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A Rare Mutation in SPLUNC1 Affects Bacterial Adherence and Invasion in Meningococcal Disease

scientific article published on 01 July 2019

A common TMPRSS2 variant has a protective effect against severe COVID-19

artículo científico publicado en 2022

Age-dependent Mendelian predisposition to herpes simplex virus type 1 encephalitis in childhood

artículo científico publicado en 2010

Association of Country Income Level With the Characteristics and Outcomes of Critically Ill Patients Hospitalized With Acute Kidney Injury and COVID-19

artículo científico publicado en 2023

Autophagy-Virus Interplay: From Cell Biology to Human Disease

article published in 2018

Bacterial Autophagy: How to Take a Complement.

artículo científico publicado en 2018

COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study

artículo científico publicado en 2021

Characterisation of in-hospital complications associated with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol UK: a prospective, multicentre cohort study

artículo científico publicado en 2021

Co-infections, secondary infections, and antimicrobial use in patients hospitalised with COVID-19 during the first pandemic wave from the ISARIC WHO CCP-UK study: a multicentre, prospective cohort study

scientific article published in 2021

Defects in <i>LC3B2</i> and <i>ATG4A</i> underlie HSV2 meningitis and reveal a critical role for autophagy in antiviral defense in humans

scientific article published on 01 December 2020

Development and validation of the ISARIC 4C Deterioration model for adults hospitalised with COVID-19: a prospective cohort study

artículo científico publicado en 2021

Early ''relapse'' after herpetic encephalitis: extensive white matter lesions in an infant with interferon production deficit

artículo científico publicado en 2010

Genetic susceptibility to herpes simplex virus 1 encephalitis in mice and humans

artículo científico publicado en 2007

Herpes simplex encephalitis in children with autosomal recessive and dominant TRIF deficiency

artículo científico publicado en 2011

Herpes simplex virus encephalitis in a patient with complete TLR3 deficiency: TLR3 is otherwise redundant in protective immunity

artículo científico publicado en 2011

Heterozygous TBK1 mutations impair TLR3 immunity and underlie herpes simplex encephalitis of childhood

artículo científico publicado en 2012

Human Adaptive Immunity Rescues an Inborn Error of Innate Immunity.

artículo científico publicado en 2017

Human TBK1 deficiency leads to autoinflammation driven by TNF-induced cell death

artículo científico publicado en 2021

Human TBK1 is required for early autophagy induction upon HSV1 infection

article

Human TBK1: A Gatekeeper of Neuroinflammation

artículo científico publicado en 2016

Human TRAF3 adaptor molecule deficiency leads to impaired Toll-like receptor 3 response and susceptibility to herpes simplex encephalitis

artículo científico publicado en 2010

Human Toll-like receptor-dependent induction of interferons in protective immunity to viruses

artículo científico publicado en 2007

Human genetic and immunological determinants of critical COVID-19 pneumonia

artículo científico publicado en 2022

Human genetics of meningococcal infections

artículo científico publicado en 2020

Human primary immunodeficiencies of type I interferons

artículo científico publicado en 2007

IRAK4 Deficiency Presenting with Anti-NMDAR Encephalitis and HHV6 Reactivation

artículo científico publicado en 2020

Implementation of corticosteroids in treatment of COVID-19 in the ISARIC WHO Clinical Characterisation Protocol UK: prospective, cohort study

artículo científico publicado en 2022

Inborn errors of anti-viral interferon immunity in humans

artículo científico publicado en 2011

Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

scientific article published on 24 September 2020

Macrophage Exosomes Induce Placental Inflammatory Cytokines: A Novel Mode of Maternal-Placental Messaging

artículo científico publicado en 2015

Mitochondria mediate septin cage assembly to promote autophagy of Shigella

artículo científico publicado en 2016

Molecular genetic analysis of two loci (Ity2 and Ity3) involved in the host response to infection with Salmonella typhimurium using congenic mice and expression profiling

artículo científico publicado en 2007

NEMO is a key component of NF-κB- and IRF-3-dependent TLR3-mediated immunity to herpes simplex virus.

artículo científico publicado en 2011

Non-steroidal anti-inflammatory drug use and outcomes of COVID-19 in the ISARIC Clinical Characterisation Protocol UK cohort: a matched, prospective cohort study

artículo científico publicado en 2021

Pediatric Herpes Simplex Virus Encephalitis Complicated by N-Methyl-D-aspartate Receptor Antibody Encephalitis

artículo científico publicado en 2014

Regulated proteolysis of p62/SQSTM1 enables differential control of autophagy and nutrient sensing

artículo científico publicado en 2018

Risk of adverse outcomes in patients with underlying respiratory conditions admitted to hospital with COVID-19: a national, multicentre prospective cohort study using the ISARIC WHO Clinical Characterisation Protocol UK

artículo científico publicado en 2021

SARS-CoV-2-related MIS-C: A key to the viral and genetic causes of Kawasaki disease?

SARS-CoV-2-specific nasal IgA wanes 9 months after hospitalisation with COVID-19 and is not induced by subsequent vaccination

artículo científico publicado en 2023

Sequencing, expression, and functional analyses support the candidacy of Ncf2 in susceptibility to Salmonella typhimurium infection in wild-derived mice

artículo científico publicado en 2006

Shigella sonnei infection of zebrafish reveals that O-antigen mediates neutrophil tolerance and dysentery incidence

scientific article published on 12 December 2019

TLR3 controls constitutive IFN-β antiviral immunity in human fibroblasts and cortical neurons

artículo científico publicado en 2021

TLR3 deficiency in patients with herpes simplex encephalitis

artículo científico publicado en 2007

TLR3 immunity to infection in mice and humans

artículo científico publicado en 2013

The emerging role of human TBK1 in virus-induced autophagy

artículo científico publicado en 2019

The proteome of Toll-like receptor 3-stimulated human immortalized fibroblasts: implications for susceptibility to herpes simplex virus encephalitis

artículo científico publicado en 2013

The value of open-source clinical science in pandemic response: lessons from ISARIC

artículo científico publicado en 2021

Tlr5 is not primarily associated with susceptibility to Salmonella Typhimurium infection in MOLF/Ei mice

artículo científico publicado en 2006

Whole-exome sequencing for the identification of rare variants in primary immunodeficiency genes in children with sepsis - a prospective population-based cohort study

artículo científico publicado en 2020

p62 and NDP52 proteins target intracytosolic Shigella and Listeria to different autophagy pathways

artículo científico publicado en 2011

Guía para el uso y la interpretación de ensayos para el seguimiento de la autofagia (4ª edición)

artículo científico