Lista de obras -

A Multicenter, Open-Label Phase II Clinical Trial of Combined MEK plus EGFR Inhibition for Chemotherapy-Refractory Advanced Pancreatic Adenocarcinoma

artículo científico publicado en 2015

A central role for RAF→MEK→ERK signaling in the genesis of pancreatic ductal adenocarcinoma.

artículo científico publicado en 2012

A colorectal cancer classification system that associates cellular phenotype and responses to therapy

artículo científico publicado en 2013

A robust prognostic signature for hormone-positive node-negative breast cancer

artículo científico publicado en 2013

APOBEC mutation drives early-onset squamous cell carcinomas in recessive dystrophic epidermolysis bullosa

artículo científico publicado en 2018

Abstract 2985: Predicting the impact of mutations in cancer using an integrated pathway approach

Abstract 5087: UCSC Cancer Genomics Browser 2.0

Activation of MET via diverse exon 14 splicing alterations occurs in multiple tumor types and confers clinical sensitivity to MET inhibitors

artículo científico publicado en 2015

Advances in the Genetics and Biology of Pancreatic Cancer

artículo científico publicado en 2017

Alliance for clinical trials in oncology (ALLIANCE) trial A021501: preoperative extended chemotherapy vs. chemotherapy plus hypofractionated radiation therapy for borderline resectable adenocarcinoma of the head of the pancreas

artículo científico publicado en 2017

An improved CTC isolation scheme for pairing with downstream genomics: Demonstrating clinical utility in metastatic prostate, lung and pancreatic cancer

artículo científico publicado en 2016

Analytical and Clinical Validation of a Digital Sequencing Panel for Quantitative, Highly Accurate Evaluation of Cell-Free Circulating Tumor DNA

artículo científico publicado en 2015

Atorvastatin prevents RhoC isoprenylation, invasion, and metastasis in human melanoma cells ⬇️

artículo científico publicado el 1 de octubre de 2003

Bioluminescent imaging of melanoma in live mice

artículo científico publicado en 2005

Blinded by the Light: Molecular Imaging in Pancreatic Adenocarcinoma ⬇️

artículo científico publicado el 24 de noviembre de 2010

Blockade of leukemia inhibitory factor as a therapeutic approach to KRAS driven pancreatic cancer

scientific article published on 11 July 2019

Blockchain-Authenticated Sharing of Genomic and Clinical Outcomes Data of Patients With Cancer: A Prospective Cohort Study

artículo científico publicado en 2020

Brg1 promotes both tumor-suppressive and oncogenic activities at distinct stages of pancreatic cancer formation

artículo científico publicado en 2015

Bringing Pancreas Cancer into the Lab

artículo científico publicado en 2018

Cell of origin and mutation pattern define three clinically distinct classes of sebaceous carcinoma.

artículo científico publicado en 2018

Cell-Free DNA Next-Generation Sequencing in Pancreatobiliary Carcinomas.

artículo científico publicado en 2015

Circulating tumor cells in hepatocellular carcinoma: a pilot study of detection, enumeration, and next-generation sequencing in cases and controls

artículo científico publicado en 2015

Clinical Sequencing Contributes to a BRCA-Associated Cancer Rediagnosis That Guides an Effective Therapeutic Course

artículo científico publicado en 2015

Co-occurring Alterations in the RAS-MAPK Pathway Limit Response to MET Inhibitor Treatment in MET Exon 14 Skipping Mutation-Positive Lung Cancer

scientific article published on 23 September 2019

Correction: Decoupling of the PI3K Pathway via Mutation Necessitates Combinatorial Treatment in HER2+ Breast Cancer

artículo científico publicado en 2017

Decoupling of the PI3K Pathway via Mutation Necessitates Combinatorial Treatment in HER2+ Breast Cancer

artículo científico publicado en 2015

Distinct patterns of somatic genome alterations in lung adenocarcinomas and squamous cell carcinomas

artículo científico publicado en 2016

Distinctions with a Difference: RNA Subtyping and Clinical Outcome In Pancreatic Cancer

scientific article published on 13 July 2020

Early Response Assessment in Pancreatic Ductal Adenocarcinoma Through Integrated PET/MRI

artículo científico publicado en 2018

Election 2016: Voting on Variants.

artículo científico publicado en 2016

Erratum to: Modeling precision treatment of breast cancer

artículo científico publicado en 2015

Estimation of Fractional Extracellular Space at CT for Predicting Chemotherapy Response and Survival in Pancreatic Ductal Adenocarcinoma

scientific article published on 01 July 2020

Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression

artículo científico publicado en 2016

Histology, anatomy, or geography? Exome sequencing begins to delineate somatic mutational differences in esophageal cancer.

artículo científico publicado en 2012

Hybrid Capture-Based Tumor Sequencing and Copy Number Analysis to Confirm Origin of Metachronous Metastases in BRCA1-Mutant Cholangiocarcinoma Harboring a Novel YWHAZ-BRAF Fusion.

artículo científico publicado en 2018

Isoprenylation is necessary for the full invasive potential of RhoA overexpression in human melanoma cells

artículo científico publicado en 2002

Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma

artículo científico publicado en 2011

MET Exon 14 Mutation Encodes an Actionable Therapeutic Target in Lung Adenocarcinoma

artículo científico publicado en 2017

Mapping the molecular determinants of BRAF oncogene dependence in human lung cancer.

artículo científico publicado en 2014

Modeling precision treatment of breast cancer

artículo científico publicado en 2013

Molecular Insights in Transmission of Cancer From an Organ Donor to Four Transplant Recipients

artículo científico publicado en 2020

Molecular subtypes of pancreatic cancer

artículo científico publicado en 2019

Multi-faceted epigenetic dysregulation of gene expression promotes esophageal squamous cell carcinoma

artículo científico publicado en 2020

Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin

artículo científico publicado en 2014

Mutationally activated PIK3CA(H1047R) cooperates with BRAF(V600E) to promote lung cancer progression.

artículo científico publicado en 2013

PARADIGM-SHIFT predicts the function of mutations in multiple cancers using pathway impact analysis

artículo científico publicado en 2012

Pancreatic Cancer Genomics 2.0: Profiling Metastases

artículo científico publicado en 2017

Pancreatic Cancer: Progress and Challenges in a Rapidly Moving Field.

artículo científico publicado en 2017

Pancreatic ductal adenocarcinoma progression is restrained by stromal matrix

artículo científico publicado en 2020

Phylogenetic analyses of melanoma reveal complex patterns of metastatic dissemination.

artículo científico publicado en 2015

Preoperative Modified FOLFIRINOX Treatment Followed by Capecitabine-Based Chemoradiation for Borderline Resectable Pancreatic Cancer: Alliance for Clinical Trials in Oncology Trial A021101.

artículo científico publicado en 2016

RADIA: RNA and DNA integrated analysis for somatic mutation detection

artículo científico publicado en 2014

RAS-MAPK dependence underlies a rational polytherapy strategy in EML4-ALK-positive lung cancer.

artículo científico publicado en 2015

RB and Prognosis in Resected Lung Adenocarcinoma

artículo científico publicado en 2015

Ras-GTP dimers activate the Mitogen-Activated Protein Kinase (MAPK) pathway

artículo científico publicado en 2015

Re: "Clinical Sequencing Contributes to a BRCA-Associated Cancer Rediagnosis That Guides an Effective Therapeutic Course".

artículo científico publicado en 2016

Referral frequency, attrition rate, and outcomes of germline testing in patients with pancreatic adenocarcinoma

artículo científico publicado en 2019

Single-molecule superresolution imaging allows quantitative analysis of RAF multimer formation and signaling

scientific article published on 24 October 2013

Stromal Content Is Correlated With Tissue Site, Contrast Retention, and Survival in Pancreatic Adenocarcinoma

artículo científico publicado en 2018

Stromal cues regulate the pancreatic cancer epigenome and metabolome

artículo científico publicado en 2017

Subtype and pathway specific responses to anticancer compounds in breast cancer

artículo científico publicado en 2011

Subtype-specific MEK-PI3 kinase feedback as a therapeutic target in pancreatic adenocarcinoma

artículo científico publicado en 2013

Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy

artículo científico publicado en 2011

Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring

artículo científico publicado en 2019

Temporal dissection of tumorigenesis in primary cancers

artículo científico publicado en 2011

The Authors Respond

The Cancer Genome Atlas Pan-Cancer analysis project

artículo científico publicado en 2013

The Hippo effector YAP promotes resistance to RAF- and MEK-targeted cancer therapies

artículo científico publicado en 2015

The Role of MR Imaging in Pancreatic Cancer

artículo científico publicado en 2018

Theranostic targeting of CUB domain containing protein 1 (CDCP1) in pancreatic cancer

scientific article published on 27 April 2020

Timing chromosomal abnormalities using mutation data.

artículo científico publicado en 2011

Transcription restores DNA repair to heterochromatin, determining regional mutation rates in cancer genomes.

artículo científico publicado en 2014

Treatment of metastatic melanoma with an orally available inhibitor of the Ras-Raf-MAPK cascade ⬇️

artículo científico publicado el 15 de septiembre de 2003

Ultrasensitive plasma ctDNA KRAS assay for detection, prognosis, and assessment of therapeutic response in patients with unresectable pancreatic ductal adenocarcinoma

artículo científico publicado en 2017

Vitamin D receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy

artículo científico publicado en 2014

What are we learning from the cancer genome?

artículo científico publicado en 2012

Lista de obras de

A Multicenter, Open-Label Phase II Clinical Trial of Combined MEK plus EGFR Inhibition for Chemotherapy-Refractory Advanced Pancreatic Adenocarcinoma

A central role for RAF→MEK→ERK signaling in the genesis of pancreatic ductal adenocarcinoma.

A colorectal cancer classification system that associates cellular phenotype and responses to therapy

A robust prognostic signature for hormone-positive node-negative breast cancer

APOBEC mutation drives early-onset squamous cell carcinomas in recessive dystrophic epidermolysis bullosa

Abstract 2985: Predicting the impact of mutations in cancer using an integrated pathway approach

Abstract 5087: UCSC Cancer Genomics Browser 2.0

Activation of MET via diverse exon 14 splicing alterations occurs in multiple tumor types and confers clinical sensitivity to MET inhibitors

Advances in the Genetics and Biology of Pancreatic Cancer

Alliance for clinical trials in oncology (ALLIANCE) trial A021501: preoperative extended chemotherapy vs. chemotherapy plus hypofractionated radiation therapy for borderline resectable adenocarcinoma of the head of the pancreas

An improved CTC isolation scheme for pairing with downstream genomics: Demonstrating clinical utility in metastatic prostate, lung and pancreatic cancer

Analytical and Clinical Validation of a Digital Sequencing Panel for Quantitative, Highly Accurate Evaluation of Cell-Free Circulating Tumor DNA

Atorvastatin prevents RhoC isoprenylation, invasion, and metastasis in human melanoma cells ⬇️

Bioluminescent imaging of melanoma in live mice

Blinded by the Light: Molecular Imaging in Pancreatic Adenocarcinoma ⬇️

Blockade of leukemia inhibitory factor as a therapeutic approach to KRAS driven pancreatic cancer

Blockchain-Authenticated Sharing of Genomic and Clinical Outcomes Data of Patients With Cancer: A Prospective Cohort Study

Brg1 promotes both tumor-suppressive and oncogenic activities at distinct stages of pancreatic cancer formation

Bringing Pancreas Cancer into the Lab

Cell of origin and mutation pattern define three clinically distinct classes of sebaceous carcinoma.

Cell-Free DNA Next-Generation Sequencing in Pancreatobiliary Carcinomas.

Circulating tumor cells in hepatocellular carcinoma: a pilot study of detection, enumeration, and next-generation sequencing in cases and controls

Clinical Sequencing Contributes to a BRCA-Associated Cancer Rediagnosis That Guides an Effective Therapeutic Course

Co-occurring Alterations in the RAS-MAPK Pathway Limit Response to MET Inhibitor Treatment in MET Exon 14 Skipping Mutation-Positive Lung Cancer

Correction: Decoupling of the PI3K Pathway via Mutation Necessitates Combinatorial Treatment in HER2+ Breast Cancer

Decoupling of the PI3K Pathway via Mutation Necessitates Combinatorial Treatment in HER2+ Breast Cancer

Distinct patterns of somatic genome alterations in lung adenocarcinomas and squamous cell carcinomas

Distinctions with a Difference: RNA Subtyping and Clinical Outcome In Pancreatic Cancer

Early Response Assessment in Pancreatic Ductal Adenocarcinoma Through Integrated PET/MRI

Election 2016: Voting on Variants.

Erratum to: Modeling precision treatment of breast cancer

Estimation of Fractional Extracellular Space at CT for Predicting Chemotherapy Response and Survival in Pancreatic Ductal Adenocarcinoma

Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression

Histology, anatomy, or geography? Exome sequencing begins to delineate somatic mutational differences in esophageal cancer.

Hybrid Capture-Based Tumor Sequencing and Copy Number Analysis to Confirm Origin of Metachronous Metastases in BRCA1-Mutant Cholangiocarcinoma Harboring a Novel YWHAZ-BRAF Fusion.

Isoprenylation is necessary for the full invasive potential of RhoA overexpression in human melanoma cells

Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma

MET Exon 14 Mutation Encodes an Actionable Therapeutic Target in Lung Adenocarcinoma

Mapping the molecular determinants of BRAF oncogene dependence in human lung cancer.

Modeling precision treatment of breast cancer

Molecular Insights in Transmission of Cancer From an Organ Donor to Four Transplant Recipients

Molecular subtypes of pancreatic cancer

Multi-faceted epigenetic dysregulation of gene expression promotes esophageal squamous cell carcinoma

Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin

Mutationally activated PIK3CA(H1047R) cooperates with BRAF(V600E) to promote lung cancer progression.

PARADIGM-SHIFT predicts the function of mutations in multiple cancers using pathway impact analysis

Pancreatic Cancer Genomics 2.0: Profiling Metastases

Pancreatic Cancer: Progress and Challenges in a Rapidly Moving Field.

Pancreatic ductal adenocarcinoma progression is restrained by stromal matrix

Phylogenetic analyses of melanoma reveal complex patterns of metastatic dissemination.

Preoperative Modified FOLFIRINOX Treatment Followed by Capecitabine-Based Chemoradiation for Borderline Resectable Pancreatic Cancer: Alliance for Clinical Trials in Oncology Trial A021101.

RADIA: RNA and DNA integrated analysis for somatic mutation detection

RAS-MAPK dependence underlies a rational polytherapy strategy in EML4-ALK-positive lung cancer.

RB and Prognosis in Resected Lung Adenocarcinoma

Ras-GTP dimers activate the Mitogen-Activated Protein Kinase (MAPK) pathway

Re: "Clinical Sequencing Contributes to a BRCA-Associated Cancer Rediagnosis That Guides an Effective Therapeutic Course".

Referral frequency, attrition rate, and outcomes of germline testing in patients with pancreatic adenocarcinoma

Single-molecule superresolution imaging allows quantitative analysis of RAF multimer formation and signaling

Stromal Content Is Correlated With Tissue Site, Contrast Retention, and Survival in Pancreatic Adenocarcinoma

Stromal cues regulate the pancreatic cancer epigenome and metabolome

Subtype and pathway specific responses to anticancer compounds in breast cancer

Subtype-specific MEK-PI3 kinase feedback as a therapeutic target in pancreatic adenocarcinoma

Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy

Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring

Temporal dissection of tumorigenesis in primary cancers

The Authors Respond

The Cancer Genome Atlas Pan-Cancer analysis project

The Hippo effector YAP promotes resistance to RAF- and MEK-targeted cancer therapies

The Role of MR Imaging in Pancreatic Cancer

Theranostic targeting of CUB domain containing protein 1 (CDCP1) in pancreatic cancer

Timing chromosomal abnormalities using mutation data.

Transcription restores DNA repair to heterochromatin, determining regional mutation rates in cancer genomes.

Treatment of metastatic melanoma with an orally available inhibitor of the Ras-Raf-MAPK cascade ⬇️

Ultrasensitive plasma ctDNA KRAS assay for detection, prognosis, and assessment of therapeutic response in patients with unresectable pancreatic ductal adenocarcinoma

Vitamin D receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy

What are we learning from the cancer genome?