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Bortezomib-mediated down-regulation of telomerase and disruption of telomere homeostasis contributes to apoptosis of malignant cells

artículo científico publicado en 2015

Dysregulation of shelterin factors coupled with telomere shortening in Philadelphia chromosome negative myeloproliferative neoplasms

artículo científico publicado en 2015

GABPA is a master regulator of luminal identity and restrains aggressive diseases in bladder cancer

scientific article published on 04 December 2019

GABPA-activated TGFBR2 transcription inhibits aggressiveness but is epigenetically erased by oncometabolites in renal cell carcinoma

artículo científico publicado en 2022

Genetic and epigenetic background and protein expression profiles in relation to telomerase activation in medullary thyroid carcinoma

artículo científico publicado en 2016

Histone demethylase JMJD2B is required for tumor cell proliferation and survival and is overexpressed in gastric cancer

artículo científico publicado el 19 de noviembre de 2011

Immature dendritic cells kill ovarian carcinoma cells by a FAS/FASL pathway, enabling them to sensitize tumor-specific CTLs

artículo científico publicado el 1 de noviembre de 2001

MYC-dependent downregulation of telomerase by FLT3 inhibitors is required for their therapeutic efficacy on acute myeloid leukemia

artículo científico publicado en 2017

Maternal infection of SARS-CoV-2 during the first and second trimesters leads to newborn telomere shortening

artículo científico publicado en 2024

Multidrug resistance phenotype in leukaemic cells from patients with acute myelocytic leukaemia can be detected with 99Tcm-MIBI

artículo científico publicado el 1 de junio de 1998

PLEKHS1 Over-Expression is Associated with Metastases and Poor Outcomes in Papillary Thyroid Carcinoma

artículo científico publicado en 2020

Premature senescence of T cells in long-term survivors of renal transplantation

artículo científico publicado el 21 de marzo de 2011

Promoter polymorphism in the serotonin transporter (5-HTT) gene is significantly associated with leukocyte telomere length in Han Chinese

artículo científico publicado en 2014

Telomerase Reverse Transcriptase (TERT) in Action: Cross-Talking with Epigenetics

scientific article published on 07 July 2019

Telomerase activity and the expression of telomerase components in acute myelogenous leukaemia

artículo científico publicado el 1 de septiembre de 1998

Telomerase reverse transcriptase inhibition stimulates cyclooxygenase 2 expression in cancer cells and synergizes with celecoxib to exert anti-cancer effects

artículo científico publicado el 16 de mayo de 2013

Telomerase reverse transcriptase regulates DNMT3B expression/aberrant DNA methylation phenotype and AKT activation in hepatocellular carcinoma

artículo científico publicado en 2018

The telomerase gene polymorphisms, but not telomere length, increase susceptibility to primary glomerulonephritis/end stage renal diseases in females

scientific article published on 04 May 2020

WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERThigh Prostate Cancer Stem Cells

artículo científico publicado en 2017