Lista de obras - Hadi Al-Hasani - Dominio Público Uruguay

14-3-3 binding to the IGF-1 receptor is mediated by serine autophosphorylation

artículo científico publicado en 2002

A collective diabetes cross in combination with a computational framework to dissect the genetics of human obesity and Type 2 diabetes

artículo científico publicado en 2018

A dual role of the N-terminal FQQI motif in GLUT4 trafficking

artículo científico publicado en 2009

A meta-analysis of QTL for diabetes-related traits in rodents.

artículo científico publicado en 2008

AKT and AMPK regulate TBC1D1 through phosphorylation and its interaction with the cytosolic tail of insulin-regulated aminopeptidase IRAP

scientific article published in Journal of Biological Chemistry

AKT/AMPK-mediated phosphorylation of TBC1D4 disrupts the interaction with insulin-regulated aminopeptidase

artículo científico publicado en 2021

AMPK and TBC1D1 Regulate Muscle Glucose Uptake After - But Not During - Exercise and Contraction

scientific article published on 22 April 2019

Activin A impairs insulin action in cardiomyocytes via up-regulation of miR-143

artículo científico publicado en 2013

Activity, phosphorylation state and subcellular distribution of GLUT4-targeted Akt2 in rat adipose cells

artículo científico publicado en 2003

Altered GLUT4 trafficking in adipocytes in the absence of the GTPase Arfrp1.

artículo científico publicado en 2010

Analysis of Genes Involved in Body Weight Regulation by Targeted Re-Sequencing

artículo científico publicado en 2016

Association of the FTO rs9939609 single nucleotide polymorphism with C-reactive protein levels

artículo científico publicado en 2008

Biomarker discovery and redundancy reduction towards classification using a multi-factorial MALDI-TOF MS T2DM mouse model dataset ⬇️

artículo científico publicado en 2011

CDH13 abundance interferes with adipocyte differentiation and is a novel biomarker for adipose tissue health

artículo científico publicado en 2018

Cohort profile: the German Diabetes Study (GDS).

artículo científico publicado en 2016

Conventional knockout of Tbc1d1 in mice impairs insulin- and AICAR-stimulated glucose uptake in skeletal muscle

artículo científico publicado en 2013

Critical illness myopathy and GLUT4: significance of insulin and muscle contraction

artículo científico publicado en 2012

Cytokine response of primary human myotubes in an in vitro exercise model

artículo científico publicado en 2013

Deletion of both Rab-GTPase-activating proteins TBC14KO and TBC1D4 in mice eliminates insulin- and AICAR-stimulated glucose transport. Diabetes 2015;64:746-759

artículo científico publicado en 2015

Deletion of the RabGAP TBC1D1 Leads to Enhanced Insulin Secretion and Fatty Acid Oxidation in Islets From Male Mice

artículo científico publicado en 2018

Demonstration of differential quantitative requirements for NSF among multiple vesicle fusion pathways of GLUT4 using a dominant-negative ATPase-deficient NSF.

artículo científico publicado en 2005

Endocytosis of the Glucose Transporter GLUT4 Is Mediated by the GTPase Dynamin ⬇️

artículo científico publicado el 10 de julio de 1998

Endocytosis of the glucose transporter GLUT8 is mediated by interaction of a dileucine motif with the beta2-adaptin subunit of the AP-2 adaptor complex.

artículo científico publicado en 2006

FGF21 regulates insulin sensitivity following long-term chronic stress.

artículo científico publicado en 2018

Fine mapping of mouse QTLs for fatness using SNP data.

artículo científico publicado en 2007

Ghrelin-induced food intake and adiposity depend on central mTORC1/S6K1 signaling

artículo científico publicado en 2013

Glucose transporters in adipose tissue, liver, and skeletal muscle in metabolic health and disease

artículo científico publicado en 2020

Histone deacetylase 5 regulates Interleukin 6 secretion and insulin action in skeletal muscle

scientific article published on 06 August 2020

Identification and characterization of p49/STRAP as a novel GLUT4-binding protein

artículo científico publicado en 2006

Immunity-related GTPase induces lipophagy to prevent excess hepatic lipid accumulation

artículo científico publicado en 2020

Innate Immune Signals Induce Anterograde Endosome Transport Promoting MHC Class I Cross-Presentation

scientific article published on 01 September 2018

Insulin stimulates fusion, but not tethering, of GLUT4 vesicles in skeletal muscle of HA-GLUT4-GFP transgenic mice

artículo científico publicado en 2012

Intestinal dehydroascorbic acid (DHA) transport mediated by the facilitative sugar transporters, GLUT2 and GLUT8.

artículo científico publicado en 2013

Isoform-specific AMPK association with TBC1D1 is reduced by a mutation associated with severe obesity

artículo científico publicado en 2018

Lipidomics-Reshaping the Analysis and Perception of Type 2 Diabetes

artículo científico publicado en 2016

Meta-analysis approach identifies candidate genes and associated molecular networks for type-2 diabetes mellitus

artículo científico publicado en 2008

Molecular links between Obesity and Diabetes: “Diabesity”

artículo científico publicado en 2015

Nutrition-/diet-induced changes in gene expression in white adipose tissue

artículo científico publicado en 2005

Opposing effects of reduced kidney mass on liver and skeletal muscle insulin sensitivity in obese mice

artículo científico publicado en 2014

Over-expression of PRAS40 enhances insulin sensitivity in skeletal muscle.

artículo científico publicado en 2014

PPINGUIN: Peptide Profiling Guided Identification of Proteins improves quantitation of iTRAQ ratios

artículo científico publicado en 2012

Physiological Disturbance in Fatty Liver Energy Metabolism Converges on IGFBP2 Abundance and Regulation in Mice and Men

artículo científico publicado en 2020

Positional cloning of zinc finger domain transcription factor Zfp69, a candidate gene for obesity-associated diabetes contributed by mouse locus Nidd/SJL

artículo científico publicado en 2009

Pronounced reduction of cutaneous Langerhans cell density in recently diagnosed type 2 diabetes.

artículo científico publicado en 2013

Rab-GAP TBC1D4 (AS160) is dispensable for the renal control of sodium and water homeostasis but regulates GLUT4 in mouse kidney

artículo científico publicado en 2015

Rab28 is a TBC1D1/TBC1D4 substrate involved in GLUT4 trafficking

artículo científico publicado en 2016

RabGAPs in skeletal muscle function and exercise

artículo científico publicado en 2020

Re-patterning of skeletal muscle energy metabolism by fat storage-inducing transmembrane protein 2.

artículo científico publicado en 2011

Regulation of RabGAPs involved in insulin action

artículo científico publicado en 2018

Role of Patatin-Like Phospholipase Domain-Containing 3 Gene for Hepatic Lipid Content and Insulin Resistance in Diabetes

scientific article published on 19 June 2020

Roles of the N- and C-termini of GLUT4 in endocytosis

artículo científico publicado en 2002

Specific Metabolic Profiles and Their Relationship to Insulin Resistance in Recent-Onset Type 1 and Type 2 Diabetes.

artículo científico publicado en 2016

TBC1D1 interacting proteins, VPS13A and VPS13C, regulate GLUT4 homeostasis in C2C12 myotubes

artículo científico publicado en 2020

TBC1D4 Is Necessary for Enhancing Muscle Insulin Sensitivity in Response to AICAR and Contraction

artículo científico publicado en 2019

Targeted disruption of Slc2a8 (GLUT8) reduces motility and mitochondrial potential of spermatozoa

artículo científico publicado en 2008

Tbc1d1 mutation in lean mouse strain confers leanness and protects from diet-induced obesity

artículo científico publicado en 2008

The Rab-GTPase-activating protein TBC1D1 regulates skeletal muscle glucose metabolism

artículo científico publicado en 2012

The RabGAPs TBC1D1 and TBC1D4 Control Uptake of Long-Chain Fatty Acids Into Skeletal Muscle Via Fatty Acid Transporter SLC27A4/FATP4

scientific article published on 31 August 2020

The elongated first fibronectin type III domain of collagen XIV is an inducer of quiescence and differentiation in fibroblasts and preadipocytes

artículo científico publicado en 2005

Tuning in to the rhythm of clock genes in skeletal muscle

artículo científico publicado en 2013

Two Novel Candidate Genes for Insulin Secretion Identified by Comparative Genomics of Multiple Backcross Mouse Populations

article

Two birds with one stone: novel glucokinase activator stimulates glucose-induced pancreatic insulin secretion and augments hepatic glucose metabolism

artículo científico publicado en 2003

Use of multiple metabolic and genetic markers to improve the prediction of type 2 diabetes: the EPIC-Potsdam Study

artículo científico publicado en 2009

Variants in Genes Controlling Oxidative Metabolism Contribute to Lower Hepatic ATP Independent of Liver Fat Content in Type 1 Diabetes

artículo científico publicado en 2016

Whole-exome sequencing identifies mutations of TBC1D1 encoding a Rab-GTPase-activating protein in patients with congenital anomalies of the kidneys and urinary tract (CAKUT).

artículo científico publicado en 2015

“Deletion of both Rab-GTPase–activating proteins TBC1D1 and TBC1D4 in mice eliminates insulin- and AICAR-stimulated glucose transport [corrected].

artículo científico publicado en 2014

Lista de obras de Hadi Al-Hasani

14-3-3 binding to the IGF-1 receptor is mediated by serine autophosphorylation

A collective diabetes cross in combination with a computational framework to dissect the genetics of human obesity and Type 2 diabetes

A dual role of the N-terminal FQQI motif in GLUT4 trafficking

A meta-analysis of QTL for diabetes-related traits in rodents.

AKT and AMPK regulate TBC1D1 through phosphorylation and its interaction with the cytosolic tail of insulin-regulated aminopeptidase IRAP

AKT/AMPK-mediated phosphorylation of TBC1D4 disrupts the interaction with insulin-regulated aminopeptidase

AMPK and TBC1D1 Regulate Muscle Glucose Uptake After - But Not During - Exercise and Contraction

Activin A impairs insulin action in cardiomyocytes via up-regulation of miR-143

Activity, phosphorylation state and subcellular distribution of GLUT4-targeted Akt2 in rat adipose cells

Altered GLUT4 trafficking in adipocytes in the absence of the GTPase Arfrp1.

Analysis of Genes Involved in Body Weight Regulation by Targeted Re-Sequencing

Association of the FTO rs9939609 single nucleotide polymorphism with C-reactive protein levels

Biomarker discovery and redundancy reduction towards classification using a multi-factorial MALDI-TOF MS T2DM mouse model dataset ⬇️

CDH13 abundance interferes with adipocyte differentiation and is a novel biomarker for adipose tissue health

Cohort profile: the German Diabetes Study (GDS).

Conventional knockout of Tbc1d1 in mice impairs insulin- and AICAR-stimulated glucose uptake in skeletal muscle

Critical illness myopathy and GLUT4: significance of insulin and muscle contraction

Cytokine response of primary human myotubes in an in vitro exercise model

Deletion of both Rab-GTPase-activating proteins TBC14KO and TBC1D4 in mice eliminates insulin- and AICAR-stimulated glucose transport. Diabetes 2015;64:746-759

Deletion of the RabGAP TBC1D1 Leads to Enhanced Insulin Secretion and Fatty Acid Oxidation in Islets From Male Mice

Demonstration of differential quantitative requirements for NSF among multiple vesicle fusion pathways of GLUT4 using a dominant-negative ATPase-deficient NSF.

Endocytosis of the Glucose Transporter GLUT4 Is Mediated by the GTPase Dynamin ⬇️

Endocytosis of the glucose transporter GLUT8 is mediated by interaction of a dileucine motif with the beta2-adaptin subunit of the AP-2 adaptor complex.

FGF21 regulates insulin sensitivity following long-term chronic stress.

Fine mapping of mouse QTLs for fatness using SNP data.

Ghrelin-induced food intake and adiposity depend on central mTORC1/S6K1 signaling

Glucose transporters in adipose tissue, liver, and skeletal muscle in metabolic health and disease

Histone deacetylase 5 regulates Interleukin 6 secretion and insulin action in skeletal muscle

Identification and characterization of p49/STRAP as a novel GLUT4-binding protein

Immunity-related GTPase induces lipophagy to prevent excess hepatic lipid accumulation

Innate Immune Signals Induce Anterograde Endosome Transport Promoting MHC Class I Cross-Presentation

Insulin stimulates fusion, but not tethering, of GLUT4 vesicles in skeletal muscle of HA-GLUT4-GFP transgenic mice

Intestinal dehydroascorbic acid (DHA) transport mediated by the facilitative sugar transporters, GLUT2 and GLUT8.

Isoform-specific AMPK association with TBC1D1 is reduced by a mutation associated with severe obesity

Lipidomics-Reshaping the Analysis and Perception of Type 2 Diabetes

Meta-analysis approach identifies candidate genes and associated molecular networks for type-2 diabetes mellitus

Molecular links between Obesity and Diabetes: “Diabesity”

Nutrition-/diet-induced changes in gene expression in white adipose tissue

Opposing effects of reduced kidney mass on liver and skeletal muscle insulin sensitivity in obese mice

Over-expression of PRAS40 enhances insulin sensitivity in skeletal muscle.

PPINGUIN: Peptide Profiling Guided Identification of Proteins improves quantitation of iTRAQ ratios

Physiological Disturbance in Fatty Liver Energy Metabolism Converges on IGFBP2 Abundance and Regulation in Mice and Men

Positional cloning of zinc finger domain transcription factor Zfp69, a candidate gene for obesity-associated diabetes contributed by mouse locus Nidd/SJL

Pronounced reduction of cutaneous Langerhans cell density in recently diagnosed type 2 diabetes.

Rab-GAP TBC1D4 (AS160) is dispensable for the renal control of sodium and water homeostasis but regulates GLUT4 in mouse kidney

Rab28 is a TBC1D1/TBC1D4 substrate involved in GLUT4 trafficking

RabGAPs in skeletal muscle function and exercise

Re-patterning of skeletal muscle energy metabolism by fat storage-inducing transmembrane protein 2.

Regulation of RabGAPs involved in insulin action

Role of Patatin-Like Phospholipase Domain-Containing 3 Gene for Hepatic Lipid Content and Insulin Resistance in Diabetes

Roles of the N- and C-termini of GLUT4 in endocytosis

Specific Metabolic Profiles and Their Relationship to Insulin Resistance in Recent-Onset Type 1 and Type 2 Diabetes.

TBC1D1 interacting proteins, VPS13A and VPS13C, regulate GLUT4 homeostasis in C2C12 myotubes

TBC1D4 Is Necessary for Enhancing Muscle Insulin Sensitivity in Response to AICAR and Contraction

Targeted disruption of Slc2a8 (GLUT8) reduces motility and mitochondrial potential of spermatozoa

Tbc1d1 mutation in lean mouse strain confers leanness and protects from diet-induced obesity

The Rab-GTPase-activating protein TBC1D1 regulates skeletal muscle glucose metabolism

The RabGAPs TBC1D1 and TBC1D4 Control Uptake of Long-Chain Fatty Acids Into Skeletal Muscle Via Fatty Acid Transporter SLC27A4/FATP4

The elongated first fibronectin type III domain of collagen XIV is an inducer of quiescence and differentiation in fibroblasts and preadipocytes

Tuning in to the rhythm of clock genes in skeletal muscle

Two Novel Candidate Genes for Insulin Secretion Identified by Comparative Genomics of Multiple Backcross Mouse Populations

Two birds with one stone: novel glucokinase activator stimulates glucose-induced pancreatic insulin secretion and augments hepatic glucose metabolism

Use of multiple metabolic and genetic markers to improve the prediction of type 2 diabetes: the EPIC-Potsdam Study

Variants in Genes Controlling Oxidative Metabolism Contribute to Lower Hepatic ATP Independent of Liver Fat Content in Type 1 Diabetes

Whole-exome sequencing identifies mutations of TBC1D1 encoding a Rab-GTPase-activating protein in patients with congenital anomalies of the kidneys and urinary tract (CAKUT).

“Deletion of both Rab-GTPase–activating proteins TBC1D1 and TBC1D4 in mice eliminates insulin- and AICAR-stimulated glucose transport [corrected].