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A New Understanding of the Role of IL-1 in Age-Related Intervertebral Disc Degeneration in a Murine Model

scientific article published on 29 May 2019

An organ culture system to model early degenerative changes of the intervertebral disc II: profiling global gene expression changes

artículo científico publicado en 2013

Comparison of inbred mouse strains shows diverse phenotypic outcomes of intervertebral disc aging

scientific article published on 22 April 2020

Differential Effect of Long-Term Systemic Exposure of TNFα on Health of the Annulus Fibrosus and Nucleus Pulposus of the Intervertebral Disc

scientific article published on 06 January 2020

Differential gene expression in anterior and posterior annulus fibrosus

artículo científico publicado en 2014

Expression and Relationship of Proinflammatory Chemokine RANTES/CCL5 and Cytokine IL-1β in Painful Human Intervertebral Discs

artículo científico publicado el 15 de mayo de 2013

Hypoxic regulation of mitochondrial metabolism and mitophagy in nucleus pulposus cells is dependent on HIF-1α -BNIP3 axis

artículo científico publicado en 2020

Lactate Efflux From Intervertebral Disc Cells Is Required for Maintenance of Spine Health

scientific article published on 12 December 2019

Nucleus pulposus primary cilia alter their length in response to changes in extracellular osmolarity but do not control TonEBP-mediated osmoregulation

artículo científico publicado en 2019

Substance P Receptor Antagonist Suppresses Inflammatory Cytokine Expression in Human Disc Cells

artículo científico publicado en 2015

Substance P Stimulates Production of Inflammatory Cytokines in Human Disc Cells

artículo científico publicado el 1 de octubre de 2013

Transgenic mice overexpressing human TNF-α experience early onset spontaneous intervertebral disc herniation in the absence of overt degeneration

artículo científico publicado en 2018

Understanding embryonic development for cell-based therapies of intervertebral disc degeneration: Towards an effort to treat disc degeneration subphenotypes

scientific article published on 21 June 2020