Lista de obras - Fábio Klamt - Dominio Público Uruguay

3-O-Methylquercetin from Achyrocline satureioides-cytotoxic activity against A375-derived human melanoma cell lines and its incorporation into cyclodextrins-hydrogels for topical administration

artículo científico publicado en 2021

A systematic review of human antioxidant genes.

artículo científico publicado en 2009

Achyrocline satureioides compounds, achyrobichalcone and 3-O-methylquercetin, induce mitochondrial dysfunction and apoptosis in human breast cancer cell lines

artículo científico publicado en 2020

Activated peripheral blood mononuclear cell mediators trigger astrocyte reactivity

scientific article published on 05 June 2019

Acute treatment with diphenyl diselenide inhibits glutamate uptake into rat hippocampal slices and modifies glutamate transporters, SNAP-25, and GFAP immunocontent.

artículo científico publicado en 2009

All-trans retinoic acid induces free radical generation and modulate antioxidant enzyme activities in rat sertoli cells

artículo científico publicado en 2006

Antioxidant defense capacity of ovarian tissue after vitrification in a metal closed system

Antioxidant treatment reverses mitochondrial dysfunction in a sepsis animal model.

artículo científico publicado en 2008

Bioinformatics approach for the validation of non-small cell lung cancer biomarkers

scientific article published on 01 January 2011

Bioinformatics approach to evaluate differential gene expression of M1/M2 macrophage phenotypes and antioxidant genes in atherosclerosis.

artículo científico publicado en 2014

Brazilian marine sponge Polymastia janeirensis induces apoptotic cell death in human U138MG glioma cell line, but not in a normal cell culture

artículo científico publicado en 2008

CFL1 expression levels as a prognostic and drug resistance marker in nonsmall cell lung cancer

artículo científico publicado en 2010

Can electrons travel through actin microfilaments and generate oxidative stress in retinol treated Sertoli cell?

scientific article published on 03 January 2007

Cannabidiol Exposure During Neuronal Differentiation Sensitizes Cells Against Redox-Active Neurotoxins

artículo científico publicado en 2014

Cannabinoid-Based Therapies and Brain Development: Potential Harmful Effect of Early Modulation of the Endocannabinoid System

scientific article published on 01 August 2018

Cholinergic Differentiation of Human Neuroblastoma SH-SY5Y Cell Line and Its Potential Use as an In vitro Model for Alzheimer's Disease Studies

scientific article published on 29 April 2019

Cofilin-1 levels and intracellular localization are associated with melanoma prognosis in a cohort of patients.

artículo científico publicado en 2018

Cofilin/actin rod formation by dysregulation of cofilin-1 activity as a central initial step in neurodegeneration

artículo científico

Combined Treatments with a Retinoid Receptor Agonist and Epigenetic Modulators in Human Neuroblastoma Cells

artículo científico publicado en 2016

Comparison between proliferative and neuron-like SH-SY5Y cells as an in vitro model for Parkinson disease studies

artículo científico publicado en 2010

Convalescent Plasma Therapy on Patients with Severe or Life-Threatening COVID-19: A Metadata Analysis

artículo científico publicado en 2020

Damage-associated molecular patterns (DAMPs) related to immunogenic cell death are differentially triggered by clinically relevant chemotherapeutics in lung adenocarcinoma cells

artículo científico publicado en 2020

Depression and Mania Induce Pro-inflammatory Activation of Macrophages Following Application of Serum from Individuals with Bipolar Disorder

artículo científico publicado en 2018

EGR3 Immediate Early Gene and the Brain-Derived Neurotrophic Factor in Bipolar Disorder

artículo científico publicado en 2018

Enhanced UV-mediated free radical generation; DNA and mitochondrial damage caused by retinol supplementation

artículo científico publicado en 2003

Eugenia uniflora leaf essential oil promotes mitochondrial dysfunction in Drosophila melanogaster through the inhibition of oxidative phosphorylation

artículo científico publicado en 2017

Evaluation of the Neurotoxic/Neuroprotective Role of Organoselenides Using Differentiated Human Neuroblastoma SH-SY5Y Cell Line Challenged with 6-Hydroxydopamine ⬇️

artículo científico publicado el 20 de enero de 2012

Evidence that the major metabolites accumulating in medium-chain acyl-CoA dehydrogenase deficiency disturb mitochondrial energy homeostasis in rat brain

artículo científico publicado en 2009

Extracts of marine sponge Polymastia janeirensis induce oxidative cell death through a caspase-9 apoptotic pathway in human U138MG glioma cell line

artículo científico publicado en 2008

Genotoxicity, recombinogenicity and cellular preneoplasic transformation induced by vitamin A supplementation

artículo científico publicado en 2003

High cofilin-1 levels correlate with cisplatin resistance in lung adenocarcinomas

artículo científico publicado en 2013

Imbalance in redox status is associated with tumor aggressiveness and poor outcome in lung adenocarcinoma patients

artículo científico

Immunosenescence Induced by Plasma from Individuals with Obesity Caused Cell Signaling Dysfunction and Inflammation

artículo científico publicado en 2017

Impaired endoplasmic reticulum stress response in bipolar disorder: cellular evidence of illness progression

artículo científico publicado en 2014

In vitro evaluation of antitumoral efficacy of catalase in combination with traditional chemotherapeutic drugs against human lung adenocarcinoma cells.

artículo científico publicado en 2016

In vitro optimization of retinoic acid-induced neuritogenesis and TH endogenous expression in human SH-SY5Y neuroblastoma cells by the antioxidant Trolox

artículo científico publicado en 2011

Increased oxidative damage in carriers of the germline TP53 p.R337H mutation

artículo científico publicado en 2012

Inhibition of MDR1 expression by retinol treatment increases sensitivity to etoposide (VP16) in human neoplasic cell line

artículo científico publicado en 2008

Integrated Transcriptomics Establish Macrophage Polarization Signatures and have Potential Applications for Clinical Health and Disease

artículo científico publicado en 2015

Integrated transcriptomics reveals master regulators of lung adenocarcinoma and novel repositioning of drug candidates

artículo científico publicado en 2019

Isolation of achyrobichalcone from Achyrocline satureioides by high- speed countercurrent chromatography

artículo científico publicado en 2015

Lung oxidative response after acute coal dust exposure

artículo científico publicado en 2004

Master Regulators Connectivity Map: A Transcription Factors-Centered Approach to Drug Repositioning

scientific article published on 02 July 2018

Metabolic rewiring in melanoma drug-resistant cells

scientific article published on 24 May 2020

Metabotropic glutamate receptors as a new therapeutic target for malignant gliomas

artículo científico publicado en 2017

Methylglyoxal-Induced Protection Response and Toxicity: Role of Glutathione Reductase and Thioredoxin Systems.

artículo científico publicado en 2017

Mimicking Parkinson's Disease in a Dish: Merits and Pitfalls of the Most Commonly used Dopaminergic In Vitro Models.

artículo científico publicado en 2017

Modulation of oxidative stress in response to gamma-radiation in human glioma cell lines

artículo científico publicado en 2003

Morphological and oxidative alterations on Sertoli cells cytoskeleton due to retinol-induced reactive oxygen species

artículo científico publicado en 2005

Nicotinamide N-methyltransferase catalyses the N-methylation of the endogenous β-carboline norharman: evidence for a novel detoxification pathway.

artículo científico publicado en 2016

Nicotinamide N-methyltransferase expression in SH-SY5Y human neuroblastoma cells decreases oxidative stress

artículo científico publicado en 2020

Nicotinamide N-methyltransferase increases complex I activity in SH-SY5Y cells via sirtuin 3.

artículo científico publicado en 2015

Oxidative parameters and mortality in sepsis induced by cecal ligation and perforation

scientific article published on 29 May 2003

Oxidative stress associates with aggressiveness in lung large-cell carcinoma.

artículo científico publicado en 2015

Peripheral biomarkers and illness activity in bipolar disorder

artículo científico publicado en 2010

Peripheral oxidative damage in early-stage mood disorders: a nested population-based case-control study

scientific article published on 19 October 2011

Potential crosstalk between cofilin-1 and EGFR pathways in cisplatin resistance of non-small-cell lung cancer

artículo científico publicado en 2015

Potential predictive value of cofilin-1 for metastasis occurrence in a small cohort of Argentinian patients with mid-low Breslow thickness melanoma

scientific article published on 08 August 2019

Preventive Physical Training Partially Preserves Heart Function and Improves Cardiac Antioxidant Responses in Rats After Myocardial Infarction Preventive Physical Training and Myocardial Infarction in Rats

artículo científico publicado en 2017

RA Differentiation Enhances Dopaminergic Features, Changes Redox Parameters, and Increases Dopamine Transporter Dependency in 6-Hydroxydopamine-Induced Neurotoxicity in SH-SY5Y Cells.

artículo científico publicado en 2017

Redox Biology of Human Cumulus Cells: Basic Concepts, Impact on Oocyte Quality, and Potential Clinical Use

artículo científico publicado en 2020

Reduced Neurite Density in Neuronal Cell Cultures Exposed to Serum of Patients with Bipolar Disorder

artículo científico publicado en 2016

Reprogramming human A375 amelanotic melanoma cells by catalase overexpression: Reversion or promotion of malignancy by inducing melanogenesis or metastasis

artículo científico publicado en 2016

Reprogramming human A375 amelanotic melanoma cells by catalase overexpression: Upregulation of antioxidant genes correlates with regression of melanoma malignancy and with malignant progression when downregulated

artículo científico publicado en 2016

Retinol and retinoic acid modulate catalase activity in Sertoli cells by distinct and gene expression-independent mechanisms.

artículo científico publicado en 2008

Retinol increases catalase activity and protein content by a reactive species-dependent mechanism in Sertoli cells.

artículo científico publicado en 2008

Retinol induces permeability transition and cytochrome c release from rat liver mitochondria

artículo científico publicado en 2005

Retinol-induced mdr1 and mdr3 modulation in cultured rat Sertoli cells is attenuated by free radical scavengers

artículo científico publicado en 2004

Scavenging and antioxidant potential of physiological taurine concentrations against different reactive oxygen/nitrogen species.

artículo científico publicado en 2010

Sertraline reduces glutamate uptake in human platelets.

artículo científico publicado en 2015

Simplified low-cost methodology to establish, histologically process and analyze three-dimensional cancer cell spheroid arrays

artículo científico publicado en 2020

Sulforaphane ameliorates the insulin responsiveness and the lipid profile but does not alter the antioxidant response in diabetic rats.

artículo científico publicado en 2016

Systemic toxicity in early-stage mood disorders

artículo científico publicado en 2011

TRF1 as a major contributor for telomeres' shortening in the context of obesity

artículo científico publicado en 2018

Taurine chloramine decreases cell viability and cytokine production in blood and spleen lymphocytes from septic rats submitted to sepsis

artículo científico publicado en 2013

The NF kappa B-mediated control of RS and JNK signaling in vitamin A-treated cells: duration of JNK-AP-1 pathway activation may determine cell death or proliferation

artículo científico publicado en 2008

The kinetic analysis of the N-methylation of 4-phenylpyridine by nicotinamide N-methyltransferase: Evidence for a novel mechanism of substrate inhibition.

artículo científico publicado en 2018

The pharmacological NFkappaB inhibitors BAY117082 and MG132 induce cell arrest and apoptosis in leukemia cells through ROS-mitochondria pathway activation

artículo científico publicado en 2009

The potential role of extracellular regulatory kinase in the survival of patients with early stage adenocarcinoma

artículo científico publicado en 2014

The prognostic impact of tumor-associated macrophages and intra-tumoral apoptosis in non-small cell lung cancer.

artículo científico

Time-related increase in mitochondrial superoxide production, biomolecule damage and antioxidant enzyme activities in cortical astrocyte cultures

artículo científico publicado en 2002

Transcriptomic analysis reveals pH-responsive antioxidant gene networks

artículo científico

Validation of cofilin-1 as a biomarker in non-small cell lung cancer: application of quantitative method in a retrospective cohort.

artículo científico

Vitamin A supplementation for different periods alters oxidative parameters in lungs of rats

artículo científico publicado en 2009

Vitamin A supplementation for different periods alters rat vascular redox parameters.

artículo científico publicado en 2010

Vitamin A supplementation induces oxidative stress and decreases the immunocontent of catalase and superoxide dismutase in rat lungs

artículo científico publicado en 2009

Vitamin A treatment induces apoptosis through an oxidant-dependent activation of the mitochondrial pathway

artículo científico publicado en 2007

cis-4-decenoic acid provokes mitochondrial bioenergetic dysfunction in rat brain

artículo científico publicado en 2010

Lista de obras de Fábio Klamt

3-O-Methylquercetin from Achyrocline satureioides-cytotoxic activity against A375-derived human melanoma cell lines and its incorporation into cyclodextrins-hydrogels for topical administration

A systematic review of human antioxidant genes.

Achyrocline satureioides compounds, achyrobichalcone and 3-O-methylquercetin, induce mitochondrial dysfunction and apoptosis in human breast cancer cell lines

Activated peripheral blood mononuclear cell mediators trigger astrocyte reactivity

Acute treatment with diphenyl diselenide inhibits glutamate uptake into rat hippocampal slices and modifies glutamate transporters, SNAP-25, and GFAP immunocontent.

All-trans retinoic acid induces free radical generation and modulate antioxidant enzyme activities in rat sertoli cells

Antioxidant defense capacity of ovarian tissue after vitrification in a metal closed system

Antioxidant treatment reverses mitochondrial dysfunction in a sepsis animal model.

Bioinformatics approach for the validation of non-small cell lung cancer biomarkers

Bioinformatics approach to evaluate differential gene expression of M1/M2 macrophage phenotypes and antioxidant genes in atherosclerosis.

Brazilian marine sponge Polymastia janeirensis induces apoptotic cell death in human U138MG glioma cell line, but not in a normal cell culture

CFL1 expression levels as a prognostic and drug resistance marker in nonsmall cell lung cancer

Can electrons travel through actin microfilaments and generate oxidative stress in retinol treated Sertoli cell?

Cannabidiol Exposure During Neuronal Differentiation Sensitizes Cells Against Redox-Active Neurotoxins

Cannabinoid-Based Therapies and Brain Development: Potential Harmful Effect of Early Modulation of the Endocannabinoid System

Cholinergic Differentiation of Human Neuroblastoma SH-SY5Y Cell Line and Its Potential Use as an In vitro Model for Alzheimer's Disease Studies

Cofilin-1 levels and intracellular localization are associated with melanoma prognosis in a cohort of patients.

Cofilin/actin rod formation by dysregulation of cofilin-1 activity as a central initial step in neurodegeneration

Combined Treatments with a Retinoid Receptor Agonist and Epigenetic Modulators in Human Neuroblastoma Cells

Comparison between proliferative and neuron-like SH-SY5Y cells as an in vitro model for Parkinson disease studies

Convalescent Plasma Therapy on Patients with Severe or Life-Threatening COVID-19: A Metadata Analysis

Damage-associated molecular patterns (DAMPs) related to immunogenic cell death are differentially triggered by clinically relevant chemotherapeutics in lung adenocarcinoma cells

Depression and Mania Induce Pro-inflammatory Activation of Macrophages Following Application of Serum from Individuals with Bipolar Disorder

EGR3 Immediate Early Gene and the Brain-Derived Neurotrophic Factor in Bipolar Disorder

Enhanced UV-mediated free radical generation; DNA and mitochondrial damage caused by retinol supplementation

Eugenia uniflora leaf essential oil promotes mitochondrial dysfunction in Drosophila melanogaster through the inhibition of oxidative phosphorylation

Evaluation of the Neurotoxic/Neuroprotective Role of Organoselenides Using Differentiated Human Neuroblastoma SH-SY5Y Cell Line Challenged with 6-Hydroxydopamine ⬇️

Evidence that the major metabolites accumulating in medium-chain acyl-CoA dehydrogenase deficiency disturb mitochondrial energy homeostasis in rat brain

Extracts of marine sponge Polymastia janeirensis induce oxidative cell death through a caspase-9 apoptotic pathway in human U138MG glioma cell line

Genotoxicity, recombinogenicity and cellular preneoplasic transformation induced by vitamin A supplementation

High cofilin-1 levels correlate with cisplatin resistance in lung adenocarcinomas

Imbalance in redox status is associated with tumor aggressiveness and poor outcome in lung adenocarcinoma patients

Immunosenescence Induced by Plasma from Individuals with Obesity Caused Cell Signaling Dysfunction and Inflammation

Impaired endoplasmic reticulum stress response in bipolar disorder: cellular evidence of illness progression

In vitro evaluation of antitumoral efficacy of catalase in combination with traditional chemotherapeutic drugs against human lung adenocarcinoma cells.

In vitro optimization of retinoic acid-induced neuritogenesis and TH endogenous expression in human SH-SY5Y neuroblastoma cells by the antioxidant Trolox

Increased oxidative damage in carriers of the germline TP53 p.R337H mutation

Inhibition of MDR1 expression by retinol treatment increases sensitivity to etoposide (VP16) in human neoplasic cell line

Integrated Transcriptomics Establish Macrophage Polarization Signatures and have Potential Applications for Clinical Health and Disease

Integrated transcriptomics reveals master regulators of lung adenocarcinoma and novel repositioning of drug candidates

Isolation of achyrobichalcone from Achyrocline satureioides by high- speed countercurrent chromatography

Lung oxidative response after acute coal dust exposure

Master Regulators Connectivity Map: A Transcription Factors-Centered Approach to Drug Repositioning

Metabolic rewiring in melanoma drug-resistant cells

Metabotropic glutamate receptors as a new therapeutic target for malignant gliomas

Methylglyoxal-Induced Protection Response and Toxicity: Role of Glutathione Reductase and Thioredoxin Systems.

Mimicking Parkinson's Disease in a Dish: Merits and Pitfalls of the Most Commonly used Dopaminergic In Vitro Models.

Modulation of oxidative stress in response to gamma-radiation in human glioma cell lines

Morphological and oxidative alterations on Sertoli cells cytoskeleton due to retinol-induced reactive oxygen species

Nicotinamide N-methyltransferase catalyses the N-methylation of the endogenous β-carboline norharman: evidence for a novel detoxification pathway.

Nicotinamide N-methyltransferase expression in SH-SY5Y human neuroblastoma cells decreases oxidative stress

Nicotinamide N-methyltransferase increases complex I activity in SH-SY5Y cells via sirtuin 3.

Oxidative parameters and mortality in sepsis induced by cecal ligation and perforation

Oxidative stress associates with aggressiveness in lung large-cell carcinoma.

Peripheral biomarkers and illness activity in bipolar disorder

Peripheral oxidative damage in early-stage mood disorders: a nested population-based case-control study

Potential crosstalk between cofilin-1 and EGFR pathways in cisplatin resistance of non-small-cell lung cancer

Potential predictive value of cofilin-1 for metastasis occurrence in a small cohort of Argentinian patients with mid-low Breslow thickness melanoma

Preventive Physical Training Partially Preserves Heart Function and Improves Cardiac Antioxidant Responses in Rats After Myocardial Infarction Preventive Physical Training and Myocardial Infarction in Rats

RA Differentiation Enhances Dopaminergic Features, Changes Redox Parameters, and Increases Dopamine Transporter Dependency in 6-Hydroxydopamine-Induced Neurotoxicity in SH-SY5Y Cells.

Redox Biology of Human Cumulus Cells: Basic Concepts, Impact on Oocyte Quality, and Potential Clinical Use

Reduced Neurite Density in Neuronal Cell Cultures Exposed to Serum of Patients with Bipolar Disorder

Reprogramming human A375 amelanotic melanoma cells by catalase overexpression: Reversion or promotion of malignancy by inducing melanogenesis or metastasis

Reprogramming human A375 amelanotic melanoma cells by catalase overexpression: Upregulation of antioxidant genes correlates with regression of melanoma malignancy and with malignant progression when downregulated

Retinol and retinoic acid modulate catalase activity in Sertoli cells by distinct and gene expression-independent mechanisms.

Retinol increases catalase activity and protein content by a reactive species-dependent mechanism in Sertoli cells.

Retinol induces permeability transition and cytochrome c release from rat liver mitochondria

Retinol-induced mdr1 and mdr3 modulation in cultured rat Sertoli cells is attenuated by free radical scavengers

Scavenging and antioxidant potential of physiological taurine concentrations against different reactive oxygen/nitrogen species.

Sertraline reduces glutamate uptake in human platelets.

Simplified low-cost methodology to establish, histologically process and analyze three-dimensional cancer cell spheroid arrays

Sulforaphane ameliorates the insulin responsiveness and the lipid profile but does not alter the antioxidant response in diabetic rats.

Systemic toxicity in early-stage mood disorders

TRF1 as a major contributor for telomeres' shortening in the context of obesity

Taurine chloramine decreases cell viability and cytokine production in blood and spleen lymphocytes from septic rats submitted to sepsis

The NF kappa B-mediated control of RS and JNK signaling in vitamin A-treated cells: duration of JNK-AP-1 pathway activation may determine cell death or proliferation

The kinetic analysis of the N-methylation of 4-phenylpyridine by nicotinamide N-methyltransferase: Evidence for a novel mechanism of substrate inhibition.

The pharmacological NFkappaB inhibitors BAY117082 and MG132 induce cell arrest and apoptosis in leukemia cells through ROS-mitochondria pathway activation

The potential role of extracellular regulatory kinase in the survival of patients with early stage adenocarcinoma