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A confocal microscopic analysis of galaninergic hyperinnervation of cholinergic basal forebrain neurons in Alzheimer's disease

artículo científico publicado en 1997

A novel approach for long-term oral drug administration in animal research ⬇️

artículo científico publicado el 14 de diciembre de 2010

A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease

artículo científico publicado en 2005

Age-Related Vulnerability of Developing Cholinergic Basal Forebrain Neurons Following Excitotoxic Lesions of the Hippocampus ⬇️

artículo científico publicado el 1 de agosto de 1994

Age-related declines in nigral neuronal function correlate with motor impairments in rhesus monkeys

artículo científico publicado en 1998

Age-related decreases in GTP-cyclohydrolase-I immunoreactive neurons in the monkey and human substantia nigra

scientific article published on 01 October 2000

Age-related decreases in Nurr1 immunoreactivity in the human substantia nigra

artículo científico publicado en 2002

Age-related shrinkage of cortically projecting cholinergic neurons: a selective effect

artículo científico publicado en 1987

Aged chimpanzees exhibit pathologic hallmarks of Alzheimer's disease

artículo científico publicado en 2017

Alpha7 nicotinic receptor up-regulation in cholinergic basal forebrain neurons in Alzheimer disease.

artículo científico publicado en 2007

Alz-50 immunoreactive neuropil differentiates hippocampal complex subfields in Alzheimer's disease

artículo científico publicado en 1991

Alzheimer's disease pathology in the neocortex and hippocampus of the western lowland gorilla (Gorilla gorilla gorilla).

artículo científico publicado en 2013

Alzheimer's disease-like dystrophic neurites characteristically associated with senile plaques are not found within other neurodegenerative diseases unless amyloid beta-protein deposition is present

artículo científico publicado en 1993

Apolipoprotein E immunoreactivity in neurons and neurofibrillary degeneration of aged non-demented and Alzheimer's disease patients

artículo científico publicado en 2001

Apolipoprotein E immunoreactivity within neurofibrillary tangles: relationship to Tau and PHF in Alzheimer's disease

scientific article published on 01 April 1995

Apolipoprotein E in Guamanian amyotrophic lateral sclerosis/ parkinsonism-dementia complex: genotype analysis and relationships to neuropathological changes

article

Apolipoprotein E-immunoreactivity in aged rhesus monkey cortex: colocalization with amyloid plaques

artículo científico publicado en 1994

Ascending cholinergic pathways: functional organization and implications for disease models

artículo científico publicado en 1993

Association of early experience with neurodegeneration in aged primates

artículo científico publicado en 2009

Astrocytic changes with aging and Alzheimer's disease-type pathology in chimpanzees

scientific article published on 07 January 2019

Atlas of cholinergic neurons in the forebrain and upper brainstem of the macaque based on monoclonal choline acetyltransferase immunohistochemistry and acetylcholinesterase histochemistry

artículo científico publicado en 1984

Atrophy of cholinergic basal forebrain neurons following excitotoxic cortical lesions is reversed by intravenous administration of an NGF conjugate

artículo científico publicado en 1996

Attentional function and basal forebrain cholinergic neuron morphology during aging in the Ts65Dn mouse model of Down syndrome

artículo científico publicado en 2015

Beta-amyloid deposition and functional impairment in the retina of the APPswe/PS1DeltaE9 transgenic mouse model of Alzheimer's disease

artículo científico publicado en 2008

Bioactivity of AAV2‐neurturin gene therapy (CERE‐120): Differences between Parkinson's disease and nonhuman primate brains ⬇️

artículo científico publicado el 18 de noviembre de 2010

Biomarkers for the Early Detection and Progression of Alzheimer's Disease

artículo científico publicado en 2016

Braak Stage, Cerebral Amyloid Angiopathy, and Cognitive Decline in Early Alzheimer's Disease

scientific article published on 01 January 2020

Braak stage and trajectory of cognitive decline in noncognitively impaired elders

artículo científico publicado en 2016

Braak staging, plaque pathology, and APOE status in elderly persons without cognitive impairment

artículo científico publicado en 2015

Brain-derived neurotrophic factor (BDNF) and TrkB hippocampal gene expression are putative predictors of neuritic plaque and neurofibrillary tangle pathology

artículo científico publicado en 2019

Brainstem Alzheimer's-like pathology in the triple transgenic mouse model of Alzheimer's disease

artículo científico publicado en 2009

Carrier mediated delivery of NGF: Alterations in basal forebrain neurons in aged rats revealed using antibodies against low and high affinity NGF receptors ⬇️

artículo científico publicado el 13 de octubre de 1997

Cellular Delivery of NGF Does Not Alter the Expression of β-Amyloid Immunoreactivity in Young or Aged Nonhuman Primates ⬇️

artículo científico publicado el 1 de junio de 1997

Central cholinergic pathways in the rat: an overview based on an alternative nomenclature (Ch1-Ch6).

artículo científico publicado en 1983

Cerebral Amyloid Angiopathy and Neuritic Plaque Pathology Correlate with Cognitive Decline in Elderly Non-Demented Individuals

artículo científico publicado en 2019

Cerebrospinal Fluid proNGF: A Putative Biomarker for Early Alzheimer's Disease

artículo científico publicado en 2016

Characterization and localization of galanin receptors in human entorhinal cortex ⬇️

artículo científico publicado el 27 de febrero de 1998

Choline acetyltransferase-like immunoreactivity in the forebrain of the red-eared pond turtle (Pseudemys scripta elegans).

artículo científico publicado en 1984

Cholinergic forebrain degeneration in the APPswe/PS1DeltaE9 transgenic mouse.

artículo científico publicado en 2007

Cholinergic innervation in the human hippocampal formation including the entorhinal cortex

artículo científico publicado en 1994

Cholinergic innervation of cortex by the basal forebrain: cytochemistry and cortical connections of the septal area, diagonal band nuclei, nucleus basalis (substantia innominata), and hypothalamus in the rhesus monkey

artículo científico publicado en 1983

Cholinergic plasticity in hippocampus of individuals with mild cognitive impairment: correlation with Alzheimer's neuropathology.

artículo científico publicado en 2003

Cholinergic profiles in the Goettingen miniature pig (Sus scrofa domesticus) brain

artículo científico publicado en 2016

Cholinergic projections from the parabigeminal nucleus (Ch8) to the superior colliculus in the mouse: a combined analysis of horseradish peroxidase transport and choline acetyltransferase immunohistochemistry

artículo científico publicado en 1986

Cholinergic system during the progression of Alzheimer's disease: therapeutic implications

artículo científico publicado en 2008

Cholinergic systems in mammalian brain identified with antibodies against choline acetyltransferase

artículo científico publicado en 1984

Cholinotrophic basal forebrain system alterations in 3xTg-AD transgenic mice

artículo científico publicado en 2010

Cholinotrophic molecular substrates of mild cognitive impairment in the elderly.

artículo científico publicado en 2007

Circuit-specific alterations of N-methyl-D-aspartate receptor subunit 1 in the dentate gyrus of aged monkeys

artículo científico publicado en 1996

Clinicopathological findings following intraventricular glial-derived neurotrophic factor treatment in a patient with Parkinson's disease

artículo científico publicado en 1999

Cognitive Domain Dispersion Association with Alzheimer's Disease Pathology.

artículo científico publicado en 2017

Cognitive Impairment, Neuroimaging, and Alzheimer Neuropathology in Mouse Models of Down Syndrome.

artículo científico publicado en 2016

Cognitive composite score association with Alzheimer's disease plaque and tangle pathology

scholarly article by Michael Malek-Ahmadi et al published 11 September 2018 in Alzheimers Research & Therapy

Cognitive performance correlates with cortical isopeptide immunoreactivity as well as Alzheimer type pathology

scientific article published on 01 February 2008

Connections of the hippocampal formation in humans: II. The endfolial fiber pathway ⬇️

artículo científico publicado el 1 de septiembre de 1997

Contribution of changes in ubiquitin and myelin basic protein to age-related cognitive decline

artículo científico publicado en 2004

Cortical M1 receptor concentration increases without a concomitant change in function in Alzheimer's disease

artículo científico publicado en 2010

Cortical alpha7 nicotinic acetylcholine receptor and beta-amyloid levels in early Alzheimer disease.

artículo científico publicado en 2009

Cortical effects of neurotoxic damage to the nucleus basalis in rats: persistent loss of extrinsic cholinergic input and lack of transsynaptic effect upon the number of somatostatin-containing, cholinesterase-positive, and cholinergic cortical neuro

artículo científico publicado en 1987

Cortical projections arising from the basal forebrain: a study of cholinergic and noncholinergic components employing combined retrograde tracing and immunohistochemical localization of choline acetyltransferase

artículo científico publicado en 1984

Cortical pyroglutamate amyloid-β levels and cognitive decline in Alzheimer's disease.

artículo científico publicado en 2014

DHA diet reduces AD pathology in young APPswe/PS1 Delta E9 transgenic mice: possible gender effects

artículo científico publicado en 2010

Decreased brain-derived neurotrophic factor depends on amyloid aggregation state in transgenic mouse models of Alzheimer's disease.

artículo científico publicado en 2009

Decreased trkA gene expression within basal forebrain neurons in Alzheimer's disease.

artículo científico publicado en 1996

Decreases in soluble alpha-synuclein in frontal cortex correlate with cognitive decline in the elderly

artículo científico publicado en 2004

Delivery of trophic factors to the primate brain

artículo científico publicado en 1993

Demonstrating immune-related antigens in Alzheimer's disease brain tissue

artículo científico publicado en 1990

Diagnosis of Alzheimer's disease. Evaluation of senile plaques of the diffuse type

artículo científico publicado el 11 de enero de 1992

Differential expression of synaptic proteins in the frontal and temporal cortex of elderly subjects with mild cognitive impairment

artículo científico publicado en 2006

Dimebon alters hippocampal amyloid pathology in 3xTg-AD mice ⬇️

artículo científico publicado el 20 de septiembre de 2012

Dissociation of galaninergic and neurotrophic plasticity in Down syndrome and Alzheimer disease

artículo científico publicado en 1995

Distribution and retrograde transport of trophic factors in the central nervous system: functional implications for the treatment of neurodegenerative diseases

artículo científico publicado en 1999

Distribution of high affinity choline transporter immunoreactivity in the primate central nervous system

artículo científico publicado en 2003

Distribution of neurotensin immunoreactivity within the human amygdaloid complex: a comparison with acetylcholinesterase- and Nissl-stained tissue sections

artículo científico publicado en 1992

Dopamine transporter-immunoreactive neurons decrease with age in the human substantia nigra

artículo científico publicado en 1999

Down regulation of trk but not p75NTR gene expression in single cholinergic basal forebrain neurons mark the progression of Alzheimer's disease

artículo científico publicado en 2006

Down-regulation of trkA mRNA within nucleus basalis neurons in individuals with mild cognitive impairment and Alzheimer's disease

artículo científico publicado en 2001

Early Alzheimer's disease-type pathology in the frontal cortex of wild mountain gorillas (Gorilla beringei beringei).

artículo científico publicado en 2015

Ectopic galanin expression and normal galanin receptor 2 and galanin receptor 3 mRNA levels in the forebrain of galanin transgenic mice

artículo científico publicado en 2005

Effect of Neocortical and Hippocampal Amyloid Deposition upon Galaninergic and Cholinergic Neurites in AβPPswe/PS1ΔE9 Mice ⬇️

artículo científico publicado el 1 de enero de 2011

Effects of Maternal Choline Supplementation on the Septohippocampal Cholinergic System in the Ts65Dn Mouse Model of Down Syndrome

artículo científico publicado en 2015

Effects of aromatase inhibition versus gonadectomy on hippocampal complex amyloid pathology in triple transgenic mice ⬇️

artículo científico publicado el 16 de septiembre de 2011

Effects of estrogen replacement therapy on cholinergic basal forebrain neurons and cortical cholinergic innervation in young and aged ovariectomized rhesus monkeys

artículo científico publicado en 2004

Endogenous Galanin Protects Mouse Hippocampal Neurons Against Amyloid Toxicity in vitro via Activation of Galanin Receptor-2 ⬇️

artículo científico publicado el 1 de enero de 2011

Entorhinal cortex beta-amyloid load in individuals with mild cognitive impairment

artículo científico publicado en 1999

Epidermal growth factor receptor expression in demented elderly: localization to vascular endothelial cells of brain, pituitary and skin

artículo científico publicado en 1993

Estrogen receptor alpha containing neurons in the monkey forebrain: lack of association with calcium binding proteins and choline acetyltransferase

artículo científico publicado en 2004

Estrogen receptor immunoreactivity within subregions of the rat forebrain: neuronal distribution and association with perikarya containing choline acetyltransferase

artículo científico publicado en 1999

Evidence for Alzheimer's disease-linked synapse loss and compensation in mouse and human hippocampal CA1 pyramidal neurons.

artículo científico publicado en 2014

Evidence for Mitochondrial UPR Gene Activation in Familial and Sporadic Alzheimer's Disease

artículo científico publicado en 2015

Evidence for a neuroprotective microRNA pathway in amnestic mild cognitive impairment

artículo científico publicado en 2015

Evidence that transmitter-containing dystrophic neurites precede paired helical filament and Alz-50 formation within senile plaques in the amygdala of nondemented elderly and patients with Alzheimer's disease

artículo científico publicado en 1993

Evidence that transmitter-containing dystrophic neurites precede those containing paired helical filaments within senile plaques in the entorhinal cortex of nondemented elderly and Alzheimer's disease patients ⬇️

artículo científico publicado el 13 de agosto de 1993

Excitotoxic and metabolic damage to the rodent striatum: role of the P75 neurotrophin receptor and glial progenitors

artículo científico publicado en 2002

Exosome release and cargo in Down syndrome

artículo científico publicado en 2019

Expression profiling of precuneus layer III cathepsin D-immunopositive pyramidal neurons in mild cognitive impairment and Alzheimer's disease: Evidence for neuronal signaling vulnerability

scientific article published on 22 April 2020

Fetal nigral grafts survive and mediate clinical benefit in a patient with Parkinson's disease ⬇️

artículo científico publicado el 1 de mayo de 1998

Frontal Cortex Epigenetic Dysregulation During the Progression of Alzheimer's Disease

artículo científico publicado en 2018

Frontal Cortex and Hippocampal γ-Secretase Activating Protein Levels in Prodromal Alzheimer Disease

artículo científico publicado en 2017

Frontal cortex and striatal cellular and molecular pathobiology in individuals with Down syndrome with and without dementia

scientific article published on 07 February 2019

Frontal cortex chitinase and pentraxin neuroinflammatory alterations during the progression of Alzheimer's disease

artículo científico publicado en 2020

Functional fetal nigral grafts in a patient with Parkinson's disease: chemoanatomic, ultrastructural, and metabolic studies

artículo científico publicado en 1996

Further understanding the connection between Alzheimer's disease and Down syndrome

artículo científico publicado en 2020

Galanin expression within the basal forebrain in Alzheimer's disease. Comments on therapeutic potential

artículo científico publicado en 1998

Galanin fiber hyperinnervation preserves neuroprotective gene expression in cholinergic basal forebrain neurons in Alzheimer's disease.

artículo científico publicado en 2009

Galanin fiber hypertrophy within the cholinergic nucleus basalis during the progression of Alzheimer's disease.

artículo científico publicado en 2006

Galanin hyperinnervation upregulates choline acetyltransferase expression in cholinergic basal forebrain neurons in Alzheimer's disease.

artículo científico publicado en 2008

Galanin immunoreactivity in the primate central nervous system

artículo científico publicado el 22 de mayo de 1992

Galanin immunoreactivity within the primate basal forebrain: evolutionary change between monkeys and apes

artículo científico publicado en 1993

Galanin in Alzheimer disease

artículo científico publicado en 2003

Galanin in Alzheimer's disease: neuroinhibitory or neuroprotective?

artículo científico publicado en 2008

Galanin inhibits tyrosine hydroxylase expression in midbrain dopaminergic neurons

artículo científico publicado en 2002

Galanin overexpressing transgenic mice

artículo científico publicado en 2002

Galanin plasticity in the cholinergic basal forebrain in Alzheimer's disease and transgenic mice

artículo científico publicado en 2005

Galanin receptor plasticity within the nucleus basalis in early and late Alzheimer's disease: an in vitro autoradiographic analysis

scientific article published on 01 June 2000

Galanin regulates the postnatal survival of a subset of basal forebrain cholinergic neurons

artículo científico publicado en 2000

Galanin transgenic mice display cognitive and neurochemical deficits characteristic of Alzheimer's disease.

artículo científico publicado en 2001

Galanin-like immunoreactivity within the primate basal forebrain: differential staining patterns between humans and monkeys

artículo científico publicado en 1990

Galanin: neurobiologic mechanisms and therapeutic potential for Alzheimer's disease.

artículo científico publicado en 2001

Galaninergic innervation of the cholinergic vertical limb of the diagonal band (Ch2) and bed nucleus of the stria terminalis in aging, Alzheimer's disease and Down's syndrome.

artículo científico publicado en 1993

Gender differences in neurotrophin and glutamate receptor expression in cholinergic nucleus basalis neurons during the progression of Alzheimer's disease ⬇️

artículo científico publicado el 17 de marzo de 2011

Gene Profiling of Nucleus Basalis Tau Containing Neurons in Chronic Traumatic Encephalopathy: A Chronic Effects of Neurotrauma Consortium Study

artículo científico publicado en 2018

Gene expression profiles of cholinergic nucleus basalis neurons in Alzheimer's disease.

artículo científico publicado en 2002

Grafts of EGF-responsive neural stem cells derived from GFAP-hNGF transgenic mice: trophic and tropic effects in a rodent model of Huntington's disease.

artículo científico publicado en 1997

HDAC2 dysregulation in the nucleus basalis of Meynert during the progression of Alzheimer's disease

scientific article published on 28 October 2018

Hippocampal Drebrin Loss in Mild Cognitive Impairment ⬇️

artículo científico publicado el 4 de febrero de 2012

Hippocampal ProNGF Signaling Pathways and β-Amyloid Levels in Mild Cognitive Impairment and Alzheimer Disease ⬇️

artículo científico publicado el 1 de noviembre de 2012

Hippocampal endosomal, lysosomal, and autophagic dysregulation in mild cognitive impairment: correlation with aβ and tau pathology

artículo científico publicado en 2015

Hippocampal plasticity during the progression of Alzheimer's disease

artículo científico publicado en 2015

Hippocampal synaptic loss in early Alzheimer's disease and mild cognitive impairment

artículo científico publicado en 2005

Human cholinergic basal forebrain: chemoanatomy and neurologic dysfunction.

artículo científico publicado en 2003

Human orbitofrontal cortex: cytoarchitecture and quantitative immunohistochemical parcellation

artículo científico publicado en 1995

Immunocytochemical distribution of peptidergic and cholinergic fibers in the human amygdala: their depletion in Alzheimer's disease and morphologic alteration in non-demented elderly with numerous senile plaques.

artículo científico publicado en 1993

Immunocytochemical localization of the dopamine transporter in human brain

artículo científico publicado en 1999

Immunohistochemical evidence for a possible somatostatin-containing amygdalostriatal pathway in normal and Alzheimer's disease brain.

artículo científico publicado en 1988

Impact of age on acute post-TBI neuropathology in mice expressing humanized tau: a Chronic Effects of Neurotrauma Consortium Study

artículo científico publicado en 2018

Improved detection of substantia nigra pathology in Alzheimer's disease

artículo científico publicado en 2002

Inability of plasma and urine F2A-isoprostane levels to differentiate mild cognitive impairment from Alzheimer's disease

artículo científico publicado en 2010

Increased matrix metalloproteinase 9 activity in mild cognitive impairment

artículo científico publicado en 2009

Increased number of NADPH-d-positive neurons within the substantia innominata in Alzheimer's disease

artículo científico publicado en 1995

Increased proNGF levels in subjects with mild cognitive impairment and mild Alzheimer disease

artículo científico publicado en 2004

Insula of the old world monkey. I. Architectonics in the insulo-orbito-temporal component of the paralimbic brain

artículo científico publicado en 1982

Insula of the old world monkey. II: Afferent cortical input and comments on the claustrum

artículo científico publicado en 1982

Insula of the old world monkey. III: Efferent cortical output and comments on function

artículo científico publicado en 1982

Insular interconnections with the amygdala in the rhesus monkey

artículo científico publicado en 1981

Intranasal Delivery of NEMO-Binding Domain Peptide Prevents Memory Loss in a Mouse Model of Alzheimer's Disease

artículo científico publicado en 2015

Intrastriatal Infusions of Brain-Derived Neurotrophic Factor: Retrograde Transport and Colocalization with Dopamine Containing Substantia Nigra Neurons in Rat ⬇️

artículo científico publicado el 1 de septiembre de 1994

Intrastriatal and intraventricular infusion of brain-derived neurotrophic factor in the cynomologous monkey: distribution, retrograde transport and co-localization with substantia nigra dopamine-containing neurons

artículo científico publicado en 1996

Intrastriatal implants of polymer encapsulated cells genetically modified to secrete human nerve growth factor: trophic effects upon cholinergic and noncholinergic striatal neurons

artículo científico publicado en 1996

Intravenous immunoglobulin (IVIG) treatment exerts antioxidant and neuropreservatory effects in preclinical models of Alzheimer's disease

artículo científico publicado en 2014

Intravenous immunoglobulin reduces tau pathology and preserves neuroplastic gene expression in the 3xTg mouse model of Alzheimer's disease.

artículo científico publicado en 2014

Lack of neocortical nerve cell loss in Alzheimer's disease: reality or methodological artifact

artículo científico publicado en 1994

Locus coeruleus cellular and molecular pathology during the progression of Alzheimer's disease

artículo científico publicado en 2017

Loss and atrophy of layer II entorhinal cortex neurons in elderly people with mild cognitive impairment

artículo científico publicado en 2001

Loss of basal forebrain P75(NTR) immunoreactivity in subjects with mild cognitive impairment and Alzheimer's disease

artículo científico publicado en 2002

Loss of developing cholinergic basal forebrain neurons following excitotoxic lesions of the hippocampus: rescue by neurotrophins

artículo científico publicado en 1994

Loss of nerve growth factor receptor-containing neurons in Alzheimer's disease: a quantitative analysis across subregions of the basal forebrain

artículo científico publicado en 1989

Loss of nucleus basalis neurons containing trkA immunoreactivity in individuals with mild cognitive impairment and early Alzheimer's disease

artículo científico publicado en 2000

Loss of precuneus dendritic spines immunopositive for spinophilin is related to cognitive impairment in early Alzheimer's disease.

artículo científico publicado en 2017

Maternal Choline Supplementation Alters Basal Forebrain Cholinergic Neuron Gene Expression in the Ts65Dn Mouse Model of Down Syndrome

artículo científico publicado en 2019

Maternal Choline Supplementation: A Potential Prenatal Treatment for Down Syndrome and Alzheimer's Disease.

artículo científico publicado en 2015

Maternal choline supplementation differentially alters the basal forebrain cholinergic system of young-adult Ts65Dn and disomic mice.

artículo científico publicado en 2014

Maternal choline supplementation improves spatial learning and adult hippocampal neurogenesis in the Ts65Dn mouse model of Down syndrome

artículo científico publicado en 2013

Maternal choline supplementation improves spatial mapping and increases basal forebrain cholinergic neuron number and size in aged Ts65Dn mice

artículo científico publicado en 2014

Maternal choline supplementation in a mouse model of Down syndrome: Effects on attention and nucleus basalis/substantia innominata neuron morphology in adult offspring

artículo científico publicado en 2016

Microarray analysis of hippocampal CA1 neurons implicates early endosomal dysfunction during Alzheimer's disease progression

artículo científico publicado en 2010

Microglia changes associated to Alzheimer's disease pathology in aged chimpanzees

artículo científico publicado en 2018

Mild cognitive impairment: pathology and mechanisms.

artículo científico publicado en 2011

Molecular and cellular pathophysiology of preclinical Alzheimer's disease

artículo científico publicado en 2016

NGF and Alzheimer's disease: unfulfilled promise and untapped potential

artículo científico publicado en 1989

NGF receptor (p75)-immunoreactivity in the developing primate basal ganglia

artículo científico publicado en 1993

NGF receptor gene expression is decreased in the nucleus basalis in Alzheimer's disease

artículo científico publicado en 1989

Nanoparticle-based detection in cerebral spinal fluid of a soluble pathogenic biomarker for Alzheimer's disease

artículo científico publicado en 2005

Negative Impact of Female Sex on Outcomes from Repetitive Mild Traumatic Brain Injury in hTau Mice Is Age Dependent: A Chronic Effects of Neurotrauma Consortium Study

artículo científico publicado en 2017

Neocortical and hippocampal TREM2 protein levels during the progression of Alzheimer's disease.

artículo científico publicado en 2017

Nerve Growth Factor Pathobiology During the Progression of Alzheimer's Disease

scientific article published on 01 July 2019

Nerve growth factor in Alzheimerʼs disease: defective retrograde transport to nucleus basalis ⬇️

artículo científico publicado el 9 de mayo de 1995

Nerve growth factor receptor and choline acetyltransferase remain colocalized in the nucleus basalis (Ch4) of Alzheimer's patients

artículo científico publicado en 1989

Nerve growth factor receptor expressing human basal forebrain neurons: pathologic alterations in Alzheimer's and Parkinson's disease

artículo científico publicado en 1989

Nerve growth factor receptor immunoreactive profiles in the normal, aged human basal forebrain: colocalization with cholinergic neurons

artículo científico publicado en 1989

Nerve growth factor receptor immunoreactivity in the new world monkey (Cebus apella) and human cerebellum

artículo científico publicado en 1991

Nerve growth factor receptor-immunoreactive neurons within the developing human cortex

artículo científico publicado en 1992

Nerve growth factor-like immunoreactive profiles in the primate basal forebrain and hippocampal formation

artículo científico publicado en 1994

Neural inputs into the temporopolar cortex of the rhesus monkey

artículo científico publicado en 1987

Neural transplants in patients with Huntington's disease undergo disease-like neuronal degeneration

artículo científico publicado en 2009

Neuritic and Diffuse Plaque Associations with Memory in Non-Cognitively Impaired Elderly

artículo científico publicado en 2016

Neurofibrillary tangles in cholinergic pedunculopontine neurons in Alzheimer's disease.

artículo científico publicado en 1988

Neuron loss associated with age but not Alzheimer's disease pathology in the chimpanzee brain

scientific article published on 21 September 2020

Neuronal LR11 Expression Does Not Differentiate between Clinically-Defined Alzheimer's Disease and Control Brains ⬇️

artículo científico publicado el 21 de agosto de 2012

Neuronal LR11/sorLA expression is reduced in mild cognitive impairment

artículo científico publicado en 2007

Neuronal exosomes reveal Alzheimer's disease biomarkers in Down syndrome

artículo científico publicado en 2016

Neuronal gene expression profiling: uncovering the molecular biology of neurodegenerative disease.

artículo científico publicado en 2006

Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein

artículo científico publicado en 2005

Neuropathological correlates of amyloid PET imaging in Down syndrome

artículo científico publicado en 2019

Neuropathological evidence of graft survival and striatal reinnervation after the transplantation of fetal mesencephalic tissue in a patient with Parkinson's disease

artículo científico publicado en 1995

Neuropathology of mice carrying mutant APP(swe) and/or PS1(M146L) transgenes: alterations in the p75(NTR) cholinergic basal forebrain septohippocampal pathway

artículo científico publicado en 2001

Neuroprotective Role for Galanin in Alzheimer’s Disease ⬇️

artículo científico publicado el 1 de enero de 2010

Nigrostriatal dysfunction in familial Alzheimer's disease-linked APPswe/PS1DeltaE9 transgenic mice.

artículo científico publicado en 2005

Noradrenaline activation of neurotrophic pathways protects against neuronal amyloid toxicity

artículo científico publicado en 2010

Nurr1 in Parkinson's disease and related disorders

artículo científico publicado en 2006

Oxidative stress and hippocampal synaptic protein levels in elderly cognitively intact individuals with Alzheimer's disease pathology

artículo científico publicado en 2016

PUTATIVE CSF PROTEIN BIOMARKER CANDIDATES FOR AMNESTIC MILD COGNITIVE IMPAIRMENT

artículo científico publicado en 2010

Parahippocampal tau pathology in healthy aging, mild cognitive impairment, and early Alzheimer's disease

artículo científico publicado en 2002

Parvalbumin-immunoreactive neurons in the hippocampal formation of Alzheimer's diseased brain ⬇️

artículo científico publicado el 1 de octubre de 1997

Precuneus amyloid burden is associated with reduced cholinergic activity in Alzheimer disease.

artículo científico publicado en 2011

Precursor form of brain-derived neurotrophic factor and mature brain-derived neurotrophic factor are decreased in the pre-clinical stages of Alzheimer's disease.

artículo científico publicado en 2005

Prefibrillar tau oligomers in mild cognitive impairment and Alzheimer's disease

artículo científico publicado en 2013

Presenilin-1 protein expression in familial and sporadic Alzheimer's disease

artículo científico publicado en 1997

Preservation of brain nerve growth factor in mild cognitive impairment and Alzheimer disease

artículo científico publicado en 2003

Preservation of cortical sortilin protein levels in MCI and Alzheimer's disease.

artículo científico publicado en 2010

Preservation of nucleus basalis neurons containing choline acetyltransferase and the vesicular acetylcholine transporter in the elderly with mild cognitive impairment and early Alzheimer's disease

artículo científico publicado en 1999

Pretangle pathology within cholinergic nucleus basalis neurons coincides with neurotrophic and neurotransmitter receptor gene dysregulation during the progression of Alzheimer's disease.

artículo científico publicado en 2018

Primum non nocere: a call for balance when reporting on CTE

artículo científico publicado en 2019

Progression of tau pathology in cholinergic Basal forebrain neurons in mild cognitive impairment and Alzheimer's disease

artículo científico publicado en 2011

Progression of tau pathology within cholinergic nucleus basalis neurons in chronic traumatic encephalopathy: A chronic effects of neurotrauma consortium study

artículo científico publicado en 2016

Protein homeostasis gene dysregulation in pretangle-bearing nucleus basalis neurons during the progression of Alzheimer's disease

artículo científico publicado en 2016

RNA amplification of bromodeoxyuridine labeled newborn neurons in the monkey hippocampus

artículo científico publicado en 2004

Rac1b increases with progressive tau pathology within cholinergic nucleus basalis neurons in Alzheimer's disease.

artículo científico publicado en 2011

Reduced nicotinamide adenine dinucleotide phosphate-diaphorase (NADPH-d) histochemistry in the hippocampal formation of the New World monkey (Saimiri sciureus).

artículo científico publicado en 1990

Reduced nicotinamide adenine dinucleotide phosphate-diaphorase/nitric oxide synthase profiles in the human hippocampal formation and perirhinal cortex

scientific article published on 01 July 1995

Reduction in TrkA-immunoreactive neurons is not associated with an overexpression of galaninergic fibers within the nucleus basalis in Down's syndrome

artículo científico publicado en 2000

Reduction in p140-TrkA Receptor Protein within the Nucleus Basalis and Cortex in Alzheimer's Disease ⬇️

artículo científico publicado el 1 de julio de 1997

Reduction of choline acetyltransferase activity in primary visual cortex in mild to moderate Alzheimer's disease

artículo científico publicado en 2005

Reduction of cortical TrkA but not p75(NTR) protein in early-stage Alzheimer's disease.

artículo científico publicado en 2004

Reduction of neurotensin immunoreactivity in the amygdala in Alzheimer's disease

artículo científico publicado en 1990

Regional binding of tau and amyloid PET tracers in Down syndrome autopsy brain tissue

artículo científico publicado en 2020

Regional selectivity of rab5 and rab7 protein upregulation in mild cognitive impairment and Alzheimer's disease

artículo científico publicado en 2010

Regional variations in cortical cholinergic innervation: chemoarchitectonics of acetylcholinesterase-containing fibers in the macaque brain

artículo científico publicado en 1984

Regulator of Cell Cycle (RGCC) Expression During the Progression of Alzheimer's Disease

artículo científico publicado en 2016

Resilience of precuneus neurotrophic signaling pathways despite amyloid pathology in prodromal Alzheimer's disease

artículo científico publicado en 2014

Retrograde transport of brain-derived neurotrophic factor (BDNF) following infusion in neo- and limbic cortex in rat: relationship to BDNF mRNA expressing neurons

artículo científico publicado en 1996

Selective decline of neurotrophin and neurotrophin receptor genes within CA1 pyramidal neurons and hippocampus proper: Correlation with cognitive performance and neuropathology in mild cognitive impairment and Alzheimer's disease

artículo científico publicado en 2017

Selective disruption of TLR2-MyD88 interaction inhibits inflammation and attenuates Alzheimer's pathology

artículo científico publicado en 2018

Selective inhibition of NF-kappaB activation prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease

artículo científico publicado en 2007

Sex Steroid Levels and AD‐Like Pathology in 3xTgAD Mice ⬇️

artículo científico publicado el 1 de febrero de 2013

Sex differences in the cholinergic basal forebrain in the Ts65Dn mouse model of Down syndrome and Alzheimer's disease.

artículo científico publicado en 2013

Shift in the ratio of three-repeat tau and four-repeat tau mRNAs in individual cholinergic basal forebrain neurons in mild cognitive impairment and Alzheimer's disease

artículo científico publicado en 2006

Single cell gene expression profiling in Alzheimer's disease

artículo científico publicado en 2006

Single-cell gene expression analysis: implications for neurodegenerative and neuropsychiatric disorders.

artículo científico publicado en 2004

Some observations on the course and composition of the cingulum bundle in the rhesus monkey

artículo científico publicado en 1984

Staging of Alzheimer's pathology in triple transgenic mice: a light and electron microscopic analysis

artículo científico publicado en 2010

Static and Dynamic Cognitive Reserve Proxy Measures: Interactions with Alzheimer's Disease Neuropathology and Cognition

artículo científico publicado en 2017

Statistical considerations for assessing cognition and neuropathology associations in preclinical Alzheimer's disease

scholarly article published January 2017

Striatal extracts from patients with Parkinson's disease promote dopamine neuron growth in mesencephalic cultures

artículo científico publicado en 1993

Superior frontal cortex cholinergic axon density in mild cognitive impairment and early Alzheimer disease.

artículo científico publicado en 2007

Synapse stability in the precuneus early in the progression of Alzheimer's disease

artículo científico publicado en 2013

Synaptic Loss in the Inferior Temporal Gyrus in Mild Cognitive Impairment and Alzheimer's Disease ⬇️

artículo científico publicado el 1 de enero de 2011

Synaptic alterations in CA1 in mild Alzheimer disease and mild cognitive impairment.

artículo científico publicado en 2007

Synaptic change in the posterior cingulate gyrus in the progression of Alzheimer's disease

artículo científico publicado en 2015

Synaptic gene dysregulation within hippocampal CA1 pyramidal neurons in mild cognitive impairment.

artículo científico publicado en 2013

Systematic regional differences in the cholinergic innervation of the primate cerebral cortex: distribution of enzyme activities and some behavioral implications

artículo científico publicado en 1986

TRK and p75 neurotrophin receptor systems in the developing human brain

scientific article published on 01 June 1996

Tau Oligomer Pathology in Nucleus Basalis Neurons During the Progression of Alzheimer Disease

artículo científico publicado en 2018

Tau in situ hybridization in normal and Alzheimer brain: localization in the somatodendritic compartment.

artículo científico publicado en 1989

Tau pathology in the medial temporal lobe of athletes with chronic traumatic encephalopathy: a chronic effects of neurotrauma consortium study

scientific article published on 12 December 2019

Tau-66: evidence for a novel tau conformation in Alzheimer's disease

artículo científico publicado en 2001

Telomeric Alterations in the Default Mode Network during the Progression of Alzheimer's disease: Selective Vulnerability of the Precuneus

artículo científico publicado en 2020

Tenascin-C Is Associated with Cored Amyloid-β Plaques in Alzheimer Disease and Pathology Burdened Cognitively Normal Elderly

artículo científico publicado en 2016

Thalamic connections of the insula in the rhesus monkey and comments on the paralimbic connectivity of the medial pulvinar nucleus

artículo científico publicado en 1984

The aged monkey basal forebrain: rescue and sprouting of axotomized basal forebrain neurons after grafts of encapsulated cells secreting human nerve growth factor

artículo científico publicado en 1994

The amyloid precursor protein is concentrated in neuronal lysosomes in normal and Alzheimer disease subjects.

artículo científico publicado en 1989

The role of nerve growth factor receptors in cholinergic basal forebrain degeneration in prodromal Alzheimer disease

artículo científico publicado en 2005

Three-dimensional representation and cortical projection topography of the nucleus basalis (Ch4) in the macaque: concurrent demonstration of choline acetyltransferase and retrograde transport with a stabilized tetramethylbenzidine method for horsera

artículo científico publicado en 1986

TrkA-immunoreactive profiles in the central nervous system: colocalization with neurons containing p75 nerve growth factor receptor, choline acetyltransferase, and serotonin

artículo científico publicado en 1994

Trophic regulation of basal forebrain gene expression in aging and Alzheimer's disease

artículo científico publicado en 1990

Tyrosine kinase A, galanin and nitric oxide synthase within basal forebrain neurons in the rat ⬇️

artículo científico publicado el 1 de noviembre de 1998

U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer's disease

artículo científico publicado en 2013

U1 small nuclear ribonucleoproteins (snRNPs) aggregate in Alzheimer's disease due to autosomal dominant genetic mutations and trisomy 21.

artículo científico publicado en 2014

Upregulation of choline acetyltransferase activity in hippocampus and frontal cortex of elderly subjects with mild cognitive impairment.

artículo científico publicado en 2002

Upregulation of select rab GTPases in cholinergic basal forebrain neurons in mild cognitive impairment and Alzheimer's disease.

artículo científico publicado en 2011

m2 muscarinic acetylcholine receptor-immunoreactive neurons are not reduced within the nucleus basalis in Alzheimer's disease: Relationship with cholinergic and galaninergic perikarya ⬇️

artículo científico publicado el 16 de marzo de 1998

p75 nerve growth factor receptor immunoreactivity in the human brainstem and spinal cord

artículo científico publicado en 1992

trk-immunoreactivity in the monkey central nervous system: forebrain

artículo científico publicado en 1994

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