Lista de obras -

2-Substituted-2-amino-6-boronohexanoic acids as arginase inhibitors

artículo científico publicado en 2013

Benzoxazepine-Derived Selective, Orally Bioavailable Inhibitor of Human Acidic Mammalian Chitinase

scientific article published on 24 April 2020

Boronic acid-based arginase inhibitors in cancer immunotherapy

scientific article published on 23 July 2020

Development of Dual Chitinase Inhibitors as Potential New Treatment for Respiratory System Diseases

scientific article published on 23 July 2019

Development of N-2,4-pyrimidine-N-phenyl-N'-alkyl ureas as orally active inhibitors of tumor necrosis factor alpha (TNF-alpha) synthesis. Part 2

artículo científico publicado en 2006

Development of N-2,4-pyrimidine-N-phenyl-N'-phenyl ureas as inhibitors of tumor necrosis factor alpha (TNF-alpha) synthesis. Part 1

artículo científico publicado en 2006

Development of N-4,6-pyrimidine-N-alkyl-N'-phenyl ureas as orally active inhibitors of lymphocyte specific tyrosine kinase

artículo científico publicado en 2006

Development of new pyrrolopyrimidine-based inhibitors of Janus kinase 3 (JAK3).

artículo científico publicado en 2006

Development of orally bioavailable bicyclic pyrazolones as inhibitors of tumor necrosis factor-alpha production

artículo científico publicado en 2004

Discovery and Pharmacokinetics of Sulfamides and Guanidines as Potent Human Arginase 1 Inhibitors

scientific article published on 13 March 2020

Discovery of (R)-2-amino-6-borono-2-(2-(piperidin-1-yl)ethyl)hexanoic acid and congeners as highly potent inhibitors of human arginases I and II for treatment of myocardial reperfusion injury

artículo científico publicado en 2013

Discovery of OATD-01, a First-in-Class Chitinase Inhibitor as Potential New Therapeutics for Idiopathic Pulmonary Fibrosis

artículo científico publicado en 2020

Discovery of selective, orally bioavailable inhibitor of mouse chitotriosidase

artículo científico publicado en 2017

Lead compounds discovered from libraries: part 2.

artículo científico publicado en 2003

Solid-supported synthesis of putative peptide beta-turn mimetics via Ugi reaction for diketopiperazine formation

artículo científico publicado en 2002

Synthesis of quaternary α-amino acid-based arginase inhibitors via the Ugi reaction

artículo científico publicado en 2013

Targeting Acidic Mammalian chitinase Is Effective in Animal Model of Asthma

artículo científico publicado en 2017

The development of 2-benzimidazole substituted pyrimidine based inhibitors of lymphocyte specific kinase (Lck)

artículo científico publicado en 2006

The development of monocyclic pyrazolone based cytokine synthesis inhibitors

artículo científico publicado en 2005

The development of new bicyclic pyrazole-based cytokine synthesis inhibitors

artículo científico publicado en 2004

The development of new isoxazolone based inhibitors of tumor necrosis factor-alpha (TNF-alpha) production

artículo científico publicado en 2005

The development of novel 1,2-dihydro-pyrimido[4,5-c]pyridazine based inhibitors of lymphocyte specific kinase (Lck)

artículo científico publicado en 2006

The development of novel C-2, C-8, and N-9 trisubstituted purines as inhibitors of TNF-alpha production

artículo científico publicado en 2006

The development of novel inhibitors of tumor necrosis factor-alpha (TNF-alpha) production based on substituted [5,5]-bicyclic pyrazolones

artículo científico publicado en 2004

The synthesis and evaluation of indolylureas as PKCα inhibitors

artículo científico publicado en 2011

Lista de obras de

2-Substituted-2-amino-6-boronohexanoic acids as arginase inhibitors

Benzoxazepine-Derived Selective, Orally Bioavailable Inhibitor of Human Acidic Mammalian Chitinase

Boronic acid-based arginase inhibitors in cancer immunotherapy

Development of Dual Chitinase Inhibitors as Potential New Treatment for Respiratory System Diseases

Development of N-2,4-pyrimidine-N-phenyl-N'-alkyl ureas as orally active inhibitors of tumor necrosis factor alpha (TNF-alpha) synthesis. Part 2

Development of N-2,4-pyrimidine-N-phenyl-N'-phenyl ureas as inhibitors of tumor necrosis factor alpha (TNF-alpha) synthesis. Part 1

Development of N-4,6-pyrimidine-N-alkyl-N'-phenyl ureas as orally active inhibitors of lymphocyte specific tyrosine kinase

Development of new pyrrolopyrimidine-based inhibitors of Janus kinase 3 (JAK3).

Development of orally bioavailable bicyclic pyrazolones as inhibitors of tumor necrosis factor-alpha production

Discovery and Pharmacokinetics of Sulfamides and Guanidines as Potent Human Arginase 1 Inhibitors

Discovery of (R)-2-amino-6-borono-2-(2-(piperidin-1-yl)ethyl)hexanoic acid and congeners as highly potent inhibitors of human arginases I and II for treatment of myocardial reperfusion injury

Discovery of OATD-01, a First-in-Class Chitinase Inhibitor as Potential New Therapeutics for Idiopathic Pulmonary Fibrosis

Discovery of selective, orally bioavailable inhibitor of mouse chitotriosidase

Lead compounds discovered from libraries: part 2.

Solid-supported synthesis of putative peptide beta-turn mimetics via Ugi reaction for diketopiperazine formation

Synthesis of quaternary α-amino acid-based arginase inhibitors via the Ugi reaction

Targeting Acidic Mammalian chitinase Is Effective in Animal Model of Asthma

The development of 2-benzimidazole substituted pyrimidine based inhibitors of lymphocyte specific kinase (Lck)

The development of monocyclic pyrazolone based cytokine synthesis inhibitors

The development of new bicyclic pyrazole-based cytokine synthesis inhibitors

The development of new isoxazolone based inhibitors of tumor necrosis factor-alpha (TNF-alpha) production

The development of novel 1,2-dihydro-pyrimido[4,5-c]pyridazine based inhibitors of lymphocyte specific kinase (Lck)

The development of novel C-2, C-8, and N-9 trisubstituted purines as inhibitors of TNF-alpha production

The development of novel inhibitors of tumor necrosis factor-alpha (TNF-alpha) production based on substituted [5,5]-bicyclic pyrazolones

The synthesis and evaluation of indolylureas as PKCα inhibitors