Lista de obras -

A key role for mast cell chymase in the activation of pro-matrix metalloprotease-9 and pro-matrix metalloprotease-2.

artículo científico publicado en 2004

A role for cathepsin E in the processing of mast-cell carboxypeptidase A.

artículo científico publicado en 2005

A role for serglycin proteoglycan in granular retention and processing of mast cell secretory granule components

scientific journal article

A role for serglycin proteoglycan in mast cell apoptosis induced by a secretory granule-mediated pathway.

artículo científico publicado en 2010

ADAMTS: novel proteases expressed by activated mast cells

artículo científico publicado en 2013

Ablation of human skin mast cells in situ by lysosomotropic agents.

artículo científico publicado en 2015

Accumulation of Ym1 and formation of intracellular crystalline bodies in alveolar macrophages lacking heparanase

artículo científico publicado en 2010

Acidic pH is essential for maintaining mast cell secretory granule homeostasis

artículo científico publicado en 2017

Activated mast cells promote differentiation of B cells into effector cells.

artículo científico publicado en 2016

Active Caspase-3 Is Stored within Secretory Compartments of Viable Mast Cells ⬇️

artículo científico publicado el 1 de agosto de 2013

Age-related enlargement of lymphoid tissue and altered leukocyte composition in serglycin-deficient mice

article

Altered storage of proteases in mast cells from mice lacking heparin: a possible role for heparin in carboxypeptidase A processing

artículo científico publicado en 2002

Approaches for analyzing the roles of mast cells and their proteases in vivo

artículo científico publicado en 2015

Biological implications of preformed mast cell mediators ⬇️

artículo científico publicado el 11 de noviembre de 2010

Biology of mast cell tryptase. An inflammatory mediator

artículo científico publicado en 2006

Canine uterine bacterial infection induces upregulation of proteolysis-related genes and downregulation of homeobox and zinc finger factors

artículo científico publicado en 2009

Chymase inhibitor-sensitive synthesis of endothelin-1 (1-31) by recombinant mouse mast cell protease 4 and human chymase.

artículo científico publicado en 2015

Cooperation between mast cell carboxypeptidase A and the chymase mouse mast cell protease 4 in the formation and degradation of angiotensin II

scientific journal article

Copper Regulates Maturation and Expression of an MITF:Tryptase Axis in Mast Cells.

artículo científico publicado en 2017

Correction to: Glutamate triggers the expression of functional ionotropic and metabotropic glutamate receptors in mast cells

artículo científico publicado en 2020

Critical role of mast cell chymase in mouse abdominal aortic aneurysm formation

artículo científico publicado en 2009

Ctr2 Regulates Mast Cell Maturation by Affecting the Storage and Expression of Tryptase and Proteoglycans

artículo científico publicado en 2015

DNA demethylation regulates gene expression in IgE-activated mouse mast cells

scientific article published on 29 January 2020

Damnacanthal inhibits IgE receptor-mediated activation of mast cells

artículo científico publicado en 2015

Delayed contraction of the CD8+ T cell response toward lymphocytic choriomeningitis virus infection in mice lacking serglycin

scientific journal article

Differential regulation of Nr4a subfamily nuclear receptors following mast cell activation ⬇️

artículo científico publicado el 31 de mayo de 2011

Distorted secretory granule composition in mast cells with multiple protease deficiency

artículo científico publicado en 2013

Diverse bone morphogenetic protein expression profiles and smad pathway activation in different phenotypes of experimental canine mammary tumors

artículo científico publicado en 2009

Do Mast Cells Have a Role in Tendon Healing and Inflammation?

scientific article published on 04 May 2020

Dual targets for mouse mast cell protease-4 in mediating tissue damage in experimental bullous pemphigoid

artículo científico publicado en 2011

Endothelin receptor antagonist macitentan or deletion of mouse mast cell protease 4 delays lesion development in atherosclerotic mice

artículo científico publicado en 2016

Excessive dietary intake of vitamin A reduces skull bone thickness in mice

artículo científico publicado en 2017

Exosome-mediated uptake of mast cell tryptase into the nucleus of melanoma cells: a novel axis for regulating tumor cell proliferation and gene expression

scientific article published on 10 September 2019

Experimental Autoimmune Encephalomyelitis Potentiates Mouse Mast Cell Protease 4-Dependent Pressor Responses to Centrally or Systemically Administered Big Endothelin-1

scientific article published on 27 June 2019

Extended substrate specificity of rat mast cell protease 5, a rodent alpha-chymase with elastase-like primary specificity

scientific journal article

Extensive expression of craniofacial related homeobox genes in canine mammary sarcomas

artículo científico publicado en 2008

Glioma-derived macrophage migration inhibitory factor (MIF) promotes mast cell recruitment in a STAT5-dependent manner

artículo científico publicado en 2013

Glutamate triggers the expression of functional ionotropic and metabotropic glutamate receptors in mast cells

scientific article published on 20 April 2020

Granzyme D is a novel murine mast cell protease that is highly induced by multiple pathways of mast cell activation

artículo científico publicado en 2013

Granzyme H is a novel protease expressed by human mast cells

artículo científico publicado en 2014

Heparanase affects secretory granule homeostasis of murine mast cells through degrading heparin ⬇️

artículo científico publicado el 14 de mayo de 2011

Histidines are critical for heparin-dependent activation of mast cell tryptase

artículo científico publicado en 2004

Histone Methyltransferase Inhibition Has a Cytotoxic Impact on Transformed Mast Cells: Implications for Mastocytosis

scientific article published on 01 May 2020

Human mast cell beta-tryptase is a gelatinase

artículo científico publicado en 2003

IGF-1 degradation by mouse mast cell protease 4 promotes cell death and adverse cardiac remodeling days after a myocardial infarction

artículo científico publicado en 2016

IL-6 and IL-17A degradation by mast cells is mediated by a serglycin:serine protease axis

artículo científico publicado en 2015

Increased Bone Mass in Female Mice Lacking Mast Cell Chymase

artículo científico publicado en 2016

Increased levels of hypoxia-sensitive proteins in allergic airway inflammation

artículo científico publicado en 2004

Increased mast cell degranulation and co-localization of mast cells with the NMDA receptor-1 during healing after Achilles tendon rupture.

artículo científico publicado en 2017

Induction of Human Lung Mast Cell Apoptosis by Granule Permeabilization: A Novel Approach for Targeting Mast Cells

artículo científico publicado en 2017

Induction of Mast Cell Apoptosis by a Novel Secretory Granule-Mediated Pathway

artículo científico publicado en 2015

Infection of mast cells with live streptococci causes a toll-like receptor 2- and cell-cell contact-dependent cytokine and chemokine response

artículo científico publicado en 2009

Inhibition of the BET family of epigenetic reader proteins: A novel principle for modulating gene expression in IgE-activated mast cells

artículo científico publicado en 2017

Live Staphylococcus aureus Induces Expression and Release of Vascular Endothelial Growth Factor in Terminally Differentiated Mouse Mast Cells

scientific article published on 23 June 2016

Lysosomotropic challenge of mast cells causes intra-granular reactive oxygen species production

artículo científico publicado en 2019

Mast Cell Chymase Decreases The Severity Of Group B Streptococcus Infections

artículo científico publicado en 2017

Mast Cell Degranulation Exacerbates Skin Rejection by Enhancing Neutrophil Recruitment

Mast Cell β-Tryptase Is Enzymatically Stabilized by DNA

scientific article published on 17 July 2020

Mast Cells and MCPT4 Chymase Promote Renal Impairment after Partial Ureteral Obstruction.

artículo científico publicado en 2017

Mast cell accumulation in glioblastoma with a potential role for stem cell factor and chemokine CXCL12.

artículo científico publicado en 2011

Mast cell apoptosis induced by siramesine, a sigma-2 receptor agonist

artículo científico publicado en 2012

Mast cell cathepsins C and S control levels of carboxypeptidase A and the chymase, mouse mast cell protease 5.

artículo científico publicado en 2003

Mast cell chymase contributes to the antibody response and the severity of autoimmune arthritis

artículo científico publicado en 2008

Mast cell chymase protects against acute ischemic kidney injury by limiting neutrophil hyperactivation and recruitment

artículo científico publicado en 2019

Mast cell chymase protects against renal fibrosis in murine unilateral ureteral obstruction

artículo científico publicado en 2013

Mast cell chymase reduces the toxicity of Gila monster venom, scorpion venom, and vasoactive intestinal polypeptide in mice

artículo científico publicado en 2011

Mast cell differentiation and activation is closely linked to expression of genes coding for the serglycin proteoglycan core protein and a distinct set of chondroitin sulfate and heparin sulfotransferases

artículo científico publicado en 2009

Mast cell proteases

artículo científico publicado en 2007

Mast cell proteases: multifaceted regulators of inflammatory disease

artículo científico publicado en 2010

Mast cell secretory granules: armed for battle

artículo científico publicado en 2014

Mast cell-dependent activation of pro matrix metalloprotease 2: A role for serglycin proteoglycan-dependent mast cell proteases

scientific journal article

Mast cells are activated by Staphylococcus aureus in vitro but do not influence the outcome of intraperitoneal S. aureus infection in vivo

artículo científico publicado en 2014

Mast cells can enhance resistance to snake and honeybee venoms

artículo científico publicado en 2006

Mast cells contribute to bleomycin-induced lung inflammation and injury in mice through a chymase/mast cell protease 4-dependent mechanism

artículo científico publicado en 2014

Mast cells express tyrosine hydroxylase and store dopamine in a serglycin-dependent manner ⬇️

artículo científico publicado el 1 de enero de 2012

Mast cells limit extracellular levels of IL-13 via a serglycin proteoglycan-serine protease axis.

artículo científico publicado en 2012

Mast cells promote melanoma colonization of lungs

artículo científico publicado en 2016

Mast cells promote scar remodeling and functional recovery after spinal cord injury via mouse mast cell protease 6.

artículo científico publicado en 2016

Mast cells protect from post-traumatic brain inflammation by the mast cell-specific chymase mouse mast cell protease-4.

artículo científico publicado en 2012

Mast cells protect from post-traumatic spinal cord damage in mice by degrading inflammation-associated cytokines via mouse mast cell protease 4.

artículo científico publicado en 2013

Mast cells regulate homeostatic intestinal epithelial migration and barrier function by a chymase/Mcpt4-dependent mechanism

artículo científico publicado en 2009

Mastitis Pathogens with High Virulence in a Mouse Model Produce a Distinct Cytokine Profile In Vivo.

artículo científico publicado en 2016

Mefloquine, an anti-malaria agent, causes reactive oxygen species-dependent cell death in mast cells via a secretory granule-mediated pathway

artículo científico publicado en 2014

Mitogen-Activated Protein Kinase Signaling Regulates Proteoglycan Composition of Mast Cell Secretory Granules.

artículo científico publicado en 2018

Mouse Mast Cell Protease 4 Deletion Protects Heart Function and Survival After Permanent Myocardial Infarction

scholarly article by Martin Houde et al published 2018 in Frontiers in Pharmacology

Mouse Mast Cell Protease-4 Recruits Leukocytes in the Inflammatory Phase of Surgically Wounded Skin

scientific article published on 21 August 2019

Mouse connective tissue mast cell proteases tryptase and carboxypeptidase A3 play protective roles in itch induced by endothelin-1

scientific article published on 22 April 2020

Mouse mast cell protease 4 is the major chymase in murine airways and has a protective role in allergic airway inflammation

artículo científico publicado en 2009

Mouse mast cell protease 4 suppresses scar formation after traumatic spinal cord injury

scientific article published on 06 March 2019

Mouse mast cell protease-4 deteriorates renal function by contributing to inflammation and fibrosis in immune complex-mediated glomerulonephritis

artículo científico publicado en 2010

Mouse mast cell proteases 4 and 5 mediate epidermal injury through disruption of tight junctions

scientific article published on 12 February 2014

Neurotensin increases mortality and mast cells reduce neurotensin levels in a mouse model of sepsis

artículo científico publicado en 2008

Neutrophil elastase depends on serglycin proteoglycan for localization in granules

artículo científico publicado en 2007

Novel Insight into the in vivo Function of Mast Cell Chymase: Lessons from Knockouts and Inhibitors

scientific article published on 04 June 2020

Novel aspects of mast cell and basophil function: Highlights from the 9th meeting of the European Mast Cell and Basophil Research Network (EMBRN)-A Marcus Wallenberg Symposium

scientific article published on 18 October 2019

Novel insights into the biological function of mast cell carboxypeptidase A.

artículo científico publicado en 2009

Nuclear receptor 4a3 (nr4a3) regulates murine mast cell responses and granule content

scientific journal article

Pivotal role of mouse mast cell protease 4 in the conversion and pressor properties of Big-endothelin-1.

artículo científico publicado en 2013

Polyamines are present in mast cell secretory granules and are important for granule homeostasis

artículo científico publicado en 2010

Polycationic peptides as inhibitors of mast cell serine proteases

artículo científico publicado en 2003

Protective role of mouse mast cell tryptase Mcpt6 in melanoma

artículo científico publicado en 2020

Proteolytic histone modification by mast cell tryptase, a serglycin proteoglycan-dependent secretory granule protease

artículo científico publicado en 2014

Proteome analysis of mast cell releasates reveals a role for chymase in the regulation of coagulation factor XIIIA levels via proteolytic degradation.

artículo científico publicado en 2016

Quantitative In-Depth Analysis of the Mouse Mast Cell Transcriptome Reveals Organ-Specific Mast Cell Heterogeneity

artículo científico publicado en 2020

Rat mast cell protease 4 is a beta-chymase with unusually stringent substrate recognition profile

scientific journal article

Reduction with dithiothreitol causes serglycin-specific defects in secretory granule integrity of bone marrow derived mast cells

artículo científico publicado en 2008

Secretion of macrophage urokinase plasminogen activator is dependent on proteoglycans ⬇️

artículo científico publicado el 1 de octubre de 2003

Serglycin Is a Major Proteoglycan in Polarized Human Endothelial Cells and Is Implicated in the Secretion of the Chemokine GROα/CXCL1 ⬇️

artículo científico publicado el 12 de noviembre de 2010

Serglycin Proteoglycan Promotes Apoptotic versus Necrotic Cell Death in Mast Cells ⬇️

artículo científico publicado el 9 de abril de 2012

Serglycin determines secretory granule repertoire and regulates natural killer cell and cytotoxic T lymphocyte cytotoxicity.

artículo científico publicado en 2016

Serglycin is essential for maturation of mast cell secretory granule

scientific journal article

Serglycin is the major secreted proteoglycan in macrophages and has a role in the regulation of macrophage tumor necrosis factor-alpha secretion in response to lipopolysaccharide

scientific journal article

Serglycin protects against high fat diet-induced increase in serum LDL in mice

scientific article published on 21 September 2015

Serglycin proteoglycan deletion induces defects in platelet aggregation and thrombus formation in mice

artículo científico publicado en 2007

Serglycin proteoglycan is not implicated in localizing exocrine pancreas enzymes to zymogen granules.

artículo científico publicado en 2009

Serglycin proteoglycan is required for secretory granule integrity in mucosal mast cells

artículo científico publicado en 2007

Serglycin proteoglycan: regulating the storage and activities of hematopoietic proteases

artículo científico publicado en 2009

Serglycin-deficient cytotoxic T lymphocytes display defective secretory granule maturation and granzyme B storage

scientific journal article

Serglycin: The Master of the Mast Cell ⬇️

artículo científico publicado el 1 de enero de 2012

Serotonin and histamine storage in mast cell secretory granules is dependent on serglycin proteoglycan

artículo científico publicado en 2008

Significant Contribution of Mouse Mast Cell Protease 4 in Early Phases of Experimental Autoimmune Encephalomyelitis

artículo científico publicado en 2016

Streptococcal sagA activates a proinflammatory response in mast cells by a sublytic mechanism

scientific article published on 07 July 2019

The Absence of Tryptase Mcpt6 Causes Elevated Cellular Stress in Response to Modulation of the Histone Acetylation Status in Mast Cells

scientific article published on 02 October 2019

The Effect of Lipopolysaccharide-Induced Experimental Bovine Mastitis on Clinical Parameters, Inflammatory Markers, and the Metabolome: A Kinetic Approach.

artículo científico publicado en 2018

The Role of Mast Cells in Bacterial Infection

artículo científico

The chymase mouse mast cell protease 4 degrades TNF, limits inflammation, and promotes survival in a model of sepsis

artículo científico publicado en 2012

The chymase, mouse mast cell protease 4, constitutes the major chymotrypsin-like activity in peritoneum and ear tissue. A role for mouse mast cell protease 4 in thrombin regulation and fibronectin turnover

scientific journal article

The combined action of mast cell chymase, tryptase and carboxypeptidase A3 protects against melanoma colonization of the lung

artículo científico publicado en 2017

The controversial role of mast cells in fibrosis

artículo científico publicado en 2018

The emerging role of mast cell proteases in asthma

artículo científico publicado en 2019

The inflammatory response after an epidermal burn depends on the activities of mouse mast cell proteases 4 and 5.

artículo científico publicado en 2010

The role of mouse mast cell proteases in the proliferative phase of wound healing in microdeformational wound therapy

artículo científico publicado en 2014

Tryptase-catalyzed core histone truncation: A novel epigenetic regulatory mechanism in mast cells

artículo científico publicado en 2017

Tumor–mast cell interactions: Induction of pro-tumorigenic genes and anti-tumorigenic 4-1BB in MCs in response to Lewis Lung Carcinoma ⬇️

artículo científico publicado el 18 de febrero de 2012

Urticaria: Collegium Internationale Allergologicum (CIA) Update 2020

artículo científico publicado en 2020

Vitamin a is a negative regulator of osteoblast mineralization

artículo científico publicado en 2013

[EXPRESS] Mouse mast cells and mast cell proteases do not play a significant role in acute tissue injury pain induced by formalin

artículo científico publicado en 2018

[The mast cell--both evil and good. Time to reconsider the role of the mast cell in health and disease]

artículo científico publicado en 2009

Lista de obras de

A key role for mast cell chymase in the activation of pro-matrix metalloprotease-9 and pro-matrix metalloprotease-2.

A role for cathepsin E in the processing of mast-cell carboxypeptidase A.

A role for serglycin proteoglycan in granular retention and processing of mast cell secretory granule components

A role for serglycin proteoglycan in mast cell apoptosis induced by a secretory granule-mediated pathway.

ADAMTS: novel proteases expressed by activated mast cells

Ablation of human skin mast cells in situ by lysosomotropic agents.

Accumulation of Ym1 and formation of intracellular crystalline bodies in alveolar macrophages lacking heparanase

Acidic pH is essential for maintaining mast cell secretory granule homeostasis

Activated mast cells promote differentiation of B cells into effector cells.

Active Caspase-3 Is Stored within Secretory Compartments of Viable Mast Cells ⬇️

Age-related enlargement of lymphoid tissue and altered leukocyte composition in serglycin-deficient mice

Altered storage of proteases in mast cells from mice lacking heparin: a possible role for heparin in carboxypeptidase A processing

Approaches for analyzing the roles of mast cells and their proteases in vivo

Biological implications of preformed mast cell mediators ⬇️

Biology of mast cell tryptase. An inflammatory mediator

Canine uterine bacterial infection induces upregulation of proteolysis-related genes and downregulation of homeobox and zinc finger factors

Chymase inhibitor-sensitive synthesis of endothelin-1 (1-31) by recombinant mouse mast cell protease 4 and human chymase.

Cooperation between mast cell carboxypeptidase A and the chymase mouse mast cell protease 4 in the formation and degradation of angiotensin II

Copper Regulates Maturation and Expression of an MITF:Tryptase Axis in Mast Cells.

Correction to: Glutamate triggers the expression of functional ionotropic and metabotropic glutamate receptors in mast cells

Critical role of mast cell chymase in mouse abdominal aortic aneurysm formation

Ctr2 Regulates Mast Cell Maturation by Affecting the Storage and Expression of Tryptase and Proteoglycans

DNA demethylation regulates gene expression in IgE-activated mouse mast cells

Damnacanthal inhibits IgE receptor-mediated activation of mast cells

Delayed contraction of the CD8+ T cell response toward lymphocytic choriomeningitis virus infection in mice lacking serglycin

Differential regulation of Nr4a subfamily nuclear receptors following mast cell activation ⬇️

Distorted secretory granule composition in mast cells with multiple protease deficiency

Diverse bone morphogenetic protein expression profiles and smad pathway activation in different phenotypes of experimental canine mammary tumors

Do Mast Cells Have a Role in Tendon Healing and Inflammation?

Dual targets for mouse mast cell protease-4 in mediating tissue damage in experimental bullous pemphigoid

Endothelin receptor antagonist macitentan or deletion of mouse mast cell protease 4 delays lesion development in atherosclerotic mice

Excessive dietary intake of vitamin A reduces skull bone thickness in mice

Exosome-mediated uptake of mast cell tryptase into the nucleus of melanoma cells: a novel axis for regulating tumor cell proliferation and gene expression

Experimental Autoimmune Encephalomyelitis Potentiates Mouse Mast Cell Protease 4-Dependent Pressor Responses to Centrally or Systemically Administered Big Endothelin-1

Extended substrate specificity of rat mast cell protease 5, a rodent alpha-chymase with elastase-like primary specificity

Extensive expression of craniofacial related homeobox genes in canine mammary sarcomas

Glioma-derived macrophage migration inhibitory factor (MIF) promotes mast cell recruitment in a STAT5-dependent manner

Glutamate triggers the expression of functional ionotropic and metabotropic glutamate receptors in mast cells

Granzyme D is a novel murine mast cell protease that is highly induced by multiple pathways of mast cell activation

Granzyme H is a novel protease expressed by human mast cells

Heparanase affects secretory granule homeostasis of murine mast cells through degrading heparin ⬇️

Histidines are critical for heparin-dependent activation of mast cell tryptase

Histone Methyltransferase Inhibition Has a Cytotoxic Impact on Transformed Mast Cells: Implications for Mastocytosis

Human mast cell beta-tryptase is a gelatinase

IGF-1 degradation by mouse mast cell protease 4 promotes cell death and adverse cardiac remodeling days after a myocardial infarction

IL-6 and IL-17A degradation by mast cells is mediated by a serglycin:serine protease axis

Increased Bone Mass in Female Mice Lacking Mast Cell Chymase

Increased levels of hypoxia-sensitive proteins in allergic airway inflammation

Increased mast cell degranulation and co-localization of mast cells with the NMDA receptor-1 during healing after Achilles tendon rupture.

Induction of Human Lung Mast Cell Apoptosis by Granule Permeabilization: A Novel Approach for Targeting Mast Cells

Induction of Mast Cell Apoptosis by a Novel Secretory Granule-Mediated Pathway

Infection of mast cells with live streptococci causes a toll-like receptor 2- and cell-cell contact-dependent cytokine and chemokine response

Inhibition of the BET family of epigenetic reader proteins: A novel principle for modulating gene expression in IgE-activated mast cells

Live Staphylococcus aureus Induces Expression and Release of Vascular Endothelial Growth Factor in Terminally Differentiated Mouse Mast Cells

Lysosomotropic challenge of mast cells causes intra-granular reactive oxygen species production

Mast Cell Chymase Decreases The Severity Of Group B Streptococcus Infections

Mast Cell Degranulation Exacerbates Skin Rejection by Enhancing Neutrophil Recruitment

Mast Cell β-Tryptase Is Enzymatically Stabilized by DNA

Mast Cells and MCPT4 Chymase Promote Renal Impairment after Partial Ureteral Obstruction.

Mast cell accumulation in glioblastoma with a potential role for stem cell factor and chemokine CXCL12.

Mast cell apoptosis induced by siramesine, a sigma-2 receptor agonist

Mast cell cathepsins C and S control levels of carboxypeptidase A and the chymase, mouse mast cell protease 5.

Mast cell chymase contributes to the antibody response and the severity of autoimmune arthritis

Mast cell chymase protects against acute ischemic kidney injury by limiting neutrophil hyperactivation and recruitment

Mast cell chymase protects against renal fibrosis in murine unilateral ureteral obstruction

Mast cell chymase reduces the toxicity of Gila monster venom, scorpion venom, and vasoactive intestinal polypeptide in mice

Mast cell differentiation and activation is closely linked to expression of genes coding for the serglycin proteoglycan core protein and a distinct set of chondroitin sulfate and heparin sulfotransferases

Mast cell proteases

Mast cell proteases: multifaceted regulators of inflammatory disease

Mast cell secretory granules: armed for battle

Mast cell-dependent activation of pro matrix metalloprotease 2: A role for serglycin proteoglycan-dependent mast cell proteases

Mast cells are activated by Staphylococcus aureus in vitro but do not influence the outcome of intraperitoneal S. aureus infection in vivo

Mast cells can enhance resistance to snake and honeybee venoms

Mast cells contribute to bleomycin-induced lung inflammation and injury in mice through a chymase/mast cell protease 4-dependent mechanism

Mast cells express tyrosine hydroxylase and store dopamine in a serglycin-dependent manner ⬇️

Mast cells limit extracellular levels of IL-13 via a serglycin proteoglycan-serine protease axis.

Mast cells promote melanoma colonization of lungs

Mast cells promote scar remodeling and functional recovery after spinal cord injury via mouse mast cell protease 6.

Mast cells protect from post-traumatic brain inflammation by the mast cell-specific chymase mouse mast cell protease-4.