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"Score the Core" Web-based pathologist training tool improves the accuracy of breast cancer IHC4 scoring

artículo científico publicado en 2015

'One medicine---one pathology': are veterinary and human pathology prepared?

artículo científico publicado en 2007

A Review of Current Standards and the Evolution of Histopathology Nomenclature for Laboratory Animals

article

A critical role for p27kip1 gene dosage in a mouse model of prostate carcinogenesis.

artículo científico publicado en 2004

ANCCA/ATAD2 Overexpression Identifies Breast Cancer Patients with Poor Prognosis, Acting to Drive Proliferation and Survival of Triple-Negative Cells through Control of B-Myb and EZH2 ⬇️

artículo científico publicado el 23 de septiembre de 2010

Abnormal Mammary Development in 129:STAT1-Null Mice is Stroma-Dependent

artículo científico publicado en 2015

Acceleration of mouse mammary tumor virus-induced murine mammary tumorigenesis by a p53 172H transgene: influence of FVB background on tumor latency and identification of novel sites of proviral insertion

artículo científico publicado en 2002

Accumulation, internalization and therapeutic efficacy of neuropilin-1-targeted liposomes

artículo científico publicado en 2014

Activation of Akt-1 (PKB-alpha) can accelerate ErbB-2-mediated mammary tumorigenesis but suppresses tumor invasion

artículo científico publicado en 2004

Activation of beta -catenin signaling in differentiated mammary secretory cells induces transdifferentiation into epidermis and squamous metaplasias.

artículo científico publicado en 2002

Activation of beta-catenin in prostate epithelium induces hyperplasias and squamous transdifferentiation

scientific journal article

Activation of different Wnt/beta-catenin signaling components in mammary epithelium induces transdifferentiation and the formation of pilar tumors

artículo científico publicado en 2002

Adiponectin deficiency limits tumor vascularization in the MMTV-PyV-mT mouse model of mammary cancer

artículo científico publicado en 2009

Advancing translational research

scientific article published on 01 March 2011

Aging Mouse Models Reveal Complex Tumor-Microenvironment Interactions in Cancer Progression

artículo científico publicado en 2018

An integrin binding-defective mutant of insulin-like growth factor-1 (R36E/R37E IGF1) acts as a dominant-negative antagonist of the IGF1 receptor (IGF1R) and suppresses tumorigenesis but still binds to IGF1R.

artículo científico publicado en 2013

An open environment CT-US fusion for tissue segmentation during interventional guidance

artículo científico publicado en 2011

Analysis of mouse model pathology: a primer for studying the anatomic pathology of genetically engineered mice

artículo científico publicado en 2014

Angiogenic acceleration of Neu induced mammary tumor progression and metastasis

artículo científico publicado en 2004

Animal Models of Human Prostate Cancer: The Consensus Report of the New York Meeting of the Mouse Models of Human Cancers Consortium Prostate Pathology Committee ⬇️

artículo científico publicado el 22 de abril de 2013

B-Raf activation cooperates with PTEN loss to drive c-Myc expression in advanced prostate cancer

artículo científico publicado en 2012

Bethesda proposals for classification of nonlymphoid hematopoietic neoplasms in mice

scientific article published on 01 July 2002

Classification of proliferative pulmonary lesions of the mouse: recommendations of the mouse models of human cancers consortium

artículo científico publicado en 2004

Contributions of mouse biology to breast cancer research

artículo científico publicado en 2002

Cooperativity of Nkx3.1 and Pten loss of function in a mouse model of prostate carcinogenesis.

artículo científico publicado en 2002

Copper-doxorubicin as a nanoparticle cargo retains efficacy with minimal toxicity

artículo científico publicado en 2010

CrkII transgene induces atypical mammary gland development and tumorigenesis

artículo científico publicado en 2009

Decoding Intratumoral Heterogeneity of Breast Cancer by Multiparametric In Vivo Imaging: A Translational Study

artículo científico publicado en 2016

Diet-induced metabolic change induces estrogen-independent allometric mammary growth

artículo científico publicado en 2012

Differential sensitivity of mouse epithelial tissues to the polyomavirus middle T oncogene

artículo científico publicado en 2006

Dissociation of epithelial and neuroendocrine carcinoma lineages in the transgenic adenocarcinoma of mouse prostate model of prostate cancer

artículo científico publicado en 2007

Distinct ErbB-2 coupled signaling pathways promote mammary tumors with unique pathologic and transcriptional profiles

artículo científico publicado en 2007

Do-it-yourself (DIY) pathology

artículo científico publicado en 2008

Dual targeting of the Akt/mTOR signaling pathway inhibits castration-resistant prostate cancer in a genetically engineered mouse model.

artículo científico publicado en 2012

E mu-BRD2 transgenic mice develop B-cell lymphoma and leukemia.

artículo científico publicado en 2003

EMT tumorigenesis in the mouse mammary gland

artículo científico publicado en 2007

ETV4 promotes metastasis in response to activation of PI3-kinase and Ras signaling in a mouse model of advanced prostate cancer.

artículo científico publicado en 2013

Early vascular deficits are correlated with delayed mammary tumorigenesis in the MMTV-PyMT transgenic mouse following genetic ablation of the NG2 proteoglycan ⬇️

artículo científico publicado el 24 de abril de 2012

Effect of c-neu/ ErbB2 expression levels on estrogen receptor alpha-dependent proliferation in mammary epithelial cells: implications for breast cancer biology

artículo científico publicado en 2006

Effects of FVB/NJ and C57Bl/6J strain backgrounds on mammary tumor phenotype in inducible nitric oxide synthase deficient mice

artículo científico publicado en 2007

Enhanced in vivo bioluminescence imaging using liposomal luciferin delivery system

artículo científico publicado en 2009

Environmental Exposures during Puberty: Window of Breast Cancer Risk and Epigenetic Damage

artículo científico publicado en 2020

Epidermal growth factor receptor-dependent activation of Gab1 is involved in ErbB-2-mediated mammary tumor progression

artículo científico publicado en 2003

Epithelial-mesenchymal transition in mouse mammary tumorigenesis

artículo científico publicado en 2009

Ets2-dependent stromal regulation of mouse mammary tumors

artículo científico publicado en 2003

Evidence for Phenotypic Plasticity in Aggressive Triple-Negative Breast Cancer: Human Biology Is Recapitulated by a Novel Model System ⬇️

artículo científico publicado el 25 de septiembre de 2012

Fibroblast growth factor receptor signaling dramatically accelerates tumorigenesis and enhances oncoprotein translation in the mouse mammary tumor virus-Wnt-1 mouse model of breast cancer

artículo científico publicado en 2010

From whence will they come? - A perspective on the acute shortage of pathologists in biomedical research

artículo científico publicado en 2007

Gene expression profiling of neu-induced mammary tumors from transgenic mice reveals genetic and morphological similarities to ErbB2-expressing human breast cancers

scientific article published on 01 August 2003

Genetic heterogeneity of Myc-induced mammary tumors reflecting diverse phenotypes including metastatic potential

scholarly article

HER2/neu-induced mammary tumorigenesis and angiogenesis are reduced in cyclooxygenase-2 knockout mice.

artículo científico publicado en 2005

Heterogeneity of mammary lesions represent molecular differences

artículo científico publicado en 2006

Histopathology as a predictive biomarker: strengths and limitations

artículo científico publicado en 2006

Id-1 is not expressed in the luminal epithelial cells of mammary glands

artículo científico publicado en 2003

In vivo positron-emission tomography imaging of progression and transformation in a mouse model of mammary neoplasia

scholarly article

Insights from transgenic mouse models of ERBB2-induced breast cancer

artículo científico publicado en 2007

Introduction of Zinc-salt Fixation for Effective Detection of Immune Cell-related Markers by Immunohistochemistry

artículo científico publicado en 2015

Kinase-inactive glycogen synthase kinase 3beta promotes Wnt signaling and mammary tumorigenesis.

artículo científico publicado en 2005

Limited mouse necropsy

artículo científico publicado en 2014

Lineage analysis of basal epithelial cells reveals their unexpected plasticity and supports a cell-of-origin model for prostate cancer heterogeneity

artículo científico publicado en 2013

Longitudinal investigation of permeability and distribution of macromolecules in mouse malignant transformation using PET.

artículo científico publicado en 2010

Loss of Nrdp1 enhances ErbB2/ErbB3-dependent breast tumor cell growth

artículo científico publicado en 2006

Magnetic resonance imaging assessment of effective ablated volume following high intensity focused ultrasound

artículo científico publicado en 2015

Male mice not alone in research

artículo científico publicado en 2010

Mammary carcinoma behavior is programmed in the precancer stem cell

artículo científico publicado en 2008

Mammary epithelial-specific disruption of the focal adhesion kinase blocks mammary tumor progression

artículo científico publicado en 2007

Mammary tumor latency is increased in mice lacking the inducible nitric oxide synthase

artículo científico publicado en 2003

Mammary tumorigenesis following transgenic expression of a dominant negative CHK2 mutant

artículo científico publicado en 2006

Manual hematoxylin and eosin staining of mouse tissue sections

artículo científico publicado en 2014

Manual immunohistochemistry staining of mouse tissues using the avidin-biotin complex (ABC) technique.

artículo científico publicado en 2014

Met induces mammary tumors with diverse histologies and is associated with poor outcome and human basal breast cancer

scholarly article

Met synergizes with p53 loss to induce mammary tumors that possess features of claudin-low breast cancer

artículo científico publicado en 2013

Methods of Immunohistochemistry and Immunofluorescence: Converting Invisible to Visible.

artículo científico publicado en 2016

Mice expressing SV40 T antigen directed by the intestinal trefoil factor promoter develop tumors resembling human small cell carcinoma of the colon

artículo científico publicado en 2004

Molecular analysis of metastasis in a polyomavirus middle T mouse model: the role of osteopontin

artículo científico publicado en 2004

Molecular characterization of the transition to malignancy in a genetically engineered mouse-based model of ductal carcinoma in situ.

artículo científico publicado en 2004

Mouse mammary tumor virus c-rel transgenic mice develop mammary tumors

artículo científico publicado en 2003

Mouse models of human cancers (Part 2).

artículo científico publicado en 2004

Mouse models of human cancers (part 3).

artículo científico publicado en 2004

Mouse tissue fixation

artículo científico publicado en 2014

Multipotent luminal mammary cancer stem cells model tumor heterogeneity

artículo científico publicado en 2015

Nkx3.1 mutant mice recapitulate early stages of prostate carcinogenesis

artículo científico publicado en 2002

Nkx3.1; Pten mutant mice develop invasive prostate adenocarcinoma and lymph node metastases

artículo científico publicado en 2003

Oncogenic signaling pathways activated in DMBA-induced mouse mammary tumors.

artículo científico publicado en 2005

Over 60% of NIH extramural funding involves animal-related research

scientific article published on 01 November 2007

Overexpression of progesterone receptor A isoform in mice leads to endometrial hyperproliferation, hyperplasia and atypia

artículo científico publicado en 2009

PTEN deficiency in a luminal ErbB-2 mouse model results in dramatic acceleration of mammary tumorigenesis and metastasis

scientific article published on 12 May 2009

PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms

artículo científico publicado en 2003

Pathobiology of the 129:Stat1 -/- mouse model of human age-related ER-positive breast cancer with an immune infiltrate-excluded phenotype

artículo científico publicado en 2017

Pathway pathology: histological differences between ErbB/Ras and Wnt pathway transgenic mammary tumors

artículo científico publicado en 2002

Persistent mammary hyperplasia in FVB/N mice

artículo científico publicado el 1 de agosto de 2003

Phosphatase and tensin homologue deleted on chromosome 10 deficiency accelerates tumor induction in a mouse model of ErbB-2 mammary tumorigenesis

artículo científico publicado en 2008

Polyomavirus middle T-induced mammary intraepithelial neoplasia outgrowths: single origin, divergent evolution, and multiple outcomes

artículo científico publicado en 2004

Precancer in mice: animal models used to understand, prevent, and treat human precancers

artículo científico publicado en 2006

Precancer: sequentially acquired or predetermined?

artículo científico publicado en 2009

Preclinical imaging of mammary intraepithelial neoplasia with positron emission tomography

artículo científico publicado en 2006

Prostate pathology of genetically engineered mice: definitions and classification. The consensus report from the Bar Harbor meeting of the Mouse Models of Human Cancer Consortium Prostate Pathology Committee.

artículo científico publicado en 2004

Prostatic intraepithelial neoplasia in genetically engineered mice

artículo científico publicado en 2002

Quantitation of fixative-induced morphologic and antigenic variation in mouse and human breast cancers.

scientific article published on 11 February 2013

Rapamycin inhibits growth of premalignant and malignant mammary lesions in a mouse model of ductal carcinoma in situ.

artículo científico publicado en 2006

Regulation of glutamine carrier proteins by RNF5 determines breast cancer response to ER stress-inducing chemotherapies

artículo científico publicado en 2015

Rheb1-Independent Activation of mTORC1 in Mammary Tumors Occurs through Activating Mutations in mTOR

scientific article published on 01 April 2020

STAT1-deficient mice spontaneously develop estrogen receptor α-positive luminal mammary carcinomas

artículo científico publicado en 2012

Selective estrogen receptor modulators inhibit growth and progression of premalignant lesions in a mouse model of ductal carcinoma in situ

artículo científico publicado en 2005

ShcA signalling is essential for tumour progression in mouse models of human breast cancer

scientific journal article

Siah2-dependent concerted activity of HIF and FoxA2 regulates formation of neuroendocrine phenotype and neuroendocrine prostate tumors

artículo científico publicado en 2010

Simultaneous haploinsufficiency of Pten and Trp53 tumor suppressor genes accelerates tumorigenesis in a mouse model of prostate cancer.

artículo científico publicado en 2008

Single unpurified breast tumor-initiating cells from multiple mouse models efficiently elicit tumors in immune-competent hosts

artículo científico publicado en 2013

Somatic mutation of p53 leads to estrogen receptor alpha-positive and -negative mouse mammary tumors with high frequency of metastasis

artículo científico publicado en 2004

Spontaneous pituitary abnormalities and mammary hyperplasia in FVB/NCr mice: implications for mouse modeling.

artículo científico publicado en 2003

Structured reporting in anatomic pathology for coclinical trials: the caELMIR model

artículo científico publicado en 2014

Suppression of the negative regulator LRIG1 contributes to ErbB2 overexpression in breast cancer

scientific article published on October 2008

Syngeneic mouse mammary carcinoma cell lines: two closely related cell lines with divergent metastatic behavior

artículo científico publicado en 2005

T-cadherin supports angiogenesis and adiponectin association with the vasculature in a mouse mammary tumor model

artículo científico publicado en 2008

The E2F transcription factors regulate tumor development and metastasis in a mouse model of metastatic breast cancer

artículo científico publicado en 2014

The Trp53 delta proline (Trp53ΔP) mouse exhibits increased genome instability and susceptibility to radiation-induced, but not spontaneous, tumor development

artículo científico publicado en 2015

The WNT10B Network Is Associated with Survival and Metastases in Chemoresistant Triple-Negative Breast Cancer

artículo científico publicado en 2018

The genomic revolution and endocrine pathology

artículo científico publicado en 2008

The membrane mucin MUC4 is elevated in breast tumor lymph node metastases relative to matched primary tumors and confers aggressive properties to breast cancer cells

artículo científico publicado en 2009

The use of mouse models of breast cancer and quantitative image analysis to evaluate hormone receptor antigenicity after microwave-assisted formalin fixation

artículo científico publicado en 2014

Three interrelated themes in current breast cancer research: gene addiction, phenotypic plasticity, and cancer stem cells

artículo científico publicado en 2011

Transforming growth factor beta signaling impairs Neu-induced mammary tumorigenesis while promoting pulmonary metastasis

artículo científico publicado en 2003

Ultrasound Increases Nanoparticle Delivery by Reducing Intratumoral Pressure and Increasing Transport in Epithelial and Epithelial–Mesenchymal Transition Tumors ⬇️

artículo científico publicado el 26 de enero de 2012

Validation of transgenic mammary cancer models: goals of the NCI Mouse Models of Human Cancer Consortium and the mammary cancer CD-ROM

artículo científico publicado en 2002

Validation: the new challenge for pathology

artículo científico publicado en 2004

pRb inactivation in mammary cells reveals common mechanisms for tumor initiation and progression in divergent epithelia

artículo científico publicado en 2004

β-Catenin haploinsufficiency promotes mammary tumorigenesis in an ErbB2-positive basal breast cancer model

artículo científico publicado en 2017

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