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Advanced Analysis of Photoreceptor Outer Segment Phagocytosis by RPE Cells in Culture

article

Alphavbeta5 integrin receptors at the apical surface of the RPE: one receptor, two functions.

artículo científico publicado en 2008

Altered rhythm of photoreceptor outer segment phagocytosis in beta5 integrin knockout mice.

artículo científico publicado en 2006

Analysis of Photoreceptor Rod Outer Segment Phagocytosis by RPE Cells In Situ

artículo científico publicado el 1 de enero de 2013

Analysis of photoreceptor outer segment phagocytosis by RPE cells in culture

artículo científico publicado en 2013

Annexin A5 regulates surface αvβ5 integrin for retinal clearance phagocytosis

artículo científico publicado en 2019

Changes in retinal pigment epithelial gene expression induced by rod outer segment uptake

artículo científico publicado en 2004

Comment on 'Integrin alphavbbeta is not required for the phagocytosis of photoreceptor outer segments by cultured retinal pigment epithelial cells' by M.O. Hall, T.A. Abrams and B.L. Burgess [Exp. Eye Res. 77 (2003) 281-286].

artículo científico publicado en 2004

Dietary antioxidants prevent age-related retinal pigment epithelium actin damage and blindness in mice lacking αvβ5 integrin

artículo científico publicado en 2011

Differences in Diurnal Rhythm of Rod Outer Segment Renewal between 129T2/SvEmsJ and C57BL/6J Mice

artículo científico publicado en 2022

Dimerization deficiency of enigmatic retinitis pigmentosa-linked rhodopsin mutants

artículo científico publicado en 2016

Diurnal, localized exposure of phosphatidylserine by rod outer segment tips in wild-type but notItgb5−/−orMfge8−/−mouse retina

artículo científico publicado el 7 de mayo de 2012

Efficiency of Membrane Protein Expression Following Infection with Recombinant Adenovirus of Polarized Non-Transformed Human Retinal Pigment Epithelial Cells.

artículo científico publicado en 2016

Essential diurnal Rac1 activation during retinal phagocytosis requires αvβ5 integrin but not tyrosine kinases focal adhesion kinase or Mer tyrosine kinase

artículo científico publicado el 19 de enero de 2012

Essential role for MFG-E8 as ligand for alphavbeta5 integrin in diurnal retinal phagocytosis

artículo científico publicado en 2007

Expression and Characterisation of αvβ5 Integrin on Intestinal Macrophages

artículo científico publicado en 2018

Expression of ABCA4 in the retinal pigment epithelium and its implications for Stargardt macular degeneration

article published in the Proceedings of the National Academy of Sciences of the United States of America

Expression of the Integrin Coreceptor Transglutaminase-2 in the RPE In Vivo and in Culture

artículo científico publicado el 1 de enero de 2012

Focal adhesion kinase signaling promotes phagocytosis of integrin-bound photoreceptors

scientific journal article

Independent roles of methionine sulfoxide reductase A in mitochondrial ATP synthesis and as antioxidant in retinal pigment epithelial cells

artículo científico publicado en 2013

Lack of alphavbeta5 integrin receptor or its ligand MFG-E8: distinct effects on retinal function

artículo científico publicado en 2008

Lack of effect of microfilament or microtubule cytoskeleton-disrupting agents on restriction of externalized phosphatidylserine to rod photoreceptor outer segment tips.

artículo científico publicado en 2014

Large-scale purification of porcine or bovine photoreceptor outer segments for phagocytosis assays on retinal pigment epithelial cells

artículo científico publicado en 2014

Light-induced oxidation of photoreceptor outer segment phospholipids generates ligands for CD36-mediated phagocytosis by retinal pigment epithelium: a potential mechanism for modulating outer segment phagocytosis under oxidant stress conditions.

artículo científico publicado en 2005

Live Imaging of LysoTracker-Labelled Phagolysosomes Tracks Diurnal Phagocytosis of Photoreceptor Outer Segment Fragments in Rat RPE Tissue Ex Vivo.

artículo científico publicado en 2016

Loss of synchronized retinal phagocytosis and age-related blindness in mice lacking alphavbeta5 integrin.

artículo científico publicado en 2004

MerTK activation during RPE phagocytosis in vivo requires alphaVbeta5 integrin

artículo científico publicado en 2006

Microglia Inhibition Delays Retinal Degeneration Due to MerTK Phagocytosis Receptor Deficiency

artículo científico publicado en 2020

Neural retina and MerTK-independent apical polarity of alphavbeta5 integrin receptors in the retinal pigment epithelium

artículo científico publicado en 2010

No Difference Between Age-Matched Male and Female C57BL/6J Mice in Photopic and Scotopic Electroretinogram a- and b-Wave Amplitudes or in Peak Diurnal Outer Segment Phagocytosis by the Retinal Pigment Epithelium

scientific article published on 01 January 2019

Non-invasive in vivo fluorescence imaging of apoptotic retinal photoreceptors

artículo científico publicado en 2019

Nonsynaptic localization of the excitatory amino acid transporter 4 in photoreceptors.

artículo científico publicado en 2005

Novel role for alphavbeta5-integrin in retinal adhesion and its diurnal peak

artículo científico publicado en 2005

PI 3-kinase independent role for AKT in F-actin regulation during outer segment phagocytosis by RPE cells

artículo científico publicado el 10 de mayo de 2013

Quantified F-Actin Morphology Is Predictive of Phagocytic Capacity of Stem Cell-Derived Retinal Pigment Epithelium

artículo científico publicado en 2018

Regulation of Phagolysosomal Digestion by Caveolin-1 of the Retinal Pigment Epithelium Is Essential for Vision

artículo científico publicado en 2016

Regulation of phagocytosis by Rho GTPases

artículo científico publicado en 2015

Retinal Pre-Conditioning by CD59a Knockout Protects against Light-Induced Photoreceptor Degeneration.

artículo científico publicado en 2016

Retinal pigment epithelial cells use a MerTK-dependent mechanism to limit the phagocytic particle binding activity of αvβ5 integrin

artículo científico publicado en 2012

Role of alphavbeta5 integrin in regulating phagocytosis by the retinal pigment epithelium.

artículo científico publicado en 2003

Semaphorin4D-PlexinB1 Signaling Attenuates Photoreceptor Outer Segment Phagocytosis by Reducing Rac1 Activity of RPE Cells

artículo científico publicado en 2017

Sex-specific multi-level 3D genome dynamics in the mouse brain

artículo científico publicado en 2022

Tetraspanin CD81 is required for the alpha v beta5-integrin-dependent particle-binding step of RPE phagocytosis

scientific journal article

The Developmental Stage of Adult Human Stem Cell-Derived Retinal Pigment Epithelium Cells Influences Transplant Efficacy for Vision Rescue

artículo científico publicado en 2017

The age lipid A2E and mitochondrial dysfunction synergistically impair phagocytosis by retinal pigment epithelial cells

artículo científico publicado en 2008

The age lipid A2E and mitochondrial dysfunction synergistically impair phagocytosis by retinal pigment epithelial cells.

artículo científico publicado en 2013

The lipofuscin component A2E selectively inhibits phagolysosomal degradation of photoreceptor phospholipid by the retinal pigment epithelium

artículo científico publicado en 2002

The lipofuscin fluorophore A2E perturbs cholesterol metabolism in retinal pigment epithelial cells

artículo científico publicado en 2007

Tissue-specific modifier alleles determine Mertk loss-of-function traits

artículo científico publicado en 2022

Understanding photoreceptor outer segment phagocytosis: use and utility of RPE cells in culture

artículo científico publicado en 2014

αvβ5 Integrin-Dependent Diurnal Phagocytosis of Shed Photoreceptor Outer Segments by RPE Cells Is Independent of the Integrin Coreceptor Transglutaminase-2

artículo científico publicado el 1 de enero de 2012