Lista de obras -

A new crystal form of human histidine triad nucleotide-binding protein 1 (hHINT1) in complex with adenosine 5′-monophosphate at 1.38 Å resolution

artículo científico publicado en 2012

Biochemical, crystallographic, and mutagenic characterization of hint, the AMP-lysine hydrolase, with novel substrates and inhibitors

artículo científico publicado en 2004

Coordinate expression of NADPH-dependent flavin reductase, Fre-1, and Hint-related 7meGMP-directed hydrolase, DCS-1

artículo científico publicado en 2003

Crystallographic studies of the complex of human HINT1 protein with a non-hydrolyzable analog of Ap4A

artículo científico publicado en 2016

Designed FHIT alleles establish that Fhit-induced apoptosis in cancer cells is limited by substrate binding

artículo científico publicado en 2003

Diaryl ethers with carboxymethoxyphenacyl motif as potent HIV-1 reverse transcriptase inhibitors with improved solubility.

artículo científico publicado en 2018

Escherichia coli tRNA 2-Selenouridine Synthase (SelU): Elucidation of Substrate Specificity to Understand the Role of S-Geranyl-tRNA in the Conversion of 2-Thio- into 2-Selenouridines in Bacterial tRNA

artículo científico publicado en 2022

Escherichia coli tRNA 2-selenouridine synthase SelU selects its prenyl substrate to accomplish its enzymatic function

artículo científico publicado en 2022

Evaluation of influence of Ap4A analogues on Fhit-positive HEK293T cells; cytotoxicity and ability to induce apoptosis

artículo científico publicado en 2011

Expression of somatostatin receptor subtype 3 in the gastric mucosa of dyspeptic patients in relation to Helicobacter pylori infection and a family history of gastric cancer

scientific article published on 07 August 2007

Helicobacter pylori infection and family history of gastric cancer decrease expression of FHIT tumor suppressor gene in gastric mucosa of dyspeptic patients

artículo científico publicado en 2009

High-resolution X-ray structure of the rabbit histidine triad nucleotide-binding protein 1 (rHINT1)-adenosine complex at 1.10 Å resolution

artículo científico publicado en 2011

Histidine triad nucleotide-binding protein 1 (HINT-1) phosphoramidase transforms nucleoside 5'-O-phosphorothioates to nucleoside 5'-O-phosphates

artículo científico publicado en 2010

Inhibition of plasminogen activator inhibitor release in endothelial cell cultures by antisense oligodeoxyribonucleotides with a 5'-end lipophilic modification.

artículo científico publicado en 1999

Interactions of cellular histidine triad nucleotide binding protein 1 with nucleosides 5'-O-monophosphorothioate and their derivatives - Implication for desulfuration process in the cell

artículo científico publicado en 2014

LNA units present in the (2'-OMe)-RNA strand stabilize parallel duplexes (2'-OMe)-RNA/[All-R(P)-PS]-DNA and parallel triplexes (2'-OMe)-RNA/[All-R(P)-PS]-DNA/RNA. An improved tool for the inhibition of reverse transcription

artículo científico publicado en 2015

N-Acyl-phosphoramidates as potential novel form of gemcitabine prodrugs.

artículo científico publicado en 2014

New interactions between tumor suppressor Fhit protein and a nonhydrolyzable analog of its AP4 A substrate

artículo científico publicado en 2017

Phosphorothioate analogs of P1,P3-di(nucleosid-5'-yl) triphosphates: Synthesis, assignment of the absolute configuration at P-atoms and P-stereodependent recognition by Fhit hydrolase

artículo científico publicado en 2016

Searching for novel scaffold of triazole non-nucleoside inhibitors of HIV-1 reverse transcriptase

artículo científico publicado en 2015

Stereochemical Course of Escherichia coli RNase H.

artículo científico publicado en 2003

Stereochemical course of Escherichia coli RNase H.

artículo científico publicado en 2002

Stereochemistry of rHint1 hydrolase assisted cleavage of P-N bond in nucleoside 5'-O-phosphoramidothioates

artículo científico publicado en 2007

Stereodifferentiation--the effect of P chirality of oligo(nucleoside phosphorothioates) on the activity of bacterial RNase H.

artículo científico publicado en 1995

Synthesis, biochemical and biological studies on oligonucleotides bearing a lipophilic dimethoxytrityl group

artículo científico publicado en 1998

The role of the Hint1 protein in the metabolism of phosphorothioate oligonucleotides drugs and prodrugs, and the release of H2S under cellular conditions

scientific article published on 14 February 2019

[Histidine triad protein superfamily--biological function and enzymatic activity]

artículo científico publicado en 2012

[Oligonucleotides with aptameric properties]

artículo científico publicado en 1998

[Somatostatin receptor subtype 3 (SSTR3) mRNA level in gastric mucosa of patients with dyspepsia]

artículo científico publicado en 2007

Lista de obras de

A new crystal form of human histidine triad nucleotide-binding protein 1 (hHINT1) in complex with adenosine 5′-monophosphate at 1.38 Å resolution

Biochemical, crystallographic, and mutagenic characterization of hint, the AMP-lysine hydrolase, with novel substrates and inhibitors

Coordinate expression of NADPH-dependent flavin reductase, Fre-1, and Hint-related 7meGMP-directed hydrolase, DCS-1

Crystallographic studies of the complex of human HINT1 protein with a non-hydrolyzable analog of Ap4A

Designed FHIT alleles establish that Fhit-induced apoptosis in cancer cells is limited by substrate binding

Diaryl ethers with carboxymethoxyphenacyl motif as potent HIV-1 reverse transcriptase inhibitors with improved solubility.

Escherichia coli tRNA 2-Selenouridine Synthase (SelU): Elucidation of Substrate Specificity to Understand the Role of S-Geranyl-tRNA in the Conversion of 2-Thio- into 2-Selenouridines in Bacterial tRNA

Escherichia coli tRNA 2-selenouridine synthase SelU selects its prenyl substrate to accomplish its enzymatic function

Evaluation of influence of Ap4A analogues on Fhit-positive HEK293T cells; cytotoxicity and ability to induce apoptosis

Expression of somatostatin receptor subtype 3 in the gastric mucosa of dyspeptic patients in relation to Helicobacter pylori infection and a family history of gastric cancer

Helicobacter pylori infection and family history of gastric cancer decrease expression of FHIT tumor suppressor gene in gastric mucosa of dyspeptic patients

High-resolution X-ray structure of the rabbit histidine triad nucleotide-binding protein 1 (rHINT1)-adenosine complex at 1.10 Å resolution

Histidine triad nucleotide-binding protein 1 (HINT-1) phosphoramidase transforms nucleoside 5'-O-phosphorothioates to nucleoside 5'-O-phosphates

Inhibition of plasminogen activator inhibitor release in endothelial cell cultures by antisense oligodeoxyribonucleotides with a 5'-end lipophilic modification.

Interactions of cellular histidine triad nucleotide binding protein 1 with nucleosides 5'-O-monophosphorothioate and their derivatives - Implication for desulfuration process in the cell

LNA units present in the (2'-OMe)-RNA strand stabilize parallel duplexes (2'-OMe)-RNA/[All-R(P)-PS]-DNA and parallel triplexes (2'-OMe)-RNA/[All-R(P)-PS]-DNA/RNA. An improved tool for the inhibition of reverse transcription

N-Acyl-phosphoramidates as potential novel form of gemcitabine prodrugs.

New interactions between tumor suppressor Fhit protein and a nonhydrolyzable analog of its AP4 A substrate

Phosphorothioate analogs of P1,P3-di(nucleosid-5'-yl) triphosphates: Synthesis, assignment of the absolute configuration at P-atoms and P-stereodependent recognition by Fhit hydrolase

Searching for novel scaffold of triazole non-nucleoside inhibitors of HIV-1 reverse transcriptase

Stereochemical Course of Escherichia coli RNase H.

Stereochemical course of Escherichia coli RNase H.

Stereochemistry of rHint1 hydrolase assisted cleavage of P-N bond in nucleoside 5'-O-phosphoramidothioates

Stereodifferentiation--the effect of P chirality of oligo(nucleoside phosphorothioates) on the activity of bacterial RNase H.

Synthesis, biochemical and biological studies on oligonucleotides bearing a lipophilic dimethoxytrityl group

The role of the Hint1 protein in the metabolism of phosphorothioate oligonucleotides drugs and prodrugs, and the release of H2S under cellular conditions

[Histidine triad protein superfamily--biological function and enzymatic activity]

[Oligonucleotides with aptameric properties]

[Somatostatin receptor subtype 3 (SSTR3) mRNA level in gastric mucosa of patients with dyspepsia]