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Antitumor activity of HM781-36B, a pan-HER tyrosine kinase inhibitor, in HER2-amplified breast cancer cells

artículo científico publicado en 2012

Antitumor activity of HM781-36B, an irreversible Pan-HER inhibitor, alone or in combination with cytotoxic chemotherapeutic agents in gastric cancer ⬇️

artículo científico publicado el 28 de marzo de 2011

Antitumor activity of saracatinib (AZD0530), a c-Src/Abl kinase inhibitor, alone or in combination with chemotherapeutic agents in gastric cancer

artículo científico publicado en 2012

Combination of EGFR and MEK1/2 inhibitor shows synergistic effects by suppressing EGFR/HER3-dependent AKT activation in human gastric cancer cells

artículo científico publicado en 2009

Down-regulation of mitogen-inducible gene 6, a negative regulator of EGFR, enhances resistance to MEK inhibition in KRAS mutant cancer cells

artículo científico publicado en 2011

Expedited Safety Reporting to Sponsors Through the Implementation of an Alert System for Clinical Trial Management at an Academic Medical Center: Retrospective Design Study

artículo científico publicado en 2020

Feasibility, safety, and adequacy of research biopsies for cancer clinical trials at an academic medical center

scientific article published on 12 August 2019

Gene silencing of EREG mediated by DNA methylation and histone modification in human gastric cancers

artículo científico publicado en 2012

Heterodimerization of glycosylated insulin-like growth factor-1 receptors and insulin receptors in cancer cells sensitive to anti-IGF1R antibody

artículo científico publicado en 2012

KRAS mutant lung cancer cells are differentially responsive to MEK inhibitor due to AKT or STAT3 activation: implication for combinatorial approach

artículo científico publicado en 2010

Lapatinib, a dual EGFR and HER2 tyrosine kinase inhibitor, downregulates thymidylate synthase by inhibiting the nuclear translocation of EGFR and HER2.

artículo científico publicado en 2009

RAD001 shows activity against gastric cancer cells and overcomes 5-FU resistance by downregulating thymidylate synthase ⬇️

artículo científico publicado el 19 de agosto de 2010

RAD51C-deficient cancer cells are highly sensitive to the PARP inhibitor olaparib

artículo científico publicado en 2013

Sunitinib synergizes the antitumor effect of cisplatin via modulation of ERCC1 expression in models of gastric cancer ⬇️

artículo científico publicado el 20 de enero de 2012

The growth inhibitory effect of lapatinib, a dual inhibitor of EGFR and HER2 tyrosine kinase, in gastric cancer cell lines

artículo científico publicado en 2008

The irreversible pan-HER inhibitor PF00299804 alone or combined with gemcitabine has an antitumor effect in biliary tract cancer cell lines ⬇️

artículo científico publicado el 25 de diciembre de 2011

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