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2017 Cardiovascular and Stroke Endpoint Definitions for Clinical Trials.

artículo científico publicado en 2018

2017 Cardiovascular and Stroke Endpoint Definitions for Clinical Trials.

artículo científico publicado en 2018

A combined clinical and biomarker approach to predict diuretic response in acute heart failure

artículo científico publicado en 2015

A multimarker multi-time point-based risk stratification strategy in acute heart failure: results from the RELAX-AHF trial

artículo científico publicado en 2017

A network analysis to compare biomarker profiles in patients with and without diabetes mellitus in acute heart failure

artículo científico publicado en 2017

A novel approach to improve cardiac performance: cardiac myosin activators

scientific article published on December 2009

A proposal to standardize dyspnoea measurement in clinical trials of acute heart failure syndromes: the need for a uniform approach

artículo científico publicado en 2008

A putative placebo analysis of the effects of LCZ696 on clinical outcomes in heart failure

artículo científico publicado en 2015

A rational approach for the treatment of acute heart failure: current strategies and future options

artículo científico publicado en 2004

Abnormal liver function tests in acute heart failure: relationship with clinical characteristics and outcome in the PROTECT study

artículo científico publicado en 2016

Acute Treatment With Omecamtiv Mecarbil to Increase Contractility in Acute Heart Failure: The ATOMIC-AHF Study

artículo científico publicado en 2016

Acute coronary syndromes and acute heart failure: a diagnostic dilemma and high-risk combination. A statement from the Acute Heart Failure Committee of the Heart Failure Association of the European Society of Cardiology

artículo científico publicado en 2020

Acute decompensated heart failure update

artículo científico publicado en 2015

Acute decompensated heart failure: update on new and emerging evidence and directions for future research

artículo científico publicado en 2013

Acute heart failure clinical drug development: from planning to proof of activity to phase III.

artículo científico publicado en 2010

Acute heart failure in elderly patients: worse outcomes and differential utility of standard prognostic variables. Insights from the PROTECT trial

article

Acute heart failure in the elderly: differences in clinical characteristics, outcomes, and prognostic factors in the VERITAS Study

artículo científico publicado en 2015

Acute heart failure in the young: Clinical characteristics and biomarker profiles

artículo científico publicado en 2016

Acute heart failure syndromes and coronary perfusion

artículo científico publicado en 2008

Acute heart failure: emerging from the shadows

scientific article published on 01 January 2008

Advanced (stage D) heart failure: a statement from the Heart Failure Society of America Guidelines Committee

article by James C Fang et al published 4 May 2015 in Journal of Cardiac Failure

Agents with inotropic properties for the management of acute heart failure syndromes. Traditional agents and beyond

artículo científico publicado en 2009

Agents with vasodilator properties in acute heart failure

artículo científico publicado en 2017

Angiotensin receptor neprilysin inhibition compared with enalapril on the risk of clinical progression in surviving patients with heart failure

artículo científico publicado en 2014

Application of adaptive design and decision making to a phase II trial of a phosphodiesterase inhibitor for the treatment of intermittent claudication

artículo científico publicado en 2011

Aspirin Does Not Increase Heart Failure Events in Heart Failure Patients: From the WARCEF Trial

artículo científico publicado en 2017

Assessing the lifetime benefit of heart failure therapies

scientific article published on 21 May 2020

Association between mortality and implantable cardioverter-defibrillators by aetiology of heart failure: a propensity-matched analysis of the WARCEF trial

Association of segmental wall motion abnormalities occurring during hemodialysis with post-dialysis fatigue

artículo científico publicado en 2013

Associations of Body Mass Index With Laboratory and Biomarkers in Patients With Acute Heart Failure

artículo científico

Associations of tissue Doppler imaging with NT-proBNP and hs-TnT: a pilot study in end-stage renal disease

artículo científico publicado en 2014

Benefit of cardiopoietic mesenchymal stem cell therapy on left ventricular remodelling: results from the Congestive Heart Failure Cardiopoietic Regenerative Therapy (CHART-1) study

artículo científico publicado en 2017

Benefit of warfarin compared with aspirin in patients with heart failure in sinus rhythm: a subgroup analysis of WARCEF, a randomized controlled trial

artículo científico publicado en 2013

Biased ligand of the angiotensin II type 1 receptor in patients with acute heart failure: a randomized, double-blind, placebo-controlled, phase IIB, dose ranging trial (BLAST-AHF).

artículo científico publicado en 2017

Bile salts for the treatment of heart failure: out on a limb for a gut feeling?

artículo científico publicado en 2012

Biomarker Profiles of Acute Heart Failure Patients With a Mid-Range Ejection Fraction

artículo científico publicado en 2017

Bleeding Risk and Antithrombotic Strategy in Patients With Sinus Rhythm and Heart Failure With Reduced Ejection Fraction Treated With Warfarin or Aspirin

artículo científico publicado en 2015

Blood urea nitrogen-to-creatinine ratio in the general population and in patients with acute heart failure

artículo científico

Body Weight Change During and After Hospitalization for Acute Heart Failure: Patient Characteristics, Markers of Congestion, and Outcomes: Findings From the ASCEND-HF Trial

artículo científico publicado en 2017

CHA2 DS2 -VASc score and adverse outcomes in patients with heart failure with reduced ejection fraction and sinus rhythm

artículo científico publicado en 2016

CHA2DS2-VASC SCORE AND ADVERSE EVENTS IN PATIENTS WITH HEART FAILURE AND SINUS RHYTHM

COMPARE: comparison of the effects of carvedilol CR and carvedilol IR on left ventricular ejection fraction in patients with heart failure

artículo científico publicado en 2006

Cardiac Calcitropes, Myotropes, and Mitotropes: JACC Review Topic of the Week

scientific article published on 01 May 2019

Cardiac Myosin Activation with Omecamtiv Mecarbil in Systolic Heart Failure

artículo científico publicado en 2020

Cardiac inotropes: current agents and future directions ⬇️

artículo científico publicado el 8 de marzo de 2011

Cardiac matrix metalloproteinase-2 expression independently induces marked ventricular remodeling and systolic dysfunction

artículo científico publicado en 2006

Cardiac myosin activators: up and coming.

artículo científico publicado en 2015

Cardiopoietic cell therapy for advanced ischaemic heart failure: results at 39 weeks of the prospective, randomized, double blind, sham-controlled CHART-1 clinical trial

artículo científico publicado en 2016

Cause of Death in Patients With Acute Heart Failure: Insights From RELAX-AHF-2

artículo científico publicado en 2020

Chronic Oral Study of Myosin Activation to Increase Contractility in Heart Failure (COSMIC-HF): a phase 2, pharmacokinetic, randomised, placebo-controlled trial

artículo científico publicado en 2016

Clinical Correlates and Prognostic Value of Proenkephalin in Acute and Chronic Heart Failure

artículo científico publicado en 2016

Clinical and Echocardiographic Factors Associated With New-Onset Atrial Fibrillation in Heart Failure　– Subanalysis of the WARCEF Trial –

Clinical and Research Considerations for Patients With Hypertensive Acute Heart Failure: A Consensus Statement from the Society for Academic Emergency Medicine and the Heart Failure Society of America Acute Heart Failure Working Group

artículo científico publicado en 2016

Clinical and Research Considerations for Patients With Hypertensive Acute Heart Failure: A Consensus Statement from the Society of Academic Emergency Medicine and the Heart Failure Society of America Acute Heart Failure Working Group

artículo científico publicado en 2016

Clinical development of pharmacologic agents for acute heart failure syndromes: a proposal for a mechanistic translational phase

artículo científico publicado en 2010

Clinical trials of pharmacological therapies in acute heart failure syndromes: lessons learned and directions forward

scientific article published on March 2010

Clinical value of pre-discharge bio-adrenomedullin as a marker of residual congestion and high risk of heart failure hospital readmission

scientific article published on 03 December 2019

Cognitive Decline Over Time in Patients With Systolic Heart Failure: Insights From WARCEF

artículo científico publicado en 2019

Cognitive function in ambulatory patients with systolic heart failure: insights from the warfarin versus aspirin in reduced cardiac ejection fraction (WARCEF) trial

artículo científico publicado en 2014

Combining Diuretic Response and Hemoconcentration to Predict Rehospitalization After Admission for Acute Heart Failure

artículo científico

Comparative effectiveness of torsemide versus furosemide in heart failure patients: insights from the PROTECT trial

artículo científico publicado en 2015

Comparison of pyrroloquinoline quinone and/or metoprolol on myocardial infarct size and mitochondrial damage in a rat model of ischemia/reperfusion injury

artículo científico publicado en 2006

Comparison of symptomatic and functional responses to vagus nerve stimulation in ANTHEM-HF, INOVATE-HF, and NECTAR-HF

scientific article published on 27 January 2020

Conducting clinical trials in heart failure during (and after) the COVID-19 pandemic: an Expert Consensus Position Paper from the Heart Failure Association (HFA) of the European Society of Cardiology (ESC)

scientific article published on 04 June 2020

Day vs night: Does time of presentation matter in acute heart failure? A secondary analysis from the RELAX-AHF trial

artículo científico publicado en 2017

Design considerations and proposed template for clinical trials in hospitalized patients with decompensated chronic heart failure

artículo científico publicado en 2003

Design of a "Lean" Case Report Form for Heart Failure Therapeutic Development

scientific article published on 07 August 2019

Design of the RELAXin in acute heart failure study.

artículo científico publicado en 2012

Determinants of hemodialysis-induced segmental wall motion abnormalities

artículo científico publicado en 2013

Developing therapies for heart failure with preserved ejection fraction: current state and future directions

artículo científico publicado en 2014

Direct Myosin Activation by Omecamtiv Mecarbil for Heart Failure with Reduced Ejection Fraction

artículo científico publicado en 2017

Diuretic response in acute heart failure: clinical characteristics and prognostic significance.

artículo científico publicado en 2014

Diuretic response in patients with acute decompensated heart failure: characteristics and clinical outcome--an analysis from RELAX-AHF.

artículo científico publicado en 2014

Do countries or hospitals with longer hospital stays for acute heart failure have lower readmission rates?: Findings from ASCEND-HF.

artículo científico

Dose-dependent augmentation of cardiac systolic function with the selective cardiac myosin activator, omecamtiv mecarbil: a first-in-man study

artículo científico publicado en 2011

Dyspnea as an end point in clinical trials of therapies for acute decompensated heart failure

artículo científico publicado en 2003

Dyspnoea and worsening heart failure in patients with acute heart failure: results from the Pre-RELAX-AHF study

artículo científico publicado en 2010

Dyspnoea in patients with acute heart failure: an analysis of its clinical course, determinants, and relationship to 60-day outcomes in the PROTECT pilot study

artículo científico publicado en 2010

Early drop in systolic blood pressure and worsening renal function in acute heart failure: renal results of Pre-RELAX-AHF.

artículo científico

Early dyspnoea relief in acute heart failure: prevalence, association with mortality, and effect of rolofylline in the PROTECT Study

artículo científico publicado en 2011

Early management of patients with acute heart failure: state of the art and future directions--a consensus document from the SAEM/HFSA acute heart failure working group

artículo científico publicado en 2014

Early management of patients with acute heart failure: state of the art and future directions. A consensus document from the society for academic emergency medicine/heart failure society of America acute heart failure working group

artículo científico publicado en 2015

Early vs. late worsening heart failure during acute heart failure hospitalization: insights from the PROTECT trial

artículo científico publicado en 2015

Effect of Implantable Cardioverter-Defibrillators by Etiology of Heart Failure: A Propensity-Matched Mortality Analysis of the WARCEF Trial

Effect of levosimendan on the short-term clinical course of patients with acutely decompensated heart failure.

artículo científico publicado en 2013

Effect of serelaxin on cardiac, renal, and hepatic biomarkers in the Relaxin in Acute Heart Failure (RELAX-AHF) development program: correlation with outcomes

artículo científico publicado en 2013

Effect of serelaxin on mode of death in acute heart failure: results from the RELAX-AHF study

artículo científico publicado en 2014

Effects of Serelaxin in Patients with Acute Heart Failure

scientific article published on 01 August 2019

Effects of a Novel Nitroxyl Donor in Acute Heart Failure: The STAND-UP AHF Study

scientific article published on 24 November 2020

Effects of serelaxin in acute heart failure patients with renal impairment: results from RELAX-AHF

artículo científico publicado en 2016

Effects of serelaxin in patients admitted for acute heart failure: a meta-analysis

artículo científico publicado en 2019

Effects of serelaxin in subgroups of patients with acute heart failure: results from RELAX-AHF

artículo científico publicado en 2013

Effects of serelaxin on the outcome of patients with or without substantial peripheral edema: A subgroup analysis from the RELAX-AHF trial

artículo científico publicado en 2017

Effects of tezosentan on symptoms and clinical outcomes in patients with acute heart failure: the VERITAS randomized controlled trials

artículo científico publicado en 2007

Effects of the Adenosine A1 Receptor Antagonist Rolofylline on Renal Function in Patients With Acute Heart Failure and Renal Dysfunction

article

Effects of tolvaptan on dyspnoea relief from the EVEREST trials

artículo científico publicado en 2009

Efficacy of sacubitril/valsartan vs. enalapril at lower than target doses in heart failure with reduced ejection fraction: the PARADIGM-HF trial

artículo científico publicado en 2016

Endothelins: pathophysiology and treatment implications in chronic heart failure

artículo científico publicado en 2005

Endpoints in Heart Failure Drug Development: History and Future

scientific article published on 06 April 2020

Erratum to 'The role of angiotensin receptor-neprilysin inhibitors in cardiovascular disease-existing evidence, knowledge gaps, and future directions' [Eur J Heart Fail 2018;20:963-972]

artículo científico publicado en 2019

Erratum to: Serelaxin in acute heart failure patients with and without atrial fibrillation: a secondary analysis of the RELAX-AHF trial.

artículo científico publicado en 2017

Evaluating the Efficacy, Safety, and Tolerability of Serelaxin When Added to Standard Therapy in Asian Patients With Acute Heart Failure: Design and Rationale of RELAX-AHF-ASIA Trial

artículo científico publicado en 2016

Geographic Differences in Patients in a Global Acute Heart Failure Clinical Trial (from the ASCEND-HF Trial).

artículo científico publicado en 2016

Growth differentiation factor 15 (GDF-15) in patients admitted for acute heart failure: results from the RELAX-AHF study

artículo científico publicado en 2015

HETEROGENEITY IN EFFICACY OF ROLOFYLLINE USING A RISK-BASED EVALUATION IN PATIENTS HOSPITALIZED WITH ACUTE HEART FAILURE

HFSA 2010 Comprehensive Heart Failure Practice Guideline

artículo científico publicado en 2010

Heart Failure End Points in Cardiovascular Outcome Trials of Sodium Glucose Cotransporter 2 Inhibitors in Patients With Type 2 Diabetes Mellitus: A Critical Evaluation of Clinical and Regulatory Issues

scientific article published on 16 December 2019

Heart Failure Severity and Quality of Warfarin Anticoagulation Control (From the WARCEF Trial)

Heart Failure Site-Based Research in the United States: Results of the Heart Failure Society of America Research Network Survey

scientific article published on 10 April 2019

Heart failure

artículo científico publicado en 2017

Heart failure therapeutics on the basis of a biased ligand of the angiotensin-2 type 1 receptor. Rationale and design of the BLAST-AHF study (Biased Ligand of the Angiotensin Receptor Study in Acute Heart Failure).

artículo científico

Hemodynamic and clinical effects of tezosentan, an intravenous dual endothelin receptor antagonist, in patients hospitalized for acute decompensated heart failure

artículo científico publicado en 2003

Hepatorenal dysfunction identifies high-risk patients with acute heart failure: insights from the RELAX-AHF trial

artículo científico publicado en 2019

Hospital costs for treatment of acute heart failure: economic analysis of the REVIVE II study.

artículo científico publicado en 2009

Hospitalization for Recently Diagnosed Versus Worsening Chronic Heart Failure: From the ASCEND-HF Trial

artículo científico

Hyperkalemia and Treatment With RAAS Inhibitors During Acute Heart Failure Hospitalizations and Their Association With Mortality

artículo científico publicado en 2019

Hypochloremia, Diuretic Resistance, and Outcome in Patients With Acute Heart Failure

artículo científico

Identifying Subpopulations with Distinct Response to Treatment Using Plasma Biomarkers in Acute Heart Failure: Results from the PROTECT Trial : Differential Response in Acute Heart Failure

artículo científico publicado en 2017

Impact of Autonomic Regulation Therapy in Patients with Heart Failure: ANTHEM-HFrEF Pivotal Study Design

artículo científico publicado en 2019

Impact of serial troponin release on outcomes in patients with acute heart failure: analysis from the PROTECT pilot study

artículo científico

In-hospital worsening heart failure

artículo científico

Incorporating development of a patient-reported outcome instrument in a clinical drug development program: examples from a heart failure program

artículo científico publicado en 2016

Indications for cardiac resynchronization therapy: 2011 update from the Heart Failure Society of America Guideline Committee

artículo científico publicado en 2012

Influence of Clinical Trial Site Enrollment on Patient Characteristics, Protocol Completion, and End Points: Insights From the ASCEND-HF Trial (Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure).

artículo científico

Influence of Sacubitril/Valsartan (LCZ696) on 30-Day Readmission After Heart Failure Hospitalization

artículo científico publicado en 2016

International differences in clinical characteristics, management, and outcomes in acute heart failure patients: better short-term outcomes in patients enrolled in Eastern Europe and Russia in the PROTECT trial

artículo científico publicado en 2014

Investigating pain in heart failure patients: rationale and design of the Pain Assessment, Incidence & Nature in Heart Failure (PAIN-HF) study

scientific article published on 01 May 2008

Investigating pain in heart failure patients: the pain assessment, incidence, and nature in heart failure (PAIN-HF) study

artículo científico publicado en 2012

Is Time of the Essence? The Impact of Time of Hospital Presentation in Acute Heart Failure: Insights From ASCEND-HF Trial.

artículo científico publicado en 2018

Is plasma renin activity associated with worse outcomes in acute heart failure? A secondary analysis from the BLAST-AHF trial

scientific article published on 23 October 2019

Ivabradine in heart failure--no paradigm SHIFT…yet

artículo científico publicado en 2010

Ivabradine: Role in the Chronic Heart Failure Armamentarium

artículo científico publicado en 2016

Late breaking heart failure trials from the 2003 ACC meeting: EPHESUS and COMPANION.

artículo científico publicado en 2003

Learning the points of COMPASS-HF: assessing implantable hemodynamic monitoring in heart failure patients

artículo científico publicado en 2008

Left Ventricular Ejection Fraction and Risk of Stroke and Cardiac Events in Heart Failure: Data From the Warfarin Versus Aspirin in Reduced Ejection Fraction Trial

artículo científico publicado en 2016

Left atrial volume and cardiovascular outcomes in systolic heart failure: effect of antithrombotic treatment

Left ventricular volume reduction by radiofrequency heating of chronic myocardial infarction in patients with congestive heart failure

artículo científico publicado en 2002

Letter by Teerlink et al Regarding Article, "Myosin Activator Omecamtiv Mecarbil Increases Myocardial Oxygen Consumption and Impairs Cardiac Efficiency Mediated by Resting Myosin ATPase Activity".

artículo científico publicado en 2015

Liver function tests in patients with acute heart failure and associated outcomes: insights from ASCEND-HF.

artículo científico publicado en 2015

Liver function, in-hospital, and post-discharge clinical outcome in patients with acute heart failure-results from the relaxin for the treatment of patients with acute heart failure study

artículo científico publicado en 2014

Low lymphocyte ratio as a novel prognostic factor in acute heart failure: results from the Pre-RELAX-AHF study.

artículo científico publicado en 2010

Lung ultrasound: a 'B-line' to the prediction of decompensated heart failure

artículo científico publicado en 2016

Measurement of troponin and natriuretic peptides shortly after admission in patients with heart failure-does it add useful prognostic information? An analysis of the Value of Endothelin Receptor Inhibition with Tezosentan in Acute heart failure Stud

artículo científico publicado en 2017

Medical therapy for chronic heart failure

artículo científico

Mega-trials in heart failure: effects of dilution in examination of new therapies

scientific article published on 30 March 2020

MicroRNAs relate to early worsening of renal function in patients with acute heart failure

artículo científico publicado en 2015

Mind or body: evaluating mind-body therapy efficacy in heart failure trials

artículo científico publicado en 2011

Mind the Gap: Current Challenges and Future State of Heart Failure Care

artículo científico publicado en 2017

Mode of death in patients with heart failure and a preserved ejection fraction: results from the Irbesartan in Heart Failure With Preserved Ejection Fraction Study (I-Preserve) trial

artículo científico publicado en 2010

National Heart, Lung, and Blood Institute working group on emergency department management of acute heart failure: research challenges and opportunities

artículo científico publicado en 2010

Nesiritide and worsening of renal function: the emperor's new clothes?

artículo científico publicado en 2005

Nesiritide: a reappraisal of efficacy and safety

artículo científico publicado en 2007

Neurohormonal activation in acute heart failure: results from VERITAS.

artículo científico publicado en 2011

Not time to RELAX in acute heart failure - Authors' reply

artículo científico publicado en 2013

Novel Pharmacologic Therapy of Heart Failure

artículo científico publicado en 2003

Novel drug mechanisms in development for heart failure

artículo científico publicado en 2014

Omecamtiv Mecarbil in Chronic Heart Failure with Reduced Ejection Fraction, GALACTIC-HF: Baseline Characteristics and Comparison with Contemporary Clinical Trials

artículo científico publicado en 2020

Omecamtiv Mecarbil in Chronic Heart Failure With Reduced Ejection Fraction: Rationale and Design of GALACTIC-HF

scientific article published on 06 February 2020

Omecamtiv mecarbil: a new cardiac myosin activator for the treatment of heart failure

artículo científico publicado en 2015

Optimizing clinical use of biomarkers in high-risk acute heart failure patients

artículo científico publicado en 2015

Overview of randomized clinical trials in acute heart failure syndromes

artículo científico publicado en 2005

Patient and Facility Variation in Costs of VA Heart Failure Patients

artículo científico publicado en 2016

Patient journey after admission for acute heart failure: length of stay, 30-day readmission and 90-day mortality

artículo científico

Patient-Reported Outcome Instruments in Heart Failure: Are They Preserved?

artículo científico publicado en 2018

Patient-Reported Outcomes in Chronic Heart Failure: Applicability for Regulatory Approval

artículo científico publicado en 2016

Permutation criteria to evaluate multiple clinical endpoints in a proof-of-concept study: lessons from Pre-RELAX-AHF

artículo científico publicado en 2011

Pharmacology of new agents for acute heart failure syndromes

artículo científico publicado en 2005

Phase III clinical trial end points in acute heart failure syndromes: A virtual roundtable with the acute heart failure syndromes international working group

article

Plasma biomarkers to predict or rule out early post-discharge events after hospitalization for acute heart failure

artículo científico publicado en 2017

Plasma kidney injury molecule-1 in heart failure: renal mechanisms and clinical outcome

artículo científico publicado en 2015

Predictors and Associations With Outcomes of Length of Hospital Stay in Patients With Acute Heart Failure: Results From VERITAS.

artículo científico

Predictors of clinical outcomes in acute decompensated heart failure: Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure outcome models

artículo científico

Predictors of early dyspnoea relief in acute heart failure and the association with 30-day outcomes: findings from ASCEND-HF.

artículo científico publicado en 2012

Predictors of postdischarge outcomes from information acquired shortly after admission for acute heart failure: a report from the Placebo-Controlled Randomized Study of the Selective A1 Adenosine Receptor Antagonist Rolofylline for Patients Hospital

artículo científico publicado en 2013

Prevalence, predictors and clinical outcome of residual congestion in acute decompensated heart failure.

artículo científico publicado en 2018

Procalcitonin-based indication of bacterial infection identifies high risk acute heart failure patients

artículo científico publicado en 2015

Prognostic Significance of Creatinine Increases During an Acute Heart Failure Admission in Patients With and Without Residual Congestion

Pulse pressure and prognosis in patients with heart failure with reduced ejection fraction

scientific article published on 23 February 2019

Pyrroloquinoline quinone (PQQ) decreases myocardial infarct size and improves cardiac function in rat models of ischemia and ischemia/reperfusion

artículo científico publicado en 2004

QUALITY OF LIFE 60 DAYS AFTER AN ACUTE HEART FAILURE EVENT: INSIGHTS FROM THE PROTECT TRIAL

Quality of anticoagulation control in preventing adverse events in patients with heart failure in sinus rhythm: Warfarin versus Aspirin in Reduced Cardiac Ejection Fraction trial substudy

artículo científico publicado en 2015

Rate pressure product and the components of heart rate and systolic blood pressure in hospitalized heart failure patients with preserved ejection fraction: Insights from ASCEND-HF

scientific article published on 17 July 2018

Rationale and design for the development of a novel nitroxyl donor in patients with acute heart failure

artículo científico publicado en 2019

Reassessing Phase II Heart Failure Clinical Trials: Consensus Recommendations

artículo científico publicado en 2017

Reassessing the Role of Surrogate End Points in Drug Development for Heart Failure

article

Recent heart failure trials of neurohormonal modulation (OVERTURE and ENABLE): approaching the asymptote of efficacy?

artículo científico publicado en 2002

Recurrent stroke in the warfarin versus aspirin in reduced cardiac ejection fraction (WARCEF) trial

artículo científico publicado en 2014

Relationship between baseline systolic blood pressure and long-term outcomes in acute heart failure patients treated with TRV027: an exploratory subgroup analysis of BLAST-AHF.

artículo científico publicado en 2017

Relationship between left ventricular ejection fraction and cardiovascular outcomes following hospitalization for heart failure: insights from the RELAX-AHF-2 trial

artículo científico publicado en 2020

Relaxin for the treatment of patients with acute heart failure (Pre-RELAX-AHF): a multicentre, randomised, placebo-controlled, parallel-group, dose-finding phase IIb study.

artículo científico publicado en 2009

Relaxin, a pleiotropic vasodilator for the treatment of heart failure.

artículo científico publicado en 2009

Relaxin: review of biology and potential role in treating heart failure

artículo científico publicado en 2010

Renal function trajectories and clinical outcomes in acute heart failure

artículo científico publicado en 2013

Reply: Mode of Death Prevention by Serelaxin

artículo científico publicado en 2015

Resting Heart Rate and Ischemic Stroke in Patients with Heart Failure

artículo científico publicado en 2017

Reversal of left ventricular remodeling: role of the endothelin pathway

artículo científico publicado en 2002

Risk-based evaluation of efficacy of rolofylline in patients hospitalized with acute heart failure - Post-hoc analysis of the PROTECT trial

artículo científico publicado en 2016

Role of tolvaptan in acute decompensated heart failure

artículo científico publicado en 2008

Rolofylline, an adenosine A1-receptor antagonist, in acute heart failure

artículo científico publicado en 2010

Running from her past: a case of rapidly progressive dyspnea on exertion

artículo científico publicado en 2011

Screening for Sleep-Disordered Breathing in Patients Hospitalized for Heart Failure.

artículo científico publicado en 2015

Serelaxin : a potential new drug for the treatment of acute heart failure

artículo científico

Serelaxin and acute heart failure

artículo científico publicado en 2015

Serelaxin in acute heart failure patients with and without atrial fibrillation: a secondary analysis of the RELAX-AHF trial

artículo científico publicado en 2017

Serelaxin in acute heart failure patients with preserved left ventricular ejection fraction: results from the RELAX-AHF trial

artículo científico publicado en 2013

Serelaxin in addition to standard therapy in acute heart failure: rationale and design of the RELAX-AHF-2 study

artículo científico publicado en 2017

Serelaxin, recombinant human relaxin-2, for treatment of acute heart failure (RELAX-AHF): a randomised, placebo-controlled trial

artículo científico publicado en 2012

Serial high sensitivity cardiac troponin T measurement in acute heart failure: insights from the RELAX-AHF study

artículo científico publicado en 2015

Serum Potassium Levels and Outcome in Acute Heart Failure (Data from the PROTECT and COACH Trials).

artículo científico publicado en 2016

Sex differences in early dyspnea relief between men and women hospitalized for acute heart failure: insights from the RELAX-AHF study

artículo científico publicado en 2016

Sex-specific acute heart failure phenotypes and outcomes from PROTECT.

artículo científico publicado en 2013

Signature of circulating microRNAs in patients with acute heart failure

artículo científico publicado en 2015

Site enrollment rate, outcomes, and study drug effects in a multicenter trial. Results from RELAX-AHF.

artículo científico publicado en 2018

Site selection in global clinical trials in patients hospitalized for heart failure: perceived problems and potential solutions

artículo científico publicado en 2014

Strategies to prevent postdischarge adverse events among hospitalized patients with heart failure

artículo científico publicado en 2013

Stroke in heart failure in sinus rhythm: the Warfarin versus Aspirin in Reduced Cardiac Ejection Fraction trial

artículo científico publicado en 2013

Sudden cardiac death after acute heart failure hospital admission: insights from ASCEND-HF.

artículo científico publicado en 2017

Surrogate end points in heart failure trials

artículo científico publicado en 2003

Systolic blood pressure reduction during the first 24 h in acute heart failure admission: friend or foe?

artículo científico publicado en 2017

Systolic time intervals in patients with heart failure: time to teach new dogs old tricks

scientific article published on 13 February 2020

TAILORING THERAPY IN ACUTE HEART FAILURE: CAN BIOMARKERS DISTINGUISH RESPONDERS FROM NON-RESPONDERS?

Team-based Care for Patients Hospitalized with Heart Failure

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Tezosentan in patients with acute heart failure and acute coronary syndromes: results of the Randomized Intravenous TeZosentan Study (RITZ-4).

artículo científico publicado en 2003

Tezosentan in patients with acute heart failure: design of the Value of Endothelin Receptor Inhibition with Tezosentan in Acute heart failure Study (VERITAS).

artículo científico publicado en 2005

The Hospitalization Burden and Post-Hospitalization Mortality Risk in Heart Failure With Preserved Ejection Fraction: Results From the I-PRESERVE Trial (Irbesartan in Heart Failure and Preserved Ejection Fraction).

artículo científico publicado en 2015

The PROTECT in-hospital risk model: 7-day outcome in patients hospitalized with acute heart failure and renal dysfunction

artículo científico publicado en 2012

The addition of angiotensin receptor blockers to angiotensin-converting enzyme inhibitors--what has time told us?

artículo científico publicado en 2005

The clinical effects of levosimendan are not attenuated by sulfonylureas

artículo científico publicado en 2012

The development of new medical treatments for acute decompensated heart failure.

artículo científico publicado en 2002

The effects of the cardiac myosin activator, omecamtiv mecarbil, on cardiac function in systolic heart failure: a double-blind, placebo-controlled, crossover, dose-ranging phase 2 trial.

artículo científico publicado en 2011

The first prognostic model for stroke and death in patients with systolic heart failure

artículo científico publicado en 2015

The predictive value of short-term changes in hemoglobin concentration in patients presenting with acute decompensated heart failure

artículo científico publicado en 2013

The role of angiotensin receptor-neprilysin inhibitors in cardiovascular disease-existing evidence, knowledge gaps, and future directions

artículo científico publicado en 2018

The role of endothelin in the pathogenesis of heart failure

artículo científico publicado en 2002

The safety of an adenosine A(1)-receptor antagonist, rolofylline, in patients with acute heart failure and renal impairment: findings from PROTECT.

artículo científico publicado en 2012

The safety of sacubitril-valsartan for the treatment of chronic heart failure

artículo científico publicado en 2017

Trajectories of Changes in Renal Function in Patients with Acute Heart Failure

scientific article published on 15 July 2019

Treatment of HF in an Era of Multiple Therapies: Statement From the HF Collaboratory

scientific article published on 09 December 2020

Treatment with 24 hour istaroxime infusion in patients hospitalised for acute heart failure: a randomised, placebo-controlled trial

artículo científico publicado en 2020

Ultrafiltration is associated with fewer rehospitalizations than continuous diuretic infusion in patients with decompensated heart failure: results from UNLOAD.

artículo científico publicado en 2010

Ultrafiltration versus intravenous diuretics for patients hospitalized for acute decompensated heart failure.

artículo científico publicado en 2007

Update on Aldosterone Antagonists Use in Heart Failure With Reduced Left Ventricular Ejection Fraction Heart Failure Society of America Guidelines Committee

artículo científico publicado en 2012

Update on the Management of Acute Decompensated Heart Failure

artículo científico publicado en 2011

Use of High-Sensitivity Troponin T to Identify Patients With Acute Heart Failure at Lower Risk for Adverse Outcomes: An Exploratory Analysis From the RELAX-AHF Trial

artículo científico publicado en 2016

Use of biomarkers to establish potential role and function of circulating microRNAs in acute heart failure.

artículo científico publicado en 2016

Utility of Impedance Cardiography for the Identification of Short-Term Risk of Clinical Decompensation in Stable Patients With Chronic Heart Failure

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Vasodilators in the treatment of acute heart failure: what we know, what we don't

artículo científico publicado en 2009

Ventricular remodeling surgery for heart failure: small animals and how to measure an improvement in ventricular function

scientific article published on 01 May 2002

Warfarin and aspirin in patients with heart failure and sinus rhythm

artículo científico publicado en 2012

What's Next for Acute Heart Failure Research?

artículo científico publicado en 2017

What's new in the treatment of acute heart failure?

artículo científico

Why has positive inotropy failed in chronic heart failure? Lessons from prior inotrope trials

artículo científico publicado en 2019

Worsening Heart Failure Following Admission for Acute Heart Failure: A Pooled Analysis of the PROTECT and RELAX-AHF Studies

artículo científico publicado en 2015

Worsening heart failure, a critical event during hospital admission for acute heart failure: results from the VERITAS study

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