Lista de obras -

A function for cyclin D1 in DNA repair uncovered by protein interactome analyses in human cancers

artículo científico publicado en 2011

A mitotic CDK5-PP4 phospho-signaling cascade primes 53BP1 for DNA repair in G1

scientific article published on 18 September 2019

A systematic screen for CDK4/6 substrates links FOXM1 phosphorylation to senescence suppression in cancer cells

artículo científico publicado en 2011

Aberrant cell cycle progression and endoreplication in regenerating livers of mice that lack a single E-type cyclin

artículo científico publicado en 2009

Acetylation-dependent regulation of PD-L1 nuclear translocation dictates the efficacy of anti-PD-1 immunotherapy

artículo científico publicado en 2020

Acquired resistance to combined BET and CDK4/6 inhibition in triple-negative breast cancer

artículo científico publicado en 2020

Canonical and atypical E2Fs regulate the mammalian endocycle

scientific journal article

Cell cycle progression without cyclin D-CDK4 and cyclin D-CDK6 complexes

artículo científico publicado en 2005

Cell cycle proteins as promising targets in cancer therapy

artículo científico publicado en 2017

Cell-cycle-regulated activation of Akt kinase by phosphorylation at its carboxyl terminus

artículo científico publicado en 2014

Cerebellar cortical lamination and foliation require cyclin A2

artículo científico publicado en 2014

Concurrent deletion of cyclin E1 and cyclin-dependent kinase 2 in hepatocytes inhibits DNA replication and liver regeneration in mice

artículo científico publicado en 2013

Critical role for cyclin D2 in BCR/ABL-induced proliferation of hematopoietic cells

scientific journal article

Cyclin A is redundant in fibroblasts but essential in hematopoietic and embryonic stem cells

scientific journal article

Cyclin A2 promotes DNA repair in the brain during both development and aging.

artículo científico publicado en 2016

Cyclin C is a haploinsufficient tumour suppressor

artículo científico publicado en 2014

Cyclin D activates the Rb tumor suppressor by mono-phosphorylation

artículo científico publicado en 2014

Cyclin D1 fine-tunes the neurogenic output of embryonic retinal progenitor cells.

artículo científico publicado en 2009

Cyclin D1 represses gluconeogenesis via inhibition of the transcriptional coactivator PGC1α

artículo científico publicado en 2014

Cyclin D1-Cdk4 controls glucose metabolism independently of cell cycle progression

artículo científico publicado en 2014

Cyclin D1-dependent kinase activity in murine development and mammary tumorigenesis

artículo científico publicado en 2006

Cyclin D3 coordinates the cell cycle during differentiation to regulate erythrocyte size and number

artículo científico publicado en 2012

Cyclin E Constrains Cdk5 Activity to Regulate Synaptic Plasticity and Memory Formation ⬇️

artículo científico publicado el 22 de septiembre de 2011

Cyclin E ablation in the mouse

scientific journal article

Cyclins D2 and D1 are essential for postnatal pancreatic beta-cell growth

artículo científico publicado en 2005

Development of mice expressing a single D-type cyclin.

artículo científico publicado en 2002

E-type cyclins modulate telomere integrity in mammalian male meiosis

artículo científico publicado en 2015

FoxM1 is a downstream target and marker of HER2 overexpression in breast cancer

artículo científico publicado en 2009

Genetic replacement of cyclin D1 function in mouse development by cyclin D2.

artículo científico publicado en 2005

Increased lysosomal biomass is responsible for the resistance of triple-negative breast cancers to CDK4/6 inhibition

scientific article published on 17 June 2020

MED12 Regulates HSC-Specific Enhancers Independently of Mediator Kinase Activity to Control Hematopoiesis

scientific article published on 24 August 2016

Non-canonical functions of cell cycle cyclins and cyclin-dependent kinases

artículo científico publicado en 2016

Notch signaling mediates G1/S cell-cycle progression in T cells via cyclin D3 and its dependent kinases

artículo científico publicado en 2008

Overcoming Therapeutic Resistance in HER2-Positive Breast Cancers with CDK4/6 Inhibitors

artículo científico publicado en 2016

PP2A-mediated regulation of Ras signaling in G2 is essential for stable quiescence and normal G1 length

artículo científico publicado en 2014

Perturbed myoepithelial cell differentiation in BRCA mutation carriers and in ductal carcinoma in situ

artículo científico publicado en 2019

Postsynaptic GABAB receptor activity regulates excitatory neuronal architecture and spatial memory

artículo científico publicado en 2014

Proteomic Identification of a Direct Role for Cyclin D1 in DNA Damage Repair ⬇️

artículo científico publicado el 22 de agosto de 2012

Proteomic Landscape of Tissue-Specific Cyclin E Functions in Vivo.

artículo científico publicado en 2016

Requirement for CDK4 kinase function in breast cancer

scientific journal article

Requirement for cyclin D3 in germinal center formation and function.

artículo científico publicado en 2010

Requirement for cyclin D3 in lymphocyte development and T cell leukemias

scientific journal article

Targeting cyclins and cyclin-dependent kinases in cancer: lessons from mice, hopes for therapeutic applications in human

artículo científico publicado en 2006

The E4F protein is required for mitotic progression during embryonic cell cycles

scientific journal article

The Requirement for Cyclin D Function in Tumor Maintenance ⬇️

artículo científico publicado el 16 de octubre de 2012

The cell cycle in stem cell proliferation, pluripotency and differentiation

scientific article published on 02 September 2019

The cyclin D1-CDK4 oncogenic interactome enables identification of potential novel oncogenes and clinical prognosis

artículo científico publicado en 2014

The kinase-independent, second life of CDK6 in transcription

artículo científico publicado en 2013

The retinoblastoma protein regulates pericentric heterochromatin

artículo científico publicado en 2006

p600 Plays Essential Roles in Fetal Development

artículo científico publicado en 2013

β-Selection-Induced Proliferation Is Required for αβ T Cell Differentiation ⬇️

artículo científico publicado el 16 de noviembre de 2012

Lista de obras de

A function for cyclin D1 in DNA repair uncovered by protein interactome analyses in human cancers

A mitotic CDK5-PP4 phospho-signaling cascade primes 53BP1 for DNA repair in G1

A systematic screen for CDK4/6 substrates links FOXM1 phosphorylation to senescence suppression in cancer cells

Aberrant cell cycle progression and endoreplication in regenerating livers of mice that lack a single E-type cyclin

Acetylation-dependent regulation of PD-L1 nuclear translocation dictates the efficacy of anti-PD-1 immunotherapy

Acquired resistance to combined BET and CDK4/6 inhibition in triple-negative breast cancer

Canonical and atypical E2Fs regulate the mammalian endocycle

Cell cycle progression without cyclin D-CDK4 and cyclin D-CDK6 complexes

Cell cycle proteins as promising targets in cancer therapy

Cell-cycle-regulated activation of Akt kinase by phosphorylation at its carboxyl terminus

Cerebellar cortical lamination and foliation require cyclin A2

Concurrent deletion of cyclin E1 and cyclin-dependent kinase 2 in hepatocytes inhibits DNA replication and liver regeneration in mice

Critical role for cyclin D2 in BCR/ABL-induced proliferation of hematopoietic cells

Cyclin A is redundant in fibroblasts but essential in hematopoietic and embryonic stem cells

Cyclin A2 promotes DNA repair in the brain during both development and aging.

Cyclin C is a haploinsufficient tumour suppressor

Cyclin D activates the Rb tumor suppressor by mono-phosphorylation

Cyclin D1 fine-tunes the neurogenic output of embryonic retinal progenitor cells.

Cyclin D1 represses gluconeogenesis via inhibition of the transcriptional coactivator PGC1α

Cyclin D1-Cdk4 controls glucose metabolism independently of cell cycle progression

Cyclin D1-dependent kinase activity in murine development and mammary tumorigenesis

Cyclin D3 coordinates the cell cycle during differentiation to regulate erythrocyte size and number

Cyclin E Constrains Cdk5 Activity to Regulate Synaptic Plasticity and Memory Formation ⬇️

Cyclin E ablation in the mouse

Cyclins D2 and D1 are essential for postnatal pancreatic beta-cell growth

Development of mice expressing a single D-type cyclin.

E-type cyclins modulate telomere integrity in mammalian male meiosis

FoxM1 is a downstream target and marker of HER2 overexpression in breast cancer

Genetic replacement of cyclin D1 function in mouse development by cyclin D2.

Increased lysosomal biomass is responsible for the resistance of triple-negative breast cancers to CDK4/6 inhibition

MED12 Regulates HSC-Specific Enhancers Independently of Mediator Kinase Activity to Control Hematopoiesis

Non-canonical functions of cell cycle cyclins and cyclin-dependent kinases

Notch signaling mediates G1/S cell-cycle progression in T cells via cyclin D3 and its dependent kinases

Overcoming Therapeutic Resistance in HER2-Positive Breast Cancers with CDK4/6 Inhibitors

PP2A-mediated regulation of Ras signaling in G2 is essential for stable quiescence and normal G1 length

Perturbed myoepithelial cell differentiation in BRCA mutation carriers and in ductal carcinoma in situ

Postsynaptic GABAB receptor activity regulates excitatory neuronal architecture and spatial memory

Proteomic Identification of a Direct Role for Cyclin D1 in DNA Damage Repair ⬇️

Proteomic Landscape of Tissue-Specific Cyclin E Functions in Vivo.

Requirement for CDK4 kinase function in breast cancer

Requirement for cyclin D3 in germinal center formation and function.

Requirement for cyclin D3 in lymphocyte development and T cell leukemias

Targeting cyclins and cyclin-dependent kinases in cancer: lessons from mice, hopes for therapeutic applications in human

The E4F protein is required for mitotic progression during embryonic cell cycles

The Requirement for Cyclin D Function in Tumor Maintenance ⬇️

The cell cycle in stem cell proliferation, pluripotency and differentiation

The cyclin D1-CDK4 oncogenic interactome enables identification of potential novel oncogenes and clinical prognosis

The kinase-independent, second life of CDK6 in transcription

The retinoblastoma protein regulates pericentric heterochromatin

p600 Plays Essential Roles in Fetal Development

β-Selection-Induced Proliferation Is Required for αβ T Cell Differentiation ⬇️