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Clinical assessment of HNF1A and GCK variants and identification of a novel mutation causing MODY2

artículo científico publicado en 2012

Decoding inflammation, its causes, genomic responses, and emerging countermeasures

scientific article published on 28 August 2019

EGF receptor-mediated FUS phosphorylation promotes its nuclear translocation and fibrotic signaling

artículo científico publicado en 2020

Hyperlipidemic hypersensitivity to lethal microbial inflammation and its reversal by selective targeting of nuclear transport shuttles

artículo científico publicado en 2021

In vivo islet protection by a nuclear import inhibitor in a mouse model of type 1 diabetes

artículo científico publicado en 2010

Interactive sites in the MyD88 Toll/interleukin (IL) 1 receptor domain responsible for coupling to the IL1beta signaling pathway

artículo científico publicado en 2005

Lethality in a Murine Model of Pulmonary Anthrax is Reduced by Combining Nuclear Transport Modifier with Antimicrobial Therapy ⬇️

artículo científico publicado el 26 de enero de 2012

Nuclear transport modulation reduces hypercholesterolemia, atherosclerosis, and fatty liver

artículo científico publicado en 2013

Protection from Endotoxin Shock by Selective Targeting of Proinflammatory Signaling to the Nucleus Mediated by Importin Alpha 5

scientific article published on 18 September 2019

Suppression of acute lung inflammation by intracellular peptide delivery of a nuclear import inhibitor

artículo científico publicado en 2009

Survival, bacterial clearance and thrombocytopenia are improved in polymicrobial sepsis by targeting nuclear transport shuttles.

artículo científico publicado en 2017

Targeting nuclear import shuttles, importins/karyopherins alpha by a peptide mimicking the NFκB1/p50 nuclear localization sequence

artículo científico publicado en 2013

The "genomic storm" induced by bacterial endotoxin is calmed by a nuclear transport modifier that attenuates localized and systemic inflammation

artículo científico publicado en 2014

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