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A heat-shock response regulated by the PfAP2-HS transcription factor protects human malaria parasites from febrile temperatures

artículo científico publicado en 2021

A single-nucleotide polymorphism in a Plasmodium berghei ApiAP2 transcription factor alters the development of host immunity

artículo científico publicado en 2020

Antimalarial pantothenamide metabolites target acetyl-coenzyme A biosynthesis in Plasmodium falciparum

artículo científico publicado en 2019

Artemisinin-resistant K13 mutations rewire Plasmodium falciparum's intra-erythrocytic metabolic program to enhance survival

artículo científico publicado en 2021

Genetic ablation of the mitoribosome in the malaria parasite Plasmodium falciparum sensitizes it to antimalarials that target mitochondrial functions

scientific article published on 09 April 2020

Increased circulation time of Plasmodium falciparum underlies persistent asymptomatic infection in the dry season

artículo científico publicado en 2020

Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics

artículo científico publicado en 2018

Multistage and transmission-blocking targeted antimalarials discovered from the open-source MMV Pandemic Response Box

artículo científico publicado en 2021

Niemann-Pick type C1-related protein is a druggable target required for parasite membrane homeostasis

artículo científico publicado en 2019

Open-source discovery of chemical leads for next-generation chemoprotective antimalarials

scientific article published on 01 December 2018

Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183

artículo científico publicado en 2022

Refining the transcriptome of the human malaria parasite Plasmodium falciparum using amplification-free RNA-seq

artículo científico publicado en 2020

The G9a Histone Methyltransferase Inhibitor BIX-01294 Modulates Gene Expression during Plasmodium falciparum Gametocyte Development and Transmission

artículo científico publicado en 2019

The natural function of the malaria parasite's chloroquine resistance transporter

artículo científico publicado en 2020