Lista de obras -

A REDD1/TXNIP pro-oxidant complex regulates ATG4B activity to control stress-induced autophagy and sustain exercise capacity.

artículo científico publicado en 2015

A Systematic Comparison of Traditional and Multigene Panel Testing for Hereditary Breast and Ovarian Cancer Genes in More Than 1000 Patients

artículo científico publicado en 2015

A microRNA-dependent circuit controlling p63/p73 homeostasis: p53 family cross-talk meets therapeutic opportunity ⬇️

artículo científico publicado el 1 de marzo de 2011

A microRNA-dependent program controls p53-independent survival and chemosensitivity in human and murine squamous cell carcinoma.

artículo científico publicado en 2011

A mutational signature reveals alterations underlying deficient homologous recombination repair in breast cancer

artículo científico publicado en 2017

A unique subset of glycolytic tumour-propagating cells drives squamous cell carcinoma

artículo científico publicado en 2021

ACTL6A Is Co-Amplified with p63 in Squamous Cell Carcinoma to Drive YAP Activation, Regenerative Proliferation, and Poor Prognosis.

artículo científico publicado en 2016

Aneuploidy and a deregulated DNA damage response suggest haploinsufficiency in breast tissues of BRCA2 mutation carriers

scientific article published on 29 January 2020

BRCA1-Associated Epigenetic Regulation of p73 Mediates an Effector Pathway for Chemosensitivity in Ovarian Carcinoma ⬇️

artículo científico publicado el 31 de agosto de 2010

Basal cell signaling by p63 controls luminal progenitor function and lactation via NRG1.

artículo científico publicado en 2014

Bcl-2 blocks cisplatin-induced apoptosis and predicts poor outcome following chemoradiation treatment in advanced oropharyngeal squamous cell carcinoma

artículo científico publicado en 2009

Bioprinting the Cancer Microenvironment

artículo científico publicado en 2016

Circadian function in cancer: regulating the DNA damage response.

artículo científico publicado en 2011

Circulating oncometabolite 2-hydroxyglutarate is a potential surrogate biomarker in patients with isocitrate dehydrogenase-mutant intrahepatic cholangiocarcinoma

artículo científico publicado en 2014

Comparison of the Genomic Landscape Between Primary Breast Cancer in African American Versus White Women and the Association of Racial Differences With Tumor Recurrence

artículo científico publicado en 2015

Dexamethasone represses signaling through the mammalian target of rapamycin in muscle cells by enhancing expression of REDD1.

artículo científico publicado en 2006

Efficacy of neoadjuvant Cisplatin in triple-negative breast cancer

artículo científico publicado en 2010

FGFR2 signaling underlies p63 oncogenic function in squamous cell carcinoma

artículo científico publicado en 2013

FOXO-regulated transcription restricts overgrowth of Tsc mutant organs

artículo científico publicado en 2008

Frequent Mutation of Isocitrate Dehydrogenase (IDH)1 and IDH2 in Cholangiocarcinoma Identified Through Broad-Based Tumor Genotyping ⬇️

artículo científico publicado el 16 de diciembre de 2011

Growth control under stress: mTOR regulation through the REDD1-TSC pathway

artículo científico publicado en 2005

Hypoxia regulates TSC1/2-mTOR signaling and tumor suppression through REDD1-mediated 14-3-3 shuttling

artículo científico publicado en 2008

Identification of somatically acquired BRCA1/2 mutations by cfDNA analysis in patients with metastatic breast cancer

artículo científico publicado en 2020

Mcl-1 and FBW7 control a dominant survival pathway underlying HDAC and Bcl-2 inhibitor synergy in squamous cell carcinoma.

artículo científico publicado en 2012

Mutation frequency in 15 common cancer genes in high-risk head and neck squamous cell carcinoma

artículo científico publicado en 2014

Mutational analysis and clinical correlation of metastatic colorectal cancer

artículo científico publicado en 2014

Negative feedback control of HIF-1 through REDD1-regulated ROS suppresses tumorigenesis

artículo científico publicado en 2010

Neoadjuvant Endocrine Therapy for Estrogen Receptor-Positive Breast Cancer: A Systematic Review and Meta-analysis.

artículo científico publicado en 2016

PI3K inhibition impairs BRCA1/2 expression and sensitizes BRCA-proficient triple-negative breast cancer to PARP inhibition

scientific article published on 22 August 2012

Physical association of HDAC1 and HDAC2 with p63 mediates transcriptional repression and tumor maintenance in squamous cell carcinoma

artículo científico publicado en 2011

REDD1 loss reprograms lipid metabolism to drive progression of RAS mutant tumors

scientific article published on 09 April 2020

REDD1, a developmentally regulated transcriptional target of p63 and p53, links p63 to regulation of reactive oxygen species

artículo científico publicado en 2002

Rapid targeted mutational analysis of human tumours: a clinical platform to guide personalized cancer medicine

artículo científico publicado en 2010

Reciprocal intraepithelial interactions between TP63 and hedgehog signaling regulate quiescence and activation of progenitor elaboration by mammary stem cells.

artículo científico publicado en 2008

Regulation of gene expression by WT1 in development and tumorigenesis

artículo científico publicado en 2002

Regulation of mTOR and cell growth in response to energy stress by REDD1.

artículo científico publicado en 2005

Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex

artículo científico publicado en 2004

Standardized decision support in next generation sequencing reports of somatic cancer variants

artículo científico

TBCRC009: A Multicenter Phase II Clinical Trial of Platinum Monotherapy With Biomarker Assessment in Metastatic Triple-Negative Breast Cancer

artículo científico publicado en 2015

Targetable signaling pathway mutations are associated with malignant phenotype in IDH-mutant gliomas.

artículo científico publicado en 2014

The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1alpha

scientific journal article

The integrin alpha(v)beta(3-5) ligand MFG-E8 is a p63/p73 target gene in triple-negative breast cancers but exhibits suppressive functions in ER(+) and erbB2(+) breast cancers

artículo científico publicado en 2010

The molecular pathogenesis of head and neck squamous cell carcinoma ⬇️

artículo científico publicado el 1 de junio de 2012

The p63/p73 network mediates chemosensitivity to cisplatin in a biologically defined subset of primary breast cancers

artículo científico publicado en 2007

Tumor-specific p73 up-regulation mediates p63 dependence in squamous cell carcinoma

artículo científico publicado en 2006

Women's Health Issues for BRCA Mutation Carriers

artículo científico publicado en 2016

Yap tunes airway epithelial size and architecture by regulating the identity, maintenance, and self-renewal of stem cells

artículo científico publicado en 2014

Young adult daughters of BRCA1/2 positive mothers: what do they know about hereditary cancer and how much do they worry?

artículo científico publicado en 2013

mTOR Activity Under Hypoxia ⬇️

artículo científico publicado el 1 de enero de 2012

p63 and p73: life and death in squamous cell carcinoma

artículo científico publicado en 2006

p63 mediates survival in squamous cell carcinoma by suppression of p73-dependent apoptosis

artículo científico publicado en 2006

p63 regulates an adhesion programme and cell survival in epithelial cells

artículo científico publicado en 2006

ΔNp63α Silences a miRNA Program to Aberrantly Initiate a Wound-Healing Program That Promotes TGFβ-Induced Metastasis

artículo científico publicado en 2016

ΔNp63α represses anti-proliferative genes via H2A.Z deposition.

artículo científico publicado en 2012

Lista de obras de

A REDD1/TXNIP pro-oxidant complex regulates ATG4B activity to control stress-induced autophagy and sustain exercise capacity.

A Systematic Comparison of Traditional and Multigene Panel Testing for Hereditary Breast and Ovarian Cancer Genes in More Than 1000 Patients

A microRNA-dependent circuit controlling p63/p73 homeostasis: p53 family cross-talk meets therapeutic opportunity ⬇️

A microRNA-dependent program controls p53-independent survival and chemosensitivity in human and murine squamous cell carcinoma.

A mutational signature reveals alterations underlying deficient homologous recombination repair in breast cancer

A unique subset of glycolytic tumour-propagating cells drives squamous cell carcinoma

ACTL6A Is Co-Amplified with p63 in Squamous Cell Carcinoma to Drive YAP Activation, Regenerative Proliferation, and Poor Prognosis.

Aneuploidy and a deregulated DNA damage response suggest haploinsufficiency in breast tissues of BRCA2 mutation carriers

BRCA1-Associated Epigenetic Regulation of p73 Mediates an Effector Pathway for Chemosensitivity in Ovarian Carcinoma ⬇️

Basal cell signaling by p63 controls luminal progenitor function and lactation via NRG1.

Bcl-2 blocks cisplatin-induced apoptosis and predicts poor outcome following chemoradiation treatment in advanced oropharyngeal squamous cell carcinoma

Bioprinting the Cancer Microenvironment

Circadian function in cancer: regulating the DNA damage response.

Circulating oncometabolite 2-hydroxyglutarate is a potential surrogate biomarker in patients with isocitrate dehydrogenase-mutant intrahepatic cholangiocarcinoma

Comparison of the Genomic Landscape Between Primary Breast Cancer in African American Versus White Women and the Association of Racial Differences With Tumor Recurrence

Dexamethasone represses signaling through the mammalian target of rapamycin in muscle cells by enhancing expression of REDD1.

Efficacy of neoadjuvant Cisplatin in triple-negative breast cancer

FGFR2 signaling underlies p63 oncogenic function in squamous cell carcinoma

FOXO-regulated transcription restricts overgrowth of Tsc mutant organs

Frequent Mutation of Isocitrate Dehydrogenase (IDH)1 and IDH2 in Cholangiocarcinoma Identified Through Broad-Based Tumor Genotyping ⬇️

Growth control under stress: mTOR regulation through the REDD1-TSC pathway

Hypoxia regulates TSC1/2-mTOR signaling and tumor suppression through REDD1-mediated 14-3-3 shuttling

Identification of somatically acquired BRCA1/2 mutations by cfDNA analysis in patients with metastatic breast cancer

Mcl-1 and FBW7 control a dominant survival pathway underlying HDAC and Bcl-2 inhibitor synergy in squamous cell carcinoma.

Mutation frequency in 15 common cancer genes in high-risk head and neck squamous cell carcinoma

Mutational analysis and clinical correlation of metastatic colorectal cancer

Negative feedback control of HIF-1 through REDD1-regulated ROS suppresses tumorigenesis

Neoadjuvant Endocrine Therapy for Estrogen Receptor-Positive Breast Cancer: A Systematic Review and Meta-analysis.

PI3K inhibition impairs BRCA1/2 expression and sensitizes BRCA-proficient triple-negative breast cancer to PARP inhibition

Physical association of HDAC1 and HDAC2 with p63 mediates transcriptional repression and tumor maintenance in squamous cell carcinoma

REDD1 loss reprograms lipid metabolism to drive progression of RAS mutant tumors

REDD1, a developmentally regulated transcriptional target of p63 and p53, links p63 to regulation of reactive oxygen species

Rapid targeted mutational analysis of human tumours: a clinical platform to guide personalized cancer medicine

Reciprocal intraepithelial interactions between TP63 and hedgehog signaling regulate quiescence and activation of progenitor elaboration by mammary stem cells.

Regulation of gene expression by WT1 in development and tumorigenesis

Regulation of mTOR and cell growth in response to energy stress by REDD1.

Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex

Standardized decision support in next generation sequencing reports of somatic cancer variants

TBCRC009: A Multicenter Phase II Clinical Trial of Platinum Monotherapy With Biomarker Assessment in Metastatic Triple-Negative Breast Cancer

Targetable signaling pathway mutations are associated with malignant phenotype in IDH-mutant gliomas.

The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1alpha

The integrin alpha(v)beta(3-5) ligand MFG-E8 is a p63/p73 target gene in triple-negative breast cancers but exhibits suppressive functions in ER(+) and erbB2(+) breast cancers

The molecular pathogenesis of head and neck squamous cell carcinoma ⬇️

The p63/p73 network mediates chemosensitivity to cisplatin in a biologically defined subset of primary breast cancers

Tumor-specific p73 up-regulation mediates p63 dependence in squamous cell carcinoma

Women's Health Issues for BRCA Mutation Carriers

Yap tunes airway epithelial size and architecture by regulating the identity, maintenance, and self-renewal of stem cells

Young adult daughters of BRCA1/2 positive mothers: what do they know about hereditary cancer and how much do they worry?

mTOR Activity Under Hypoxia ⬇️

p63 and p73: life and death in squamous cell carcinoma

p63 mediates survival in squamous cell carcinoma by suppression of p73-dependent apoptosis

p63 regulates an adhesion programme and cell survival in epithelial cells

ΔNp63α Silences a miRNA Program to Aberrantly Initiate a Wound-Healing Program That Promotes TGFβ-Induced Metastasis

ΔNp63α represses anti-proliferative genes via H2A.Z deposition.