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Lista de obras de Jaroslaw P. Maciejewski

A Phase 2 study of combination therapy with arsenic trioxide and gemtuzumab ozogamicin in patients with myelodysplastic syndromes or secondary acute myeloid leukemia

artículo científico publicado el 19 de octubre de 2010

A phase II multicenter rabbit anti-thymocyte globulin trial in patients with myelodysplastic syndromes identifying a novel model for response prediction.

artículo científico publicado en 2014

A pilot study of the recombinant soluble human tumour necrosis factor receptor (p75)-Fc fusion protein in patients with myelodysplastic syndrome

scientific article published on 01 April 2002

A severe and consistent deficit in marrow and circulating primitive hematopoietic cells (long-term culture-initiating cells) in acquired aplastic anemia

artículo científico publicado en 1996

Acquired amegakaryocytic thrombocytopenia and pure red cell aplasia associated with an occult large granular lymphocyte leukemia

artículo científico publicado en 2007

Activation of the mTOR signaling pathway by L-leucine in 5q- syndrome and other RPS14-deficient erythroblasts

artículo científico publicado en 2013

Adding molecular data to prognostic models can improve predictive power in treated patients with myelodysplastic syndromes.

artículo científico publicado en 2017

Alternatively spliced, truncated GCSF receptor promotes leukemogenic properties and sensitivity to JAK inhibition

artículo científico publicado en 2013

An International MDS/MPN Working Group's perspective and recommendations on molecular pathogenesis, diagnosis and clinical characterization of myelodysplastic/myeloproliferative neoplasms.

artículo científico publicado en 2015

An international consortium proposal of uniform response criteria for myelodysplastic/myeloproliferative neoplasms (MDS/MPN) in adults

artículo científico publicado en 2015

Analysis of distinct SF3B1 hotspot mutations in relation to clinical phenotypes and response to therapy in myeloid neoplasia

artículo científico publicado en 2020

Base excision repair dysfunction in a subgroup of patients with myelodysplastic syndrome

artículo científico publicado en 2007

Baseline characteristics and disease burden in patients in the International Paroxysmal Nocturnal Hemoglobinuria Registry

artículo científico publicado en 2014

Bone marrow and peripheral blood lymphocyte phenotype in patients with bone marrow failure

scientific article published on 01 October 1994

CSF3R T618I co-occurs with mutations of splicing and epigenetic genes and with a new PIM3 truncated fusion gene in chronic neutrophilic leukemia

artículo científico publicado en 2013

Chromosomal lesions and uniparental disomy detected by SNP arrays in MDS, MDS/MPD, and MDS-derived AML

artículo científico publicado en 2008

Circulating microbial content in myeloid malignancy patients is associated with disease subtypes and patient outcomes

artículo científico publicado en 2022

Clinical and biological implications of ancestral and non-ancestral IDH1 and IDH2 mutations in myeloid neoplasms

artículo científico publicado en 2015

Clinicopathologic and molecular characterization of myeloid neoplasms with isolated t(6;9)(p23;q34).

artículo científico publicado en 2017

Clonal PIGA mosaicism and dynamics in paroxysmal nocturnal hemoglobinuria

artículo científico publicado en 2018

Comparison of risk stratification tools in predicting outcomes of patients with higher-risk myelodysplastic syndromes treated with azanucleosides.

artículo científico publicado en 2015

Comprehensive quantitative proteomic profiling of the pharmacodynamic changes induced by MLN4924 in acute myeloid leukemia cells establishes rationale for its combination with azacitidine

artículo científico publicado en 2015

Connect MDS/AML: design of the myelodysplastic syndromes and acute myeloid leukemia disease registry, a prospective observational cohort study

artículo científico publicado en 2016

Context dependent effects of ascorbic acid treatment in TET2 mutant myeloid neoplasia

artículo científico publicado en 2020

Copy neutral loss of heterozygosity: a novel chromosomal lesion in myeloid malignancies

artículo científico publicado en 2010

Cx25 contributes to leukemia cell communication and chemosensitivity.

artículo científico publicado en 2015

Cytokine signature profiles in acquired aplastic anemia and myelodysplastic syndromes.

artículo científico publicado en 2010

Cytomegalovirus-specific regulatory and effector T cells share TCR clonality--possible relation to repetitive CMV infections

artículo científico publicado en 2011

Cytopenia levels for aiding establishment of the diagnosis of myelodysplastic syndromes

artículo científico publicado en 2016

Deep sequencing reveals stepwise mutation acquisition in paroxysmal nocturnal hemoglobinuria.

artículo científico publicado en 2014

Defects in spliceosomal machinery: a new pathway of leukaemogenesis

artículo científico publicado en 2012

Defining AML and MDS second cancer risk dynamics after diagnoses of first cancers treated or not with radiation

artículo científico publicado en 2015

Deletion of Ptpn1 induces myeloproliferative neoplasm.

artículo científico publicado en 2017

Deletions of Xp22.2 including PIG-A locus lead to paroxysmal nocturnal hemoglobinuria

artículo científico publicado en 2010

Dexrazoxane enhances efficacy of all-trans retinoic acid in acute myeloid leukemia patient blast cells and cell lines

artículo científico publicado en 2020

Differential gene expression in hematopoietic progenitors from paroxysmal nocturnal hemoglobinuria patients reveals an apoptosis/immune response in 'normal' phenotype cells

artículo científico publicado en 2005

Differing clinical features between Japanese and Caucasian patients with myelodysplastic syndromes: Analysis from the International Working Group for Prognosis of MDS

scientific article published on 06 September 2018

Discrimination of T-cell subsets and T-cell receptor repertoire distribution.

artículo científico publicado en 2014

Disruption of SF3B1 results in deregulated expression and splicing of key genes and pathways in myelodysplastic syndrome hematopoietic stem and progenitor cells

artículo científico publicado en 2014

Disruption of SF3B1 results in deregulated expression and splicing of key genes and pathways in myelodysplastic syndrome hematopoietic stem and progenitor cells

artículo científico publicado en 2015

Distinctive and common features of moderate aplastic anaemia

scientific article published on 31 January 2020

Dose-dependent role of the cohesin complex in normal and malignant hematopoiesis

artículo científico publicado en 2015

Double-negative regulatory T cells induce allotolerance when expanded after allogeneic haematopoietic stem cell transplantation

artículo científico publicado en 2008

Dynamics of clonal evolution in myelodysplastic syndromes

artículo científico publicado en 2016

Effects of cyclosporine on hematopoietic and immune functions in patients with hypoplastic myelodysplasia: in vitro and in vivo studies

artículo científico publicado en 2002

Emerging roles of the spliceosomal machinery in myelodysplastic syndromes and other hematological disorders

artículo científico

Epidemiology and risk factors for infections in myelodysplastic syndromes

artículo científico publicado en 2013

Expression of stem cell inhibitor (SCI) gene in patients with bone marrow failure

artículo científico publicado el 1 de octubre de 1992

FISH and SNP-A karyotyping in myelodysplastic syndromes: improving cytogenetic detection of del(5q), monosomy 7, del(7q), trisomy 8 and del(20q)

artículo científico publicado en 2010

Fas antigen expression on CD34+ human marrow cells is induced by interferon gamma and tumor necrosis factor alpha and potentiates cytokine-mediated hematopoietic suppression in vitro

scientific article published on 01 June 1995

From Bench to Bedside and Beyond: Therapeutic Scenario in Acute Myeloid Leukemia

artículo científico publicado en 2020

Function and malfunction of hematopoietic stem cells in primary bone marrow failure syndromes

scientific article published on January 2007

Genetic abnormalities in myelodysplasia and secondary acute myeloid leukemia: impact on outcome of stem cell transplantation

artículo científico publicado en 2017

Genetic alterations of the cohesin complex genes in myeloid malignancies.

artículo científico publicado en 2014

Genomic determinants of chronic myelomonocytic leukemia

artículo científico publicado en 2017

Genomics of therapy-related myeloid neoplasms

scientific article published on 14 August 2019

High prevalence and allele burden-independent prognostic importance of p53 mutations in an inner-city MDS/AML cohort.

artículo científico publicado en 2016

Human cytomegalovirus persists in myeloid progenitors and is passed to the myeloid progeny in a latent form

artículo científico publicado en 2004

Hypocupremia and bone marrow failure

artículo científico publicado en 2008

Impact of immunogenetic polymorphisms in bone marrow failure syndromes

artículo científico publicado en 2011

Impact of molecular mutations on treatment response to DNMT inhibitors in myelodysplasia and related neoplasms

artículo científico publicado en 2013

Impact of weekend admissions on quality of care and outcomes in patients with acute myeloid leukemia

artículo científico publicado en 2010

Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2

artículo científico publicado en 2010

Incorporation of molecular data into the Revised International Prognostic Scoring System in treated patients with myelodysplastic syndromes

artículo científico publicado en 2016

Increased frequency of HLA-DR2 in patients with paroxysmal nocturnal hemoglobinuria and the PNH/aplastic anemia syndrome

artículo científico publicado en 2001

Infection of hematopoietic progenitor cells by human cytomegalovirus

artículo científico publicado el 1 de julio de 1992

Influence of killer immunoglobulin-like receptor/HLA ligand matching on achievement of T-cell complete donor chimerism in related donor nonmyeloablative allogeneic hematopoietic stem cell transplantation

artículo científico publicado en 2008

Inherited and Somatic Defects in DDX41 in Myeloid Neoplasms

scientific journal article

Invariant patterns of clonal succession determine specific clinical features of myelodysplastic syndromes

scientific article published on 26 November 2019

Large granular lymphocyte (LGL)-like clonal expansions in paroxysmal nocturnal hemoglobinuria (PNH) patients.

artículo científico publicado en 2005

Late complications following treatment for severe aplastic anemia (SAA) with high-dose cyclophosphamide (Cy): follow-up of a randomized trial

artículo científico publicado en 2002

Long-lasting decrease of marrow and circulating long-term culture initiating cells after allogeneic bone marrow transplant

scientific article published on 01 May 1999

Long-term follow-up of patients with moderate aplastic anemia and pure red cell aplasia treated with daclizumab

artículo científico publicado en 2010

Loss of heterozygosity in 7q myeloid disorders: clinical associations and genomic pathogenesis

artículo científico publicado en 2012

MICA polymorphism identified by whole genome array associated with NKG2D-mediated cytotoxicity in T-cell large granular lymphocyte leukemia

artículo científico publicado en 2010

Measurement of secondary colony formation after 5 weeks in long-term cultures in patients with myelodysplastic syndrome

artículo científico publicado el 1 de agosto de 1998

Methylome profiling reveals distinct alterations in phenotypic and mutational subgroups of myeloproliferative neoplasms

artículo científico publicado en 2012

Molecular and clinical analyses of PHF6 mutant myeloid neoplasia provide their pathogenesis and therapeutic targeting

artículo científico publicado en 2024

Molecular features of early onset adult myelodysplastic syndrome

artículo científico publicado en 2017

Molecular pathogenesis of disease progression in MLL-rearranged AML

artículo científico publicado en 2018

Multicenter phase 3 study of the complement inhibitor eculizumab for the treatment of patients with paroxysmal nocturnal hemoglobinuria

artículo científico publicado en 2007

Multiple mechanisms deregulate EZH2 and histone H3 lysine 27 epigenetic changes in myeloid malignancies.

artículo científico publicado en 2013

Mutational landscape of myelodysplastic/myeloproliferative neoplasm-unclassifiable

artículo científico publicado en 2018

Mutations in G protein β subunits promote transformation and kinase inhibitor resistance

artículo científico publicado en 2014

Mutations of an E3 ubiquitin ligase c-Cbl but not TET2 mutations are pathogenic in juvenile myelomonocytic leukemia

artículo científico publicado en 2009

Mutations of e3 ubiquitin ligase cbl family members constitute a novel common pathogenic lesion in myeloid malignancies.

artículo científico publicado en 2009

Myeloid malignancies with chromosome 5q deletions acquire a dependency on an intrachromosomal NF-κB gene network

artículo científico publicado en 2014

Nitric oxide suppression of human hematopoiesis in vitro. Contribution to inhibitory action of interferon-gamma and tumor necrosis factor-alpha

artículo científico publicado en 1995

Novel homo- and hemizygous mutations in EZH2 in myeloid malignancies

artículo científico publicado en 2010

Novel invariant features of Good syndrome

artículo científico publicado en 2021

Novel recurrent mutations in the RAS-like GTP-binding gene RIT1 in myeloid malignancies.

artículo científico publicado en 2013

Optimization of therapy for severe aplastic anemia based on clinical, biologic, and treatment response parameters: conclusions of an international working group on severe aplastic anemia convened by the Blood and Marrow Transplant Clinical Trials Ne

artículo científico publicado en 2010

Outcomes of patients with myelodysplastic syndromes who achieve stable disease after treatment with hypomethylating agents

scientific article published on 22 December 2015

Paroxysmal nocturnal hemoglobinuria and concurrent JAK2(V617F) mutation.

artículo científico publicado en 2012

Phase I combination trial of lenalidomide and azacitidine in patients with higher-risk myelodysplastic syndromes

artículo científico publicado en 2010

Predictive factors of response and survival among chronic myelomonocytic leukemia patients treated with azacitidine

artículo científico publicado en 2013

Prognostic signature and clonality pattern of recurrently mutated genes in inactive chronic lymphocytic leukemia

artículo científico publicado en 2015

Radioprotection of IDH1-Mutated Cancer Cells by the IDH1-Mutant Inhibitor AGI-5198.

artículo científico publicado en 2015

Real-world diagnostic testing patterns for assessment of ring sideroblasts and SF3B1 mutations in patients with newly diagnosed lower-risk myelodysplastic syndromes

artículo científico publicado en 2020

Recurrent genetic defects on chromosome 7q in myeloid neoplasms

artículo científico publicado en 2014

Relationship between bone marrow failure syndromes and the presence of glycophosphatidyl inositol-anchored protein-deficient clones

scientific article published on 01 December 2001

Relationship of treatment-related cytopenias and response to lenalidomide in patients with lower-risk myelodysplastic syndromes

artículo científico publicado en 2008

Reply to A. Piccardo et al, E. Hindié et al, M.C. Kreissl et al, M. Doss, J. Buscombe, R. Fisher, M. Sollini et al, M. Lichtenstein, and M. Tulchinsky et al

artículo científico publicado en 2018

Revised international prognostic scoring system for myelodysplastic syndromes

artículo científico publicado en 2012

Risk of Hematologic Malignancies After Radioiodine Treatment of Well-Differentiated Thyroid Cancer

artículo científico publicado en 2017

Risk of developing chronic myeloid neoplasms in well-differentiated thyroid cancer patients treated with radioactive iodine.

artículo científico publicado en 2017

Role of Fas ligand and receptor in the mechanism of T-cell depletion in acquired immunodeficiency syndrome: effect on CD4+ lymphocyte depletion and human immunodeficiency virus replication.

artículo científico publicado en 1997

SF3B1, a splicing factor is frequently mutated in refractory anemia with ring sideroblasts

scientific article published on 02 September 2011

SF3B1-mutant myelodysplastic syndrome as a distinct disease subtype - A Proposal of the International Working Group for the Prognosis of Myelodysplastic Syndromes (IWG-PM)

artículo científico publicado en 2020

SNP array karyotyping allows for the detection of uniparental disomy and cryptic chromosomal abnormalities in MDS/MPD-U and MPD.

artículo científico publicado en 2007

STAT3 mutations indicate the presence of subclinical T-cell clones in a subset of aplastic anemia and myelodysplastic syndrome patients

artículo científico publicado en 2013

Single nucleotide polymorphism array lesions, TET2, DNMT3A, ASXL1 and CBL mutations are present in systemic mastocytosis.

artículo científico publicado en 2012

Single nucleotide polymorphism arrays complement metaphase cytogenetics in detection of new chromosomal lesions in MDS.

artículo científico publicado en 2007

Somatic STAT3 mutations in large granular lymphocytic leukemia

artículo científico publicado en 2012

Spread of human cytomegalovirus (HCMV) after infection of human hematopoietic progenitor cells: model of HCMV latency

artículo científico publicado el 15 de septiembre de 1997

Stem and progenitor cells in myelodysplastic syndromes show aberrant stage-specific expansion and harbor genetic and epigenetic alterations

artículo científico publicado en 2012

Survival of AML patients receiving HLA-matched sibling donor allogeneic bone marrow transplantation correlates with HLA-Cw ligand groups for killer immunoglobulin-like receptors

scientific article published on 19 February 2007

Sustained long-term hematologic recovery despite a marked quantitative defect in the stem cell compartment of patients with aplastic anemia after immunosuppressive therapy

artículo científico publicado en 2000

TP53 mutation status divides myelodysplastic syndromes with complex karyotypes into distinct prognostic subgroups

scientific article published on 11 January 2019

Telomere length in leukocyte subpopulations of patients with aplastic anemia

scientific article published on 01 February 2001

Tet2 loss leads to hypermutagenicity in haematopoietic stem/progenitor cells

artículo científico publicado en 2017

The analysis of clonal diversity and therapy responses using STAT3 mutations as a molecular marker in large granular lymphocytic leukemia

artículo científico publicado en 2014

The complement inhibitor eculizumab in paroxysmal nocturnal hemoglobinuria

artículo científico publicado en 2006

The complexity of interpreting genomic data in patients with acute myeloid leukemia

artículo científico publicado en 2016

The driver and passenger effects of isocitrate dehydrogenase 1 and 2 mutations in oncogenesis and survival prolongation

artículo científico publicado en 2014

The efficacy of current prognostic models in predicting outcome of patients with myelodysplastic syndromes at the time of hypomethylating agent failure

artículo científico publicado en 2016

The relationship of TP53 R72P polymorphism to disease outcome and TP53 mutation in myelodysplastic syndromes

artículo científico publicado en 2015

The role of FAS-mediated apoptosis in chronic myelogenous leukemia

artículo científico publicado en 2000

The role of interleukin-converting enzyme in Fas-mediated apoptosis in HIV-1 infection

artículo científico publicado el 1 de enero de 1998

Therapeutic implications of variable expression of CD52 on clonal cytotoxic T cells in CD8+ large granular lymphocyte leukemia

artículo científico publicado en 2009

Time-dependent changes in mortality and transformation risk in MDS.

artículo científico publicado en 2016

Tofacitinib as a novel salvage therapy for refractory T-cell large granular lymphocytic leukemia.

artículo científico publicado en 2015

Treatment outcomes for patients with myelodysplastic syndrome/myeloproliferative neoplasms with ring sideroblasts and thrombocytosis

artículo científico publicado en 2021

UPD1p indicates the presence of MPL W515L mutation in RARS-T, a mechanism analogous to UPD9p and JAK2 V617F mutation

artículo científico publicado en 2008

Ubiquitination of hnRNPA1 by TRAF6 links chronic innate immune signaling with myelodysplasia.

artículo científico publicado en 2016

mutations define a specific subgroup of MDS and MDS/MPN patients with favorable outcomes with intensive chemotherapy