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A Next-Generation TRK Kinase Inhibitor Overcomes Acquired Resistance to Prior TRK Kinase Inhibition in Patients with TRK Fusion-Positive Solid Tumors

artículo científico publicado en 2017

A Performance Comparison of Commonly Used Assays to Detect RET Fusions

artículo científico publicado en 2020

A Phase I/Ib Trial of the VEGFR-Sparing Multikinase RET Inhibitor RXDX-105

scientific article published on 28 November 2018

A Phase Ib/II Study of Ramucirumab in Combination with Emibetuzumab in Patients with Advanced Cancer

artículo científico publicado en 2019

Activating mutations in CSF1R and additional receptor tyrosine kinases in histiocytic neoplasms

scientific article published on 25 November 2019

Antitumor activity of crizotinib in lung cancers harboring a MET exon 14 alteration

artículo científico publicado en 2020

Colorectal Carcinomas Containing Hypermethylated MLH1 Promoter and Wild-Type BRAF/KRAS Are Enriched for Targetable Kinase Fusions

scientific article published on 14 January 2019

Comprehensive Molecular and Clinicopathologic Analysis of 200 Pulmonary Invasive Mucinous Adenocarcinomas Identifies Distinct Characteristics of Molecular Subtypes

artículo científico publicado en 2021

Efficacy of Larotrectinib in TRK Fusion-Positive Cancers in Adults and Children.

artículo científico publicado en 2018

High Yield of RNA Sequencing for Targetable Kinase Fusions in Lung Adenocarcinomas with No Mitogenic Driver Alteration Detected by DNA Sequencing and Low Tumor Mutation Burden

scientific article published on 26 April 2019

Immunogenicity and therapeutic targeting of a public neoantigen derived from mutated PIK3CA

artículo científico publicado en 2022

MAPK pathway alterations correlate with poor survival and drive resistance to therapy in patients with lung cancers driven by ROS1 fusions

artículo científico publicado en 2020

MET exon 14-altered lung cancers and MET inhibitor resistance

artículo científico publicado en 2020

MET-dependent solid tumours - molecular diagnosis and targeted therapy

artículo científico publicado en 2020

NTRK fusion detection across multiple assays and 33,997 cases: diagnostic implications and pitfalls

artículo científico publicado en 2019

NTRK fusion-positive cancers and TRK inhibitor therapy

artículo científico publicado en 2018

Overcoming MET-dependent resistance to selective RET inhibition in patients with RET fusion-positive lung cancer by combining selpercatinib with crizotinib

artículo científico publicado en 2020

Progresses toward precision medicine in RET-altered solid tumors

artículo científico publicado en 2020

ROS1-dependent cancers - biology, diagnostics and therapeutics

artículo científico publicado en 2020

Repotrectinib Exhibits Potent Antitumor Activity in Treatment-Naïve and Solvent-Front-Mutant ROS1-Rearranged Non-Small Cell Lung Cancer

artículo científico publicado en 2020

Resistance to TRK inhibition mediated by convergent MAPK pathway activation

scientific article published on 12 August 2019

TRK Fusions Are Enriched in Cancers with Uncommon Histologies and the Absence of Canonical Driver Mutations

artículo científico publicado en 2019

TRK xDFG mutations trigger a sensitivity switch from type I to II kinase inhibitors

scientific article published on 01 October 2020

The METeoric rise of MET in lung cancer

artículo científico publicado en 2020

The evolution of RET inhibitor resistance in RET-driven lung and thyroid cancers

artículo científico publicado en 2022

Therapeutic Implications of Germline Testing in Patients With Advanced Cancers

artículo científico publicado en 2021

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