Lista de obras -

A bivalent chromatin structure marks key developmental genes in embryonic stem cells

artículo científico publicado en 2006

A distant trophoblast-specific enhancer controls HLA-G expression at the maternal-fetal interface

artículo científico publicado en 2016

A human-specific gene in microglia.

artículo científico publicado en 2005

A second fatty acid amide hydrolase with variable distribution among placental mammals

artículo científico publicado en 2006

A unique regulatory phase of DNA methylation in the early mammalian embryo ⬇️

artículo científico publicado el 28 de marzo de 2012

Aligning Single-Cell Developmental and Reprogramming Trajectories Identifies Molecular Determinants of Myogenic Reprogramming Outcome

artículo científico publicado en 2018

Altered chromatin occupancy of master regulators underlies evolutionary divergence in the transcriptional landscape of erythroid differentiation

artículo científico publicado en 2014

Analysis of the effects of five factors relevant to in vitro chondrogenesis of human mesenchymal stem cells using factorial design and high throughput mRNA-profiling

artículo científico publicado en 2014

Brief report: importance of SOX8 for in vitro chondrogenic differentiation of human mesenchymal stromal cells

artículo científico publicado en 2014

Cellular source and mechanisms of high transcriptome complexity in the mammalian testis

artículo científico publicado en 2013

Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals

artículo científico publicado en 2009

Combinatorial single-cell CRISPR screens by direct guide RNA capture and targeted sequencing

scientific article published on 30 March 2020

Comparative Epigenomic Analysis of Murine and Human Adipogenesis ⬇️

artículo científico publicado el 1 de octubre de 2010

Comprehensive mutational scanning of a kinase in vivo reveals substrate-dependent fitness landscapes

artículo científico publicado en 2014

Convergent and divergent evolution of genomic imprinting in the marsupial Monodelphis domestica

artículo científico publicado en 2012

DNA sequence and analysis of human chromosome 18

artículo científico publicado en 2005

DNA sequence and analysis of human chromosome 8

artículo científico publicado en 2006

Defining the human C2H2 zinc finger degrome targeted by thalidomide analogs through CRBN

artículo científico publicado en 2018

Direct Identification of Hundreds of Expression-Modulating Variants using a Multiplexed Reporter Assay

artículo científico publicado en 2016

Direct Identification of Hundreds of Expression-Modulating Variants using a Multiplexed Reporter Assay

scientific article published on 01 February 2018

Dissecting neural differentiation regulatory networks through epigenetic footprinting

artículo científico publicado en 2014

Dynamics of lineage commitment revealed by single-cell transcriptomics of differentiating embryonic stem cells

artículo científico publicado en 2017

Early B-cell factor-1 (EBF1) is a key regulator of metabolic and inflammatory signaling pathways in mature adipocytes

artículo científico publicado en 2013

Enhanced methods for unbiased deep sequencing of Lassa and Ebola RNA viruses from clinical and biological samples

artículo científico publicado en 2014

Erratum: Corrigendum: DNA sequence and analysis of human chromosome 18

artículo científico publicado en 2005

FOSL2 promotes leptin gene expression in human and mouse adipocytes

artículo científico publicado en 2012

Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences

artículo científico publicado en 2007

Genome sequence, comparative analysis and haplotype structure of the domestic dog

artículo científico publicado en 2005

Genome-scale DNA methylation mapping of clinical samples at single-nucleotide resolution

artículo científico publicado en 2010

Genome-scale DNA methylation maps of pluripotent and differentiated cells

artículo científico publicado en 2008

Genome-scale high-resolution mapping of activating and repressive nucleotides in regulatory regions

artículo científico publicado en 2016

Genome-wide map of quantified epigenetic changes during in vitro chondrogenic differentiation of primary human mesenchymal stem cells

artículo científico publicado en 2013

Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

artículo científico publicado en 2007

Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains

artículo científico publicado en 2008

High-resolution mapping reveals a conserved, widespread, dynamic mRNA methylation program in yeast meiosis

artículo científico publicado en 2013

Identification of Functional Variants in the FAM13A Chronic Obstructive Pulmonary Disease Genome-Wide Association Study Locus by Massively Parallel Reporter Assays

artículo científico publicado en 2019

Identification of nuclear hormone receptor pathways causing insulin resistance by transcriptional and epigenomic analysis.

artículo científico publicado en 2014

Improving genome annotations using phylogenetic profile anomaly detection

artículo científico publicado en 2004

Initial sequencing and analysis of the human genome

artículo científico publicado en 2001

Integrative Analyses of Human Reprogramming Reveal Dynamic Nature of Induced Pluripotency

artículo científico publicado en 2015

Integrative genomics identifies the corepressor SMRT as a gatekeeper of adipogenesis through the transcription factors C/EBPβ and KAISO.

artículo científico publicado en 2012

Intestinal Enteroendocrine Lineage Cells Possess Homeostatic and Injury-Inducible Stem Cell Activity

artículo científico publicado en 2017

LIN28 Regulates Stem Cell Metabolism and Conversion to Primed Pluripotency

artículo científico publicado en 2016

Large, Diverse Population Cohorts of hiPSCs and Derived Hepatocyte-like Cells Reveal Functional Genetic Variation at Blood Lipid-Associated Loci

artículo científico publicado en 2017

Loss of DNA methyltransferase activity in primed human ES cells triggers increased cell-cell variability and transcriptional repression

artículo científico publicado en 2019

Massively parallel digital transcriptional profiling of single cells

artículo científico publicado en 2017

Massively parallel reporter assays in cultured mammalian cells

artículo científico publicado en 2014

Neural-specific Sox2 input and differential Gli-binding affinity provide context and positional information in Shh-directed neural patterning

artículo científico publicado en 2012

Non-equivalence of Wnt and R-spondin ligands during Lgr5+ intestinal stem-cell self-renewal

artículo científico publicado en 2017

Open source handheld-based EMR for paramedics working in rural areas.

artículo científico publicado en 2002

Organism-Level Analysis of Vaccination Reveals Networks of Protection across Tissues.

artículo científico publicado en 2017

Parallel derivation of isogenic human primed and naive induced pluripotent stem cells

artículo científico publicado en 2018

Perturbation of m6A writers reveals two distinct classes of mRNA methylation at internal and 5' sites

artículo científico publicado en 2014

Phenotypic Characterization of a Comprehensive Set of MAPK1/ERK2 Missense Mutants

artículo científico publicado en 2016

Progenitor identification and SARS-CoV-2 infection in human distal lung organoids

scientific article published on 25 November 2020

Progenitor identification and SARS-CoV-2 infection in long-term human distal lung organoid cultures

scientific article published on 27 July 2020

Prospective functional classification of all possible missense variants in PPARG.

artículo científico publicado en 2016

Registry in a tube: multiplexed pools of retrievable parts for genetic design space exploration

scientific article published on 01 February 2017

Registry in a tube: multiplexed pools of retrievable parts for genetic design space exploration.

artículo científico publicado en 2016

Simultaneous Pathway Activity Inference and Gene Expression Analysis Using RNA Sequencing

artículo científico publicado en 2016

Solving nonlinear polynomial systems in the barycentric Bernstein basis

System-wide genomic and biochemical comparisons of sialic acid biology among primates and rodents: Evidence for two modes of rapid evolution

artículo científico

Systematic Functional Dissection of Common Genetic Variation Affecting Red Blood Cell Traits

artículo científico publicado en 2016

Systematic discovery of regulatory motifs in conserved regions of the human genome, including thousands of CTCF insulator sites

artículo científico publicado en 2007

Systematic dissection and optimization of inducible enhancers in human cells using a massively parallel reporter assay

artículo científico publicado en 2012

Systematic dissection of genomic features determining transcription factor binding and enhancer function

artículo científico publicado en 2017

Systematic dissection of regulatory motifs in 2000 predicted human enhancers using a massively parallel reporter assay

artículo científico publicado en 2013

The DAILY (Daily Automated Intensive Log for Youth) trial: a wireless, portable system to improve adherence and glycemic control in youth with diabetes

artículo científico publicado en 2004

The NIH Roadmap Epigenomics Mapping Consortium

artículo científico publicado en 2010

The case for selection at CCR5-Delta32

artículo científico publicado en 2005

The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

artículo científico publicado en 2014

The regulatory landscape of osteogenic differentiation

artículo científico publicado en 2014

What makes us human?

artículo científico publicado en 2004

ZBED6 modulates the transcription of myogenic genes in mouse myoblast cells

artículo científico publicado en 2014

ZBED6, a novel transcription factor derived from a domesticated DNA transposon regulates IGF2 expression and muscle growth

artículo científico publicado en 2009

microRNA-140 targets RALA and regulates chondrogenic differentiation of human mesenchymal stem cells by translational enhancement of SOX9 and ACAN.

artículo científico publicado en 2013

Lista de obras de

A bivalent chromatin structure marks key developmental genes in embryonic stem cells

A distant trophoblast-specific enhancer controls HLA-G expression at the maternal-fetal interface

A human-specific gene in microglia.

A second fatty acid amide hydrolase with variable distribution among placental mammals

A unique regulatory phase of DNA methylation in the early mammalian embryo ⬇️

Aligning Single-Cell Developmental and Reprogramming Trajectories Identifies Molecular Determinants of Myogenic Reprogramming Outcome

Altered chromatin occupancy of master regulators underlies evolutionary divergence in the transcriptional landscape of erythroid differentiation

Analysis of the effects of five factors relevant to in vitro chondrogenesis of human mesenchymal stem cells using factorial design and high throughput mRNA-profiling

Brief report: importance of SOX8 for in vitro chondrogenic differentiation of human mesenchymal stromal cells

Cellular source and mechanisms of high transcriptome complexity in the mammalian testis

Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals

Combinatorial single-cell CRISPR screens by direct guide RNA capture and targeted sequencing

Comparative Epigenomic Analysis of Murine and Human Adipogenesis ⬇️

Comprehensive mutational scanning of a kinase in vivo reveals substrate-dependent fitness landscapes

Convergent and divergent evolution of genomic imprinting in the marsupial Monodelphis domestica

DNA sequence and analysis of human chromosome 18

DNA sequence and analysis of human chromosome 8

Defining the human C2H2 zinc finger degrome targeted by thalidomide analogs through CRBN

Direct Identification of Hundreds of Expression-Modulating Variants using a Multiplexed Reporter Assay

Direct Identification of Hundreds of Expression-Modulating Variants using a Multiplexed Reporter Assay

Dissecting neural differentiation regulatory networks through epigenetic footprinting

Dynamics of lineage commitment revealed by single-cell transcriptomics of differentiating embryonic stem cells

Early B-cell factor-1 (EBF1) is a key regulator of metabolic and inflammatory signaling pathways in mature adipocytes

Enhanced methods for unbiased deep sequencing of Lassa and Ebola RNA viruses from clinical and biological samples

Erratum: Corrigendum: DNA sequence and analysis of human chromosome 18

FOSL2 promotes leptin gene expression in human and mouse adipocytes

Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences

Genome sequence, comparative analysis and haplotype structure of the domestic dog

Genome-scale DNA methylation mapping of clinical samples at single-nucleotide resolution

Genome-scale DNA methylation maps of pluripotent and differentiated cells

Genome-scale high-resolution mapping of activating and repressive nucleotides in regulatory regions

Genome-wide map of quantified epigenetic changes during in vitro chondrogenic differentiation of primary human mesenchymal stem cells

Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains

High-resolution mapping reveals a conserved, widespread, dynamic mRNA methylation program in yeast meiosis

Identification of Functional Variants in the FAM13A Chronic Obstructive Pulmonary Disease Genome-Wide Association Study Locus by Massively Parallel Reporter Assays

Identification of nuclear hormone receptor pathways causing insulin resistance by transcriptional and epigenomic analysis.

Improving genome annotations using phylogenetic profile anomaly detection

Initial sequencing and analysis of the human genome

Integrative Analyses of Human Reprogramming Reveal Dynamic Nature of Induced Pluripotency

Integrative genomics identifies the corepressor SMRT as a gatekeeper of adipogenesis through the transcription factors C/EBPβ and KAISO.

Intestinal Enteroendocrine Lineage Cells Possess Homeostatic and Injury-Inducible Stem Cell Activity

LIN28 Regulates Stem Cell Metabolism and Conversion to Primed Pluripotency

Large, Diverse Population Cohorts of hiPSCs and Derived Hepatocyte-like Cells Reveal Functional Genetic Variation at Blood Lipid-Associated Loci

Loss of DNA methyltransferase activity in primed human ES cells triggers increased cell-cell variability and transcriptional repression

Massively parallel digital transcriptional profiling of single cells

Massively parallel reporter assays in cultured mammalian cells

Neural-specific Sox2 input and differential Gli-binding affinity provide context and positional information in Shh-directed neural patterning

Non-equivalence of Wnt and R-spondin ligands during Lgr5+ intestinal stem-cell self-renewal

Open source handheld-based EMR for paramedics working in rural areas.

Organism-Level Analysis of Vaccination Reveals Networks of Protection across Tissues.

Parallel derivation of isogenic human primed and naive induced pluripotent stem cells

Perturbation of m6A writers reveals two distinct classes of mRNA methylation at internal and 5' sites

Phenotypic Characterization of a Comprehensive Set of MAPK1/ERK2 Missense Mutants

Progenitor identification and SARS-CoV-2 infection in human distal lung organoids

Progenitor identification and SARS-CoV-2 infection in long-term human distal lung organoid cultures

Prospective functional classification of all possible missense variants in PPARG.

Registry in a tube: multiplexed pools of retrievable parts for genetic design space exploration

Registry in a tube: multiplexed pools of retrievable parts for genetic design space exploration.

Simultaneous Pathway Activity Inference and Gene Expression Analysis Using RNA Sequencing

Solving nonlinear polynomial systems in the barycentric Bernstein basis

System-wide genomic and biochemical comparisons of sialic acid biology among primates and rodents: Evidence for two modes of rapid evolution

Systematic Functional Dissection of Common Genetic Variation Affecting Red Blood Cell Traits

Systematic discovery of regulatory motifs in conserved regions of the human genome, including thousands of CTCF insulator sites

Systematic dissection and optimization of inducible enhancers in human cells using a massively parallel reporter assay

Systematic dissection of genomic features determining transcription factor binding and enhancer function

Systematic dissection of regulatory motifs in 2000 predicted human enhancers using a massively parallel reporter assay

The DAILY (Daily Automated Intensive Log for Youth) trial: a wireless, portable system to improve adherence and glycemic control in youth with diabetes

The NIH Roadmap Epigenomics Mapping Consortium

The case for selection at CCR5-Delta32

The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

The regulatory landscape of osteogenic differentiation

What makes us human?

ZBED6 modulates the transcription of myogenic genes in mouse myoblast cells

ZBED6, a novel transcription factor derived from a domesticated DNA transposon regulates IGF2 expression and muscle growth

microRNA-140 targets RALA and regulates chondrogenic differentiation of human mesenchymal stem cells by translational enhancement of SOX9 and ACAN.