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1468. PCV13 Serotype Trends Over Time in Pneumococcal Community Acquired Pneumonia: Which Method(s) Work Best?

2714. Streptococcus pneumoniae Nasopharyngeal Carriage in Canadian Adults Hospitalized with Community-Acquired Pneumonia from 2010 to 2017

2715. Pneumococcal Community-Acquired Pneumonia Attributed to PCV13 Serotypes in Hospitalized Adults: Comparison of the 50–64 and 65+ Age Groups

97. Competition Experiments for the Baloxavir-Resistant I38T Influenza A Mutant

992. 2016–2017 Influenza Burden of Disease and End-of-Season Influenza Vaccine Effectiveness (VE) Estimates for Preventing Influenza-Related Hospitalization Among Canadian Adults: An Analysis From the Canadian Immunization Research Network (CIRN) S

article

A Cluster of Three Cases of Hantavirus Pulmonary Syndrome among Canadian Military Personnel

artículo científico publicado en 2016

A Review of Clinical Influenza A and B Infections With Reduced Susceptibility to Both Oseltamivir and Zanamivir

artículo científico publicado en 2017

A novel neuraminidase deletion mutation conferring resistance to oseltamivir in clinical influenza A/H3N2 virus

artículo científico publicado en 2009

A reverse genetics study of resistance to neuraminidase inhibitors in an influenza A/H1N1 virus.

artículo científico publicado en 2004

A review of influenza vaccine immunogenicity and efficacy in HIV-infected adults

artículo científico publicado en 2008

A trial of valganciclovir prophylaxis for cytomegalovirus prevention in lung transplant recipients.

artículo científico publicado en 2005

Absence of cytomegalovirus-resistance mutations after valganciclovir prophylaxis, in a prospective multicenter study of solid-organ transplant recipients

artículo científico publicado en 2004

Activity of the neuraminidase inhibitor A-315675 against oseltamivir-resistant influenza neuraminidases of N1 and N2 subtypes

artículo científico publicado en 2007

Activity of the oral neuraminidase inhibitor A-322278 against the oseltamivir-resistant H274Y (A/H1N1) influenza virus mutant in mice

artículo científico publicado en 2008

Adjuvant effect of the human metapneumovirus (HMPV) matrix protein in HMPV subunit vaccines

artículo científico publicado en 2014

Adjuvanted inactivated influenza A(H3N2) vaccines induce stronger immunogenicity in mice and confer higher protection in ferrets than unadjuvanted inactivated vaccines

artículo científico publicado en 2014

Age-stratified burden of pneumococcal community acquired pneumonia in hospitalised Canadian adults from 2010 to 2015

scientific article published on 01 March 2020

Amphipathic DNA polymers are candidate vaginal microbicides and block herpes simplex virus binding, entry and viral gene expression.

artículo científico

Amphipathic DNA polymers exhibit antiherpetic activity in vitro and in vivo

artículo científico publicado en 2008

An Early Microglial Response is Needed to Efficiently Control Herpes Simplex Virus Encephalitis

artículo científico publicado en 2020

Analysis of HHV-6 mutations in solid organ transplant recipients at the onset of cytomegalovirus disease and following treatment with intravenous ganciclovir or oral valganciclovir

artículo científico publicado en 2013

Analysis of cytomegalovirus DNA polymerase (UL54) mutations in solid organ transplant patients receiving valganciclovir or ganciclovir prophylaxis

artículo científico publicado en 2005

Analysis of replication kinetics of the human metapneumovirus in different cell lines by real-time PCR

artículo científico publicado en 2005

Antibiotic use in children is not influenced by the result of rapid antigen detection test for the respiratory syncytial virus

artículo científico publicado en 2007

Antibody persistence and response to 2010-2011 trivalent influenza vaccine one year after a single dose of 2009 AS03-adjuvanted pandemic H1N1 vaccine in children

artículo científico publicado en 2011

Antiviral Agents in Development for Zika Virus Infections

scientific article published on 29 June 2019

Antiviral drug resistance in herpesviruses other than cytomegalovirus

artículo científico

Antiviral resistance in herpes simplex virus and varicella-zoster virus infections: diagnosis and management

artículo científico publicado en 2016

Artesunate demonstrates in vitro synergism with several antiviral agents against human cytomegalovirus

artículo científico publicado en 2016

Assessing the in vitro fitness of an oseltamivir-resistant seasonal A/H1N1 influenza strain using a mathematical model

artículo científico publicado en 2011

Association between the 2008-09 seasonal influenza vaccine and pandemic H1N1 illness during Spring-Summer 2009: four observational studies from Canada

artículo científico publicado en 2010

Both Cerebral and Hematopoietic Deficiencies in CCR2 Result in Uncontrolled Herpes Simplex Virus Infection of the Central Nervous System in Mice

artículo científico publicado en 2016

Both IRF3 and especially IRF7 play a key role to orchestrate an effective cerebral inflammatory response in a mouse model of herpes simplex virus encephalitis

artículo científico publicado en 2018

Both TRIF and IPS-1 adaptor proteins contribute to the cerebral innate immune response against herpes simplex virus 1 infection

artículo científico publicado en 2013

Burden of vaccine-preventable pneumococcal disease in hospitalized adults: A Canadian Immunization Research Network (CIRN) Serious Outcomes Surveillance (SOS) network study

artículo científico publicado en 2017

CMV seropositivity is associated with increased microbial translocation in people living with HIV and uninfected controls

scientific article published on 14 October 2019

Canadian consensus guidelines for the management of cytomegalovirus disease in HIV/AIDS.

artículo científico publicado en 2004

Cell Culture Systems To Study Human Herpesvirus 6A/B Chromosomal Integration.

artículo científico publicado en 2017

Characterization of 2 influenza A(H3N2) clinical isolates with reduced susceptibility to neuraminidase inhibitors due to mutations in the hemagglutinin gene

artículo científico publicado en 2002

Characterization of cellular transcriptomic signatures induced by different respiratory viruses in human reconstituted airway epithelia

scientific article published on 07 August 2019

Characterization of contemporary influenza B recombinant viruses harboring mutations of reduced susceptibility to baloxavir marboxil, in vitro and in mice

artículo científico publicado en 2020

Characterization of drug-resistant influenza virus A(H1N1) and A(H3N2) variants selected in vitro with laninamivir

artículo científico publicado en 2014

Characterization of drug-resistant recombinant influenza A/H1N1 viruses selected in vitro with peramivir and zanamivir

artículo científico publicado en 2006

Characterization of human cytomegalovirus (HCMV) UL97 mutations found in a valganciclovir/oral ganciclovir prophylactic trial by use of a bacterial artificial chromosome containing the HCMV genome

artículo científico publicado en 2006

Characterization of human metapneumoviruses isolated from patients in North America

artículo científico publicado en 2002

Characterization of multidrug-resistant influenza A/H3N2 viruses shed during 1 year by an immunocompromised child

artículo científico publicado en 2006

Characterization of multiple cytomegalovirus drug resistance mutations detected in a hematopoietic stem cell transplant recipient by recombinant phenotyping

artículo científico publicado en 2014

Clinical development of letermovir and maribavir: Overview of human cytomegalovirus drug resistance

scientific article published on 25 January 2019

Combination Therapy with Oseltamivir and Favipiravir Delays Mortality but Does Not Prevent Oseltamivir Resistance in Immunodeficient Mice Infected with Pandemic A(H1N1) Influenza Virus

artículo científico publicado en 2018

Comparative evaluation of real-time PCR assays for detection of the human metapneumovirus

artículo científico publicado en 2003

Comparative evaluation of three serological methods for detection of human herpesvirus 8-specific antibodies in Canadian allogeneic stem cell transplant recipients

artículo científico publicado en 2004

Comparison of Automated Microarray Detection with Real-Time PCR Assays for Detection of Respiratory Viruses in Specimens Obtained from Children

artículo científico publicado en 2010

Comparison of automated microarray detection with real-time PCR assays for detection of respiratory viruses in specimens obtained from children

artículo científico publicado en 2009

Comparison of early and recent influenza A(H1N1)pdm09 isolates harboring or not the H275Y neuraminidase mutation, in vitro and in animal models

artículo científico publicado en 2018

Comparison of pandemic and seasonal influenza in the pediatric emergency department

artículo científico publicado en 2011

Comparison of risk factors for human metapneumovirus and respiratory syncytial virus disease severity in young children.

artículo científico publicado en 2012

Comparison of the inhibition of human metapneumovirus and respiratory syncytial virus by ribavirin and immune serum globulin in vitro ⬇️

artículo científico publicado el 1 de septiembre de 2003

Compartmentalization of a Multidrug-Resistant Cytomegalovirus UL54 Mutant in a Stem Cell Transplant Recipient with Encephalitis

artículo científico publicado en 2019

Contagious period for pandemic (H1N1) 2009.

artículo científico publicado en 2010

Contrasting effects of W781V and W780V mutations in helix N of herpes simplex virus 1 and human cytomegalovirus DNA polymerases on antiviral drug susceptibility

artículo científico publicado en 2015

Contrasting effects on ganciclovir susceptibility and replicative capacity of two mutations at codon 466 of the human cytomegalovirus UL97 gene ⬇️

artículo científico publicado el 16 de septiembre de 2010

Cross-lineage influenza B and heterologous influenza A antibody responses in vaccinated mice: immunologic interactions and B/Yamagata dominance

artículo científico publicado en 2012

Cross-reactive and vaccine-induced antibody to an emerging swine-origin variant of influenza A virus subtype H3N2 (H3N2v).

artículo científico publicado en 2012

Cytomegalovirus (CMV) glycoprotein B genotypes and response to antiviral therapy, in solid-organ-transplant recipients with CMV disease

artículo científico publicado en 2003

Cytomegalovirus (CMV) virus load kinetics to predict recurrent disease in solid-organ transplant patients with CMV disease

artículo científico publicado en 2002

Cytomegalovirus quantification in plasma with Abbott RealTime CMV and Roche Cobas Amplicor CMV assays

artículo científico publicado en 2015

Cytomegalovirus resistance in solid organ transplant recipients treated with intravenous ganciclovir or oral valganciclovir

artículo científico publicado en 2009

Cytomegalovirus ventriculoencephalitis in a peripheral blood stem cell transplant recipient

artículo científico publicado en 2006

DNA vaccination protects mice against Zika virus-induced damage to the testes

artículo científico publicado en 2017

Delayed but not early glucocorticoid treatment protects the host during experimental herpes simplex virus encephalitis in mice

artículo científico publicado en 2007

Design and Validation with Influenza A Virus of an Aerosol Transmission Chamber for Ferrets

article

Design considerations in building in silico equivalents of common experimental influenza virus assays.

artículo científico publicado en 2011

Detection and management of antiviral resistance for influenza viruses

artículo científico publicado en 2013

Detection of human metapneumovirus antigens in nasopharyngeal aspirates using an enzyme immunoassay

artículo científico publicado en 2008

Development and validation of an enzyme-linked immunosorbent assay for human metapneumovirus serology based on a recombinant viral protein

artículo científico publicado en 2005

Development of a serological assay based on a synthetic peptide selected from the VP0 capsid protein for detection of human parechoviruses

artículo científico publicado en 2007

Development of a universal influenza A vaccine based on the M2e peptide fused to the papaya mosaic virus (PapMV) vaccine platform.

artículo científico publicado en 2008

Diagnosis of herpesvirus infections of the central nervous system.

artículo científico publicado en 2004

Discordant phenotypes and genotypes of cytomegalovirus (CMV) in patients with AIDS and relapsing CMV retinitis

artículo científico publicado en 2003

Disseminated herpes simplex virus type 1 primary infection in a healthy individual

artículo científico publicado en 2009

Distribution and clinical impact of human respiratory syncytial virus genotypes in hospitalized children over 2 winter seasons

artículo científico publicado en 2005

Divergent evolution of hemagglutinin and neuraminidase genes in recent influenza A:H3N2 viruses isolated in Canada

artículo científico publicado en 2002

Droplet Digital PCR and Immunohistochemistry Techniques to Detect Zika Virus in the Central Nervous System of Mice

scientific article published on 01 January 2020

Droplet digital PCR to investigate quasi-species at codons 119 and 275 of the A(H1N1)pdm09 neuraminidase during zanamivir and oseltamivir therapies

artículo científico publicado en 2016

Drug Susceptibility and Replicative Capacity of Multi-Drug Resistant Recombinant Human Cytomegalovirus Harboring Mutations in UL56 and UL54 Genes

artículo científico publicado en 2017

Drug resistance patterns of recombinant herpes simplex virus DNA polymerase mutants generated with a set of overlapping cosmids and plasmids

artículo científico publicado en 2003

E119D Neuraminidase Mutation Conferring Pan-Resistance to Neuraminidase Inhibitors in an A(H1N1)pdm09 Isolate From a Stem-Cell Transplant Recipient

artículo científico publicado en 2015

Effect of in vitro syncytium formation on the severity of human metapneumovirus disease in a murine model

artículo científico publicado en 2015

Effect of pretreatment with toll-like receptor agonists in a mouse model of herpes simplex virus type 1 encephalitis

artículo científico publicado en 2008

Effect of ribavirin and glucocorticoid treatment in a mouse model of human metapneumovirus infection

artículo científico publicado en 2006

Effect of the neuraminidase mutation H274Y conferring resistance to oseltamivir on the replicative capacity and virulence of old and recent human influenza A(H1N1) viruses

artículo científico publicado en 2010

Effectiveness of Influenza Vaccination on Hospitalizations and Risk Factors for Severe Outcomes in Hospitalized Patients With COPD

artículo científico publicado en 2019

Effects of Different Drug Combinations in Immunodeficient Mice Infected with an Influenza A/H3N2 Virus

artículo científico publicado en 2020

Effects of different adjuvants in the context of intramuscular and intranasal routes on humoral and cellular immune responses induced by detergent-split A/H3N2 influenza vaccines in mice

artículo científico publicado en 2011

Emergence of an oseltamivir-resistant influenza A/H3N2 virus in an elderly patient receiving a suboptimal dose of antiviral prophylaxis

artículo científico publicado en 2013

Emergence of oseltamivir-resistant pandemic H1N1 virus during prophylaxis

artículo científico publicado en 2009

Engineering of Live Chimeric Vaccines against Human Metapneumovirus

artículo científico publicado en 2020

Enhanced lung disease and Th2 response following human metapneumovirus infection in mice immunized with the inactivated virus

artículo científico publicado en 2007

Epidemiology of Influenza Viruses in Canada over the 2011–2012 to 2013–2014 Seasons: A Study from the Serious Outcomes Surveillance (SOS) Network of the Canadian Immunization Research Network (CIRN).

artículo científico publicado en 2017

Epitope mapping of the 2009 pandemic and the A/Brisbane/59/2007 seasonal (H1N1) influenza virus haemagglutinins using mAbs and escape mutants.

artículo científico publicado en 2014

Estradiol is required for a proper immune response to bacterial and viral pathogens in the female brain

artículo científico publicado en 2005

Evaluation of Epstein-Barr virus, human herpesvirus 6 (HHV-6), and HHV-8 antiviral drug susceptibilities by use of real-time-PCR-based assays

artículo científico publicado en 2013

Evaluation of anticoagulant agents for the treatment of human metapneumovirus infection in mice

artículo científico publicado en 2018

Evaluation of pre- and post-fusion Human metapneumovirus F proteins as subunit vaccine candidates in mice

scientific article published on 29 January 2020

Evaluation of recombinant 2009 pandemic influenza A (H1N1) viruses harboring zanamivir resistance mutations in mice and ferrets.

artículo científico publicado en 2013

Evaluation of serological diagnostic methods for the 2009 pandemic influenza A (H1N1) virus

artículo científico publicado en 2011

Evaluation of susceptibility of human herpesvirus 8 to antiviral drugs by quantitative real-time PCR.

artículo científico publicado en 2003

Evolution of oseltamivir resistance mutations in Influenza A(H1N1) and A(H3N2) viruses during selection in experimentally infected mice.

artículo científico publicado en 2014

Evolution of surface and nonstructural-1 genes of influenza B viruses isolated in the Province of Québec, Canada, during the 1998-2001 period

artículo científico publicado el 1 de octubre de 2003

Fitness of influenza A and B viruses with reduced susceptibility to baloxavir: A mini-review

artículo científico publicado en 2020

Frailty Hinders Recovery From Acute Respiratory Illness in Older Adults

Frailty Hinders Recovery From Influenza and Acute Respiratory Illness in Older Adults

artículo científico publicado en 2020

Generation and characterization of recombinant influenza A (H1N1) viruses harboring amantadine resistance mutations

artículo científico publicado en 2005

Generation and characterization of recombinant pandemic influenza A(H1N1) viruses resistant to neuraminidase inhibitors

artículo científico publicado en 2011

Genetic diversity and molecular evolution of the major human metapneumovirus surface glycoproteins over a decade.

artículo científico publicado en 2013

Genetic diversity between human metapneumovirus subgroups ⬇️

artículo científico publicado el 10 de octubre de 2003

Global genetic diversity of human metapneumovirus fusion gene

artículo científico publicado en 2004

Herpes simplex encephalitis in adult patients with MASP-2 deficiency

artículo científico publicado en 2019

Herpes simplex virus isolates with reduced adefovir susceptibility selected in vivo by foscarnet therapy

artículo científico publicado en 2002

Herpesvirus DNA polymerases: Structures, functions and inhibitors

artículo científico publicado en 2017

Heterosubtypic protection conferred by the human monoclonal antibody PN-SIA28 against influenza A virus lethal infections in mice

artículo científico publicado en 2015

Host and viral factors affecting clinical performance of a rapid diagnostic test for respiratory syncytial virus in hospitalized children

artículo científico publicado en 2013

Household transmission of the 2009 pandemic A/H1N1 influenza virus: elevated laboratory‐confirmed secondary attack rates and evidence of asymptomatic infections.

artículo científico publicado en 2010

Human Respiratory Syncytial Virus-induced immune signature of infection revealed by transcriptome analysis of clinical pediatric nasopharyngeal swab samples

artículo científico publicado en 2020

Human bocavirus infections in hospitalized children and adults

artículo científico publicado en 2008

Human metapneumovirus activates NOD-like receptor protein 3 inflammasome via its small hydrophobic protein which plays a detrimental role during infection in mice

artículo científico publicado en 2019

Human metapneumovirus genetic variability, South Africa

artículo científico publicado en 2005

Human metapneumovirus infection in immunocompromised child

artículo científico publicado en 2008

Human metapneumovirus infection induces long-term pulmonary inflammation associated with airway obstruction and hyperresponsiveness in mice.

artículo científico publicado en 2006

Human metapneumovirus infections in hospitalized children

artículo científico publicado en 2003

Human metapneumovirus viral load is an important risk factor for disease severity in young children

artículo científico publicado en 2014

Human metapneumovirus, Peru

artículo científico publicado en 2006

Human metapneumovirus-associated lower respiratory tract infections among hospitalized human immunodeficiency virus type 1 (HIV-1)-infected and HIV-1-uninfected African infants

artículo científico publicado en 2003

Human metapneumovirus.

artículo científico publicado en 2007

Human metapneumovirus: a new player among respiratory viruses

artículo científico publicado en 2004

Human metapneumovirus: a ubiquitous and long-standing respiratory pathogen

artículo científico publicado en 2005

Human metapneumovirus: enhanced pulmonary disease in cotton rats immunized with formalin-inactivated virus vaccine and challenged.

artículo científico publicado en 2007

Human parainfluenza type 4 infections, Canada

artículo científico publicado en 2006

Human parechovirus 3 and neonatal infections

artículo científico publicado en 2005

Human parechovirus causes encephalitis with white matter injury in neonates

artículo científico publicado en 2008

Human parechovirus types 1, 2 and 3 infections in Canada

artículo científico publicado en 2006

Human respiratory syncytial virus and other viral infections in infants receiving palivizumab

artículo científico publicado en 2008

Hydroxyurea enhances the activity of acyclovir and cidofovir against herpes simplex virus type 1 resistant strains harboring mutations in the thymidine kinase and/or the DNA polymerase genes

artículo científico publicado en 2007

Hypersusceptibility of Human Cytomegalovirus to Foscarnet Induced by Mutations in Helices K and P of the Viral DNA Polymerase

artículo científico publicado en 2020

Identification and evaluation of a highly effective fusion inhibitor for human metapneumovirus

artículo científico publicado en 2007

Immunogenicity and tolerability of an inactivated and adjuvanted pandemic H1N1 influenza vaccine, in HIV-1-infected patients

artículo científico publicado en 2010

Immunogenicity is not improved by increased antigen dose or booster dosing of seasonal influenza vaccine in a randomized trial of HIV infected adults

artículo científico publicado en 2011

Immunomodulatory Strategies in Herpes Simplex Virus Encephalitis

artículo científico publicado en 2020

Impact of Antivirals in the Prevention of Serious Outcomes Associated with Influenza in Hospitalized Canadian Adults: A Pooled Analysis from the Serious Outcomes Surveillance (SOS) Network of the Canadian Immunization Research Network (CIRN).

artículo científico publicado en 2017

Impact of Prior Season Influenza Vaccination on Seasonal Influenza Vaccine Effectiveness: An Analysis over Four Consecutive Seasons from the Serious Outcomes Surveillance (SOS) Network of the Canadian Immunization Research Network (CIRN).

artículo científico publicado en 2017

Impact of R152K and R368K neuraminidase catalytic substitutions on in vitro properties and virulence of recombinant A(H1N1)pdm09 viruses.

artículo científico publicado en 2018

Impact of a large deletion in the neuraminidase protein identified in a laninamivir-selected influenza A/Brisbane/10/2007 (H3N2) variant on viral fitness in vitro and in ferrets

artículo científico publicado en 2015

Impact of deficiency in CCR2 and CX3CR1 receptors on monocytes trafficking in herpes simplex virus encephalitis

artículo científico publicado en 2012

Impact of mutations at residue I223 of the neuraminidase protein on the resistance profile, replication level, and virulence of the 2009 pandemic influenza virus

artículo científico publicado en 2011

Impact of neuraminidase mutations conferring influenza resistance to neuraminidase inhibitors in the N1 and N2 genetic backgrounds.

artículo científico publicado en 2006

Impact of potential permissive neuraminidase mutations on viral fitness of the H275Y oseltamivir-resistant influenza A(H1N1)pdm09 virus in vitro, in mice and in ferrets.

artículo científico publicado en 2013

Impact of the Baloxavir-Resistant Polymerase Acid I38T Substitution on the Fitness of Contemporary Influenza A(H1N1)pdm09 and A(H3N2) Strains

scientific article published on 01 January 2020

Impact of the H275Y and I223V Mutations in the Neuraminidase of the 2009 Pandemic Influenza Virus In Vitro and Evaluating Experimental Reproducibility

artículo científico publicado en 2015

Importance of viral and bacterial infections in chronic obstructive pulmonary disease exacerbations

artículo científico publicado en 2009

In Vitro Combinations of Baloxavir Acid and Other Inhibitors against Seasonal Influenza A Viruses

scientific article published on 08 October 2020

In Vitro Properties and Virulence of Contemporary Recombinant Influenza B Viruses Harboring Mutations of Cross-Resistance to Neuraminidase Inhibitors

artículo científico publicado en 2018

In vitro activity of letermovir against human cytomegalovirus isolates with different drug susceptibility phenotypes

artículo científico publicado en 2022

In vitro and in vivo evidence of a potential A(H1N1)pdm09 antigenic drift mediated by escape mutations in the haemagglutinin Sa antigenic site

artículo científico publicado en 2017

In vitro susceptibility of geographically and temporally distinct zika viruses to favipiravir and ribavirin

artículo científico publicado en 2017

Incidence and characterization of cytomegalovirus resistance mutations among pediatric solid organ transplant patients who received valganciclovir prophylaxis

artículo científico publicado en 2010

Incidence of cytomegalovirus UL97 and UL54 amino acid substitutions detected after 100 or 200 days of valganciclovir prophylaxis

artículo científico publicado en 2012

Infection with human metapneumovirus predisposes mice to severe pneumococcal pneumonia

artículo científico publicado en 2008

Infections by human coronavirus-NL in hospitalized children

artículo científico publicado en 2005

Infiltration Pattern of Blood Monocytes into the Central Nervous System during Experimental Herpes Simplex Virus Encephalitis

artículo científico publicado en 2015

Influenza drug resistance

artículo científico

Influenza vaccine effectiveness against influenza-related hospitalization during a season with mixed outbreaks of four influenza viruses: a test-negative case-control study in adults in Canada

artículo científico publicado en 2017

Influenza vaccine effectiveness to prevent influenza-related hospitalizations and serious outcomes in Canadian adults over the 2011/12 through 2013/14 influenza seasons: A pooled analysis from the Canadian Immunization Research Network (CIRN) Seriou

artículo científico publicado en 2018

Influenza virus activates human immunodeficiency virus type-1 gene expression in human CD4-expressing T cells through an NF-kappaB-dependent pathway

artículo científico publicado en 2005

Influenza virus epidemiology: a permanent vaccine challenge

artículo científico publicado en 2019

Influenza virus resistance to neuraminidase inhibitors.

artículo científico publicado en 2013

Influenza virus shedding: excretion patterns and effects of antiviral treatment

artículo científico publicado en 2009

Influenza virus susceptibility and resistance to oseltamivir.

artículo científico publicado en 2007

Influenzavirus infection is a primary cause of febrile respiratory illness in HIV-infected adults, despite vaccination

artículo científico publicado en 2007

Inhibition of human metapneumovirus replication by small interfering RNA.

artículo científico publicado en 2008

Innate immune response during herpes simplex virus encephalitis and development of immunomodulatory strategies

artículo científico

Intrahost dynamics of antiviral resistance in influenza A virus reflect complex patterns of segment linkage, reassortment, and natural selection

artículo científico publicado en 2015

Intranasal herpes simplex virus type 2 inoculation causes a profound thymidine kinase dependent cerebral inflammatory response in the mouse hindbrain

artículo científico publicado en 2002

Long-term impairment of Streptococcus pneumoniae lung clearance is observed after initial infection with influenza A virus but not human metapneumovirus in mice

artículo científico publicado en 2011

Longitudinal evaluation of herpes simplex virus DNA load during episodes of herpes labialis

artículo científico publicado en 2006

Low systemic ganciclovir exposure and preemptive treatment failure of cytomegalovirus reactivation in a transplanted child.

artículo científico publicado en 2011

Management and prevention of herpes zoster: A Canadian perspective

artículo científico publicado en 2010

Mapping and characterization of the primary and anamnestic H-2(d)-restricted cytotoxic T-lymphocyte response in mice against human metapneumovirus

artículo científico publicado en 2007

Microglia are involved in phagocytosis and extracellular digestion during Zika virus encephalitis in young adult immunodeficient mice

artículo científico publicado en 2021

Modified cyclodextrins as broad-spectrum antivirals

scientific article published on 29 January 2020

Modulation of TLR9 response in a mouse model of herpes simplex virus encephalitis

artículo científico publicado en 2012

Modulation of protease activated receptor 1 influences human metapneumovirus disease severity in a mouse model

artículo científico publicado en 2013

Molecular and antigenic evolution of human influenza A/H3N2 viruses in Quebec, Canada, 2009-2011.

artículo científico publicado en 2011

Molecular and epidemiologic investigation of a rhinovirus outbreak in a neonatal intensive care unit

scientific article published on 05 December 2018

Molecular characterization of a Canadian human parechovirus (HPeV)-3 isolate and its relationship to other HPeVs

artículo científico publicado en 2005

Molecular characterization of viruses from clinical respiratory samples producing unidentified cytopathic effects in cell culture

artículo científico publicado en 2009

Molecular evolution of respiratory syncytial virus fusion gene, Canada, 2006-2010.

artículo científico publicado en 2012

Molecular pathway of influenza pan-neuraminidase inhibitor resistance in an immunocompromised patient

artículo científico publicado en 2020

Multi-year study of human metapneumovirus infection at a large US Midwestern Medical Referral Center

artículo científico publicado en 2006

Multiplex real-time PCR assay for detection of influenza and human respiratory syncytial viruses.

artículo científico publicado en 2004

Mutations in the fusion protein heptad repeat domains of human metapneumovirus impact on the formation of syncytia

artículo científico publicado en 2017

Neuraminidase-inhibitor resistance testing for pandemic influenza A (H1N1) 2009 in Ontario, Canada

artículo científico publicado en 2011

Neurovirulence and latency of drug-resistant clinical herpes simplex viruses in animal models

artículo científico publicado en 2010

New Saffold cardioviruses in 3 children, Canada

artículo científico publicado en 2008

Novel Method Based on Real-Time Cell Analysis for Drug Susceptibility Testing of Herpes Simplex Virus and Human Cytomegalovirus

artículo científico publicado en 2016

Novel antiviral compounds and combination therapy for influenza viruses

scientific article published on 01 December 2019

Novel antiviral compounds and combination therapy for influenza viruses

artículo científico publicado en 2019

Novel calixarene-based surfactant enables low dose split inactivated vaccine protection against influenza infection

scientific article published on 18 October 2019

Novel method based on "en passant" mutagenesis coupled with a gaussia luciferase reporter assay for studying the combined effects of human cytomegalovirus mutations

artículo científico publicado en 2013

OVX836 a recombinant nucleoprotein vaccine inducing cellular responses and protective efficacy against multiple influenza A subtypes

article

Opposite effect of two cytomegalovirus DNA polymerase mutations on replicative capacity and polymerase activity

artículo científico publicado en 2010

Optimization of Droplet Digital PCR from RNA and DNA extracts with direct comparison to RT-qPCR: Clinical implications for quantification of Oseltamivir-resistant subpopulations.

artículo científico publicado en 2015

Oseltamivir-resistant pandemic A/H1N1 virus is as virulent as its wild-type counterpart in mice and ferrets

artículo científico publicado en 2010

Oseltamivir-zanamivir combination therapy is not superior to zanamivir monotherapy in mice infected with influenza A(H3N2) and A(H1N1)pdm09 viruses.

artículo científico publicado en 2014

Parenteral peramivir treatment for Oseltamivir-resistant 2009 pandemic influenza A H1N1 viruses

artículo científico publicado en 2011

Pathogenesis of human metapneumovirus lung infection in BALB/c mice and cotton rats

artículo científico publicado en 2005

Pathogenicity and response to topical antiviral therapy in a murine model of acyclovir-sensitive and acyclovir-resistant herpes simplex viruses isolated from the same patient

artículo científico publicado en 2006

Peramivir susceptibilities of recombinant influenza A and B variants selected with various neuraminidase inhibitors

artículo científico publicado en 2017

Permissive changes in the neuraminidase play a dominant role in improving the viral fitness of oseltamivir-resistant seasonal influenza A(H1N1) strains.

artículo científico publicado en 2014

Phenotypic evaluation of previously uncharacterized cytomegalovirus DNA polymerase sequence variants detected in a valganciclovir treatment trial

artículo científico publicado en 2013

Plastic polymers for efficient DNA microarray hybridization: application to microbiological diagnostics

artículo científico publicado en 2008

Predominant role of IPS-1 over TRIF adaptor proteins in early innate immune response against Zika virus in mice

artículo científico publicado en 2018

Presence of oseltamivir-resistant pandemic A/H1N1 minor variants before drug therapy with subsequent selection and transmission.

artículo científico publicado en 2012

Prolonged excretion of amantadine-resistant influenza a virus quasi species after cessation of antiviral therapy in an immunocompromised patient

artículo científico publicado en 2002

Prophylactic activity of intramuscular peramivir in mice infected with a recombinant influenza A/WSN/33 (H1N1) virus containing the H274Y neuraminidase mutation

artículo científico publicado en 2010

Prophylactic and therapeutic benefits of a monoclonal antibody against the fusion protein of human metapneumovirus in a mouse model.

artículo científico publicado en 2010

Protease-activated receptor 1 inhibition protects mice against thrombin-dependent respiratory syncytial virus and human metapneumovirus infections

artículo científico publicado en 2017

Protective role of CX3CR1 signalling in resident cells of the central nervous system during experimental herpes simplex virus encephalitis

artículo científico publicado en 2016

Quantification of human herpesvirus 8 by real-time PCR in blood fractions of AIDS patients with Kaposi's sarcoma and multicentric Castleman's disease

artículo científico publicado en 2002

Quantification of the influenza virus load by real-time polymerase chain reaction in nasopharyngeal swabs of patients treated with oseltamivir

artículo científico publicado en 2003

Randomized controlled ferret study to assess the direct impact of 2008-09 trivalent inactivated influenza vaccine on A(H1N1)pdm09 disease risk

artículo científico publicado en 2014

Recent developments with live-attenuated recombinant paramyxovirus vaccines

artículo científico

Recombinant Phenotyping of Cytomegalovirus Sequence Variants Detected After 200 or 100 Days of Valganciclovir Prophylaxis ⬇️

artículo científico publicado el 27 de diciembre de 2010

Recombinant phenotyping of cytomegalovirus UL54 mutations that emerged during cell passages in the presence of either ganciclovir or foscarnet

artículo científico publicado en 2011

Reduced Susceptibility to Neuraminidase Inhibitors in Influenza B Isolate, Canada

article

Reduced airborne transmission of oseltamivir-resistant pandemic A/H1N1 virus in ferrets

artículo científico publicado en 2011

Reply to "Calibration technologies for correct determination of Epstein-Barr Virus, human herpesvirus 6 (HHV-6), and HHV-8 antiviral drug susceptibilities by use of real-time-PCR-based assays".

artículo científico publicado en 2013

Repurposing of Drugs as Novel Influenza Inhibitors From Clinical Gene Expression Infection Signatures

article

Resistance of herpes simplex viruses to nucleoside analogues: mechanisms, prevalence, and management

artículo científico publicado en 2010

Resistance of herpesviruses to antiviral drugs: clinical impacts and molecular mechanisms

artículo científico publicado en 2002

Resource utilization and cost of influenza requiring hospitalization in Canadian adults: A study from the serious outcomes surveillance network of the Canadian Immunization Research Network

artículo científico publicado en 2017

Respiratory tract reinfections by the new human Metapneumovirus in an immunocompromised child

artículo científico publicado en 2002

Risk factors for hospitalization and severe outcomes of 2009 pandemic H1N1 influenza in Quebec, Canada.

artículo científico publicado en 2011

Role of helix P of the human cytomegalovirus DNA polymerase in resistance and hypersusceptibility to the antiviral drug foscarnet

artículo científico publicado en 2006

Role of permissive neuraminidase mutations in influenza A/Brisbane/59/2007-like (H1N1) viruses

artículo científico publicado en 2011

Role of picornaviruses in flu-like illnesses of adults enrolled in an oseltamivir treatment study who had no evidence of influenza virus infection

artículo científico publicado en 2002

Sequence analysis of the N, P, M and F genes of Canadian human metapneumovirus strains.

artículo científico publicado en 2003

Sequence polymorphism of the predicted human metapneumovirus G glycoprotein

artículo científico publicado en 2004

Seroconversion to seasonal influenza viruses after A(H1N1)pdm09 virus infection, Quebec, Canada

artículo científico publicado en 2012

Single-cell transcriptomics of the ventral posterolateral nucleus-enriched thalamic regions from HSV-1-infected mice reveal a novel microglia/microglia-like transcriptional response

artículo científico publicado en 2022

Standardization of Hemagglutination Inhibition Assay for Influenza Serology Allows for High Reproducibility between Laboratories

artículo científico publicado en 2016

Strain-Dependent Impact of G and SH Deletions Provide New Insights for Live-Attenuated HMPV Vaccine Development

scientific article published on 30 October 2019

Streptococcus pneumoniae serotype 3 is masking PCV13-mediated herd immunity in Canadian adults hospitalized with community acquired pneumonia: A study from the Serious Outcomes Surveillance (SOS) Network of the Canadian immunization research Network

artículo científico publicado en 2019

Structural Insight into NS5 of Zika Virus Leading to the Discovery of MTase Inhibitors

artículo científico publicado en 2016

Susceptibility of recent Canadian influenza A and B virus isolates to different neuraminidase inhibitors

artículo científico publicado en 2002

Syncytium formation and HIV-1 replication are both accentuated by purified influenza and virus-associated neuraminidase

artículo científico publicado en 2002

Synergistic PA and HA mutations confer mouse adaptation of a contemporary A/H3N2 influenza virus

artículo científico publicado en 2019

Systematic review of influenza resistance to the neuraminidase inhibitors

artículo científico publicado en 2011

Targeted Proteomics of Human Metapneumovirus in Clinical Samples and Viral Cultures.

artículo científico publicado en 2015

The 2009 pandemic H1N1 D222G hemagglutinin mutation alters receptor specificity and increases virulence in mice but not in ferrets

artículo científico publicado en 2011

The E119D neuraminidase mutation identified in a multidrug-resistant influenza A(H1N1)pdm09 isolate severely alters viral fitness in vitro and in animal models

artículo científico publicado en 2016

The H275Y neuraminidase mutation of the pandemic A/H1N1 influenza virus lengthens the eclipse phase and reduces viral output of infected cells, potentially compromising fitness in ferrets.

artículo científico publicado en 2012

The I222V neuraminidase mutation has a compensatory role in replication of an oseltamivir-resistant influenza virus A/H3N2 E119V mutant

artículo científico publicado en 2010

The I427T neuraminidase (NA) substitution, located outside the NA active site of an influenza A(H1N1)pdm09 variant with reduced susceptibility to NA inhibitors, alters NA properties and impairs viral fitness.

artículo científico publicado en 2016

The Importance of Frailty in the Assessment of Influenza Vaccine Effectiveness Against Influenza-Related Hospitalization in Elderly People

article

The Nonstructural NS1 Protein of Influenza Viruses Modulates TP53 Splicing through Host Factor CPSF4

scientific article published on 21 March 2019

The Val430Ile neuraminidase (NA) substitution, identified in influenza B virus isolates, impacts the catalytic 116Arg residue causing reduced susceptibility to NA inhibitors

scientific article published on 16 July 2019

The combination of oseltamivir with azithromycin does not show additional benefits over oseltamivir monotherapy in mice infected with influenza A(H1N1)pdm2009 virus.

artículo científico publicado en 2017

The combination of valacyclovir with an anti-TNF alpha antibody increases survival rate compared to antiviral therapy alone in a murine model of herpes simplex virus encephalitis

artículo científico publicado en 2013

The distinguishing features of human metapneumovirus and respiratory syncytial virus

artículo científico publicado en 2010

The need for validation of statistical methods for estimating respiratory virus-attributable hospitalization

artículo científico publicado en 2009

The prophylactic administration of a monoclonal antibody against human metapneumovirus attenuates viral disease and airways hyperresponsiveness in mice

scientific article published on 01 January 2008

The quest for a nanoparticle-based vaccine inducing broad protection to influenza viruses

artículo científico publicado en 2018

The recruitment of peripheral blood leukocytes to the brain is delayed in susceptible BALB/c compared to resistant C57BL/6 mice during herpes simplex virus encephalitis

scientific article published on 13 February 2019

Therapeutic activity of intramuscular peramivir in mice infected with a recombinant influenza A/WSN/33 (H1N1) virus containing the H275Y neuraminidase mutation

artículo científico publicado en 2012

Three-dimensional modeling of cytomegalovirus DNA polymerase and preliminary analysis of drug resistance

artículo científico publicado en 2006

Thymidine kinase mutations conferring acyclovir resistance in herpes simplex type 1 recombinant viruses

artículo científico publicado en 2006

Treatment of respiratory virus infections

artículo científico publicado en 2006

Tumor necrosis factor-alpha and interleukin-1 beta play a critical role in the resistance against lethal herpes simplex virus encephalitis

artículo científico publicado en 2007

Valacyclovir combined with artesunate or rapamycin improves the outcome of herpes simplex virus encephalitis in mice compared to antiviral therapy alone

artículo científico publicado en 2015

Viral pathogens including human metapneumovirus are the primary cause of febrile respiratory illness in HIV-infected adults receiving antiretroviral therapy

artículo científico publicado en 2010

Virological features and clinical manifestations associated with human metapneumovirus: a new paramyxovirus responsible for acute respiratory-tract infections in all age groups

artículo científico publicado en 2002

Virus-like particle vaccine induces cross-protection against human metapneumovirus infections in mice

artículo científico publicado en 2013

WU polyomavirus in children, Canada

artículo científico publicado en 2007

Whole-genome characterization and genotyping of global WU polyomavirus strains

artículo científico publicado en 2010

Zika-Induced Male Infertility in Mice Is Potentially Reversible and Preventable by Deoxyribonucleic Acid Immunization

article

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