve-year follow-up of omalizumab therapy for anaphylaxis in 2 patients with systemic mastocytosis

artículo científico publicado en 2018

Two different negative regulatory elements control the transcription of T-cell activation gene 3 in activated mast cells

artículo científico publicado en 1997

Ultrastructural localization of heparin to human mast cells of the MCTC and MCT types by labeling with antithrombin III-gold.

artículo científico publicado en 1993

Ultrastructural, biochemical, and functional characteristics of histamine-containing cells cloned from mouse bone marrow: tentative identification as mucosal mast cells

artículo científico publicado en 1983

Understanding the mechanisms of anaphylaxis

scientific article published on August 2008

Vibratory Urticaria Associated with a Missense Variant in ADGRE2.

artículo científico publicado en 2016

Vibratory Urticaria and ADGRE2

artículo científico publicado en 2016

Vocal cord dysfunction as demonstrated by impulse oscillometry

artículo científico publicado en 2013

WAO International Scientific Conference (WISC 2016) Abstracts: Jerusalem, Israel. 6–9 December 2016.

artículo científico publicado en 2017

What is food to one ...

artículo científico publicado en 1984

Why the 20% + 2 Tryptase Formula Is a Diagnostic Gold Standard for Severe Systemic Mast Cell Activation and Mast Cell Activation Syndrome

artículo científico publicado en 2019

mTORC1 and mTORC2 differentially regulate homeostasis of neoplastic and non-neoplastic human mast cells

artículo científico publicado en 2011

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