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(3-Chloroacetyl)-indole, a novel allosteric AKT inhibitor, suppresses colon cancer growth in vitro and in vivo.

artículo científico publicado en 2011

3'-Half of the thrombopoietin cDNA confers higher expression of erythropoietin at the RNA level but not at the protein level

artículo científico publicado en 2005

6-Shogaol, an active ingredient of ginger, inhibits osteoclastogenesis and alveolar bone resorption in ligature-induced periodontitis in mice

scientific article published on 01 November 2019

Anti-growth Effects of Imatinib and GNF5 via Regulation of Skp2 in Human Hepatocellular Carcinoma Cells

artículo científico publicado en 2018

Anti-inflammatory effects of a methanol extract of Dictamnus dasycarpus Turcz. root bark on imiquimod-induced psoriasis

scientific article published on 02 December 2019

Beneficial effects of 6-shogaol on hyperglycemia, islet morphology and apoptosis in some tissues of streptozotocin-induced diabetic mice

Bortezomib prevents ovariectomy-induced osteoporosis in mice by inhibiting osteoclast differentiation.

artículo científico publicado en 2017

Cathepsin A regulates pluripotency, proliferation and differentiation in mouse embryonic stem cells

artículo científico publicado en 2020

Ceftriaxone, an FDA-approved cephalosporin antibiotic, suppresses lung cancer growth by targeting Aurora B ⬇️

artículo científico publicado el 7 de septiembre de 2012

Characterization of a brain tumor cell line established from transgenic mice expressing the vasopressin SV-40 T antigen

artículo científico publicado en 2006

Critical role of Rgs19 in mouse embryonic stem cell proliferation and differentiation

artículo científico publicado en 2015

Critical roles of hMAGEA2 in induced pluripotent stem cell pluripotency, proliferation, and differentiation

artículo científico publicado en 2017

DMBA/TPA-induced tumor formation is aggravated in human papillomavirus type 16 E6/E7 transgenic mouse skin

artículo científico publicado en 2007

Direct targeting of MEK1/2 and RSK2 by silybin induces cell-cycle arrest and inhibits melanoma cell growth.

artículo científico publicado en 2013

ERK1 and ERK2 regulate embryonic stem cell self-renewal through phosphorylation of Klf4.

artículo científico publicado en 2012

ERK1 phosphorylates Nanog to regulate protein stability and stem cell self-renewal

scientific article published on 13 April 2014

Ectopic expression of tethered human follicle-stimulating hormone (hFSH) gene in transgenic mice

artículo científico publicado en 2006

Ectopic expression of tmie transgene induces various recovery levels of behavior and hearing ability in the circling mouse

artículo científico publicado en 2008

Effect of conditioned medium of mouse embryonic fibroblasts produced from EC-SOD transgenic mice in nuclear maturation of canine oocytes in vitro

artículo científico publicado en 2006

Effects of Dimethyl Sulfoxide on the Pluripotency and Differentiation Capacity of Mouse Embryonic Stem Cells

scientific article published on 16 September 2020

Effects of regulator of G protein signaling 19 (RGS19) on heart development and function

artículo científico publicado en 2010

Embryonic stem‐cell‐preconditioned microenvironment induces loss of cancer cell properties in human melanoma cells ⬇️

artículo científico publicado el 16 de agosto de 2011

Enforced Expression of Roquin Protein in T Cells Exacerbates the Incidence and Severity of Experimental Arthritis ⬇️

artículo científico publicado el 12 de octubre de 2012

Erratum: Anti-growth Effects of Imatinib and GNF5 via Regulation of Skp2 in Human Hepatocellular Carcinoma Cells

scholarly article published in Journal of cancer prevention

Feeder Independent Culture of Mouse Embryonic Stem Cells

artículo científico publicado en 2012

Genetic ablation of caspase-7 promotes solar-simulated light-induced mouse skin carcinogenesis: the involvement of keratin-17

artículo científico publicado en 2015

Gestational loss and growth restriction by angiogenic defects in placental growth factor transgenic mice

artículo científico publicado en 2014

Ginger-derived compounds exert <i>in vivo</i> and <i>in vitro</i> anti-asthmatic effects by inhibiting the T-helper 2 cell-mediated allergic response

artículo científico publicado en 2021

Hepatic serum amyloid A1 aggravates T cell-mediated hepatitis by inducing chemokines via Toll-like receptor 2 in mice

artículo científico publicado en 2015

Hepatic serum amyloid A1 upregulates interleukin-17 (IL-17) in γδ T cells through Toll-like receptor 2 and is associated with psoriatic symptoms in transgenic mice

scientific article published on 04 April 2019

Herbacetin Is a Novel Allosteric Inhibitor of Ornithine Decarboxylase with Antitumor Activity.

artículo científico publicado en 2015

Herbacetin suppresses cutaneous squamous cell carcinoma and melanoma cell growth by targeting AKT and ODC.

artículo científico publicado en 2017

Human erythropoietin induces lung failure and erythrocytosis in transgenic mice

artículo científico publicado en 2007

Human keratin 14 driven HPV 16 E6/E7 transgenic mice exhibit hyperkeratinosis

artículo científico publicado en 2004

Imatinib and GNF-5 Exhibit an Inhibitory Effect on Growth of Hepatocellar Carcinoma Cells by Downregulating S-phase Kinase-associated Protein 2

scientific article published on 01 December 2020

Inhalation of ammonium sulfate and ammonium nitrate adversely affect sperm function

scientific article published on 29 August 2020

Inhibition of MAGEA2 regulates pluripotency, proliferation, apoptosis, and differentiation in mouse embryonic stem cells

artículo científico publicado en 2020

Inhibition of Migration and Invasion by Tet-1 Overexpression in Human Lung Carcinoma H460 Cells

artículo científico publicado en 2016

Jazf1 promotes prostate cancer progression by activating JNK/Slug

artículo científico publicado en 2017

Kaempferol targets RSK2 and MSK1 to suppress UV radiation-induced skin cancer

artículo científico publicado en 2014

Lin28a expression protects against streptozotocin-induced β-cell destruction and prevents diabetes in mice

artículo científico publicado en 2019

Naringenin targets ERK2 and suppresses UVB-induced photoaging

artículo científico publicado en 2016

Neoplastic transformation and tumorigenesis associated with overexpression of IMUP-1 and IMUP-2 genes in cultured NIH/3T3 mouse fibroblasts

artículo científico publicado en 2006

Norathyriol Suppresses Skin Cancers Induced by Solar Ultraviolet Radiation by Targeting ERK Kinases

artículo científico publicado en 2012

Novel TOPK inhibitor HI-TOPK-032 effectively suppresses colon cancer growth

artículo científico publicado en 2012

Over-expression of Roquin aggravates T cell mediated hepatitis in transgenic mice using T cell specific promoter

artículo científico publicado en 2014

Over-expression of extracellular superoxide dismutase in mouse synovial tissue attenuates the inflammatory arthritis

artículo científico publicado en 2012

Overexpression of Cathepsin S Induces Chronic Atopic Dermatitis in Mice ⬇️

artículo científico publicado el 15 de diciembre de 2011

Overexpression of Jazf1 induces cardiac malformation through the upregulation of pro-apoptotic genes in mice ⬇️

artículo científico publicado el 9 de enero de 2011

Overexpression of Jazf1 reduces body weight gain and regulates lipid metabolism in high fat diet

artículo científico publicado en 2013

Overexpression of extracellular superoxide dismutase (EC-SOD) in mouse skin plays a protective role in DMBA/TPA-induced tumor formation

artículo científico publicado en 2005

PRPF4 is a novel therapeutic target for the treatment of breast cancer by influencing growth, migration, invasion, and apoptosis of breast cancer cells via p38 MAPK signaling pathway

scientific article published on 22 August 2019

Phosphorylation of Sox2 Cooperates in Reprogramming to Pluripotent Stem Cells ⬇️

artículo científico publicado el 1 de diciembre de 2010

Placental growth factor (PlGF) is linked to inflammation and metabolic disorders in mice with diet-induced obesity

artículo científico publicado en 2018

Proteome analysis of developing mice diastema region ⬇️

artículo científico publicado el 1 de junio de 2012

Serine 347 Phosphorylation by JNKs Negatively Regulates OCT4 Protein Stability in Mouse Embryonic Stem Cells

artículo científico publicado en 2017

Serum amyloid A1 is involved in amyloid plaque aggregation and memory decline in amyloid beta abundant condition

artículo científico publicado en 2019

Serum amyloid A1 levels and amyloid deposition following a high-fat diet challenge in transgenic mice overexpressing hepatic serum amyloid A1.

artículo científico publicado en 2016

Spatiotemporal expression of tmie in the inner ear of rats during postnatal development ⬇️

artículo científico publicado el 1 de agosto de 2010

Statistical effect analysis on the testosterone concentration, carcass grade and ultrasonic measurement at 30-month-old of Hanwoo steers

artículo científico publicado en 2018

Suppression of PRPF4 regulates pluripotency, proliferation, and differentiation in mouse embryonic stem cells

scientific article published on 10 September 2019

Suppression of cathepsin a inhibits growth, migration, and invasion by inhibiting the p38 MAPK signaling pathway in prostate cancer

artículo científico publicado en 2020

Suppression of transient receptor potential melastatin 7 regulates pluripotency, proliferation, and differentiation of mouse embryonic stem cells via mechanistic target of rapamycin‐extracellular signal‐regulated kinase activation

scientific article published in 2021

T-LAK cell-originated protein kinase (TOPK) phosphorylation of MKP1 protein prevents solar ultraviolet light-induced inflammation through inhibition of the p38 protein signaling pathway

scientific journal article

TET1 contributes to neurogenesis onset time during fetal brain development in mice

artículo científico publicado en 2016

TRPV1-antagonist AMG9810 promotes mouse skin tumorigenesis through EGFR/Akt signaling ⬇️

artículo científico publicado el 23 de febrero de 2011

Taxifolin Suppresses UV-Induced Skin Carcinogenesis by Targeting EGFR and PI3K ⬇️

artículo científico publicado el 17 de julio de 2012

Tet1 overexpression leads to anxiety-like behavior and enhanced fear memories via the activation of calcium-dependent cascade through Egr1 expression in mice

artículo científico publicado en 2017

The Evolutionarily Conserved LIM Homeodomain Protein LIM-4/LHX6 Specifies the Terminal Identity of a Cholinergic and Peptidergic C. elegans Sensory/Inter/Motor Neuron-Type

artículo científico publicado en 2015

The parthenogenetic activation of canine oocytes with Ca-EDTA by various culture periods and concentrations

artículo científico publicado en 2006

The role of Roquin overexpression in the modulation of signaling during in vitro and ex vivo T-cell activation ⬇️

artículo científico publicado el 29 de noviembre de 2011

The therapeutic effect of extracellular superoxide dismutase (EC-SOD) mouse embryonic fibroblast (MEF) on collagen-induced arthritis (CIA) mice

artículo científico publicado en 2008

Tissue-Specific Expression of Human Calcineurin-Binding Protein 1 in Mouse Synovial Tissue Can Suppress Inflammatory Arthritis ⬇️

artículo científico publicado el 16 de diciembre de 2011

Transgene expression of biological active recombinant human granulocyte-colony stimulating factor (hG-CSF) into mouse urine

artículo científico publicado en 2005

Tumor suppressor p16 inhibits cancer cell growth by downregulating eEF1A2 through a direct interaction

artículo científico publicado en 2013

Tumor suppressor p16(INK4a) inhibits cancer cell growth by downregulating eEF1A2 through a direct interaction.

artículo científico publicado en 2013

Vanadium adversely affects sperm motility and capacitation status via protein kinase A activity and tyrosine phosphorylation

artículo científico publicado en 2020

Vasopressin-SV40 T antigen expression in transgenic mice induces brain tumor and lymphoma

artículo científico publicado en 2003

ZNF507 affects TGF-β signaling via TGFBR1 and MAP3K8 activation in the progression of prostate cancer to an aggressive state

artículo científico publicado en 2021

[6]-shogaol inhibits growth and induces apoptosis of non-small cell lung cancer cells by directly regulating Akt1/2.

artículo científico publicado en 2013

hMAGEA2 promotes progression of breast cancer by regulating Akt and Erk1/2 pathways

artículo científico publicado en 2017

tmie Is required for gentamicin uptake by the hair cells of mice

artículo científico publicado en 2013

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