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3,4-Dihydroxyphenylalanine Peptides as Nonperturbative Quantum Dot Sensors of Aminopeptidase

artículo científico publicado en 2016

5-Imino-1,2-4-thiadiazoles and quinazolines derivatives as glycogen synthase kinase 3β (GSK-3β) and phosphodiesterase 7 (PDE7) inhibitors: determination of blood-brain barrier penetration and binding to human serum albumin.

artículo científico publicado en 2012

5-imino-1,2,4-thiadiazoles: first small molecules as substrate competitive inhibitors of glycogen synthase kinase 3.

artículo científico publicado en 2012

Crosstalk between phosphodiesterase 7 and glycogen synthase kinase-3: two relevant therapeutic targets for neurological disorders

artículo científico publicado en 2014

Delivery and tracking of quantum dot peptide bioconjugates in an intact developing avian brain

artículo científico publicado en 2015

Drugs in clinical development for the treatment of amyotrophic lateral sclerosis

artículo científico publicado en 2017

Dual inhibitor of PDE7 and GSK-3-VP1.15 acts as antipsychotic and cognitive enhancer in C57BL/6J mice

artículo científico publicado en 2012

Efficient Assembly of Quantum Dots with Homogenous Glycans Derived from Natural N-Linked Glycoproteins

scientific article published on 20 August 2018

Exploring the binding sites of glycogen synthase kinase 3. Identification and characterization of allosteric modulation cavities.

artículo científico publicado en 2011

Glycogen synthase kinase 3 inhibition promotes adult hippocampal neurogenesis in vitro and in vivo.

artículo científico publicado en 2012

Identification in silico and experimental validation of novel phosphodiesterase 7 inhibitors with efficacy in experimental autoimmune encephalomyelitis mice

artículo científico publicado en 2012

Modulation of GSK-3 provides cellular and functional neuroprotection in the rd10 mouse model of retinitis pigmentosa.

artículo científico publicado en 2018

PDE 7 inhibitors: new potential drugs for the therapy of spinal cord injury

artículo científico publicado en 2011

Promoting in vivo remyelination with small molecules: a neuroreparative pharmacological treatment for Multiple Sclerosis.

artículo científico publicado en 2017

Purple-, Blue-, and Green-Emitting Multishell Alloyed Quantum Dots: Synthesis, Characterization, and Application for Ratiometric Extracellular pH Sensing

Small GSK-3 Inhibitor Shows Efficacy in a Motor Neuron Disease Murine Model Modulating Autophagy

artículo científico publicado en 2016

Small molecules targeting glycogen synthase kinase 3 as potential drug candidates for the treatment of retinitis pigmentosa.

artículo científico publicado en 2017

Subtly Modulating Glycogen Synthase Kinase 3 β: Allosteric Inhibitor Development and Their Potential for the Treatment of Chronic Diseases

artículo científico

TDP-43: A Key Therapeutic Target beyond Amyotrophic Lateral Sclerosis

scientific article published on 04 March 2019

The GSK-3-inhibitor VP2.51 produces antidepressant effects associated with adult hippocampal neurogenesis

artículo científico publicado en 2016

The Potential Role of Glycogen Synthase Kinase 3 Inhibitors as Amyotrophic Lateral Sclerosis Pharmacological Therapy

artículo científico publicado el 1 de enero de 2011