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Antibody-Drug Conjugates: The Last Decade

artículo científico publicado en 2020

Characterization of the N-terminal heterogeneities of monoclonal antibodies using in-gel charge derivatization of α-amines and LC-MS/MS.

artículo científico publicado en 2015

Characterization of therapeutic antibodies and related products.

artículo científico

Comprehensive study on the effects of sodium and potassium additives in size exclusion chromatographic separations of protein biopharmaceuticals

artículo científico publicado en 2016

Coupling non-denaturing chromatography to mass spectrometry for the characterization of monoclonal antibodies and related products

artículo científico publicado en 2020

Current possibilities of liquid chromatography for the characterization of antibody-drug conjugates

artículo científico publicado en 2017

Cutting-edge mass spectrometry characterization of originator, biosimilar and biobetter antibodies

artículo científico publicado en 2015

Cutting-edge mass spectrometry methods for the multi-level structural characterization of antibody-drug conjugates.

artículo científico publicado en 2015

Glycosylation of biosimilars: Recent advances in analytical characterization and clinical implications

scientific article published on 22 August 2019

High-resolution separation of monoclonal antibodies mixtures and their charge variants by an alternative and generic CZE method

scientific article published on 04 June 2018

Hydrophobic interaction chromatography for the characterization of monoclonal antibodies and related products

artículo científico publicado en 2016

Impact of organic modifier and temperature on protein denaturation in hydrophobic interaction chromatography

artículo científico publicado en 2016

Innovative native MS methodologies for antibody drug conjugate characterization: High resolution native MS and IM-MS for average DAR and DAR distribution assessment.

artículo científico publicado en 2014

Interlaboratory Study for Characterizing Monoclonal Antibodies by Top-Down and Middle-Down Mass Spectrometry

artículo científico publicado en 2020

Ion-exchange chromatography for the characterization of biopharmaceuticals

artículo científico

Macro- and Micro-Heterogeneity of Natural and Recombinant IgG Antibodies

artículo científico publicado en 2019

Native mass spectrometry and ion mobility characterization of trastuzumab emtansine, a lysine-linked antibody drug conjugate

artículo científico publicado en 2015

Optimized Sample Preparation and Data Processing of Data-Independent Acquisition Methods for the Robust Quantification of Trace-Level Host Cell Protein Impurities in Antibody Drug Products

artículo científico publicado en 2020

Potential of hydrophilic interaction chromatography for the analytical characterization of protein biopharmaceuticals

artículo científico publicado en 2016

Proof of Concept To Achieve Infinite Selectivity for the Chromatographic Separation of Therapeutic Proteins

artículo científico publicado en 2019

Theory and practice of size exclusion chromatography for the analysis of protein aggregates

artículo científico publicado en 2014

Time resolved native ion-mobility mass spectrometry to monitor dynamics of IgG4 Fab arm exchange and "bispecific" monoclonal antibody formation

artículo científico publicado en 2013

Unraveling the mysteries of modern size exclusion chromatography - the way to achieve confident characterization of therapeutic proteins

artículo científico publicado en 2018

Use of Ultra-short Columns for Therapeutic Protein Separations, Part 2: Designing the Optimal Column Dimension for Reversed-Phase Liquid Chromatography

artículo científico publicado en 2020

Use of Ultrashort Columns for Therapeutic Protein Separations. Part 1: Theoretical Considerations and Proof of Concept

artículo científico publicado en 2020