Lista de obras -

A collective diabetes cross in combination with a computational framework to dissect the genetics of human obesity and Type 2 diabetes

artículo científico publicado en 2018

AKT and AMPK regulate TBC1D1 through phosphorylation and its interaction with the cytosolic tail of insulin-regulated aminopeptidase IRAP

scientific article published in Journal of Biological Chemistry

AKT/AMPK-mediated phosphorylation of TBC1D4 disrupts the interaction with insulin-regulated aminopeptidase

artículo científico publicado en 2021

AMPK and TBC1D1 Regulate Muscle Glucose Uptake After - But Not During - Exercise and Contraction

scientific article published on 22 April 2019

An interval of the obesity QTL Nob3.38 within a QTL hotspot on chromosome 1 modulates behavioral phenotypes

artículo científico publicado en 2013

Biomarker discovery and redundancy reduction towards classification using a multi-factorial MALDI-TOF MS T2DM mouse model dataset ⬇️

artículo científico publicado en 2011

Conventional knockout of Tbc1d1 in mice impairs insulin- and AICAR-stimulated glucose uptake in skeletal muscle

artículo científico publicado en 2013

Critical illness myopathy and GLUT4: significance of insulin and muscle contraction

artículo científico publicado en 2012

Deletion of both Rab-GTPase-activating proteins TBC14KO and TBC1D4 in mice eliminates insulin- and AICAR-stimulated glucose transport. Diabetes 2015;64:746-759

artículo científico publicado en 2015

Deletion of the RabGAP TBC1D1 Leads to Enhanced Insulin Secretion and Fatty Acid Oxidation in Islets From Male Mice

artículo científico publicado en 2018

FGF21 regulates insulin sensitivity following long-term chronic stress.

artículo científico publicado en 2018

Glucose transporters in adipose tissue, liver, and skeletal muscle in metabolic health and disease

artículo científico publicado en 2020

Histone deacetylase 5 regulates Interleukin 6 secretion and insulin action in skeletal muscle

scientific article published on 06 August 2020

Hypoxia in Combination With Muscle Contraction Improves Insulin Action and Glucose Metabolism in Human Skeletal Muscle via the HIF-1α Pathway

artículo científico publicado en 2017

Immunity-related GTPase induces lipophagy to prevent excess hepatic lipid accumulation

artículo científico publicado en 2020

Innate Immune Signals Induce Anterograde Endosome Transport Promoting MHC Class I Cross-Presentation

scientific article published on 01 September 2018

Insulin stimulates fusion, but not tethering, of GLUT4 vesicles in skeletal muscle of HA-GLUT4-GFP transgenic mice

artículo científico publicado en 2012

Isoform-specific AMPK association with TBC1D1 is reduced by a mutation associated with severe obesity

artículo científico publicado en 2018

Molecular links between Obesity and Diabetes: “Diabesity”

artículo científico publicado en 2015

Over-expression of PRAS40 enhances insulin sensitivity in skeletal muscle.

artículo científico publicado en 2014

PPINGUIN: Peptide Profiling Guided Identification of Proteins improves quantitation of iTRAQ ratios

artículo científico publicado en 2012

Rab28 is a TBC1D1/TBC1D4 substrate involved in GLUT4 trafficking

artículo científico publicado en 2016

RabGAPs in skeletal muscle function and exercise

artículo científico publicado en 2020

Re-patterning of skeletal muscle energy metabolism by fat storage-inducing transmembrane protein 2.

artículo científico publicado en 2011

Regulation of RabGAPs involved in insulin action

artículo científico publicado en 2018

TBC1D1 interacting proteins, VPS13A and VPS13C, regulate GLUT4 homeostasis in C2C12 myotubes

artículo científico publicado en 2020

TBC1D4 Is Necessary for Enhancing Muscle Insulin Sensitivity in Response to AICAR and Contraction

artículo científico publicado en 2019

Tbc1d1 mutation in lean mouse strain confers leanness and protects from diet-induced obesity

artículo científico publicado en 2008

The ARF-like GTPase ARFRP1 is essential for lipid droplet growth and is involved in the regulation of lipolysis

artículo científico publicado en 2009

The Rab-GTPase-activating protein TBC1D1 regulates skeletal muscle glucose metabolism

artículo científico publicado en 2012

The RabGAPs TBC1D1 and TBC1D4 Control Uptake of Long-Chain Fatty Acids Into Skeletal Muscle Via Fatty Acid Transporter SLC27A4/FATP4

scientific article published on 31 August 2020

Tuning in to the rhythm of clock genes in skeletal muscle

artículo científico publicado en 2013

Two Novel Candidate Genes for Insulin Secretion Identified by Comparative Genomics of Multiple Backcross Mouse Populations

article

Whole-exome sequencing identifies mutations of TBC1D1 encoding a Rab-GTPase-activating protein in patients with congenital anomalies of the kidneys and urinary tract (CAKUT).

artículo científico publicado en 2015

“Deletion of both Rab-GTPase–activating proteins TBC1D1 and TBC1D4 in mice eliminates insulin- and AICAR-stimulated glucose transport [corrected].

artículo científico publicado en 2014

Lista de obras de

A collective diabetes cross in combination with a computational framework to dissect the genetics of human obesity and Type 2 diabetes

AKT and AMPK regulate TBC1D1 through phosphorylation and its interaction with the cytosolic tail of insulin-regulated aminopeptidase IRAP

AKT/AMPK-mediated phosphorylation of TBC1D4 disrupts the interaction with insulin-regulated aminopeptidase

AMPK and TBC1D1 Regulate Muscle Glucose Uptake After - But Not During - Exercise and Contraction

An interval of the obesity QTL Nob3.38 within a QTL hotspot on chromosome 1 modulates behavioral phenotypes

Biomarker discovery and redundancy reduction towards classification using a multi-factorial MALDI-TOF MS T2DM mouse model dataset ⬇️

Conventional knockout of Tbc1d1 in mice impairs insulin- and AICAR-stimulated glucose uptake in skeletal muscle

Critical illness myopathy and GLUT4: significance of insulin and muscle contraction

Deletion of both Rab-GTPase-activating proteins TBC14KO and TBC1D4 in mice eliminates insulin- and AICAR-stimulated glucose transport. Diabetes 2015;64:746-759

Deletion of the RabGAP TBC1D1 Leads to Enhanced Insulin Secretion and Fatty Acid Oxidation in Islets From Male Mice

FGF21 regulates insulin sensitivity following long-term chronic stress.

Glucose transporters in adipose tissue, liver, and skeletal muscle in metabolic health and disease

Histone deacetylase 5 regulates Interleukin 6 secretion and insulin action in skeletal muscle

Hypoxia in Combination With Muscle Contraction Improves Insulin Action and Glucose Metabolism in Human Skeletal Muscle via the HIF-1α Pathway

Immunity-related GTPase induces lipophagy to prevent excess hepatic lipid accumulation

Innate Immune Signals Induce Anterograde Endosome Transport Promoting MHC Class I Cross-Presentation

Insulin stimulates fusion, but not tethering, of GLUT4 vesicles in skeletal muscle of HA-GLUT4-GFP transgenic mice

Isoform-specific AMPK association with TBC1D1 is reduced by a mutation associated with severe obesity

Molecular links between Obesity and Diabetes: “Diabesity”

Over-expression of PRAS40 enhances insulin sensitivity in skeletal muscle.

PPINGUIN: Peptide Profiling Guided Identification of Proteins improves quantitation of iTRAQ ratios

Rab28 is a TBC1D1/TBC1D4 substrate involved in GLUT4 trafficking

RabGAPs in skeletal muscle function and exercise

Re-patterning of skeletal muscle energy metabolism by fat storage-inducing transmembrane protein 2.

Regulation of RabGAPs involved in insulin action

TBC1D1 interacting proteins, VPS13A and VPS13C, regulate GLUT4 homeostasis in C2C12 myotubes

TBC1D4 Is Necessary for Enhancing Muscle Insulin Sensitivity in Response to AICAR and Contraction

Tbc1d1 mutation in lean mouse strain confers leanness and protects from diet-induced obesity

The ARF-like GTPase ARFRP1 is essential for lipid droplet growth and is involved in the regulation of lipolysis

The Rab-GTPase-activating protein TBC1D1 regulates skeletal muscle glucose metabolism

The RabGAPs TBC1D1 and TBC1D4 Control Uptake of Long-Chain Fatty Acids Into Skeletal Muscle Via Fatty Acid Transporter SLC27A4/FATP4

Tuning in to the rhythm of clock genes in skeletal muscle

Two Novel Candidate Genes for Insulin Secretion Identified by Comparative Genomics of Multiple Backcross Mouse Populations

Whole-exome sequencing identifies mutations of TBC1D1 encoding a Rab-GTPase-activating protein in patients with congenital anomalies of the kidneys and urinary tract (CAKUT).

“Deletion of both Rab-GTPase–activating proteins TBC1D1 and TBC1D4 in mice eliminates insulin- and AICAR-stimulated glucose transport [corrected].