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A Non-invasive Method to Assess Hepatic Acetyl-CoA In Vivo

artículo científico publicado en 2017

A feed-forward regulatory loop in adipose tissue promotes signaling by the hepatokine FGF21

artículo científico publicado en 2020

A precision medicine approach to metabolic therapy for breast cancer in mice

artículo científico publicado en 2022

Acetate mediates a microbiome-brain-β-cell axis to promote metabolic syndrome

scientific journal article

Acetyl-CoA Carboxylase Inhibition Reverses NAFLD and Hepatic Insulin Resistance but Promotes Hypertriglyceridemia in Rodents.

artículo científico publicado en 2018

Author Correction: Metformin inhibits gluconeogenesis via a redox-dependent mechanism in vivo

artículo científico publicado en 2019

Controlled-release mitochondrial protonophore (CRMP) reverses dyslipidemia and hepatic steatosis in dysmetabolic nonhuman primates

scientific article published on 01 October 2019

Controlled-release mitochondrial protonophore reverses diabetes and steatohepatitis in rats

artículo científico publicado en 2015

Deletion of the diabetes candidate gene Slc16a13 in mice attenuates diet-induced ectopic lipid accumulation and insulin resistance

artículo científico publicado en 2021

Direct assessment of hepatic mitochondrial oxidative and anaplerotic fluxes in humans using dynamic 13C magnetic resonance spectroscopy

artículo científico publicado en 2013

Dissociation of Muscle Insulin Resistance from Alterations in Mitochondrial Substrate Preference

artículo científico publicado en 2020

FGF1 and FGF19 reverse diabetes by suppression of the hypothalamic-pituitary-adrenal axis

artículo científico publicado en 2015

Genetic activation of pyruvate dehydrogenase alters oxidative substrate selection to induce skeletal muscle insulin resistance.

artículo científico publicado en 2014

Glucagon stimulates gluconeogenesis by INSP3R1-mediated hepatic lipolysis

artículo científico publicado en 2020

Hepatic acetyl CoA links adipose tissue inflammation to hepatic insulin resistance and type 2 diabetes

artículo científico publicado en 2015

Imeglimin lowers glucose primarily by amplifying glucose-stimulated insulin secretion in high-fat-fed rodents

artículo científico publicado en 2016

Imeglimin: Current Development and Future Potential in Type 2 Diabetes

artículo científico publicado en 2020

In vivo studies on the mechanism of methylene cyclopropyl acetic acid and methylene cyclopropyl glycine-induced hypoglycemia

artículo científico publicado en 2018

Leptin Mediates a Glucose-Fatty Acid Cycle to Maintain Glucose Homeostasis in Starvation

artículo científico publicado en 2017

Leptin reverses diabetes by suppression of the hypothalamic-pituitary-adrenal axis

artículo científico publicado en 2014

Mechanism for leptin's acute insulin-independent effect to reverse diabetic ketoacidosis

artículo científico publicado en 2017

Mechanisms by which a Very-Low-Calorie Diet Reverses Hyperglycemia in a Rat Model of Type 2 Diabetes

artículo científico publicado en 2017

Metabolic control analysis of hepatic glycogen synthesis in vivo

artículo científico publicado en 2020

Metformin inhibits gluconeogenesis via a redox-dependent mechanism in vivo.

artículo científico publicado en 2018

Non-invasive assessment of hepatic mitochondrial metabolism by positional isotopomer NMR tracer analysis (PINTA).

artículo científico publicado en 2017

Novel Strategies to Treat Hepatic Steatosis and Steatohepatitis

scientific article published on 25 July 2019

OGT suppresses S6K1-mediated macrophage inflammation and metabolic disturbance

scientific article published on 29 June 2020

Obesity-associated, but not obesity-independent, tumors respond to insulin by increasing mitochondrial glucose oxidation

artículo científico publicado en 2019

PP2A inhibition results in hepatic insulin resistance despite Akt2 activation

artículo científico publicado en 2013

Prevention of diet-induced hepatic steatosis and hepatic insulin resistance by second generation antisense oligonucleotides targeted to the longevity gene mIndy (Slc13a5)

artículo científico publicado en 2015

Propionate Increases Hepatic Pyruvate Cycling and Anaplerosis and Alters Mitochondrial Metabolism

artículo científico publicado en 2016

Publisher Correction: Non-invasive assessment of hepatic mitochondrial metabolism by positional isotopomer NMR tracer analysis (PINTA).

artículo científico publicado en 2018

Reply to Constantin-Teodosiu et al.: mice with genetic PDH activation are not protected from high-fat diet-induced muscle insulin resistance

artículo científico publicado en 2015

Reversal of hypertriglyceridemia, fatty liver disease, and insulin resistance by a liver-targeted mitochondrial uncoupler

artículo científico publicado en 2013

SGLT2 inhibition slows tumor growth in mice by reversing hyperinsulinemia

scientific article published on 11 December 2019

Saturated and unsaturated fat induce hepatic insulin resistance independently of TLR-4 signaling and ceramide synthesis in vivo

artículo científico publicado en 2013

Short-term overnutrition induces white adipose tissue insulin resistance through sn-1,2-diacylglycerol - PKCε - insulin receptorT1160 phosphorylation

artículo científico publicado en 2021

Sodium glucose cotransporter-2 inhibitors: Understanding the mechanisms for therapeutic promise and persisting risks

scientific article published on 12 August 2020

The Impact of Obesity on Tumor Glucose Uptake in Breast and Lung Cancer

scientific article published on 12 February 2020

The role of hepatic lipids in hepatic insulin resistance and type 2 diabetes

artículo científico publicado en 2014