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An oxindole efflux inhibitor potentiates azoles and impairs virulence in the fungal pathogen Candida auris

artículo científico publicado en 2020

Chemical Synthesis Enables Structural Reengineering of Aglaroxin C Leading to Inhibition Bias for Hepatitis C Viral Infection

artículo científico publicado en 2019

Design and Synthesis of Fungal-Selective Resorcylate Aminopyrazole Hsp90 Inhibitors

scientific article published on 26 September 2019

Diastereodivergent Synthesis of Chiral Tetrahydropyrrolodiazepinediones via a One-Pot Intramolecular aza-Michael/Lactamization Sequence

scientific article published on 05 December 2018

Discovery of Macrocyclic Inhibitors of Apurinic/Apyrimidinic Endonuclease 1

scientific article published on 06 February 2019

Heat Shock Factor 1-dependent extracellular matrix remodeling mediates the transition from chronic intestinal inflammation to colon cancer

artículo científico publicado en 2020

Intercepted Retro-Nazarov Reaction: Syntheses of Amidino-Rocaglate Derivatives and Their Biological Evaluation as eIF4A Inhibitors

scientific article published on 30 July 2019

Oxo-aglaiastatin-Mediated Inhibition of Translation Initiation

artículo científico publicado en 2019

Structural basis for species-selective targeting of Hsp90 in a pathogenic fungus.

artículo científico publicado en 2019

Targeting translation initiation by synthetic rocaglates for treating MYC-driven lymphomas

artículo científico publicado en 2019

eIF4A supports an oncogenic translation program in pancreatic ductal adenocarcinoma

scientific article published on 13 November 2019

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