Lista de obras -

APR-246 reactivates mutant p53 by targeting cysteines 124 and 277.

artículo científico publicado en 2018

Aberration of the enzymatic activity of Fhit tumor suppressor protein enhances cancer cell death upon photodynamic therapy similarly to that driven by wild-type Fhit.

artículo científico publicado en 2009

Activation of TAp73 and inhibition of TrxR by Verteporfin for improved cancer therapy in mutant pancreatic tumors

Correction to: Reactivation of TAp73 tumor suppressor by protoporphyrin IX, a metabolite of aminolevulinic acid, induces apoptosis in TP53-deficient cancer cells

scientific article published on 29 August 2019

Correction: APR-246 reactivates mutant p53 by targeting cysteines 124 and 277

artículo científico publicado en 2019

Enlightened protein: Fhit tumor suppressor protein structure and function and its role in the toxicity of protoporphyrin IX-mediated photodynamic reaction.

artículo científico publicado en 2009

Evaluation of the role of the pharmacological inhibition of Staphylococcus aureus multidrug resistance pumps and the variable levels of the uptake of the sensitizer in the strain-dependent response of Staphylococcus aureus to PPArg(2)-based photodyn

artículo científico publicado en 2010

Expression and simple, one-step purification of fragile histidine triad (Fhit) tumor suppressor mutant forms in Escherichia coli and their interaction with protoporphyrin IX.

artículo científico publicado en 2007

Induction of apoptosis in HL-60 cells through the ROS-mediated mitochondrial pathway by ramentaceone from Drosera aliciae.

artículo científico publicado en 2012

Inhibition of glycolytic enzymes mediated by pharmacologically activated p53: targeting Warburg effect to fight cancer

artículo científico publicado en 2011

Pharmacological activation of tumor suppressor, wild-type p53 as a promising strategy to fight cancer

artículo científico publicado el 20 de agosto de 2010

Plumbagin induces apoptosis in Her2-overexpressing breast cancer cells through the mitochondrial-mediated pathway.

artículo científico publicado en 2012

Protoporphyrin IX induces apoptosis in HeLa cells prior to photodynamic treatment

artículo científico publicado en 2007

Protoporphyrin IX interacts with wild-type p53 protein in vitro and induces cell death of human colon cancer cells in a p53-dependent and -independent manner

artículo científico publicado en 2006

Protoporphyrin IX is a dual inhibitor of p53/MDM2 and p53/MDM4 interactions and induces apoptosis in B-cell chronic lymphocytic leukemia cells

artículo científico publicado en 2019

Reactivation of TAp73 tumor suppressor by protoporphyrin IX, a metabolite of aminolevulinic acid, induces apoptosis in 53-deficient cancer cells

artículo científico publicado en 2018

Targeting of p53 and its homolog p73 by protoporphyrin IX

artículo científico publicado en 2010

The Therapeutic Potential of the Restoration of the p53 Protein Family Members in the EGFR-Mutated Lung Cancer

artículo científico publicado en 2022

The Undervalued Avenue to Reinstate Tumor Suppressor Functionality of the p53 Protein Family for Improved Cancer Therapy-Drug Repurposing

scientific article published on 22 September 2020

The p53-mediated cytotoxicity of photodynamic therapy of cancer: recent advances.

scientific article published on 22 July 2008

The p53/MDM2/MDMX-targeted therapies-a clinical synopsis

scientific article published on 17 April 2020

The use of ion mobility mass spectrometry to probe modulation of the structure of p53 and of MDM2 by small molecule inhibitors

artículo científico publicado en 2015

Tumor suppressor Fhit protein interacts with protoporphyrin IX in vitro and enhances the response of HeLa cells to photodynamic therapy.

artículo científico publicado en 2006

[The structure and cellular regulation of p73: their implication in anticancer therapy]

artículo científico publicado en 2010

p53 family members - important messengers in cell death signaling in photodynamic therapy of cancer?

artículo científico publicado en 2015

p53-dependent inhibition of TrxR1 contributes to the tumor-specific induction of apoptosis by RITA.

artículo científico publicado en 2009

p73 tumor suppressor protein: a close relative of p53 not only in structure but also in anti-cancer approach?

scientific article published on 16 February 2010

Lista de obras de

APR-246 reactivates mutant p53 by targeting cysteines 124 and 277.

Aberration of the enzymatic activity of Fhit tumor suppressor protein enhances cancer cell death upon photodynamic therapy similarly to that driven by wild-type Fhit.

Activation of TAp73 and inhibition of TrxR by Verteporfin for improved cancer therapy in mutant pancreatic tumors

Correction to: Reactivation of TAp73 tumor suppressor by protoporphyrin IX, a metabolite of aminolevulinic acid, induces apoptosis in TP53-deficient cancer cells

Correction: APR-246 reactivates mutant p53 by targeting cysteines 124 and 277

Enlightened protein: Fhit tumor suppressor protein structure and function and its role in the toxicity of protoporphyrin IX-mediated photodynamic reaction.

Evaluation of the role of the pharmacological inhibition of Staphylococcus aureus multidrug resistance pumps and the variable levels of the uptake of the sensitizer in the strain-dependent response of Staphylococcus aureus to PPArg(2)-based photodyn

Expression and simple, one-step purification of fragile histidine triad (Fhit) tumor suppressor mutant forms in Escherichia coli and their interaction with protoporphyrin IX.

Induction of apoptosis in HL-60 cells through the ROS-mediated mitochondrial pathway by ramentaceone from Drosera aliciae.

Inhibition of glycolytic enzymes mediated by pharmacologically activated p53: targeting Warburg effect to fight cancer

Pharmacological activation of tumor suppressor, wild-type p53 as a promising strategy to fight cancer

Plumbagin induces apoptosis in Her2-overexpressing breast cancer cells through the mitochondrial-mediated pathway.

Protoporphyrin IX induces apoptosis in HeLa cells prior to photodynamic treatment

Protoporphyrin IX interacts with wild-type p53 protein in vitro and induces cell death of human colon cancer cells in a p53-dependent and -independent manner

Protoporphyrin IX is a dual inhibitor of p53/MDM2 and p53/MDM4 interactions and induces apoptosis in B-cell chronic lymphocytic leukemia cells

Reactivation of TAp73 tumor suppressor by protoporphyrin IX, a metabolite of aminolevulinic acid, induces apoptosis in 53-deficient cancer cells

Targeting of p53 and its homolog p73 by protoporphyrin IX

The Therapeutic Potential of the Restoration of the p53 Protein Family Members in the EGFR-Mutated Lung Cancer

The Undervalued Avenue to Reinstate Tumor Suppressor Functionality of the p53 Protein Family for Improved Cancer Therapy-Drug Repurposing

The p53-mediated cytotoxicity of photodynamic therapy of cancer: recent advances.

The p53/MDM2/MDMX-targeted therapies-a clinical synopsis

The use of ion mobility mass spectrometry to probe modulation of the structure of p53 and of MDM2 by small molecule inhibitors

Tumor suppressor Fhit protein interacts with protoporphyrin IX in vitro and enhances the response of HeLa cells to photodynamic therapy.

[The structure and cellular regulation of p73: their implication in anticancer therapy]

p53 family members - important messengers in cell death signaling in photodynamic therapy of cancer?

p53-dependent inhibition of TrxR1 contributes to the tumor-specific induction of apoptosis by RITA.

p73 tumor suppressor protein: a close relative of p53 not only in structure but also in anti-cancer approach?