Lista de obras -

A comprehensive rat transcriptome built from large scale RNA-seq-based annotation

artículo científico publicado en 2020

A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages

artículo científico publicado en 2014

An investigation of biomarkers derived from legacy microarray data for their utility in the RNA-seq era

artículo científico publicado en 2014

Applying network analysis and Nebula (neighbor-edges based and unbiased leverage algorithm) to ToxCast data

artículo científico publicado en 2016

ArrayTrack--supporting toxicogenomic research at the U.S. Food and Drug Administration National Center for Toxicological Research

artículo científico publicado en 2003

Assessing QSAR Limitations - A Regulatory Perspective

Assessing batch effects of genotype calling algorithm BRLMM for the Affymetrix GeneChip Human Mapping 500 K array set using 270 HapMap samples

artículo científico publicado en 2008

Assessing reproducibility of inherited variants detected with short-read whole genome sequencing

artículo científico publicado en 2022

Assessing technical performance in differential gene expression experiments with external spike-in RNA control ratio mixtures

artículo científico publicado en 2014

Assessment of prediction confidence and domain extrapolation of two structure-activity relationship models for predicting estrogen receptor binding activity

artículo científico publicado en 2004

CERAPP: Collaborative Estrogen Receptor Activity Prediction Project

artículo científico publicado en 2016

CYP2A6, CYP2B6 and CYP2E1 copy number variation in five ethnic groups

artículo científico publicado el 1 de abril de 2013

CYP2D6 genotype predicts tamoxifen side effects but not cancer-free or survival benefits in postmenopausal ER+ and/or PgR+ breast cancers

artículo científico publicado el 1 de abril de 2013

CoMPARA: Collaborative Modeling Project for Androgen Receptor Activity

scientific article published on 07 February 2020

Comparing genetic variants detected in the 1000 genomes project with SNPs determined by the International HapMap Consortium

artículo científico publicado en 2015

Comparing next-generation sequencing and microarray technologies in a toxicological study of the effects of aristolochic acid on rat kidneys

artículo científico publicado en 2011

Comparison of RNA-seq and microarray-based models for clinical endpoint prediction

artículo científico publicado en 2015

Competitive molecular docking approach for predicting estrogen receptor subtype α agonists and antagonists

artículo científico publicado en 2014

Correction to: Similarities and differences between variants called with human reference genome HG19 or HG38

scholarly article published in BMC Bioinformatics

Correlation analysis of external RNA controls reveals its utility for assessment of microarray assay

artículo científico publicado en 2008

Critical role of bioinformatics in translating huge amounts of next-generation sequencing data into personalized medicine

artículo científico publicado en 2013

Cross-oncopanel study reveals high sensitivity and accuracy with overall analytical performance depending on genomic regions

artículo científico publicado en 2021

Cross-platform comparability of microarray technology: intra-platform consistency and appropriate data analysis procedures are essential

artículo científico publicado en 2005

Cross-platform ultradeep transcriptomic profiling of human reference RNA samples by RNA-Seq

artículo científico publicado en 2014

Development and Validation of Decision Forest Model for Estrogen Receptor Binding Prediction of Chemicals Using Large Data Sets

artículo científico publicado en 2015

Development of a Nicotinic Acetylcholine Receptor nAChR α7 Binding Activity Prediction Model

scientific article published on 24 March 2020

Development of public toxicogenomics software for microarray data management and analysis

artículo científico publicado en 2004

Establishing community reference samples, data and call sets for benchmarking cancer mutation detection using whole-genome sequencing

artículo científico publicado en 2021

Estimating relative noise to signal in DNA microarray data ⬇️

artículo científico publicado el 1 de enero de 2013

Estrogenic activity data extraction and in silico prediction show the endocrine disruption potential of bisphenol A replacement compounds

artículo científico publicado en 2015

Evaluating variations of genotype calling: a potential source of spurious associations in genome-wide association studies

artículo científico publicado en 2010

Evaluation of external RNA controls for the assessment of microarray performance

artículo científico publicado en 2006

Evaluation of gene expression data generated from expired Affymetrix GeneChip® microarrays using MAQC reference RNA samples

artículo científico publicado en 2010

Gaining Confidence on Molecular Classification through Consensus Modeling and Validation

artículo científico publicado en 2006

Identification of Epidemiological Traits by Analysis of SARS−CoV−2 Sequences

artículo científico publicado en 2021

Identification of a nucleotide binding site in HIV-1 integrase ⬇️

artículo científico publicado el 14 de abril de 1998

Linkage disequilibrium characterization of CYP2C and CYP2D genomic regions in European populations

artículo científico publicado el 1 de abril de 2013

Machine Learning Methods for Predicting HLA-Peptide Binding Activity

artículo científico publicado en 2015

Microarray scanner calibration curves: characteristics and implications

artículo científico publicado en 2005

Modeling Chemical Interaction Profiles: I. Spectral Data-Activity Relationship and Structure-Activity Relationship Models for Inhibitors and Non-inhibitors of Cytochrome P450 CYP3A4 and CYP2D6 Isozymes ⬇️

artículo científico publicado el 15 de marzo de 2012

Modeling Chemical Interaction Profiles: II. Molecular Docking, Spectral Data-Activity Relationship, and Structure-Activity Relationship Models for Potent and Weak Inhibitors of Cytochrome P450 CYP3A4 Isozyme ⬇️

artículo científico publicado el 15 de marzo de 2012

Mold(2), molecular descriptors from 2D structures for chemoinformatics and toxicoinformatics

artículo científico publicado en 2008

Molecular biomarkers: a US FDA effort

artículo científico publicado en 2010

Molecular docking to identify associations between drugs and class I human leukocyte antigens for predicting idiosyncratic drug reactions.

artículo científico publicado en 2015

Multiclass Decision Forest--a novel pattern recognition method for multiclass classification in microarray data analysis

artículo científico publicado en 2004

Multiple microRNAs function as self-protective modules in acetaminophen-induced hepatotoxicity in humans

artículo científico publicado en 2017

Next generation sequencing for profiling expression of miRNAs: technical progress and applications in drug development ⬇️

artículo científico publicado el 1 de octubre de 2011

Next-generation sequencing and its applications in molecular diagnostics

artículo científico publicado en 2011

Persistent Organic Pollutants in Food: Contamination Sources, Health Effects and Detection Methods

artículo científico publicado en 2019

Potent Inhibitors of Human Immunodeficiency Virus Type 1 Integrase: Identification of a Novel Four-Point Pharmacophore and Tetracyclines as Novel Inhibitors ⬇️

artículo científico publicado el 1 de diciembre de 1997

Prediction of estrogen receptor binding for 58,000 chemicals using an integrated system of a tree-based model with structural alerts

artículo científico publicado en 2002

QUICK: Quality and Usability Investigation and Control Kit for Mass Spectrometric Data from Detection of Persistent Organic Pollutants

scientific article published on 30 October 2019

Quality control and quality assessment of data from surface-enhanced laser desorption/ionization (SELDI) time-of flight (TOF) mass spectrometry (MS).

artículo científico publicado en 2005

Quantitative Structure-Activity Relationship Models for Predicting Drug-Induced Liver Injury Based on FDA-Approved Drug Labeling Annotation and Using a Large Collection of Drugs ⬇️

artículo científico publicado el 31 de agosto de 2013

Rat α-Fetoprotein Binding Affinities of a Large Set of Structurally Diverse Chemicals Elucidated the Relationships between Structures and Binding Affinities ⬇️

artículo científico publicado el 12 de octubre de 2012

Reproducibility challenges for biomarker detection with uncertain but informative experimental data

artículo científico publicado en 2020

SNPTrackTM: an integrated bioinformatics system for genetic association studies ⬇️

artículo científico publicado el 5 de julio de 2012

Salicylhydrazine-Containing Inhibitors of HIV-1 Integrase: Implication for a Selective Chelation in the Integrase Active Site ⬇️

artículo científico publicado el 13 de agosto de 1998

Sequencing XMET genes to promote genotype-guided risk assessment and precision medicine

artículo científico publicado en 2019

Similarities and differences between variants called with human reference genome HG19 or HG38

Software-Assisted Pattern Recognition of Persistent Organic Pollutants in Contaminated Human and Animal Food

artículo científico publicado en 2021

Studies on abacavir-induced hypersensitivity reaction: a successful example of translation of pharmacogenetics to personalized medicine ⬇️

artículo científico publicado el 8 de febrero de 2013

Study of 202 Natural, Synthetic, and Environmental Chemicals for Binding to the Androgen Receptor ⬇️

artículo científico publicado el 1 de octubre de 2003

Technical reproducibility of genotyping SNP arrays used in genome-wide association studies

artículo científico publicado en 2012

The EDKB: an established knowledge base for endocrine disrupting chemicals

artículo científico publicado en 2010

The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements

artículo científico publicado en 2006

The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models

artículo científico publicado en 2010

The accurate prediction of protein family from amino acid sequence by measuring features of sequence fragments

artículo científico publicado en 2009

The balance of reproducibility, sensitivity, and specificity of lists of differentially expressed genes in microarray studies

artículo científico publicado en 2008

The concordance between RNA-seq and microarray data depends on chemical treatment and transcript abundance

artículo científico publicado en 2014

Toward best practice in cancer mutation detection with whole-genome and whole-exome sequencing

artículo científico publicado en 2021

Transcriptomic profiling of rat liver samples in a comprehensive study design by RNA-Seq

artículo científico publicado en 2014

Two new ArrayTrack libraries for personalized biomedical research ⬇️

artículo científico publicado el 7 de octubre de 2010

Understanding and predicting binding between human leukocyte antigens (HLAs) and peptides by network analysis

artículo científico publicado en 2015

Using decision forest to classify prostate cancer samples on the basis of SELDI-TOF MS data: assessing chance correlation and prediction confidence

artículo científico publicado en 2004

Very Important Pool (VIP) genes--an application for microarray-based molecular signatures

artículo científico publicado en 2008

Voluntary exploratory data submissions to the US FDA and the EMA: experience and impact

artículo científico publicado en 2010

Whole genome and exome sequencing reference datasets from a multi-center and cross-platform benchmark study

publication published on 09 November 2021

Whole genome sequencing of 35 individuals provides insights into the genetic architecture of Korean population

artículo científico publicado en 2014

Lista de obras de

A comprehensive rat transcriptome built from large scale RNA-seq-based annotation

A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages

An investigation of biomarkers derived from legacy microarray data for their utility in the RNA-seq era

Applying network analysis and Nebula (neighbor-edges based and unbiased leverage algorithm) to ToxCast data

ArrayTrack--supporting toxicogenomic research at the U.S. Food and Drug Administration National Center for Toxicological Research

Assessing QSAR Limitations - A Regulatory Perspective

Assessing batch effects of genotype calling algorithm BRLMM for the Affymetrix GeneChip Human Mapping 500 K array set using 270 HapMap samples

Assessing reproducibility of inherited variants detected with short-read whole genome sequencing

Assessing technical performance in differential gene expression experiments with external spike-in RNA control ratio mixtures

Assessment of prediction confidence and domain extrapolation of two structure-activity relationship models for predicting estrogen receptor binding activity

CERAPP: Collaborative Estrogen Receptor Activity Prediction Project

CYP2A6, CYP2B6 and CYP2E1 copy number variation in five ethnic groups

CYP2D6 genotype predicts tamoxifen side effects but not cancer-free or survival benefits in postmenopausal ER+ and/or PgR+ breast cancers

CoMPARA: Collaborative Modeling Project for Androgen Receptor Activity

Comparing genetic variants detected in the 1000 genomes project with SNPs determined by the International HapMap Consortium

Comparing next-generation sequencing and microarray technologies in a toxicological study of the effects of aristolochic acid on rat kidneys

Comparison of RNA-seq and microarray-based models for clinical endpoint prediction

Competitive molecular docking approach for predicting estrogen receptor subtype α agonists and antagonists

Correction to: Similarities and differences between variants called with human reference genome HG19 or HG38

Correlation analysis of external RNA controls reveals its utility for assessment of microarray assay

Critical role of bioinformatics in translating huge amounts of next-generation sequencing data into personalized medicine

Cross-oncopanel study reveals high sensitivity and accuracy with overall analytical performance depending on genomic regions

Cross-platform comparability of microarray technology: intra-platform consistency and appropriate data analysis procedures are essential

Cross-platform ultradeep transcriptomic profiling of human reference RNA samples by RNA-Seq

Development and Validation of Decision Forest Model for Estrogen Receptor Binding Prediction of Chemicals Using Large Data Sets

Development of a Nicotinic Acetylcholine Receptor nAChR α7 Binding Activity Prediction Model

Development of public toxicogenomics software for microarray data management and analysis

Establishing community reference samples, data and call sets for benchmarking cancer mutation detection using whole-genome sequencing

Estimating relative noise to signal in DNA microarray data ⬇️

Estrogenic activity data extraction and in silico prediction show the endocrine disruption potential of bisphenol A replacement compounds

Evaluating variations of genotype calling: a potential source of spurious associations in genome-wide association studies

Evaluation of external RNA controls for the assessment of microarray performance

Evaluation of gene expression data generated from expired Affymetrix GeneChip® microarrays using MAQC reference RNA samples

Gaining Confidence on Molecular Classification through Consensus Modeling and Validation

Identification of Epidemiological Traits by Analysis of SARS−CoV−2 Sequences

Identification of a nucleotide binding site in HIV-1 integrase ⬇️

Linkage disequilibrium characterization of CYP2C and CYP2D genomic regions in European populations

Machine Learning Methods for Predicting HLA-Peptide Binding Activity

Microarray scanner calibration curves: characteristics and implications

Modeling Chemical Interaction Profiles: I. Spectral Data-Activity Relationship and Structure-Activity Relationship Models for Inhibitors and Non-inhibitors of Cytochrome P450 CYP3A4 and CYP2D6 Isozymes ⬇️

Modeling Chemical Interaction Profiles: II. Molecular Docking, Spectral Data-Activity Relationship, and Structure-Activity Relationship Models for Potent and Weak Inhibitors of Cytochrome P450 CYP3A4 Isozyme ⬇️

Mold(2), molecular descriptors from 2D structures for chemoinformatics and toxicoinformatics

Molecular biomarkers: a US FDA effort

Molecular docking to identify associations between drugs and class I human leukocyte antigens for predicting idiosyncratic drug reactions.

Multiclass Decision Forest--a novel pattern recognition method for multiclass classification in microarray data analysis

Multiple microRNAs function as self-protective modules in acetaminophen-induced hepatotoxicity in humans

Next generation sequencing for profiling expression of miRNAs: technical progress and applications in drug development ⬇️

Next-generation sequencing and its applications in molecular diagnostics

Persistent Organic Pollutants in Food: Contamination Sources, Health Effects and Detection Methods

Potent Inhibitors of Human Immunodeficiency Virus Type 1 Integrase: Identification of a Novel Four-Point Pharmacophore and Tetracyclines as Novel Inhibitors ⬇️

Prediction of estrogen receptor binding for 58,000 chemicals using an integrated system of a tree-based model with structural alerts

QUICK: Quality and Usability Investigation and Control Kit for Mass Spectrometric Data from Detection of Persistent Organic Pollutants

Quality control and quality assessment of data from surface-enhanced laser desorption/ionization (SELDI) time-of flight (TOF) mass spectrometry (MS).

Quantitative Structure-Activity Relationship Models for Predicting Drug-Induced Liver Injury Based on FDA-Approved Drug Labeling Annotation and Using a Large Collection of Drugs ⬇️

Rat α-Fetoprotein Binding Affinities of a Large Set of Structurally Diverse Chemicals Elucidated the Relationships between Structures and Binding Affinities ⬇️

Reproducibility challenges for biomarker detection with uncertain but informative experimental data

SNPTrackTM: an integrated bioinformatics system for genetic association studies ⬇️

Salicylhydrazine-Containing Inhibitors of HIV-1 Integrase: Implication for a Selective Chelation in the Integrase Active Site ⬇️

Sequencing XMET genes to promote genotype-guided risk assessment and precision medicine

Similarities and differences between variants called with human reference genome HG19 or HG38

Software-Assisted Pattern Recognition of Persistent Organic Pollutants in Contaminated Human and Animal Food

Studies on abacavir-induced hypersensitivity reaction: a successful example of translation of pharmacogenetics to personalized medicine ⬇️

Study of 202 Natural, Synthetic, and Environmental Chemicals for Binding to the Androgen Receptor ⬇️

Technical reproducibility of genotyping SNP arrays used in genome-wide association studies

The EDKB: an established knowledge base for endocrine disrupting chemicals

The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements

The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models

The accurate prediction of protein family from amino acid sequence by measuring features of sequence fragments

The balance of reproducibility, sensitivity, and specificity of lists of differentially expressed genes in microarray studies

The concordance between RNA-seq and microarray data depends on chemical treatment and transcript abundance

Toward best practice in cancer mutation detection with whole-genome and whole-exome sequencing

Transcriptomic profiling of rat liver samples in a comprehensive study design by RNA-Seq

Two new ArrayTrack libraries for personalized biomedical research ⬇️

Understanding and predicting binding between human leukocyte antigens (HLAs) and peptides by network analysis

Using decision forest to classify prostate cancer samples on the basis of SELDI-TOF MS data: assessing chance correlation and prediction confidence

Very Important Pool (VIP) genes--an application for microarray-based molecular signatures

Voluntary exploratory data submissions to the US FDA and the EMA: experience and impact

Whole genome and exome sequencing reference datasets from a multi-center and cross-platform benchmark study

Whole genome sequencing of 35 individuals provides insights into the genetic architecture of Korean population