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A High-Throughput Screen Identifies 2,9-Diazaspiro[5.5]Undecanes as Inducers of the Endoplasmic Reticulum Stress Response with Cytotoxic Activity in 3D Glioma Cell Models

artículo científico publicado en 2016

A serine protease inhibitor prevents endoplasmic reticulum stress-induced cleavage but not transport of the membrane-bound transcription factor ATF6.

artículo científico publicado en 2003

A thrombospondin-dependent pathway for a protective ER stress response

artículo científico publicado en 2012

ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein response

artículo científico

Activation of the ATF6, XBP1 and grp78 genes in human hepatocellular carcinoma: a possible involvement of the ER stress pathway in hepatocarcinogenesis

artículo científico publicado en 2003

An IFN-γ–stimulated ATF6–C/EBP-β–signaling pathway critical for the expression of Death Associated Protein Kinase 1 and induction of autophagy

artículo científico publicado el 13 de junio de 2012

Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation

artículo científico publicado en 2006

Distinct roles of activating transcription factor 6 (ATF6) and double-stranded RNA-activated protein kinase-like endoplasmic reticulum kinase (PERK) in transcription during the mammalian unfolded protein response

artículo científico publicado en 2002

EDEM2 initiates mammalian glycoprotein ERAD by catalyzing the first mannose trimming step

artículo científico publicado en 2014

EDEM2 stably disulfide-bonded to TXNDC11 catalyzes the first mannose trimming step in mammalian glycoprotein ERAD

artículo científico publicado en 2020

Endoplasmic reticulum stress-induced formation of transcription factor complex ERSF including NF-Y (CBF) and activating transcription factors 6alpha and 6beta that activates the mammalian unfolded protein response

artículo científico publicado en 2001

Forcible destruction of severely misfolded mammalian glycoproteins by the non-glycoprotein ERAD pathway

artículo científico publicado en 2015

IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response

artículo científico publicado en 2002

Identification of the G13 (cAMP-response-element-binding protein-related protein) gene product related to activating transcription factor 6 as a transcriptional activator of the mammalian unfolded protein response

artículo científico publicado en 2001

SEL1L Is Required for Endoplasmic Reticulum-associated Degradation of Misfolded Luminal Proteins but not Transmembrane Proteins in Chicken DT40 Cell Line

artículo científico publicado el 20 de agosto de 2011

p31 deficiency influences endoplasmic reticulum tubular morphology and cell survival

scientific journal article