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A novel class of negative allosteric modulators of NMDA receptor function

artículo científico publicado en 2015

A subunit-selective potentiator of NR2C- and NR2D-containing NMDA receptors.

artículo científico publicado en 2010

Biased modulators of NMDA receptors control channel opening and ion selectivity

scientific article published on 20 January 2020

Context-dependent GluN2B-selective inhibitors of NMDA receptor function are neuroprotective with minimal side effects

artículo científico publicado en 2015

De novo GRIN variants in NMDA receptor M2 channel pore-forming loop are associated with neurological diseases

artículo científico publicado en 2019

Distinct roles of GRIN2A and GRIN2B variants in neurological conditions

scientific article published on 20 November 2019

Enantiomeric propanolamines as selective N-methyl-D-aspartate 2B receptor antagonists.

artículo científico publicado en 2008

Hodgkin-huxley-katz prize lecture: genetic and pharmacological control of glutamate receptor channel through a highly conserved gating motif

artículo científico publicado en 2020

Mapping the binding of GluN2B-selective N-methyl-D-aspartate receptor negative allosteric modulators

artículo científico publicado en 2012

Mechanism for noncompetitive inhibition by novel GluN2C/D N-methyl-D-aspartate receptor subunit-selective modulators

artículo científico publicado en 2011

Molecular Mechanism of Disease-Associated Mutations in the Pre-M1 Helix of NMDA Receptors and Potential Rescue Pharmacology.

artículo científico publicado en 2017

Negative allosteric modulation of GluN1/GluN3 NMDA receptors

scientific article published on 07 May 2020

Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors

artículo científico publicado en 2019

Synthesis, structural activity-relationships, and biological evaluation of novel amide-based allosteric binding site antagonists in NR1A/NR2B N-methyl-D-aspartate receptors

artículo científico publicado en 2009

The GRIA3 c.2477G > A Variant Causes an Exaggerated Startle Reflex, Chorea, and Multifocal Myoclonus

scientific article published on 05 May 2020

The GluN2B-Glu413Gly NMDA receptor variant arising from a de novo GRIN2B mutation promotes ligand-unbinding and domain opening

artículo científico publicado en 2018