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Analysis of AKT and ERK1/2 protein kinases in extracellular vesicles isolated from blood of patients with cancer.

artículo científico publicado en 2014

Analysis of SecA2-dependent substrates in Mycobacterium marinum identifies protein kinase G (PknG) as a virulence effector.

artículo científico publicado en 2013

Cancer cells copy migratory behavior and exchange signaling networks via extracellular vesicles

scientific article published on 14 June 2018

Cell surface proteomics identifies glucose transporter type 1 and prion protein as candidate biomarkers for colorectal adenoma-to-carcinoma progression.

artículo científico publicado en 2011

Cellular imaging using matrix-enhanced and metal-assisted SIMS.

artículo científico publicado en 2010

Changes in the urinary extracellular vesicle proteome are associated with nephronophthisis-related ciliopathies

artículo científico publicado en 2018

Colorectal cancer candidate biomarkers identified by tissue secretome proteome profiling

artículo científico publicado en 2014

Colorectal cancer derived organotypic spheroids maintain essential tissue characteristics but adapt their metabolism in culture

artículo científico publicado en 2014

Combined Expression of Plasma Thrombospondin-2 and CA19-9 for Diagnosis of Pancreatic Cancer and Distal Cholangiocarcinoma: A Proteome Approach

artículo científico publicado en 2020

Comparative protein profiling reveals minichromosome maintenance (MCM) proteins as novel potential tumor markers for meningiomas

artículo científico publicado en 2010

Comparison of the performance of two affinity depletion spin filters for quantitative proteomics of CSF: Evaluation of sensitivity and reproducibility of CSF analysis using GeLC-MS/MS and spectral counting

artículo científico

Composition of the type VII secretion system membrane complex.

artículo científico publicado en 2012

Constitutively active GSK3β as a means to bolster dendritic cell functionality in the face of tumour-mediated immune suppression

scientific article published on 19 July 2019

Correction: Quantifying exosome secretion from single cells reveals a modulatory role for GPCR signaling.

artículo científico publicado en 2018

DPHL: A DIA Pan-human Protein Mass Spectrometry Library for Robust Biomarker Discovery

scientific article published on 11 August 2020

Decoration of outer membrane vesicles with multiple antigens by using an autotransporter approach

artículo científico publicado en 2014

Differential detergent extraction of mycobacterium marinum cell envelope proteins identifies an extensively modified threonine-rich outer membrane protein with channel activity.

artículo científico publicado en 2013

Direct molecular imaging of Lymnaea stagnalis nervous tissue at subcellular spatial resolution by mass spectrometry.

artículo científico publicado en 2005

Direct visualization by cryo-EM of the mycobacterial capsular layer: a labile structure containing ESX-1-secreted proteins

artículo científico publicado en 2010

EspH is a hypervirulence factor for Mycobacterium marinum and essential for the secretion of the ESX-1 substrates EspE and EspF

artículo científico publicado en 2018

Essential Role of the ESX-5 Secretion System in Outer Membrane Permeability of Pathogenic Mycobacteria

artículo científico publicado en 2015

Evaluation of a tyrosine kinase peptide microarray for tyrosine kinase inhibitor therapy selection in cancer

artículo científico publicado en 2016

Evaluation of different phospho-tyrosine antibodies for label-free phosphoproteomics

artículo científico publicado en 2015

Exosomal ITGA3 interferes with non-cancerous prostate cell functions and is increased in urine exosomes of metastatic prostate cancer patients

artículo científico publicado en 2013

Exosomal sorting of the viral oncoprotein LMP1 is restrained by TRAF2 association at signalling endosomes

artículo científico publicado en 2015

Exosomes Secreted by Apoptosis-Resistant Acute Myeloid Leukemia (AML) Blasts Harbor Regulatory Network Proteins Potentially Involved in Antagonism of Apoptosis

artículo científico publicado en 2016

Exploration of the platelet proteome in patients with early-stage cancer.

artículo científico publicado en 2018

Feasibility of label-free phosphoproteomics and application to base-line signaling of colorectal cancer cell lines.

artículo científico

Feasibility of phosphoproteomics to uncover oncogenic signalling in secreted extracellular vesicles using glioblastoma-EGFRVIII cells as a model

artículo científico publicado en 2020

Feasibility of urinary extracellular vesicle proteome profiling using a robust and simple, clinically applicable isolation method

artículo científico publicado en 2017

Genome-wide siRNA Screen Identifies the Radiosensitizing Effect of Downregulation of MASTL and FOXM1 in NSCLC.

artículo científico publicado en 2015

Gold-enhanced biomolecular surface imaging of cells and tissue by SIMS and MALDI mass spectrometry

artículo científico publicado en 2006

High-throughput and targeted in-depth mass spectrometry-based approaches for biofluid profiling and biomarker discovery

artículo científico publicado en 2007

Human Testis Phosphoproteome Reveals Kinases as Potential Targets in Spermatogenesis and Testicular Cancer

scientific article published on 25 January 2019

INKA, an integrative data analysis pipeline for phosphoproteomic inference of active kinases

artículo científico publicado en 2019

INKA, an integrative data analysis pipeline for phosphoproteomic inference of active kinases

artículo científico publicado en 2019

Identification of differentially expressed splice variants by the proteogenomic pipeline Splicify

artículo científico publicado en 2017

Identification of novel cerebrospinal fluid biomarker candidates for dementia with Lewy bodies: a proteomic approach

scientific article published on 18 June 2020

Imaging mass spectrometry at cellular length scales

artículo científico publicado en 2007

Integrating Phenotypic Search and Phosphoproteomic Profiling of Active Kinases for Optimization of Drug Mixtures for RCC Treatment

artículo científico publicado en 2020

Interaction between KDELR2 and HSP47 as a Key Determinant in Osteogenesis Imperfecta Caused by Bi-allelic Variants in KDELR2

artículo científico publicado en 2020

Interaction of 14-3-3 proteins with the estrogen receptor alpha F domain provides a drug target interface

artículo científico publicado en 2013

Kinase Inhibitor Treatment of Patients with Advanced Cancer Results in High Tumor Drug Concentrations and in Specific Alterations of the Tumor Phosphoproteome

artículo científico publicado en 2020

Label-free mass spectrometry-based proteomics for biomarker discovery and validation

artículo científico

MicroRNA-124 and -137 cooperativity controls caspase-3 activity through BCL2L13 in hippocampal neural stem cells

artículo científico publicado en 2015

Molecular characterization of colorectal adenomas reveals POFUT1 as a candidate driver of tumor progression

artículo científico publicado en 2019

Multi-omics profile of the mouse dentate gyrus after kainic acid-induced status epilepticus

artículo científico publicado en 2016

Multidrug-resistant transporter expression does not always result in drug resistance

artículo científico publicado en 2018

Mutations in ppe38 block PE_PGRS secretion and increase virulence of Mycobacterium tuberculosis

artículo científico publicado en 2018

Mycosins Are Required for the Stabilization of the ESX-1 and ESX-5 Type VII Secretion Membrane Complexes

artículo científico publicado en 2016

Novel Stool-Based Protein Biomarkers for Improved Colorectal Cancer Screening: A Case-Control Study.

artículo científico publicado en 2017

Novel diagnostic cerebrospinal fluid biomarkers for pathologic subtypes of frontotemporal dementia identified by proteomics.

artículo científico publicado en 2016

Omics Analysis of Educated Platelets in Cancer and Benign Disease of the Pancreas

artículo científico publicado en 2020

On the beta-binomial model for analysis of spectral count data in label-free tandem mass spectrometry-based proteomics

artículo científico publicado en 2009

Optimized Combination of HDACI and TKI Efficiently Inhibits Metabolic Activity in Renal Cell Carcinoma and Overcomes Sunitinib Resistance

artículo científico publicado en 2020

Optimized low-dose combinatorial drug treatment boosts selectivity and efficacy of colorectal carcinoma treatment

scientific article published on 05 October 2020

PPIB mutations cause severe osteogenesis imperfecta

artículo científico publicado en 2009

Peptide-mediated ‘miniprep’ isolation of extracellular vesicles is suitable for high-throughput proteomics.

artículo científico publicado en 2016

Phosphotyrosine-based phosphoproteomics for target identification and drug response prediction in AML cell lines

artículo científico publicado en 2020

Phosphotyrosine-based-phosphoproteomics scaled-down to biopsy level for analysis of individual tumor biology and treatment selection

artículo científico publicado en 2017

Proteins in stool as biomarkers for non-invasive detection of colorectal adenomas with high risk of progression

scientific article published on 13 January 2020

Proteome analysis of non-small cell lung cancer cell line secretomes and patient sputum reveals biofluid biomarker candidates for cisplatin response prediction

artículo científico publicado en 2019

Proteomic Analysis of miR-195 and miR-497 Replacement Reveals Potential Candidates that Increase Sensitivity to Oxaliplatin in MSI/P53wt Colorectal Cancer Cells

scientific article published on 19 September 2019

Proteomic analysis of cerebrospinal fluid extracellular vesicles: a comprehensive dataset

artículo científico publicado en 2014

Proteomic analysis of gemcitabine-resistant pancreatic cancer cells reveals that microtubule-associated protein 2 upregulation associates with taxane treatment

scientific article published on 10 May 2019

Proteomic and Functional Studies Reveal Detyrosinated Tubulin as Treatment Target in Sarcomere Mutation-Induced Hypertrophic Cardiomyopathy

artículo científico publicado en 2021

Proteomic profiling of Mycobacterium tuberculosis identifies nutrient-starvation-responsive toxin-antitoxin systems

artículo científico

Proteomics of differential extraction fractions enriched for chromatin-binding proteins from colon adenoma and carcinoma tissues.

artículo científico

Proteomics of genetically engineered mouse mammary tumors identifies fatty acid metabolism members as potential predictive markers for cisplatin resistance

artículo científico publicado en 2013

Proteomics of mouse BRCA1-deficient mammary tumors identifies DNA repair proteins with potential diagnostic and prognostic value in human breast cancer

artículo científico publicado en 2012

Proteomics of the TRAP-induced platelet releasate

artículo científico publicado en 2008

Proximal fluid proteome profiling of mouse colon tumors reveals biomarkers for early diagnosis of human colorectal cancer.

artículo científico publicado en 2012

Quantifying exosome secretion from single cells reveals a modulatory role for GPCR signaling.

artículo científico publicado en 2018

Quantitative analysis of CDX2 protein expression improves its clinical utility as a prognostic biomarker in stage II and III colon cancer

artículo científico publicado en 2020

Re-assessment of the high-grade serous ovarian cancer phosphoproteome - Identification of kinase candidates in TCGA tumors for future clinical intervention

Secretome proteomics reveals candidate non-invasive biomarkers of BRCA1 deficiency in breast cancer

scientific article published on 23 August 2016

Sensing of latent EBV infection through exosomal transfer of 5'pppRNA

artículo científico publicado en 2016

Specific chaperones for the type VII protein secretion pathway.

artículo científico publicado en 2012

Standardization and harmonization of distributed multi-center proteotype analysis supporting precision medicine studies

artículo científico publicado en 2020

Strategies for kinome profiling in cancer and potential clinical applications: chemical proteomics and array-based methods

artículo científico publicado en 2010

Subcellular imaging mass spectrometry of brain tissue.

artículo científico publicado en 2005

Subnuclear proteomics in colorectal cancer: identification of proteins enriched in the nuclear matrix fraction and regulation in adenoma to carcinoma progression.

artículo científico

Sunitinib activates Axl signaling in renal cell cancer.

artículo científico

The Hippo Pathway Transducers YAP1/TEAD Induce Acquired Resistance to Trastuzumab in HER2-Positive Breast Cancer

scientific article published on 29 April 2020

The proteome of the locus ceruleus in Parkinson's disease: relevance to pathogenesis

artículo científico publicado en 2011

The secretome of colon cancer stem cells contains drug-metabolizing enzymes

artículo científico publicado en 2013

Tools and strategies for visualization of large image data sets in high-resolution imaging mass spectrometry.

artículo científico publicado en 2007

Tumor Heterogeneity Underlies Differential Cisplatin Sensitivity in Mouse Models of Small-Cell Lung Cancer

artículo científico publicado en 2019

Whole gel processing procedure for GeLC-MS/MS based proteomics ⬇️

artículo científico publicado el 23 de abril de 2013

Workflow comparison for label-free, quantitative secretome proteomics for cancer biomarker discovery: method evaluation, differential analysis, and verification in serum

artículo científico publicado en 2010

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