Lista de obras - John Lusingu - Dominio Público Uruguay

3D7-Derived Plasmodium falciparum erythrocyte membrane protein 1 is a frequent target of naturally acquired antibodies recognizing protein domains in a particular pattern independent of malaria transmission intensity

artículo científico publicado en 2007

A combined analysis of immunogenicity, antibody kinetics and vaccine efficacy from phase 2 trials of the RTS,S malaria vaccine

artículo científico publicado en 2014

A phase 3 trial of RTS,S/AS01 malaria vaccine in African infants

artículo científico publicado en 2012

A progressive declining in the burden of malaria in north-eastern Tanzania

artículo científico publicado en 2010

A semi-automated multiplex high-throughput assay for measuring IgG antibodies against Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) domains in small volumes of plasma

artículo científico publicado en 2008

Accuracy of malaria rapid diagnostic tests in community studies and their impact on treatment of malaria in an area with declining malaria burden in north-eastern Tanzania

artículo científico publicado en 2011

Acquisition of antibodies to merozoite surface protein 3 among residents of Korogwe, north eastern Tanzania

artículo científico publicado en 2010

Aetiology of acute febrile episodes in children attending Korogwe District Hospital in north-eastern Tanzania

artículo científico publicado en 2014

Biomarkers of Plasmodium falciparum infection during pregnancy in women living in northeastern Tanzania.

artículo científico publicado en 2012

Bloodstream bacterial infection among outpatient children with acute febrile illness in north-eastern Tanzania

artículo científico publicado en 2015

Community perception on biomedical research: A case study of malariometric survey in Korogwe District, Tanga Region, Tanzania

artículo científico publicado en 2014

Community perceptions on the secondary health benefits established by malaria vaccine trials (RTS,S phase 2 and phase 3) at the Korogwe site in North Eastern Tanzania ⬇️

artículo científico publicado el 8 de mayo de 2013

Cytophilic antibodies to Plasmodium falciparum glutamate rich protein are associated with malaria protection in an area of holoendemic transmission

artículo científico publicado en 2005

Development of a fetal weight chart using serial trans-abdominal ultrasound in an East African population: a longitudinal observational study

artículo científico publicado en 2012

Differences in human antibody reactivity to Plasmodium falciparum variant surface antigens are dependent on age and malaria transmission intensity in northeastern Tanzania

artículo científico publicado en 2008

Effect of ingested human antibodies induced by RTS, S/AS01 malaria vaccination in children on Plasmodium falciparum oocyst formation and sporogony in mosquitoes

artículo científico publicado en 2014

Effect of the pre-erythrocytic candidate malaria vaccine RTS,S/AS01E on blood stage immunity in young children ⬇️

artículo científico publicado en 2011

Efficacy of RTS,S malaria vaccines: individual-participant pooled analysis of phase 2 data

artículo científico publicado en 2013

Efficacy of RTS,S/AS01E vaccine against malaria in children 5 to 17 months of age

artículo científico publicado en 2008

Engaging diverse communities participating in clinical trials: case examples from across Africa

artículo científico publicado en 2010

Estimates of burden and consequences of infants born small for gestational age in low and middle income countries with INTERGROWTH-21st standard: analysis of CHERG datasets

artículo científico publicado en 2017

Estimating Annual Fluctuations in Malaria Transmission Intensity and in the Use of Malaria Control Interventions in Five Sub-Saharan African Countries

scientific article published on 21 September 2020

Evidence for in vitro and in vivo expression of the conserved VAR3 (type 3) plasmodium falciparum erythrocyte membrane protein 1.

artículo científico publicado en 2012

Factors associated with and causes of perinatal mortality in northeastern Tanzania.

artículo científico publicado en 2012

Five-year surveillance of molecular markers of Plasmodium falciparum antimalarial drug resistance in Korogwe District, Tanzania: accumulation of the 581G mutation in the P. falciparum dihydropteroate synthase gene.

artículo científico publicado en 2009

Geographical and temporal conservation of antibody recognition of Plasmodium falciparum variant surface antigens

artículo científico publicado en 2004

Haplotypes of the endothelial protein C receptor (EPCR) gene are not associated with severe malaria in Tanzania

artículo científico publicado en 2015

High efficacy of anti DBL4ɛ-VAR2CSA antibodies in inhibition of CSA-binding Plasmodium falciparum-infected erythrocytes from pregnant women

artículo científico publicado en 2010

Identification and characterization of B-cell epitopes in the DBL4ε domain of VAR2CSA

artículo científico publicado en 2012

IgG antibodies to endothelial protein C receptor-binding cysteine-rich interdomain region domains of Plasmodium falciparum erythrocyte membrane protein 1 are acquired early in life in individuals exposed to malaria

artículo científico publicado en 2015

Immunogenicity of the RTS,S/AS01 malaria vaccine and implications for duration of vaccine efficacy: secondary analysis of data from a phase 3 randomised controlled trial

artículo científico publicado en 2015

Immunoglobulin G antibody reactivity to a group A Plasmodium falciparum erythrocyte membrane protein 1 and protection from P. falciparum malaria

artículo científico publicado en 2007

Independent origin of plasmodium falciparum antifolate super-resistance, Uganda, Tanzania, and Ethiopia

artículo científico publicado en 2014

Insect cells are superior to Escherichia coli in producing malaria proteins inducing IgG targeting PfEMP1 on infected erythrocytes

artículo científico publicado en 2010

Levels of plasma immunoglobulin G with specificity against the cysteine-rich interdomain regions of a semiconserved Plasmodium falciparum erythrocyte membrane protein 1, VAR4, predict protection against malarial anemia and febrile episodes

artículo científico publicado en 2006

Limited cross-reactivity among domains of the Plasmodium falciparum clone 3D7 erythrocyte membrane protein 1 family

artículo científico publicado en 2006

Malaria and fetal growth alterations in the 3(rd) trimester of pregnancy: a longitudinal ultrasound study

artículo científico publicado en 2013

Malaria morbidity and immunity among residents of villages with different Plasmodium falciparum transmission intensity in North-Eastern Tanzania

artículo científico publicado en 2004

Malaria, malnutrition, and birthweight: A meta-analysis using individual participant data

artículo científico

Maternal Malaria and Malnutrition (M3) initiative, a pooled birth cohort of 13 pregnancy studies in Africa and the Western Pacific

artículo científico publicado en 2016

Multiple var2csa-type PfEMP1 genes located at different chromosomal loci occur in many Plasmodium falciparum isolates

artículo científico publicado en 2009

National and regional estimates of term and preterm babies born small for gestational age in 138 low-income and middle-income countries in 2010.

artículo científico publicado en 2013

Neonatal mortality risk associated with preterm birth in East Africa, adjusted by weight for gestational age: individual participant level meta-analysis

artículo científico publicado en 2012

Occurrence of pfatpase6 Single Nucleotide Polymorphisms Associated with Artemisinin Resistance among Field Isolates of Plasmodium falciparum in North-Eastern Tanzania

artículo científico publicado en 2015

Occurrence of the Southeast Asian/South American SVMNT haplotype of the chloroquine-resistance transporter gene in Plasmodium falciparum in Tanzania

artículo científico publicado en 2006

Parasite threshold associated with clinical malaria in areas of different transmission intensities in north eastern Tanzania

artículo científico publicado en 2009

Performance of rapid diagnostic test, blood-film microscopy and PCR for the diagnosis of malaria infection among febrile children from Korogwe District, Tanzania

artículo científico publicado en 2016

Peripheral blood cell signatures of Plasmodium falciparum infection during pregnancy

artículo científico publicado en 2012

Plasmodium falciparum associated with severe childhood malaria preferentially expresses PfEMP1 encoded by group A var genes

artículo científico publicado en 2004

Plasmodium falciparum erythrocyte membrane protein 1 domain cassettes 8 and 13 are associated with severe malaria in children

artículo científico publicado en 2012

Plasmodium falciparum expressing domain cassette 5 type PfEMP1 (DC5-PfEMP1) bind PECAM1.

artículo científico publicado en 2013

Plasmodium falciparum mutant haplotype infection during pregnancy associated with reduced birthweight, Tanzania

artículo científico publicado en 2013

Plasmodium falciparum var genes expressed in children with severe malaria encode CIDRα1 domains

artículo científico publicado en 2016

Prevalence of single nucleotide polymorphisms in the Plasmodium falciparum multidrug resistance gene (Pfmdr-1) in Korogwe District in Tanzania before and after introduction of artemisinin-based combination therapy

artículo científico publicado en 2011

Profile of C-reactive protein, white cells and neutrophil populations in febrile children from rural north-eastern Tanzania

artículo científico publicado en 2017

Rapid screening for glucose-6-phosphate dehydrogenase deficiency and haemoglobin polymorphisms in Africa by a simple high-throughput SSOP-ELISA method

artículo científico publicado en 2005

Reduced risk of uncomplicated malaria episodes in children with alpha+-thalassemia in northeastern Tanzania

artículo científico publicado en 2008

Relationships between sickle cell trait, malaria, and educational outcomes in Tanzania

artículo científico publicado en 2017

Reliability of rapid diagnostic tests in diagnosing pregnancy-associated malaria in north-eastern Tanzania.

artículo científico publicado en 2012

Safety of the malaria vaccine candidate, RTS,S/AS01E in 5 to 17 month old Kenyan and Tanzanian Children

artículo científico publicado en 2010

Safety profile of the RTS,S/AS01 malaria vaccine in infants and children: additional data from a phase III randomized controlled trial in sub-Saharan Africa

artículo científico publicado en 2019

Satisfactory safety and immunogenicity of MSP3 malaria vaccine candidate in tanzanian children aged 12-24 months

artículo científico publicado en 2009

Serological evidence of discrete spatial clusters of Plasmodium falciparum parasites

artículo científico publicado en 2011

Severe malaria is associated with parasite binding to endothelial protein C receptor

artículo científico publicado en 2013

Spatial variation and socio-economic determinants of Plasmodium falciparum infection in northeastern Tanzania

artículo científico publicado en 2011

Structural conservation despite huge sequence diversity allows EPCR binding by the PfEMP1 family implicated in severe childhood malaria

artículo científico publicado en 2014

The Severity of Plasmodium falciparum Infection Is Associated with Transcript Levels of var Genes Encoding Endothelial Protein C Receptor-Binding P. falciparum Erythrocyte Membrane Protein 1.

artículo científico publicado en 2017

VAR2CSA expression on the surface of placenta-derived Plasmodium falciparum-infected erythrocytes

artículo científico publicado en 2008

Lista de obras de John Lusingu

3D7-Derived Plasmodium falciparum erythrocyte membrane protein 1 is a frequent target of naturally acquired antibodies recognizing protein domains in a particular pattern independent of malaria transmission intensity

A combined analysis of immunogenicity, antibody kinetics and vaccine efficacy from phase 2 trials of the RTS,S malaria vaccine

A phase 3 trial of RTS,S/AS01 malaria vaccine in African infants

A progressive declining in the burden of malaria in north-eastern Tanzania

A semi-automated multiplex high-throughput assay for measuring IgG antibodies against Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) domains in small volumes of plasma

Accuracy of malaria rapid diagnostic tests in community studies and their impact on treatment of malaria in an area with declining malaria burden in north-eastern Tanzania

Acquisition of antibodies to merozoite surface protein 3 among residents of Korogwe, north eastern Tanzania

Aetiology of acute febrile episodes in children attending Korogwe District Hospital in north-eastern Tanzania

Biomarkers of Plasmodium falciparum infection during pregnancy in women living in northeastern Tanzania.

Bloodstream bacterial infection among outpatient children with acute febrile illness in north-eastern Tanzania

Community perception on biomedical research: A case study of malariometric survey in Korogwe District, Tanga Region, Tanzania

Community perceptions on the secondary health benefits established by malaria vaccine trials (RTS,S phase 2 and phase 3) at the Korogwe site in North Eastern Tanzania ⬇️

Cytophilic antibodies to Plasmodium falciparum glutamate rich protein are associated with malaria protection in an area of holoendemic transmission

Development of a fetal weight chart using serial trans-abdominal ultrasound in an East African population: a longitudinal observational study

Differences in human antibody reactivity to Plasmodium falciparum variant surface antigens are dependent on age and malaria transmission intensity in northeastern Tanzania

Effect of ingested human antibodies induced by RTS, S/AS01 malaria vaccination in children on Plasmodium falciparum oocyst formation and sporogony in mosquitoes

Effect of the pre-erythrocytic candidate malaria vaccine RTS,S/AS01E on blood stage immunity in young children ⬇️

Efficacy of RTS,S malaria vaccines: individual-participant pooled analysis of phase 2 data

Efficacy of RTS,S/AS01E vaccine against malaria in children 5 to 17 months of age

Engaging diverse communities participating in clinical trials: case examples from across Africa

Estimates of burden and consequences of infants born small for gestational age in low and middle income countries with INTERGROWTH-21st standard: analysis of CHERG datasets

Estimating Annual Fluctuations in Malaria Transmission Intensity and in the Use of Malaria Control Interventions in Five Sub-Saharan African Countries

Evidence for in vitro and in vivo expression of the conserved VAR3 (type 3) plasmodium falciparum erythrocyte membrane protein 1.

Factors associated with and causes of perinatal mortality in northeastern Tanzania.

Five-year surveillance of molecular markers of Plasmodium falciparum antimalarial drug resistance in Korogwe District, Tanzania: accumulation of the 581G mutation in the P. falciparum dihydropteroate synthase gene.

Geographical and temporal conservation of antibody recognition of Plasmodium falciparum variant surface antigens

Haplotypes of the endothelial protein C receptor (EPCR) gene are not associated with severe malaria in Tanzania

High efficacy of anti DBL4ɛ-VAR2CSA antibodies in inhibition of CSA-binding Plasmodium falciparum-infected erythrocytes from pregnant women

Identification and characterization of B-cell epitopes in the DBL4ε domain of VAR2CSA

IgG antibodies to endothelial protein C receptor-binding cysteine-rich interdomain region domains of Plasmodium falciparum erythrocyte membrane protein 1 are acquired early in life in individuals exposed to malaria

Immunogenicity of the RTS,S/AS01 malaria vaccine and implications for duration of vaccine efficacy: secondary analysis of data from a phase 3 randomised controlled trial

Immunoglobulin G antibody reactivity to a group A Plasmodium falciparum erythrocyte membrane protein 1 and protection from P. falciparum malaria

Independent origin of plasmodium falciparum antifolate super-resistance, Uganda, Tanzania, and Ethiopia

Insect cells are superior to Escherichia coli in producing malaria proteins inducing IgG targeting PfEMP1 on infected erythrocytes

Levels of plasma immunoglobulin G with specificity against the cysteine-rich interdomain regions of a semiconserved Plasmodium falciparum erythrocyte membrane protein 1, VAR4, predict protection against malarial anemia and febrile episodes

Limited cross-reactivity among domains of the Plasmodium falciparum clone 3D7 erythrocyte membrane protein 1 family

Malaria and fetal growth alterations in the 3(rd) trimester of pregnancy: a longitudinal ultrasound study

Malaria morbidity and immunity among residents of villages with different Plasmodium falciparum transmission intensity in North-Eastern Tanzania

Malaria, malnutrition, and birthweight: A meta-analysis using individual participant data

Maternal Malaria and Malnutrition (M3) initiative, a pooled birth cohort of 13 pregnancy studies in Africa and the Western Pacific

Multiple var2csa-type PfEMP1 genes located at different chromosomal loci occur in many Plasmodium falciparum isolates

National and regional estimates of term and preterm babies born small for gestational age in 138 low-income and middle-income countries in 2010.

Neonatal mortality risk associated with preterm birth in East Africa, adjusted by weight for gestational age: individual participant level meta-analysis

Occurrence of pfatpase6 Single Nucleotide Polymorphisms Associated with Artemisinin Resistance among Field Isolates of Plasmodium falciparum in North-Eastern Tanzania

Occurrence of the Southeast Asian/South American SVMNT haplotype of the chloroquine-resistance transporter gene in Plasmodium falciparum in Tanzania

Parasite threshold associated with clinical malaria in areas of different transmission intensities in north eastern Tanzania

Performance of rapid diagnostic test, blood-film microscopy and PCR for the diagnosis of malaria infection among febrile children from Korogwe District, Tanzania

Peripheral blood cell signatures of Plasmodium falciparum infection during pregnancy

Plasmodium falciparum associated with severe childhood malaria preferentially expresses PfEMP1 encoded by group A var genes

Plasmodium falciparum erythrocyte membrane protein 1 domain cassettes 8 and 13 are associated with severe malaria in children

Plasmodium falciparum expressing domain cassette 5 type PfEMP1 (DC5-PfEMP1) bind PECAM1.

Plasmodium falciparum mutant haplotype infection during pregnancy associated with reduced birthweight, Tanzania

Plasmodium falciparum var genes expressed in children with severe malaria encode CIDRα1 domains

Prevalence of single nucleotide polymorphisms in the Plasmodium falciparum multidrug resistance gene (Pfmdr-1) in Korogwe District in Tanzania before and after introduction of artemisinin-based combination therapy

Profile of C-reactive protein, white cells and neutrophil populations in febrile children from rural north-eastern Tanzania

Rapid screening for glucose-6-phosphate dehydrogenase deficiency and haemoglobin polymorphisms in Africa by a simple high-throughput SSOP-ELISA method

Reduced risk of uncomplicated malaria episodes in children with alpha+-thalassemia in northeastern Tanzania

Relationships between sickle cell trait, malaria, and educational outcomes in Tanzania

Reliability of rapid diagnostic tests in diagnosing pregnancy-associated malaria in north-eastern Tanzania.

Safety of the malaria vaccine candidate, RTS,S/AS01E in 5 to 17 month old Kenyan and Tanzanian Children

Safety profile of the RTS,S/AS01 malaria vaccine in infants and children: additional data from a phase III randomized controlled trial in sub-Saharan Africa

Satisfactory safety and immunogenicity of MSP3 malaria vaccine candidate in tanzanian children aged 12-24 months

Serological evidence of discrete spatial clusters of Plasmodium falciparum parasites

Severe malaria is associated with parasite binding to endothelial protein C receptor

Spatial variation and socio-economic determinants of Plasmodium falciparum infection in northeastern Tanzania

Structural conservation despite huge sequence diversity allows EPCR binding by the PfEMP1 family implicated in severe childhood malaria

The Severity of Plasmodium falciparum Infection Is Associated with Transcript Levels of var Genes Encoding Endothelial Protein C Receptor-Binding P. falciparum Erythrocyte Membrane Protein 1.

VAR2CSA expression on the surface of placenta-derived Plasmodium falciparum-infected erythrocytes