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'MRI-tis' in the early diagnosis of axial SpA: issues and limitations

scientific article published on 05 October 2010

14-3-3η is a novel mediator associated with the pathogenesis of rheumatoid arthritis and joint damage

artículo científico publicado en 2014

2010 Rheumatoid arthritis classification criteria: An American College of Rheumatology/European League Against Rheumatism collaborative initiative

scholarly article by Daniel Aletaha et al published 10 August 2010 in Arthritis and Rheumatism

2010 rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative

artículo científico publicado en 2010

A Prospective, Randomized, Placebo-Controlled Study to Identify Biomarkers Associated with Active Treatment in Psoriatic Arthritis: Effects of Adalimumab Treatment on Lesional and Nonlesional Skin

artículo científico publicado el 21 de diciembre de 2012

A Rac1 inhibitory peptide suppresses antibody production and paw swelling in the murine collagen-induced arthritis model of rheumatoid arthritis

artículo científico publicado en 2010

A clinically based protein discovery strategy to identify potential biomarkers of response to anti-TNF-α treatment of psoriatic arthritis

artículo científico publicado en 2015

A novel approach for gene therapy: engraftment of fibroblasts containing the artificial chromosome expression system at the site of inflammation

artículo científico publicado en 2006

A novel spleen tyrosine kinase inhibitor blocks c-Jun N-terminal kinase-mediated gene expression in synoviocytes.

artículo científico publicado en 2006

A randomized controlled trial with an anti-CCL2 (anti-monocyte chemotactic protein 1) monoclonal antibody in patients with rheumatoid arthritis

artículo científico publicado en 2006

Absence of a classically activated macrophage cytokine signature in peripheral spondylarthritis, including psoriatic arthritis

artículo científico publicado en 2009

Absence of changes in the number of synovial sublining macrophages after ineffective treatment for rheumatoid arthritis: Implications for use of synovial sublining macrophages as a biomarker

artículo científico publicado en 2007

Activated complement components and complement activator molecules on the surface of cell-derived microparticles in patients with rheumatoid arthritis and healthy individuals

artículo científico publicado en 2007

Adding tocilizumab or switching to tocilizumab monotherapy in methotrexate inadequate responders: 24-week symptomatic and structural results of a 2-year randomised controlled strategy trial in rheumatoid arthritis (ACT-RAY)

artículo científico publicado en 2013

Adeno-associated virus type 5-mediated intraarticular administration of tumor necrosis factor small interfering RNA improves collagen-induced arthritis.

artículo científico publicado en 2010

Adherence to Treat-to-target Management in Rheumatoid Arthritis and Associated Factors: Data from the International RA BIODAM Cohort

scientific article published on 15 September 2019

Advancements in adeno-associated viral gene therapy approaches: exploring a new horizon

artículo científico publicado el 1 de enero de 2011

Alefacept therapy reduces the effector T-cell population in lesional psoriatic epidermis

artículo científico publicado en 2004

Alefacept treatment in psoriatic arthritis: reduction of the effector T cell population in peripheral blood and synovial tissue is associated with improvement of clinical signs of arthritis

artículo científico publicado en 2002

Altered expression of microRNA-203 in rheumatoid arthritis synovial fibroblasts and its role in fibroblast activation.

artículo científico publicado en 2011

Amelioration of arthritis by intraarticular dominant negative Ikk beta gene therapy using adeno-associated virus type 5.

artículo científico publicado en 2006

Analysis of apoptosis in peripheral blood and synovial tissue very early after initiation of infliximab treatment in rheumatoid arthritis patients

scientific article published on 01 November 2008

Angiopoietin-2 promotes inflammatory activation of human macrophages and is essential for murine experimental arthritis

artículo científico publicado el 22 de junio de 2012

Animal models for arthritis: innovative tools for prevention and treatment

artículo científico publicado en 2011

Anti-TNF therapy reduces serum levels of chemerin in rheumatoid arthritis: a new mechanism by which anti-TNF might reduce inflammation

artículo científico publicado en 2013

Anti-TNF treatment blocks the induction of T cell-dependent humoral responses

artículo científico publicado el 11 de septiembre de 2012

Anti-colony-stimulating factor therapies for inflammatory and autoimmune diseases

artículo científico publicado en 2016

Association of response to TNF inhibitors in rheumatoid arthritis with quantitative trait loci for and CD39

article

B lymphocyte autoimmunity in rheumatoid synovitis is independent of ectopic lymphoid neogenesis

artículo científico publicado en 2008

Biodistribution and radiation dosimetry of 99mTc-HMPAO-labeled monocytes in patients with rheumatoid arthritis

artículo científico publicado en 2008

Body mass index and clinical response to infliximab in rheumatoid arthritis

artículo científico publicado el 1 de febrero de 2011

Brief Report: A phase IIa, randomized, double‐blind, placebo‐controlled trial of apilimod mesylate, an interleukin‐12/interleukin‐23 inhibitor, in patients with rheumatoid arthritis

artículo científico publicado el 14 de diciembre de 2011

Brief Report: Altered Innate Lymphoid Cell Subsets in Human Lymph Node Biopsy Specimens Obtained During the At-Risk and Earliest Phases of Rheumatoid Arthritis.

artículo científico publicado en 2016

Brief Report: The Role of Rare Protein-Coding Variants in Anti-Tumor Necrosis Factor Treatment Response in Rheumatoid Arthritis.

artículo científico publicado en 2016

Btk inhibition suppresses agonist-induced human macrophage activation and inflammatory gene expression in RA synovial tissue explants

artículo científico publicado en 2014

CCR5 blockade in rheumatoid arthritis: a randomised, double-blind, placebo-controlled clinical trial.

artículo científico publicado en 2010

CD55 deposited on synovial collagen fibers protects from immune complex-mediated arthritis

artículo científico publicado en 2015

CD97 in Leukocyte Trafficking

artículo científico publicado el 1 de enero de 2010

CD97 neutralisation increases resistance to collagen-induced arthritis in mice

artículo científico publicado en 2006

Characteristics of synovial inflammation in early arthritis analysed by pixel-by-pixel time-intensity curve shape analysis

artículo científico publicado el 28 de febrero de 2012

Citrullinated proteins in rheumatoid arthritis: crucial...but not sufficient!

artículo científico publicado en 2006

Citrullination of epithelial neutrophil-activating peptide 78/CXCL5 results in conversion from a non-monocyte-recruiting chemokine to a monocyte-recruiting chemokine.

artículo científico publicado en 2014

Collagen-induced arthritis in mice

artículo científico publicado en 2010

Colony-stimulating factor (CSF) 1 receptor blockade reduces inflammation in human and murine models of rheumatoid arthritis

artículo científico publicado en 2016

Common variants at CD40 and other loci confer risk of rheumatoid arthritis

scientific article published on 14 September 2008

Comparative assessment of leflunomide and methotrexate for the treatment of rheumatoid arthritis, by dynamic enhanced magnetic resonance imaging

artículo científico publicado en 2002

Comparison of synovial tissues from the knee joints and the small joints of rheumatoid arthritis patients: Implications for pathogenesis and evaluation of treatment

artículo científico publicado en 2002

Corrigendum: Synovial tissue research: a state-of-the-art review

artículo científico publicado en 2017

Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis

artículo científico publicado en 2016

Deactivation of endothelium and reduction in angiogenesis in psoriatic skin and synovium by low dose infliximab therapy in combination with stable methotrexate therapy: a prospective single-centre study

artículo científico publicado en 2004

Decrease in synovial cellularity and cytokine expression after autologous stem cell transplantation in patients with juvenile idiopathic arthritis

artículo científico publicado en 2002

Deletion of either CD55 or CD97 ameliorates arthritis in mouse models

artículo científico publicado en 2010

Dendritic cell subsets: their roles in rheumatoid arthritis.

artículo científico publicado en 2008

Development of antiinfliximab antibodies and relationship to clinical response in patients with rheumatoid arthritis

artículo científico publicado en 2006

Differential expression of CD97 on human lymphocyte subsets and limited effect of CD97 antibodies on allogeneic T-cell stimulation

artículo científico publicado en 2009

Digital image analysis for the evaluation of the inflammatory infiltrate in psoriasis

artículo científico publicado en 2005

Discovery of Innovative Therapies for Rare Immune-Mediated Inflammatory Diseases via Off-Label Prescription of Biologics: The Case of IL-6 Receptor Blockade in Castleman's Disease

artículo científico publicado en 2015

Disease activity-guided rituximab therapy in rheumatoid arthritis: the effects of re-treatment in initial nonresponders versus initial responders

artículo científico publicado en 2008

Disease-specific and inflammation-independent stromal alterations in spondylarthritis synovitis

artículo científico publicado en 2013

Distinct synovial immunopathologic characteristics of juvenile-onset spondylarthritis and other forms of juvenile idiopathic arthritis

artículo científico publicado en 2006

Distinct synovial immunopathology in Behçet disease and psoriatic arthritis

artículo científico publicado en 2009

Does the multi-biomarker disease activity score have diagnostic value in early rheumatoid arthritis and unclassified arthritis?

artículo científico publicado en 2015

Dominant B cell receptor clones in peripheral blood predict onset of arthritis in individuals at risk for rheumatoid arthritis

artículo científico

Dynamic Contrast-Enhanced Magnetic Resonance Imaging Using Pharmacokinetic Modeling: Initial Experience in Patients With Early Arthritis

artículo científico publicado en 2016

EULAR recommendations for terminology and research in individuals at risk of rheumatoid arthritis: report from the Study Group for Risk Factors for Rheumatoid Arthritis

artículo científico publicado en 2012

Early effects of rituximab on the synovial cell infiltrate in patients with rheumatoid arthritis

artículo científico publicado en 2007

Effect of baseline rheumatoid factor and anticitrullinated peptide antibody serotype on rituximab clinical response: a meta-analysis

artículo científico publicado en 2012

Effects of oral prednisolone on biomarkers in synovial tissue and clinical improvement in rheumatoid arthritis

artículo científico publicado en 2004

Efficacy and safety of adalimumab for the treatment of peripheral arthritis in spondyloarthritis patients without ankylosing spondylitis or psoriatic arthritis

artículo científico publicado el 8 de noviembre de 2012

Efficacy and safety of epratuzumab in patients with moderate/severe flaring systemic lupus erythematosus: results from two randomized, double-blind, placebo-controlled, multicentre studies (ALLEVIATE) and follow-up

artículo científico publicado en 2013

Efficacy and safety of monotherapy with sirukumab compared with adalimumab monotherapy in biologic-naïve patients with active rheumatoid arthritis (SIRROUND-H): a randomised, double-blind, parallel-group, multinational, 52-week, phase 3 study

scientific article published on 26 February 2018

Efficacy and safety of secukinumab, a fully human anti-interleukin-17A monoclonal antibody, in patients with moderate-to-severe psoriatic arthritis: a 24-week, randomised, double-blind, placebo-controlled, phase II proof-of-concept trial

artículo científico publicado en 2013

Efficacy and safety of sirukumab in patients with active rheumatoid arthritis refractory to anti-TNF therapy (SIRROUND-T): a randomised, double-blind, placebo-controlled, parallel-group, multinational, phase 3 study

artículo científico publicado en 2017

Empty Capsids and Macrophage Inhibition/Depletion Increase rAAV Transgene Expression in Joints of Both Healthy and Arthritic Mice

artículo científico publicado en 2016

Enumeration and phenotypical analysis of distinct dendritic cell subsets in psoriatic arthritis and rheumatoid arthritis

artículo científico publicado en 2006

Erratum: Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis

artículo científico publicado en 2016

Evaluating antirheumatic treatments using synovial biopsy: a recommendation for standardisation to be used in clinical trials

artículo científico publicado en 2010

Evaluation of therapeutic targets in animal models of arthritis: how does it relate to rheumatoid arthritis?

artículo científico publicado en 2010

Experiences and needs for work participation in employees with rheumatoid arthritis treated with anti-tumour necrosis factor therapy

artículo científico publicado el 15 de junio de 2011

Expression of IL-20 in synovium and lesional skin of patients with psoriatic arthritis: differential response to alefacept treatment

artículo científico publicado el 24 de septiembre de 2012

FHL2 regulates the resolution of tissue damage in chronic inflammatory arthritis

artículo científico publicado en 2014

Female sex increases risk for rheumatoid arthritis only in individuals encoding low-risk HLA-DRB1 alleles

scientific article published on 01 June 2003

Fibroblast-like synoviocytes derived from patients with rheumatoid arthritis show the imprint of synovial tissue heterogeneity: evidence of a link between an increased myofibroblast-like phenotype and high-inflammation synovitis.

artículo científico publicado en 2005

Folate receptor beta as a potential delivery route for novel folate antagonists to macrophages in the synovial tissue of rheumatoid arthritis patients

artículo científico publicado en 2009

Function of histone deacetylase inhibitors in inflammation.

artículo científico publicado en 2011

Gene therapy targeting nuclear factor-kappaB: towards clinical application in inflammatory diseases and cancer

artículo científico publicado en 2009

Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk

artículo científico publicado en 2009

Genetics of rheumatoid arthritis contributes to biology and drug discovery

artículo científico publicado en 2013

Genome-wide association analysis of anti-TNF drug response in patients with rheumatoid arthritis

artículo científico publicado en 2012

Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci

artículo científico publicado en 2010

Genome-wide association study of response to methotrexate in early rheumatoid arthritis patients

article

Heterogeneous expression pattern of interleukin 17A (IL-17A), IL-17F and their receptors in synovium of rheumatoid arthritis, psoriatic arthritis and osteoarthritis: possible explanation for nonresponse to anti-IL-17 therapy?

artículo científico publicado en 2014

Histone deacetylase 3 regulates the inflammatory gene expression programme of rheumatoid arthritis fibroblast-like synoviocytes

scientific article published on 25 July 2016

Histone deacetylase inhibitors suppress inflammatory activation of rheumatoid arthritis patient synovial macrophages and tissue

artículo científico publicado en 2010

Histone deacetylase inhibitors suppress rheumatoid arthritis fibroblast-like synoviocyte and macrophage IL-6 production by accelerating mRNA decay

artículo científico publicado en 2011

How to perform and analyse synovial biopsies

artículo científico publicado en 2009

How to perform and analyse synovial biopsies

artículo científico publicado en 2013

Human Lymph Node Stromal Cells Have the Machinery to Regulate Peripheral Tolerance during Health and Rheumatoid Arthritis

artículo científico publicado en 2020

Human T-cell memory consists mainly of unexpanded clones.

artículo científico publicado en 2010

Human lymph-node CD8(+) T cells display an altered phenotype during systemic autoimmunity.

artículo científico publicado en 2016

Hunting for the pathogenesis of rheumatoid arthritis: core-needle biopsy of inguinal lymph nodes as a new research tool

artículo científico publicado el 11 de junio de 2012

Identification of interleukin-7 as a candidate disease mediator in spondylarthritis

scientific article published on 01 November 2008

Identification of synovial biomarkers of response to experimental treatment in early-phase clinical trials in spondylarthritis

artículo científico publicado en 2006

Identification of the epidermal growth factor-TM7 receptor EMR2 and its ligand dermatan sulfate in rheumatoid synovial tissue

artículo científico publicado en 2005

Immunoglobulin G4+ clones identified by next-generation sequencing dominate the B cell receptor repertoire in immunoglobulin G4 associated cholangitis

artículo científico publicado en 2013

Impact of intravenous abatacept on synovitis, osteitis and structural damage in patients with rheumatoid arthritis and an inadequate response to methotrexate: the ASSET randomised controlled trial

artículo científico publicado en 2012

Impaired lymph node stromal cell function during the earliest phases of rheumatoid arthritis

artículo científico publicado en 2018

In vitro spontaneous osteoclastogenesis of human peripheral blood mononuclear cells is not crucially dependent on T lymphocytes.

artículo científico publicado en 2009

Inflammation and ectopic lymphoid structures in rheumatoid arthritis synovial tissues dissected by genomics technology: identification of the interleukin-7 signaling pathway in tissues with lymphoid neogenesis

artículo científico publicado en 2007

Inflammatory cytokines epigenetically regulate rheumatoid arthritis fibroblast-like synoviocyte activation by suppressing HDAC5 expression

artículo científico publicado en 2014

Inflammatory memories: is epigenetics the missing link to persistent stromal cell activation in rheumatoid arthritis?

scientific article published on 09 April 2011

Inhibition of osteoclastogenesis and inflammatory bone resorption by targeting BET proteins and epigenetic regulation

artículo científico publicado en 2014

Insight into the Endocrine System and the Immune System: A Review of the Inflammatory Role of Prolactin in Rheumatoid Arthritis and Psoriatic Arthritis

artículo científico publicado en 2017

Integration of sequence data from a Consanguineous family with genetic data from an outbred population identifies PLB1 as a candidate rheumatoid arthritis risk gene

artículo científico publicado en 2014

Interferon beta for rheumatoid arthritis: new clothes for an old kid on the block

artículo científico publicado en 2009

Interleukin 1 receptor antagonist mediates the beneficial effects of systemic interferon beta in mice: implications for rheumatoid arthritis

scientific article published on 07 January 2011

Interleukin-17-positive mast cells contribute to synovial inflammation in spondylarthritis

artículo científico publicado en 2012

Intimal lining layer macrophages but not synovial sublining macrophages display an IL-10 polarized-like phenotype in chronic synovitis

artículo científico publicado el 11 de abril de 2012

Intracellular delivery of poly(I:C) induces apoptosis of fibroblast-like synoviocytes via an unknown dsRNA sensor.

artículo científico publicado en 2016

Involvement of breast cancer resistance protein expression on rheumatoid arthritis synovial tissue macrophages in resistance to methotrexate and leflunomide

artículo científico publicado en 2009

Is treat-to-target really working in rheumatoid arthritis? a longitudinal analysis of a cohort of patients treated in daily practice (RA BIODAM)

artículo científico publicado en 2020

JNK-dependent downregulation of FoxO1 is required to promote the survival of fibroblast-like synoviocytes in rheumatoid arthritis.

artículo científico publicado en 2014

Labeling of autologous monocytes with 99mTc-HMPAO at very high specific radioactivity

artículo científico publicado en 2007

Local Synovial Engagement of Angiogenic TIE‐2 Is Associated With the Development of Persistent Erosive Rheumatoid Arthritis in Patients With Early Arthritis

artículo científico publicado el 1 de diciembre de 2013

Loss of imprinting of IGF2 characterises high IGF2 mRNA-expressing type of fibroblast-like synoviocytes in rheumatoid arthritis

artículo científico publicado en 2009

Lymph node biopsy analysis reveals an altered immunoregulatory balance already during the at-risk phase of autoantibody positive rheumatoid arthritis.

artículo científico publicado en 2016

MLN3897 plus methotrexate in patients with rheumatoid arthritis: safety, efficacy, pharmacokinetics, and pharmacodynamics of an oral CCR1 antagonist in a phase IIa, double-blind, placebo-controlled, randomized, proof-of-concept study

artículo científico publicado en 2009

MRI assessment of suppression of structural damage in patients with rheumatoid arthritis receiving rituximab: results from the randomised, placebo-controlled, double-blind RA-SCORE study

artículo científico publicado en 2014

Mediators of structural remodeling in peripheral spondylarthritis

artículo científico publicado en 2009

Microscopic measurement of inflammation in synovial tissue: inter-observer agreement for manual quantitative, semiquantitative and computerised digital image analysis

artículo científico publicado en 2007

Modulation of CCR2 in rheumatoid arthritis: a double-blind, randomized, placebo-controlled clinical trial

artículo científico publicado en 2008

Molecular Characterization of Human Lymph Node Stromal Cells During the Earliest Phases of Rheumatoid Arthritis

scientific article published on 20 August 2019

Monitoring the T-cell receptor repertoire at single-clone resolution.

artículo científico publicado en 2006

Monocyte scintigraphy in rheumatoid arthritis: the dynamics of monocyte migration in immune-mediated inflammatory disease

artículo científico publicado en 2009

NF-κB-inducing kinase is a key regulator of inflammation-induced and tumour-associated angiogenesis.

artículo científico publicado en 2014

New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis

artículo científico publicado en 2015

Non-canonical NF-κB signaling in rheumatoid arthritis: Dr Jekyll and Mr Hyde?

artículo científico

Non-response to rituximab therapy in rheumatoid arthritis is associated with incomplete disruption of the B cell receptor repertoire

artículo científico publicado en 2019

Novel approaches for the treatment of rheumatoid arthritis: lessons from the evaluation of synovial biomarkers in clinical trials

artículo científico publicado en 2008

Nuclear Factor-κB-inducing Kinase Is Expressed in Synovial Endothelial Cells in Patients with Early Arthritis and Correlates with Markers of Inflammation: A Prospective Cohort Study

artículo científico publicado en 2015

OMERACT 10 Sharp Symposium: important findings in examination of imaging methods for measurement of joint damage in rheumatoid arthritis

artículo científico

Outcomes and Findings of the International Rheumatoid Arthritis (RA) BIODAM Cohort for Validation of Soluble Biomarkers in RA

scientific article published on 01 September 2019

Overexpression of toll-like receptors 3 and 4 in synovial tissue from patients with early rheumatoid arthritis: toll-like receptor expression in early and longstanding arthritis

artículo científico publicado en 2008

Pathogenesis of spondyloarthritis: autoimmune or autoinflammatory?

artículo científico

Pathogenesis of spondyloarthritis: insights from synovial membrane studies

artículo científico publicado en 2006

Patient global assessment in psoriatic arthritis: a multicenter GRAPPA and OMERACT study

artículo científico publicado en 2011

Peripheral joint inflammation in early onset spondyloarthritis is not specifically related to enthesitis

artículo científico publicado el 25 de abril de 2013

Physician’s Global Assessment in Psoriatic Arthritis: A Multicenter GRAPPA Study

scientific article published on 15 June 2018

Pixel-by-pixel analysis of DCE MRI curve patterns and an illustration of its application to the imaging of the musculoskeletal system

artículo científico publicado en 2006

Possible role of shared epitope status in the relationship between matrix metalloproteinase 3 genotype and radiographic progression of rheumatoid arthritis: comment on the article by Constantin et al

artículo científico publicado en 2003

Preclinical Potency and Biodistribution Studies of an AAV 5 Vector Expressing Human Interferon-β (ART-I02) for Local Treatment of Patients with Rheumatoid Arthritis

artículo científico publicado en 2015

Preclinical and clinical investigation of a CCR5 antagonist, AZD5672, in patients with rheumatoid arthritis receiving methotrexate

artículo científico publicado en 2010

Presence and Role of Anti–Citrullinated Protein Antibodies in Experimental Arthritis Models

artículo científico publicado el 1 de abril de 2013

Presence of lymphocyte aggregates in the synovium of patients with early arthritis in relationship to diagnosis and outcome: is it a constant feature over time?

artículo científico publicado el 20 de diciembre de 2010

Prevalence of Anti-Citrullinated Protein Antibodies and IgM Rheumatoid Factor in First-Degree Relatives of Dutch Rheumatoid Arthritis Patients

artículo científico publicado en 2015

Pro-atherogenic lipid changes and decreased hepatic LDL receptor expression by tocilizumab in rheumatoid arthritis.

artículo científico publicado en 2013

Progression of structural damage is not related to rituximab serum levels in rheumatoid arthritis patients

artículo científico publicado en 2013

Promotion of macrophage activation by Tie2 in the context of the inflamed synovia of rheumatoid arthritis and psoriatic arthritis patients

scientific article published on 01 February 2020

Rap1 signaling is required for suppression of Ras-generated reactive oxygen species and protection against oxidative stress in T lymphocytes

artículo científico publicado en 2004

Real-time quantitative PCR to detect changes in synovial gene expression in rheumatoid arthritis after corticosteroid treatment

artículo científico publicado en 2006

Reduced CLEC9A expression in synovial tissue of psoriatic arthritis patients after adalimumab therapy

artículo científico publicado en 2016

Reduction of proinflammatory cytokine expression in the synovium by targeting IKKbeta in vivo in a rat model

scientific article published on 01 November 2006

Regulation of IFN response gene activity during infliximab treatment in rheumatoid arthritis is associated with clinical response to treatment

artículo científico publicado en 2010

Relationship between inflammation, bone destruction, and osteoproliferation in the HLA–B27/human β2‐microglobulin–transgenic rat model of spondylarthritis

artículo científico publicado el 1 de octubre de 2012

Relationship between the type I interferon signature and the response to rituximab in rheumatoid arthritis patients

artículo científico publicado en 2010

Reliability of computerized image analysis for the evaluation of serial synovial biopsies in randomized controlled trials in rheumatoid arthritis

artículo científico publicado en 2005

Response to rituximab in patients with rheumatoid arthritis in different compartments of the immune system

artículo científico publicado el 1 de noviembre de 2011

Rheumatoid arthritis risk allele PTPRC is also associated with response to anti-tumor necrosis factor alpha therapy

artículo científico publicado en 2010

Rheumatoid arthritis synovium contains two subsets of CD83-DC-LAMP- dendritic cells with distinct cytokine profiles

artículo científico publicado en 2008

Rheumatoid synovial inflammation: pixel-by-pixel dynamic contrast-enhanced MR imaging time-intensity curve shape analysis--a feasibility study

artículo científico publicado en 2009

Rituximab abrogates joint destruction in rheumatoid arthritis by inhibiting osteoclastogenesis

artículo científico publicado el 8 de noviembre de 2011

Role of the cholinergic nervous system in rheumatoid arthritis: aggravation of arthritis in nicotinic acetylcholine receptor α7 subunit gene knockout mice

artículo científico publicado en 2010

SAFETY, BIODISTRIBUTION, AND EFFICACY OF AN AAV-5 VECTOR ENCODING HUMAN INTERFERON-BETA (ART-I02) DELIVERED VIA INTRA-ARTICULAR INJECTION IN RHESUS MONKEYS WITH COLLAGEN-INDUCED ARTHRITIS.

artículo científico publicado en 2015

Sa.17. A Functional Variant of TIR-domain-containing Adaptor Protein (TIRAP) is Not Associated with Spondyloarthritis

Safety with ocrelizumab in rheumatoid arthritis: results from the ocrelizumab phase III program

scientific article published on 03 February 2014

Selective involvement of ERK and JNK mitogen-activated protein kinases in early rheumatoid arthritis (1987 ACR criteria compared to 2010 ACR/EULAR criteria): a prospective study aimed at identification of diagnostic and prognostic biomarkers as well

artículo científico publicado en 2011

Serum Vaspin Levels Are Associated with the Development of Clinically Manifest Arthritis in Autoantibody-Positive Individuals

artículo científico publicado en 2015

Serum macrophage inhibitory cytokine 1 in rheumatoid arthritis: a potential marker of erosive joint destruction

scientific article published on 01 March 2007

Signal Transduction Pathways in Chronic Inflammatory Autoimmune Disease: Small GTPases

artículo científico publicado el 7 de septiembre de 2012

Signal transduction pathways and transcription factors as therapeutic targets in inflammatory disease: towards innovative antirheumatic therapy

artículo científico publicado en 2005

Silencing the expression of Ras family GTPase homologues decreases inflammation and joint destruction in experimental arthritis

artículo científico publicado en 2010

Single-joint Assessment for the Evaluation of Intraarticular Treatment: Responsiveness and Discrimination of the Composite Change Index

artículo científico publicado en 2015

Smelling the Diagnosis: The Electronic Nose as Diagnostic Tool in Inflammatory Arthritis. A Case-Reference Study

artículo científico publicado en 2016

Smoking and overweight determine the likelihood of developing rheumatoid arthritis

scientific article published on 27 October 2012

Soluble Biomarkers of Cartilage and Bone Metabolism in Early Proof of Concept Trials in Psoriatic Arthritis: Effects of Adalimumab Versus Placebo

artículo científico publicado el 3 de septiembre de 2010

Soluble immune complexes shift the TLR-induced cytokine production of distinct polarized human macrophage subsets towards IL-10

artículo científico publicado el 26 de abril de 2012

Somatic Variation of T-Cell Receptor Genes Strongly Associate with HLA Class Restriction

artículo científico publicado en 2015

Spondylarthritis in the absence of B lymphocytes

scientific article published on 01 March 2008

Stimulation of nicotinic acetylcholine receptors attenuates collagen-induced arthritis in mice

artículo científico publicado en 2009

Stromal cell markers are differentially expressed in the synovial tissue of patients with early arthritis.

artículo científico publicado en 2017

Sustained Rap1 activation in autoantigen-specific T lymphocytes attenuates experimental autoimmune encephalomyelitis

artículo científico publicado en 2012

Sustained T cell Rap1 signaling is protective in the collagen-induced arthritis model of rheumatoid arthritis

artículo científico publicado en 2010

Synovial IL-21/TNF-producing CD4+ T cells induce joint destruction in rheumatoid arthritis by inducing matrix metalloproteinase production by fibroblast-like synoviocytes

artículo científico publicado en 2016

Synovial and mucosal immunopathology in spondyloarthritis

artículo científico publicado en 2009

Synovial lymphoid neogenesis does not define a specific clinical rheumatoid arthritis phenotype

artículo científico publicado en 2008

Synovial macrophages as a biomarker of response to therapeutic intervention in rheumatoid arthritis: standardization and consistency across centers

article

Synovial microparticles from arthritic patients modulate chemokine and cytokine release by synoviocytes

artículo científico publicado en 2005

Synovial tissue analysis for the discovery of diagnostic and prognostic biomarkers in patients with early arthritis.

artículo científico publicado en 2011

Synovial tissue heterogeneity in rheumatoid arthritis in relation to disease activity and biomarkers in peripheral blood

artículo científico publicado en 2010

Synovial tissue research: a state-of-the-art review

artículo científico publicado en 2017

Synovial tissue research: a state-of-the-art review

artículo científico publicado en 2017

Synovial tissue response to treatment in rheumatoid arthritis

artículo científico

Synovitis in psoriatic arthritis: immunohistochemistry, comparisons with rheumatoid arthritis, and effects of therapy

artículo científico publicado en 2011

TYK2 protein-coding variants protect against rheumatoid arthritis and autoimmunity, with no evidence of major pleiotropic effects on non-autoimmune complex traits

artículo científico publicado en 2015

Tailored therapy for rheumatic disease within reach

artículo científico publicado el 1 de enero de 2011

Targeting B cells in immune-mediated inflammatory disease: a comprehensive review of mechanisms of action and identification of biomarkers

artículo científico publicado en 2010

Targeting cellular adhesion molecules, chemokines and chemokine receptors in rheumatoid arthritis

artículo científico publicado en 2005

Targeting histone deacetylase activity in rheumatoid arthritis and asthma as prototypes of inflammatory disease: should we keep our HATs on?

artículo científico publicado en 2008

Tertiary Lymphoid Structures in Rheumatoid Arthritis: NF-κB-Inducing Kinase-Positive Endothelial Cells as Central Players.

artículo científico publicado en 2015

The 2010 American College of Rheumatology/European League Against Rheumatism classification criteria for rheumatoid arthritis: Phase 2 methodological report

artículo científico publicado en 2010

The Presumed Hyporesponsive Behavior of Rheumatoid Arthritis T Lymphocytes Can Be Attributed to Spontaneous Ex Vivo Apoptosis rather than Defects in T Cell Receptor Signaling

artículo científico publicado en 2009

The Ras guanine nucleotide exchange factor RasGRF1 promotes matrix metalloproteinase-3 production in rheumatoid arthritis synovial tissue

artículo científico publicado en 2009

The abundant synovial expression of the RANK/RANKL/Osteoprotegerin system in peripheral spondylarthritis is partially disconnected from inflammation

artículo científico publicado en 2008

The alpha7 nicotinic acetylcholine receptor on fibroblast-like synoviocytes and in synovial tissue from rheumatoid arthritis patients: a possible role for a key neurotransmitter in synovial inflammation

artículo científico publicado en 2009

The bromodomain protein inhibitor I-BET151 suppresses expression of inflammatory genes and matrix degrading enzymes in rheumatoid arthritis synovial fibroblasts.

artículo científico publicado en 2014

The cholinergic anti-inflammatory pathway: towards innovative treatment of rheumatoid arthritis

artículo científico publicado en 2009

The costimulatory molecule CD27 maintains clonally diverse CD8(+) T cell responses of low antigen affinity to protect against viral variants

artículo científico publicado en 2011

The development of candidate composite disease activity and responder indices for psoriatic arthritis (GRACE project)

artículo científico publicado en 2012

The dynamics of macrophage lineage populations in inflammatory and autoimmune diseases

scientific article published on May 2009

The features of the synovium in early rheumatoid arthritis according to the 2010 ACR/EULAR classification criteria

artículo científico publicado en 2012

The gene expression profile in the synovium as a predictor of the clinical response to infliximab treatment in rheumatoid arthritis

artículo científico publicado en 2010

The interaction of smoking and the HLA-DRB1 shared epitope in rheumatoid factor-positive rheumatoid arthritis: Comment on the article by Padyukov et al

artículo científico publicado en 2005

The presence of citrullinated proteins is not specific for rheumatoid synovial tissue

artículo científico publicado en 2004

The relationship between synovial lymphocyte aggregates and the clinical response to infliximab in rheumatoid arthritis: a prospective study

artículo científico publicado en 2009

The value of rheumatoid factor and anti-citrullinated protein antibodies as predictors of response to infliximab in rheumatoid arthritis: an exploratory study

artículo científico publicado el 30 de marzo de 2011

Therapeutic options for targeting inflammatory osteoarthritis pain

scientific article published on 01 June 2019

Tie2 signaling cooperates with TNF to promote the pro-inflammatory activation of human macrophages independently of macrophage functional phenotype

artículo científico publicado en 2014

Timing the therapeutic window of opportunity in early rheumatoid arthritis: proposal for definitions of disease duration in clinical trials

artículo científico publicado en 2012

Towards prevention of autoantibody-positive rheumatoid arthritis: from lifestyle modification to preventive treatment

artículo científico publicado en 2016

Treatment with recombinant interferon-beta reduces inflammation and slows cartilage destruction in the collagen-induced arthritis model of rheumatoid arthritis

artículo científico publicado en 2004

Triggering of the dsRNA sensors TLR3, MDA5, and RIG-I induces CD55 expression in synovial fibroblasts

artículo científico publicado en 2012

Tumor necrosis factor alpha drives cadherin 11 expression in rheumatoid inflammation

artículo científico publicado en 2008

Tumor necrosis factor antagonist mechanisms of action: a comprehensive review

artículo científico publicado en 2007

Tumor necrosis factor inhibition modulates thrombospondin-1 expression in human inflammatory joint disease through altered NR4A2 activity.

artículo científico publicado en 2013

Two novel α7 nicotinic acetylcholine receptor ligands: in vitro properties and their efficacy in collagen-induced arthritis in mice

artículo científico publicado en 2015

Type I IFN and TNFα cross-regulation in immune-mediated inflammatory disease: basic concepts and clinical relevance.

scientific article published on 28 October 2010

Type I interferons have no major influence on humoral autoimmunity in rheumatoid arthritis.

artículo científico publicado en 2009

Undifferentiated spondyloarthritis vs ankylosing spondylitis and psoriatic arthritis: a real-life prospective cohort study of clinical presentation and response to treatment

artículo científico publicado el 16 de julio de 2013

Vagus nerve stimulation inhibits cytokine production and attenuates disease severity in rheumatoid arthritis

artículo científico publicado en 2016

Why CCR2 and CCR5 blockade failed and why CCR1 blockade might still be effective in the treatment of rheumatoid arthritis

artículo científico publicado en 2011