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Lista de obras de Roberto Ciccocioppo

3-(4-Chloro-2-morpholin-4-yl-thiazol-5-yl)-8-(1-ethylpropyl)-2,6-dimethyl-imidazo[1,2-b]pyridazine: a novel brain-penetrant, orally available corticotropin-releasing factor receptor 1 antagonist with efficacy in animal models of alcoholism.

artículo científico publicado en 2007

A Novel, Orally Bioavailable Nociceptin Receptor Antagonist, LY2940094, Reduces Ethanol Self-Administration and Ethanol Seeking in Animal Models

artículo científico publicado en 2016

A novel brain penetrant NPS receptor antagonist, NCGC00185684, blocks alcohol-induced ERK-phosphorylation in the central amygdala and decreases operant alcohol self-administration in rats

scientific journal article

A preclinical model of binge eating elicited by yo-yo dieting and stressful exposure to food: effect of sibutramine, fluoxetine, topiramate, and midazolam

artículo científico publicado en 2009

AT-1001: a high-affinity α3β4 nAChR ligand with novel nicotine-suppressive pharmacology

artículo científico publicado en 2015

Activation of Hypocretin-1/Orexin-A Neurons Projecting to the Bed Nucleus of the Stria Terminalis and Paraventricular Nucleus Is Critical for Reinstatement of Alcohol Seeking by Neuropeptide S.

artículo científico publicado en 2015

Activation of PPARγ Attenuates the Expression of Physical and Affective Nicotine Withdrawal Symptoms through Mechanisms Involving Amygdala and Hippocampus Neurotransmission

artículo científico publicado en 2019

Activation of PPARγ by pioglitazone potentiates the effects of naltrexone on alcohol drinking and relapse in msP rats

artículo científico publicado en 2013

Activation of brain NOP receptors attenuates acute and protracted alcohol withdrawal symptoms in the rat.

artículo científico publicado en 2011

Activation of nuclear PPARγ receptors by the antidiabetic agent pioglitazone suppresses alcohol drinking and relapse to alcohol seeking.

artículo científico publicado en 2011

Activation of peroxisome proliferator-activated receptor γ reduces alcohol drinking and seeking by modulating multiple mesocorticolimbic regions in rats

artículo científico publicado en 2020

Activation of the nociceptin/orphanin FQ system is unable to reverse CRF2 receptor mediated anorexia in the rat

scientific journal article

Acute Elevations in Cortisol Increase the In Vivo Binding of [11C]NOP-1A to Nociceptin Receptors: A Novel Imaging Paradigm to Study the Interaction Between Stress- and Antistress-Regulating Neuropeptides

artículo científico publicado en 2019

Acute and subchronic antinociceptive effects of nociceptin/orphanin FQ receptor agonists infused by intrathecal route in rats

scholarly article by Laura Micheli et al published May 2015 in European Journal of Pharmacology

Acute stress enhances the expression of neuroprotection- and neurogenesis-associated genes in the hippocampus of a mouse restraint model

artículo científico publicado en 2016

Analgesic tolerance to morphine is regulated by PPARγ.

artículo científico publicado en 2014

Animal models of motivation for drinking in rodents with a focus on opioid receptor neuropharmacology

artículo científico publicado en 2003

Attenuation of ethanol self-administration and of conditioned reinstatement of alcohol-seeking behaviour by the antiopioid peptide nociceptin/orphanin FQ in alcohol-preferring rats

artículo científico publicado en 2003

Autoradiographic analysis of 5-hydroxytryptamine 5-HT2A binding sites in the rat brain after chronic intragastric ethanol treatments.

artículo científico publicado en 2002

Biomarkers of hippocampal gene expression in a mouse restraint chronic stress model

artículo científico publicado en 2015

Blockade of gamma-aminobutyric acid receptors does not modify the inhibiton of ethanol intake induced by Hypericum perforatum in rats

artículo científico publicado en 2002

Brain functional connectivity alterations in a rat model of excessive alcohol drinking: A resting-state network analysis.

artículo científico publicado en 2017

Building better strategies to develop new medications in Alcohol Use Disorder: Learning from past success and failure to shape a brighter future

scientific article published on 18 May 2019

Buprenorphine reduces alcohol drinking through activation of the nociceptin/orphanin FQ-NOP receptor system

artículo científico publicado en 2006

Buprenorphine requires concomitant activation of NOP and MOP receptors to reduce cocaine consumption.

artículo científico publicado en 2017

CB1 and ethanol effects on glutamatergic transmission in the central amygdala of male and female msP and Wistar rats.

artículo científico publicado en 2017

Caloric restriction increases the sensitivity to the hyperphagic effect of nociceptin/orphanin FQ limiting its ability to reduce binge eating in female rats.

artículo científico publicado en 2013

Cannabinoid CB1 receptor antagonism reduces conditioned reinstatement of ethanol-seeking behavior in rats

artículo científico publicado en 2005

Cebranopadol, a Mixed Opioid Agonist, Reduces Cocaine Self-administration through Nociceptin Opioid and Mu Opioid Receptors.

artículo científico publicado en 2017

Chronic THC during adolescence increases the vulnerability to stress-induced relapse to heroin seeking in adult rats

artículo científico publicado en 2013

Chronic treatment with novel brain-penetrating selective NOP receptor agonist MT-7716 reduces alcohol drinking and seeking in the rat

artículo científico publicado en 2014

Constitutive Increases in Amygdalar Corticotropin-Releasing Factor and Fatty Acid Amide Hydrolase Drive an Anxious Phenotype

artículo científico publicado en 2017

Decreased Nociceptin Receptors Are Related to Resilience and Recovery in College Women Who Have Experienced Sexual Violence: Therapeutic Implications for Posttraumatic Stress Disorder

scientific article published on 04 April 2019

Dysregulation of nociceptin/orphanin FQ activity in the amygdala is linked to excessive alcohol drinking in the rat.

artículo científico publicado en 2008

Early life exposure to permethrin: a progressive animal model of Parkinson's disease

artículo científico publicado en 2016

Effect of Hypericum perforatum CO2 extract on the motivational properties of ethanol in alcohol-preferring rats

artículo científico publicado en 2005

Effect of neuropeptide S receptor antagonists and partial agonists on palatable food consumption in the rat

scientific journal article

Effect of novel NOP receptor ligands on food intake in rats

artículo científico publicado en 2006

Effect of salidroside, active principle of Rhodiola rosea extract, on binge eating.

artículo científico publicado en 2010

Effect of selective blockade of mu(1) or delta opioid receptors on reinstatement of alcohol-seeking behavior by drug-associated stimuli in rats

artículo científico publicado en 2002

Effect of the cannabinoid CB1 receptor antagonist SR-141716A on ethanol self-administration and ethanol-seeking behaviour in rats

artículo científico publicado en 2005

Effects of early life permethrin exposure on spatial working memory and on monoamine levels in different brain areas of pre-senescent rats

artículo científico publicado en 2012

Efficacy of a Combination of N-Palmitoylethanolamide, Beta-Caryophyllene, Carnosic Acid, and Myrrh Extract on Chronic Neuropathic Pain: A Preclinical Study

artículo científico publicado en 2019

Emerging targets for addiction neuropharmacology: From mechanisms to therapeutics

artículo científico publicado en 2015

Endocannabinoid regulation of acute and protracted nicotine withdrawal: effect of FAAH inhibition

artículo científico publicado en 2011

Enhanced GABAergic transmission in the central nucleus of the amygdala of genetically selected Marchigian Sardinian rats: alcohol and CRF effects

artículo científico publicado en 2012

Epigenetic regulation of nociceptin/orphanin FQ and corticotropin-releasing factor system genes in frustration stress-induced binge-like palatable food consumption.

artículo científico publicado en 2015

Evaluation of Alcohol Preference and Drinking in msP Rats Bearing a Crhr1 Promoter Polymorphism.

artículo científico publicado en 2018

Evidence of a PPARγ-mediated mechanism in the ability of Withania somnifera to attenuate tolerance to the antinociceptive effects of morphine

scientific article published on 29 November 2018

Further evidence for the involvement of the PPARγ system on alcohol intake and sensitivity in rodents

artículo científico publicado en 2020

Further studies on the pharmacological profile of the neuropeptide S receptor antagonist SHA 68.

artículo científico publicado en 2010

Genetic Deletion of Neuronal PPARγ Enhances the Emotional Response to Acute Stress and Exacerbates Anxiety: An Effect Reversed by Rescue of Amygdala PPARγ Function.

artículo científico publicado en 2016

Genetic Deletion of the Nociceptin/Orphanin FQ Receptor in the Rat Confers Resilience to the Development of Drug Addiction.

artículo científico publicado en 2016

Genetically selected Marchigian Sardinian alcohol-preferring (msP) rats: an animal model to study the neurobiology of alcoholism

artículo científico publicado en 2006

Genetically selected alcohol preferring rats to model human alcoholism

artículo científico publicado en 2013

Glutamatergic transmission in the central nucleus of the amygdala is selectively altered in Marchigian Sardinian alcohol-preferring rats: Alcohol and CRF effects

artículo científico publicado en 2015

Grand Challenge in Psychopharmacology: Setting Priorities to Shape a Bright Future

artículo científico publicado en 2017

Hypericum perforatum CO2 Extract and Opioid Receptor Antagonists Act Synergistically to Reduce Ethanol Intake in Alcohol‐Preferring Rats ⬇️

artículo científico publicado el 1 de octubre de 2003

Hypothalamic CRF1 receptor mechanisms are not sufficient to account for binge-like palatable food consumption in female rats

artículo científico publicado en 2017

Hypothalamic neuropeptide S receptor blockade decreases discriminative cue-induced reinstatement of cocaine seeking in the rat.

artículo científico publicado en 2012

Impaired hypothalamic feedback dysregulates brain glucocorticoid signaling in genetically-selected Marchigian Sardinian alcohol-preferring rats

artículo científico publicado en 2020

Increase of brain endocannabinoid anandamide levels by FAAH inhibition and alcohol abuse behaviours in the rat.

artículo científico publicado en 2008

Increased perioculomotor urocortin 1 immunoreactivity in genetically selected alcohol preferring rats.

artículo científico publicado en 2009

Inhibition of fatty acid amide hydrolase in the central amygdala alleviates co-morbid expression of innate anxiety and excessive alcohol intake.

artículo científico publicado en 2017

Introduction to Large-Scale Gene Expression Data Analysis

article

Involvement of the N/OFQ-NOP system in rat morphine antinociceptive tolerance: Are astrocytes the crossroad?

artículo científico publicado en 2018

MT-7716, a novel selective nonpeptidergic NOP receptor agonist, effectively blocks ethanol-induced increase in GABAergic transmission in the rat central amygdala.

artículo científico publicado en 2014

MT-7716, a potent NOP receptor agonist, preferentially reduces ethanol seeking and reinforcement in post-dependent rats

artículo científico publicado en 2014

Melanin-concentrating hormone receptor 1 (MCH1-R) antagonism: reduced appetite for calories and suppression of addictive-like behaviors

artículo científico publicado en 2012

Memory impairment following combined exposure to delta(9)-tetrahydrocannabinol and ethanol in rats

artículo científico publicado en 2002

Methylation of OPRL1 mediates the effect of psychosocial stress on binge drinking in adolescents

artículo científico publicado en 2017

Microarrays in Neuroscience

Microarrays--the challenge of preparing brain tissue samples.

artículo científico publicado en 2005

Microstructural White Matter Alterations in Men With Alcohol Use Disorder and Rats With Excessive Alcohol Consumption During Early Abstinence

artículo científico publicado en 2019

Modification of anxiety-like behaviors by nociceptin/orphanin FQ (N/OFQ) and time-dependent changes in N/OFQ-NOP gene expression following ethanol withdrawal

artículo científico publicado en 2012

Morphine dependence is associated with changes in neuropeptide S receptor expression and function in rat brain

artículo científico publicado en 2013

Multi-modal MRI classifiers identify excessive alcohol consumption and treatment effects in the brain.

artículo científico publicado en 2016

NOP Receptor Agonist Ro 64-6198 Decreases Escalation of Cocaine Self-Administration in Rats Genetically Selected for Alcohol Preference

artículo científico publicado en 2019

NOP Receptor Antagonists Decrease Alcohol Drinking in the Dark in C57BL/6J Mice

scientific article published on 21 August 2019

NOP receptor antagonism reduces alcohol drinking in male and female rats through mechanisms involving the central amygdala and ventral tegmental area

scientific article published on 03 February 2020

NOP-Related Mechanisms in Substance Use Disorders

scientific article published on 01 January 2019

Neonatal exposure to permethrin pesticide causes lifelong fear and spatial learning deficits and alters hippocampal morphology of synapses

scientific article published on 29 March 2014

Neurokinin 1 receptor blockade in the medial amygdala attenuates alcohol drinking in rats with innate anxiety but not in Wistar rats.

artículo científico publicado en 2015

Neuropeptide S differently modulates alcohol-related behaviors in alcohol-preferring and non-preferring rats.

artículo científico publicado en 2016

Neuropeptide S facilitates cue-induced relapse to cocaine seeking through activation of the hypothalamic hypocretin system ⬇️

artículo científico publicado el 25 de octubre de 2010

Neuropeptide S receptor gene expression in alcohol withdrawal and protracted abstinence in postdependent rats.

artículo científico publicado en 2009

Nociceptin Receptors Upregulated in Cocaine Use Disorder: A Positron Emission Tomography Imaging Study Using [11C]NOP-1A

scientific article published on 06 May 2019

Nociceptin Receptors in Alcohol Use Disorders: A Positron Emission Tomography Study Using [11C]NOP-1A.

artículo científico publicado en 2017

Nociceptin/orphanin FQ acts as a functional antagonist of corticotropin-releasing factor to inhibit its anorectic effect

artículo científico publicado en 2004

Oxytocin Reduces Alcohol Cue-Reactivity in Alcohol-Dependent Rats and Humans

artículo científico publicado en 2017

PPARc activation attenuates opioid consumption and modulates mesolimbic dopamine transmission

artículo científico publicado en 2015

PPARα/CB1 receptor dual ligands as a novel therapy for alcohol use disorder: Evaluation of a novel oleic acid conjugate in preclinical rat models

scientific article published on 06 September 2018

PPARγ activation attenuates opioid consumption and modulates mesolimbic dopamine transmission

artículo científico publicado en 2014

Paradoxical response to the sedative effects of diazepam and alcohol in C57BL/6J mice lacking the neuropeptide S receptor

artículo científico publicado en 2014

Perceived parental care during childhood, ACTH, cortisol and nicotine dependence in the adult

artículo científico publicado en 2016

Perinatal exposure to delta-9-tetrahydrocannabinol causes enduring cognitive deficits associated with alteration of cortical gene expression and neurotransmission in rats.

artículo científico publicado en 2007

Peroxisome proliferator-activated receptor (PPAR) agonists as promising new medications for drug addiction: preclinical evidence

scientific article published on June 2013

Persistent increase of alcohol-seeking evoked by neuropeptide S: an effect mediated by the hypothalamic hypocretin system

artículo científico publicado en 2009

Pharmacological and Behavioral Effects of the Synthetic Cannabinoid AKB48 in Rats

scientific article published on 30 October 2019

Pharmacological blockade of corticotropin-releasing hormone receptor 1 (CRH1R) reduces voluntary consumption of high alcohol concentrations in non-dependent Wistar rats

artículo científico publicado en 2011

Pharmacological characterisation of [(pX)Phe 4 ]nociceptin(1-13)NH 2 analogues

scholarly article by Anna Rizzi et al published 1 June 2002 in Naunyn-Schmiedeberg's Archives of Pharmacology

Pharmacological characterization of the nociceptin receptor which mediates reduction of alcohol drinking in rats

artículo científico publicado en 2002

Pharmacological characterization of the nociceptin/orphanin FQ receptor antagonist SB-612111 [(-)-cis-1-methyl-7-[[4-(2,6-dichlorophenyl)piperidin-1-yl]methyl]-6,7,8,9-tetrahydro-5H-benzocyclohepten-5-ol]: in vivo studies.

artículo científico publicado en 2007

Pharmacology and toxicology of Cannabis derivatives and endocannabinoid agonists

artículo científico publicado en 2010

Pioglitazone attenuates the opioid withdrawal and vulnerability to relapse to heroin seeking in rodents

artículo científico publicado en 2016

Pioglitazone, a PPARγ agonist, reduces nicotine craving in humans, with marginal effects on abuse potential

artículo científico publicado en 2017

Polymorphism in the corticotropin-releasing factor receptor 1 (CRF1-R) gene plays a role in shaping the high anxious phenotype of Marchigian Sardinian alcohol-preferring (msP) rats

artículo científico publicado en 2014

Pre-exposure to environmental cues predictive of food availability elicits hypothalamic-pituitary-adrenal axis activation and increases operant responding for food in female rats.

artículo científico publicado en 2009

Pregabalin reduces alcohol drinking and relapse to alcohol seeking in the rat.

artículo científico publicado en 2011

Pregabalin reduces cocaine self-administration and relapse to cocaine seeking in the rat.

artículo científico publicado en 2012

Promising medications for cocaine dependence treatment.

scientific article published on May 2011

Protection against alcohol-induced neuronal and cognitive damage by the PPARγ receptor agonist pioglitazone

artículo científico publicado en 2017

Reduced limbic metabolism and fronto-cortical volume in rats vulnerable to alcohol addiction

artículo científico publicado en 2012

Region-specific down-regulation of Crhr1 gene expression in alcohol-preferring msP rats following ad lib access to alcohol

artículo científico publicado en 2007

Reinstatement of ethanol-seeking behavior by drug cues following single versus multiple ethanol intoxication in the rat: effects of naltrexone

artículo científico publicado en 2003

Restraint stress alters nociceptin/orphanin FQ and CRF systems in the rat central amygdala: significance for anxiety-like behaviors.

artículo científico publicado en 2014

Reversal of stress- and CRF-induced anorexia in rats by the synthetic nociceptin/orphanin FQ receptor agonist, Ro 64-6198.

artículo científico publicado en 2002

Revisiting intragastric ethanol intubation as a dependence induction method for studies of ethanol reward and motivation in rats

artículo científico publicado en 2009

Role of Hypothalamic-Pituitary-Adrenal axis and corticotropin-releasing factor stress system on cue-induced relapse to alcohol seeking

artículo científico publicado en 2016

Role of a genetic polymorphism in the corticotropin-releasing factor receptor 1 gene in alcohol drinking and seeking behaviors of marchigian sardinian alcohol-preferring rats

artículo científico publicado en 2013

Role of bed nucleus of the stria terminalis corticotrophin-releasing factor receptors in frustration stress-induced binge-like palatable food consumption in female rats with a history of food restriction

artículo científico publicado en 2014

Role of cannabinoidergic mechanisms in ethanol self-administration and ethanol seeking in rat adult offspring following perinatal exposure to Delta9-tetrahydrocannabinol

artículo científico publicado en 2007

Role of innate and drug-induced dysregulation of brain stress and arousal systems in addiction: Focus on corticotropin-releasing factor, nociceptin/orphanin FQ, and orexin/hypocretin

artículo científico publicado en 2009

Role of orexin-1 receptor mechanisms on compulsive food consumption in a model of binge eating in female rats

artículo científico publicado en 2012

Role of the satiety factor oleoylethanolamide in alcoholism

artículo científico publicado en 2015

Shaping vulnerability to addiction - the contribution of behavior, neural circuits and molecular mechanisms.

artículo científico

Stimuli associated with a single cocaine experience elicit long-lasting cocaine-seeking

artículo científico publicado en 2004

Stratified medicine for mental disorders

artículo científico publicado en 2013

Stress-related neuropeptides and addictive behaviors: beyond the usual suspects

artículo científico publicado en 2012

Stress-related neuropeptides and alcoholism: CRH, NPY, and beyond

artículo científico publicado en 2009

Sub-dimensions of Alcohol Use Disorder in Alcohol Preferring and Non-preferring Rats, a Comparative Study

artículo científico publicado en 2019

The PPARγ Agonist Pioglitazone Fails to Alter the Abuse Potential of Heroin, But Does Reduce Heroin Craving and Anxiety

artículo científico publicado en 2018

The anandamide transport inhibitor AM404 reduces ethanol self-administration.

artículo científico publicado en 2007

The bed nucleus is a neuroanatomical substrate for the anorectic effect of corticotropin-releasing factor and for its reversal by nociceptin/orphanin FQ.

artículo científico publicado en 2003

The biology of Nociceptin/Orphanin FQ (N/OFQ) related to obesity, stress, anxiety, mood, and drug dependence

artículo científico publicado en 2013

The dorsal subiculum mediates the acquisition of conditioned reinstatement of cocaine-seeking

artículo científico publicado en 2008

The effects of acamprosate and neramexane on cue-induced reinstatement of ethanol-seeking behavior in rat.

artículo científico publicado en 2005

The effects of pioglitazone, a PPARγ receptor agonist, on the abuse liability of oxycodone among nondependent opioid users

artículo científico publicado en 2015

The genetic of alcoholism: learning from 50 years of research

artículo científico publicado en 2006

The nociceptin/orphanin FQ/NOP receptor system as a target for treatment of alcohol abuse: a review of recent work in alcohol-preferring rats

artículo científico publicado en 2003

The paraventricular nucleus of the hypothalamus is a neuroanatomical substrate for the inhibition of palatable food intake by neuropeptide S

scientific journal article

The role of the neuropeptide S system in addiction: focus on its interaction with the CRF and hypocretin/orexin neurotransmission

artículo científico

Translational approach to develop novel medications on alcohol addiction: focus on neuropeptides.

artículo científico publicado en 2013

Translational dynamics of alcohol tolerance of preclinical models and human laboratory studies

artículo científico publicado en 2020

Varenicline decreases nicotine but not alcohol self-administration in genetically selected Marchigian Sardinian alcohol-preferring (msP) rats.

artículo científico publicado en 2015

phMRI, neurochemical and behavioral responses to psychostimulants distinguishing genetically selected alcohol-preferring from genetically heterogenous rats

article

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