Lista de obras -

A NF54 Reporter Line Expressing mCherry-Luciferase in Gametocytes, Sporozoites, and Liver-Stages

artículo científico publicado en 2019

A Plasmodium falciparum screening assay for anti-gametocyte drugs based on parasite lactate dehydrogenase detection

artículo científico publicado en 2013

A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria

artículo científico publicado en 2015

A new P. falciparum gametocyte drug screening assay based on pLDH detection.

artículo científico publicado en 2012

A novel multiple-stage antimalarial agent that inhibits protein synthesis

artículo científico publicado en 2015

A potent series targeting the malarial cGMP-dependent protein kinase clears infection and blocks transmission.

artículo científico publicado en 2017

A scalable assessment of Plasmodium falciparum transmission in the standard membrane-feeding assay, using transgenic parasites expressing green fluorescent protein-luciferase

artículo científico publicado en 2014

A semi-automated luminescence based standard membrane feeding assay identifies novel small molecules that inhibit transmission of malaria parasites by mosquitoes

artículo científico publicado en 2015

A simple and predictive phenotypic High Content Imaging assay for Plasmodium falciparum mature gametocytes to identify malaria transmission blocking compounds

artículo científico publicado en 2015

An inter-laboratory comparison of standard membrane-feeding assays for evaluation of malaria transmission-blocking vaccines

artículo científico publicado en 2016

Analysis of a Multi-component Multi-stage Malaria Vaccine Candidate--Tackling the Cocktail Challenge

artículo científico publicado en 2015

Analysis of the dose-dependent stage-specific in vitro efficacy of a multi-stage malaria vaccine candidate cocktail

artículo científico publicado en 2016

Antimalarial agents against both sexual and asexual parasites stages: structure-activity relationships and biological studies of the Malaria Box compound 1-[5-(4-bromo-2-chlorophenyl)furan-2-yl]-N-[(piperidin-4-yl)methyl]methanamine (MMV019918) and a

scholarly article by Alessandra Vallone et al published 25 April 2018 in European Journal of Medicinal Chemistry

Antimalarial efficacy of MMV390048, an inhibitor of Plasmodium phosphatidylinositol 4-kinase.

artículo científico publicado en 2017

Antimalarial pantothenamide metabolites target acetyl-coenzyme A biosynthesis in Plasmodium falciparum

artículo científico publicado en 2019

Bioassay development

article

Breast cancer oestrogen independence mediated by BCAR1 or BCAR3 genes is transmitted through mechanisms distinct from the oestrogen receptor signalling pathway or the epidermal growth factor receptor signalling pathway

artículo científico publicado en 2004

Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose-Efficacy Modeling

artículo científico publicado en 2016

Comprehensive microarray analysis of bone morphogenetic protein 2-induced osteoblast differentiation resulting in the identification of novel markers for bone development

artículo científico publicado en 2002

Corrigendum: A novel multiple-stage antimalarial agent that inhibits protein synthesis

artículo científico publicado en 2016

DNA methylation restricts spontaneous multi-lineage differentiation of mesenchymal progenitor cells, but is stable during growth factor-induced terminal differentiation ⬇️

artículo científico publicado el 28 de enero de 2011

Delineation of amplification, hybridization and location effects in microarray data yields better-quality normalization

artículo científico publicado en 2010

Diversity-oriented synthesis yields novel multistage antimalarial inhibitors

artículo científico publicado en 2016

Effect of chordin-like 1 on MC3T3-E1 and human mesenchymal stem cells

artículo científico publicado en 2010

Epigenetics: DNA demethylation promotes skeletal myotube maturation.

artículo científico publicado en 2011

Functional antibodies against sporozoites are associated with a longer time to qPCR-detected infection among schoolchildren in Burkina Faso

artículo científico publicado en 2018

Gene array analysis of bone morphogenetic protein type I receptor-induced osteoblast differentiation.

artículo científico publicado en 2003

High-throughput assay for the identification of compounds regulating osteogenic differentiation of human mesenchymal stromal cells

artículo científico publicado en 2011

Identification of novel bacterial M.SssI DNA methyltransferase inhibitors.

artículo científico publicado en 2012

Identification of novel regulators associated with early-phase osteoblast differentiation

artículo científico publicado en 2004

MicroRNA miR-378 promotes BMP2-induced osteogenic differentiation of mesenchymal progenitor cells

scientific article published on 27 January 2014

Microarray analysis on Runx2-deficient mouse embryos reveals novel Runx2 functions and target genes during intramembranous and endochondral bone formation

artículo científico

Microarray analysis reveals expression regulation of Wnt antagonists in differentiating osteoblasts

artículo científico publicado en 2005

Modelling mosquito infection at natural parasite densities identifies drugs targeting EF2, PI4K or ATP4 as key candidates for interrupting malaria transmission

artículo científico publicado en 2017

Novel pantothenate derivatives for anti-malarial chemotherapy

artículo científico publicado en 2015

Osteo-transcriptomics of human mesenchymal stem cells: accelerated gene expression and osteoblast differentiation induced by vitamin D reveals c-MYC as an enhancer of BMP2-induced osteogenesis

artículo científico

Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183

artículo científico publicado en 2022

Predicting the therapeutic efficacy of MSC in bone tissue engineering using the molecular marker CADM1

scientific article published on 26 March 2013

Repurposing isoxazoline veterinary drugs for control of vector-borne human diseases

article published in the Proceedings of the National Academy of Sciences of the United States of America

Salinomycin and other ionophores as a new class of antimalarial drugs with transmission-blocking activity

artículo científico publicado en 2015

Structural Basis for Agonism and Antagonism for a Set of Chemically Related Progesterone Receptor Modulators

artículo científico publicado en 2011

TSLP is differentially regulated by vitamin D3 and cytokines in human skin

artículo científico publicado en 2015

Targeting Plasmodium PI(4)K to eliminate malaria

artículo científico publicado en 2013

The effect of PKC activation and inhibition on osteogenic differentiation of human mesenchymal stem cells

artículo científico publicado en 2010

The role of collagen crosslinking in differentiation of human mesenchymal stem cells and MC3T3-E1 cells

artículo científico publicado en 2009

The transcriptome's drugable frequenters

artículo científico publicado en 2005

X-ray Structures of Progesterone Receptor Ligand Binding Domain in Its Agonist State Reveal Differing Mechanisms for Mixed Profiles of 11 -Substituted Steroids

artículo científico publicado en 2012

Lista de obras de

A NF54 Reporter Line Expressing mCherry-Luciferase in Gametocytes, Sporozoites, and Liver-Stages

A Plasmodium falciparum screening assay for anti-gametocyte drugs based on parasite lactate dehydrogenase detection

A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria

A new P. falciparum gametocyte drug screening assay based on pLDH detection.

A novel multiple-stage antimalarial agent that inhibits protein synthesis

A potent series targeting the malarial cGMP-dependent protein kinase clears infection and blocks transmission.

A scalable assessment of Plasmodium falciparum transmission in the standard membrane-feeding assay, using transgenic parasites expressing green fluorescent protein-luciferase

A semi-automated luminescence based standard membrane feeding assay identifies novel small molecules that inhibit transmission of malaria parasites by mosquitoes

A simple and predictive phenotypic High Content Imaging assay for Plasmodium falciparum mature gametocytes to identify malaria transmission blocking compounds

An inter-laboratory comparison of standard membrane-feeding assays for evaluation of malaria transmission-blocking vaccines

Analysis of a Multi-component Multi-stage Malaria Vaccine Candidate--Tackling the Cocktail Challenge

Analysis of the dose-dependent stage-specific in vitro efficacy of a multi-stage malaria vaccine candidate cocktail

Antimalarial agents against both sexual and asexual parasites stages: structure-activity relationships and biological studies of the Malaria Box compound 1-[5-(4-bromo-2-chlorophenyl)furan-2-yl]-N-[(piperidin-4-yl)methyl]methanamine (MMV019918) and a

Antimalarial efficacy of MMV390048, an inhibitor of Plasmodium phosphatidylinositol 4-kinase.

Antimalarial pantothenamide metabolites target acetyl-coenzyme A biosynthesis in Plasmodium falciparum

Bioassay development

Breast cancer oestrogen independence mediated by BCAR1 or BCAR3 genes is transmitted through mechanisms distinct from the oestrogen receptor signalling pathway or the epidermal growth factor receptor signalling pathway

Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose-Efficacy Modeling

Comprehensive microarray analysis of bone morphogenetic protein 2-induced osteoblast differentiation resulting in the identification of novel markers for bone development

Corrigendum: A novel multiple-stage antimalarial agent that inhibits protein synthesis

DNA methylation restricts spontaneous multi-lineage differentiation of mesenchymal progenitor cells, but is stable during growth factor-induced terminal differentiation ⬇️

Delineation of amplification, hybridization and location effects in microarray data yields better-quality normalization

Diversity-oriented synthesis yields novel multistage antimalarial inhibitors

Effect of chordin-like 1 on MC3T3-E1 and human mesenchymal stem cells

Epigenetics: DNA demethylation promotes skeletal myotube maturation.

Functional antibodies against sporozoites are associated with a longer time to qPCR-detected infection among schoolchildren in Burkina Faso

Gene array analysis of bone morphogenetic protein type I receptor-induced osteoblast differentiation.

High-throughput assay for the identification of compounds regulating osteogenic differentiation of human mesenchymal stromal cells

Identification of novel bacterial M.SssI DNA methyltransferase inhibitors.

Identification of novel regulators associated with early-phase osteoblast differentiation

MicroRNA miR-378 promotes BMP2-induced osteogenic differentiation of mesenchymal progenitor cells

Microarray analysis on Runx2-deficient mouse embryos reveals novel Runx2 functions and target genes during intramembranous and endochondral bone formation

Microarray analysis reveals expression regulation of Wnt antagonists in differentiating osteoblasts

Modelling mosquito infection at natural parasite densities identifies drugs targeting EF2, PI4K or ATP4 as key candidates for interrupting malaria transmission

Novel pantothenate derivatives for anti-malarial chemotherapy

Osteo-transcriptomics of human mesenchymal stem cells: accelerated gene expression and osteoblast differentiation induced by vitamin D reveals c-MYC as an enhancer of BMP2-induced osteogenesis

Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183

Predicting the therapeutic efficacy of MSC in bone tissue engineering using the molecular marker CADM1

Repurposing isoxazoline veterinary drugs for control of vector-borne human diseases

Salinomycin and other ionophores as a new class of antimalarial drugs with transmission-blocking activity

Structural Basis for Agonism and Antagonism for a Set of Chemically Related Progesterone Receptor Modulators

TSLP is differentially regulated by vitamin D3 and cytokines in human skin

Targeting Plasmodium PI(4)K to eliminate malaria

The effect of PKC activation and inhibition on osteogenic differentiation of human mesenchymal stem cells

The role of collagen crosslinking in differentiation of human mesenchymal stem cells and MC3T3-E1 cells

The transcriptome's drugable frequenters

X-ray Structures of Progesterone Receptor Ligand Binding Domain in Its Agonist State Reveal Differing Mechanisms for Mixed Profiles of 11 -Substituted Steroids